Published in Clin Pharmacokinet on January 01, 2005
Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction. Eur J Clin Pharmacol (2008) 2.36
The clinical implications of ageing for rational drug therapy. Eur J Clin Pharmacol (2008) 1.56
The Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cells. PLoS One (2012) 1.54
Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo. World J Gastroenterol (2006) 1.39
Three-dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations. J Struct Biol (2010) 1.13
Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers. Immun Ageing (2007) 1.06
The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells. Am J Physiol Gastrointest Liver Physiol (2008) 1.05
Age-related changes in the hepatic microcirculation in mice. Exp Gerontol (2007) 1.02
Age-related changes in the hepatic pharmacology and toxicology of paracetamol. Curr Gerontol Geriatr Res (2011) 1.01
Liver immunology. Compr Physiol (2013) 0.99
Population pharmacokinetic and pharmacodynamic analysis of linezolid and a hematologic side effect, thrombocytopenia, in Japanese patients. Antimicrob Agents Chemother (2011) 0.96
Liver sinusoidal endothelial fenestrations in caveolin-1 knockout mice. Microcirculation (2010) 0.89
Clinical implications of changes in hepatic drug metabolism in older people. Ther Clin Risk Manag (2005) 0.86
Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid. Exp Gerontol (2007) 0.85
Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats. J Gerontol A Biol Sci Med Sci (2011) 0.84
Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity. Am J Physiol Endocrinol Metab (2011) 0.84
Clinical pharmacology of chemotherapy agents in older people with cancer. Curr Gerontol Geriatr Res (2011) 0.83
Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells. J Gerontol A Biol Sci Med Sci (2010) 0.82
Dose adjustment in patients with liver cirrhosis: impact on adverse drug reactions and hospitalizations. Eur J Clin Pharmacol (2013) 0.80
A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models. Theor Biol Med Model (2013) 0.79
Caloric restriction versus drug therapy to delay the onset of aging diseases and extend life. Age (Dordr) (2005) 0.79
A Sieve-Raft Hypothesis for the regulation of endothelial fenestrations. Comput Struct Biotechnol J (2013) 0.78
Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network. Microcirculation (2008) 0.78
Pharmacokinetic drug interactions in liver disease: An update. World J Gastroenterol (2016) 0.75
Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance. Aging Cell (2016) 0.75
Relevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage Adjustments. Ther Adv Infect Dis (2014) 0.75
T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells. Hepatology (2006) 2.30
Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat. Hepatology (2005) 2.00
A systematic review of amnestic and non-amnestic mild cognitive impairment induced by anticholinergic, antihistamine, GABAergic and opioid drugs. Drugs Aging (2012) 1.97
Hepatic pseudocapillarisation and atherosclerosis in ageing. Lancet (2002) 1.88
Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer. Clin Cancer Res (2006) 1.64
Predictors of vinorelbine pharmacokinetics and pharmacodynamics in patients with cancer. J Clin Oncol (2006) 1.51
Fenitrothion: toxicokinetics and toxicologic evaluation in human volunteers. Environ Health Perspect (2003) 1.48
Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy. Lancet Oncol (2003) 1.45
Fenestrations and lipoproteins. Cardiovasc Pathol (2010) 1.38
Factors affecting cytochrome P-450 3A activity in cancer patients. Clin Cancer Res (2004) 1.36
Old age and the hepatic sinusoid. Anat Rec (Hoboken) (2008) 1.14
Hepatic sinusoidal pseudocapillarization with aging in the non-human primate. Exp Gerontol (2003) 1.11
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients. Clin Cancer Res (2008) 1.08
The effects of oxidative stress on the liver sieve. J Hepatol (2004) 1.03
Prevalence and impact of fall-risk-increasing drugs, polypharmacy, and drug-drug interactions in robust versus frail hospitalised falls patients: a prospective cohort study. Drugs Aging (2014) 1.02
Hyperlipidemia and surfactants: the liver sieve is a link. Atherosclerosis (2006) 1.00
Sequence determinants of innate immune activation by short interfering RNAs. BMC Immunol (2009) 0.98
Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease. Rev Environ Health (2002) 0.96
Liver dysfunction and heart failure. Am J Cardiol (2003) 0.95
Population pharmacokinetics of weekly docetaxel in patients with advanced cancer. Br J Clin Pharmacol (2004) 0.95
Baseline nutritional assessment in advanced cancer patients receiving palliative chemotherapy. Nutr Cancer (2003) 0.94
A systematic review of the emerging definition of 'deprescribing' with network analysis: implications for future research and clinical practice. Br J Clin Pharmacol (2015) 0.93
Hepatic pseudocapillarization in aged mice. Exp Gerontol (2005) 0.91
Rapid quantitation of plasma 2'-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.91
Marked changes of the hepatic sinusoid in a transgenic mouse model of acute immune-mediated hepatitis. J Hepatol (2006) 0.88
