| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity.
|
J Med Chem
|
2008
|
1.04
|
|
2
|
Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.
|
J Med Chem
|
2008
|
0.91
|
|
3
|
Rational approach to discover multipotent anti-Alzheimer drugs.
|
J Med Chem
|
2005
|
0.88
|
|
4
|
Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease.
|
Neurotoxicology
|
2013
|
0.86
|
|
5
|
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.
|
J Med Chem
|
2007
|
0.84
|
|
6
|
Multitargeted drugs discovery: balancing anti-amyloid and anticholinesterase capacity in a single chemical entity.
|
Bioorg Med Chem Lett
|
2010
|
0.82
|
|
7
|
Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects.
|
J Med Chem
|
2006
|
0.82
|
|
8
|
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents.
|
J Med Chem
|
2010
|
0.81
|
|
9
|
Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds.
|
J Med Chem
|
2005
|
0.80
|
|
10
|
Relevance of apple consumption for protection against oxidative damage induced by hydrogen peroxide in human lymphocytes.
|
Br J Nutr
|
2007
|
0.78
|
|
11
|
Red chicory (Cichorium intybus L. cultivar) as a potential source of antioxidant anthocyanins for intestinal health.
|
Oxid Med Cell Longev
|
2013
|
0.78
|
|
12
|
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.
|
Eur J Med Chem
|
2011
|
0.77
|
|
13
|
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents.
|
Eur J Med Chem
|
2012
|
0.77
|
|
14
|
Investigation of the photochemical properties and in vitro phototoxic potential of bumetanide.
|
Photochem Photobiol Sci
|
2003
|
0.76
|
|
15
|
Diet and risk of cancer.
|
Lancet
|
2003
|
0.75
|
|
16
|
Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors.
|
Bioorg Med Chem
|
2006
|
0.75
|