PubRank

R R Ali

Author PubWeight™ 71.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Retinal repair by transplantation of photoreceptor precursors. Nature 2006 6.73
2 Restoration of vision after transplantation of photoreceptors. Nature 2012 3.91
3 In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium. Gene Ther 2001 1.93
4 Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors. Exp Eye Res 2008 1.78
5 Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8. Gene Ther 2007 1.66
6 Gene therapy progress and prospects: the eye. Gene Ther 2006 1.66
7 Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina. Cell Transplant 2010 1.64
8 Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Gene Ther 2006 1.59
9 Effective transplantation of photoreceptor precursor cells selected via cell surface antigen expression. Stem Cells 2011 1.50
10 Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy. Gene Ther 2005 1.48
11 Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations. Gene Ther 2009 1.48
12 Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells. Mol Ther 2001 1.47
13 Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina. Hum Mol Genet 2001 1.46
14 An immune response after intraocular administration of an adenoviral vector containing a beta galactosidase reporter gene slows retinal degeneration in the rd mouse. Br J Ophthalmol 2001 1.42
15 Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells. Hum Mol Genet 2010 1.42
16 [Progress in somatic gene therapy of retinal degeneration in the animal model]. Ophthalmologe 2002 1.40
17 High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice. Cell Death Differ 1998 1.38
18 AAV-mediated gene therapy for retinal disorders: from mouse to man. Gene Ther 2008 1.36
19 Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther 2002 1.36
20 An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene: implications for the origin of CpG islands. Mol Cell Biol 1998 1.34
21 Clinical characterisation of a family with retinal dystrophy caused by mutation in the Mertk gene. Br J Ophthalmol 2006 1.24
22 Novel antisense oligonucleotides targeting TGF-beta inhibit in vivo scarring and improve surgical outcome. Gene Ther 2003 1.17
23 Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2Rd2/Rd2 model of retinal degeneration. Gene Ther 2003 1.17
24 Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. Hum Gene Ther 1998 1.16
25 Cell transplantation strategies for retinal repair. Prog Brain Res 2009 1.14
26 Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX. Gene Ther 2006 1.10
27 Progress and prospects: gene therapy clinical trials (part 1). Gene Ther 2007 1.09
28 Gene therapy in the second eye of RPE65-deficient dogs improves retinal function. Gene Ther 2010 1.09
29 EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV. Gene Ther 2006 1.07
30 Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina. Gene Ther 2003 1.06
31 RPE65 gene therapy slows cone loss in Rpe65-deficient dogs. Gene Ther 2012 1.05
32 Success in sight: The eyes have it! Ocular gene therapy trials for LCA look promising. Gene Ther 2008 1.02
33 Stable and efficient intraocular gene transfer using pseudotyped EIAV lentiviral vectors. J Gene Med 2006 0.99
34 AAV-mediated knockdown of peripherin-2 in vivo using miRNA-based hairpins. Gene Ther 2009 0.98
35 Ocular gene delivery using lentiviral vectors. Gene Ther 2011 0.97
36 Lentiviral-vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis. Gene Ther 2008 0.96
37 Immune responses limit adenovirally mediated gene expression in the adult mouse eye. Gene Ther 1998 0.92
38 Molecular genetics and prospects for therapy of the inherited retinal dystrophies. Curr Opin Genet Dev 2001 0.92
39 Gene supplementation therapy for recessive forms of inherited retinal dystrophies. Gene Ther 2011 0.90
40 Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virus. Vision Res 2002 0.89
41 High-titer recombinant adeno-associated virus production from replicating amplicons and herpes vectors deleted for glycoprotein H. Hum Gene Ther 1999 0.89
42 Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival. Cell Transplant 2012 0.87
43 Molecular therapy in ocular wound healing. Br J Ophthalmol 1999 0.84
44 Experimental gene transfer to the corneal endothelium. Exp Eye Res 2011 0.84
45 Characterization of the regulatory regions in the human desmoglein genes encoding the pemphigus foliaceous and pemphigus vulgaris antigens. Biochem J 1998 0.82
46 [Gene transfer in ophthalmology]. Ophthalmologe 1999 0.81
47 Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization. Gene Ther 2003 0.81
48 Keeping an eye on clinical trials in 2008. Gene Ther 2008 0.80
49 Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina. Mol Cell Neurosci 2008 0.77
50 Optimization of recombinant adeno-associated virus production using an herpes simplex virus amplicon system. J Virol Methods 2001 0.77
51 Gene therapy for noninfectious uveitis. Ocul Immunol Inflamm 2012 0.77
52 Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis. Eur J Immunol 1998 0.76
53 Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient mice. Gene Ther 2011 0.76
54 Gene therapy for retinal degeneration. Ophthalmic Res 1997 0.76
55 Improvement of neuronal visual responses in the superior colliculus in Prph2(Rd2/Rd2) mice following gene therapy. Mol Cell Neurosci 2004 0.76
56 Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse. Ophthalmic Res 2005 0.75
57 Therapy may yet stem from cells in the retina. Br J Ophthalmol 2003 0.75
58 Ocular gene therapy: introduction to the special issue. Gene Ther 2012 0.75