Age-related changes in the liver sinusoidal endothelium: a mechanism for dyslipidemia. Ann N Y Acad Sci (2007) 0.88
A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer. Cancer Chemother Pharmacol (2005) 0.88
Postprandial systolic blood pressure responses of older people in residential care: association with risk of falling. Gerontology (2003) 0.87
The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours. Oncol Rep (2003) 0.87
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients. Br J Clin Pharmacol (2006) 0.87
Intended transcriptional silencing with siRNA results in gene repression through sequence-specific off-targeting. RNA (2009) 0.86
Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer. Clin Pharmacol Ther (2005) 0.85
Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid. Exp Gerontol (2007) 0.85
Why teach human anatomy at Otago School of Medical Sciences? N Z Med J (2010) 0.84
Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study. Dement Geriatr Cogn Disord (2011) 0.83
Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505. J Biol Chem (2007) 0.83
The Tn antigen-specific lectin from ground ivy is an insecticidal protein with an unusual physiology. Plant Physiol (2003) 0.82
The importance of tumor glucuronidase in the activation of irinotecan in a mouse xenograft model. J Pharmacol Exp Ther (2002) 0.81
A cluster-randomized controlled trial of a computerized antithrombotic risk assessment tool to optimize stroke prevention in general practice: a study protocol. BMC Health Serv Res (2014) 0.81
The effects of old age on hepatic stellate cells. Curr Gerontol Geriatr Res (2011) 0.81
Entacapone-induced hepatotoxicity and hepatic dysfunction. Mov Disord (2002) 0.80
Dimethylthetin treatment causes diffuse alveolar lung damage: a pilot study in a sheep model of Continuous Ambulatory Peritoneal Dialysis (CAPD). Exp Toxicol Pathol (2006) 0.79
Interfering ribonucleic acids that suppress expression of multiple unrelated genes. BMC Biotechnol (2009) 0.79
The liver sieve and gene therapy. Blood (2003) 0.79
Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines. Oncol Rep (2004) 0.78
Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network. Microcirculation (2008) 0.78
Diversity of risk factors for stroke: the putative roles and mechanisms of depression and air pollution. J Neurol Sci (2007) 0.77
The effect of feeding and fasting on fenestrations in the liver sinusoidal endothelial cell. Pathology (2010) 0.77
Thirty-five years of liver sinusoidal cells: Eddie Wisse in retirement. Hepatology (2003) 0.77
Age-related alteration in hepatic disposition of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and pesticides. Pharmacol Toxicol (2002) 0.76
Preliminary analysis of the sinusoidal endothelium and space of Disse in ageing Papio hamadrayas. Comp Hepatol (2004) 0.75
Loperamide inhibits the biliary excretion of irinotecan (CPT-11) in the rat isolated perfused liver. J Pharm Pharmacol (2005) 0.75
Population pharmacokinetics of raltitrexed in patients with advanced solid tumours. Br J Clin Pharmacol (2004) 0.75
Predicting the toxicity of weekly docetaxel in advanced cancer. Clin Pharmacokinet (2006) 0.75
The role of the OncPal deprescribing guideline in end-of-life care. Support Care Cancer (2014) 0.75
Physical functioning measures and risk of falling in older people living in residential aged care facilities. Ther Adv Musculoskelet Dis (2011) 0.75
Nail in the coffin. Lancet (2003) 0.75
What's happening - Scotblood 2006 advances in immunetolerance, information technology, microarrays and pathogen inactivation in transfusion medicine. Transfus Apher Sci (2006) 0.75
Who needs budgets? Harv Bus Rev (2003) 0.75
Scotblood 2011 features advances in translational medicine, haemopoietic progenitor cells and milestones of blood banking systems. Transfus Apher Sci (2011) 0.75
Correction: Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis. PLoS One (2017) 0.75
Ultrastructural changes in hepatic sinusoidal endothelial cells acutely exposed to colloidal iron. Exp Toxicol Pathol (2003) 0.75
Scotblood 2007: Tackling local and global issues in transfusion medicine - donor recruitment, effective use of blood, stem cell plasticity, and vCJD. Transfus Apher Sci (2008) 0.75
Pemetrexed: single-agent and combination phase I study overview. Semin Oncol (2002) 0.75
Differential Effects of Kupffer Cell Inactivation on Inflammation and The Liver Sieve Following Caecal-Ligation and Puncture-Induced Sepsis in Mice. Shock (2017) 0.75
Scotblood 2008 celebrates 60th anniversary of the NHS through past, present, and future of transfusion medicine, encompassing Hepatitis C Scottish Odyssey, nursing, translational medicine and trauma. Transfus Apher Sci (2008) 0.75
Hepatic phospholipid changes induced by sustained oxygen supplementation. Pharmacol Toxicol (2002) 0.75
Clinical pharmacology. Med J Aust (2002) 0.75
Scotblood 2010: key presentations of the past, present, and future of transfusion medicine to mark Scottish national blood transfusion service (SNBTS) anniversaries. Transfus Apher Sci (2011) 0.75
SCOTBLOOD 2009: the quest for understanding vCJD; Claudia's Trachea implantation; transfusion triggers; Scottish histocompatibility and immunogenetics network; and islet cell transplantation. Transfus Apher Sci (2010) 0.75