Uffe Holmskov

Author PubWeight™ 81.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Scavenger Receptor Cysteine-Rich (SRCR) domain: an ancient and highly conserved protein module of the innate immune system. Crit Rev Immunol 2004 1.59
2 Collectin 11 (CL-11, CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity. J Immunol 2010 1.47
3 A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D. J Immunol 2005 1.36
4 Innate defense against influenza A virus: activity of human neutrophil defensins and interactions of defensins with surfactant protein D. J Immunol 2006 1.33
5 Tissue localization of human trefoil factors 1, 2, and 3. J Histochem Cytochem 2007 1.31
6 CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D. Eur J Immunol 2003 1.29
7 The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection. PLoS Pathog 2012 1.28
8 Review: Gp-340/DMBT1 in mucosal innate immunity. Innate Immun 2010 1.28
9 Transit-amplifying ductular (oval) cells and their hepatocytic progeny are characterized by a novel and distinctive expression of delta-like protein/preadipocyte factor 1/fetal antigen 1. Am J Pathol 2004 1.25
10 Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology 2009 1.24
11 Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses. Am J Physiol Lung Cell Mol Physiol 2003 1.23
12 Surfactant protein A and surfactant protein D variation in pulmonary disease. Immunobiology 2007 1.21
13 Expression and localization of lung surfactant protein A in human tissues. Am J Respir Cell Mol Biol 2003 1.21
14 The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis. Pharmacol Rev 2011 1.19
15 DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease. Gastroenterology 2007 1.18
16 Ligand specificity of human surfactant protein D: expression of a mutant trimeric collectin that shows enhanced interactions with influenza A virus. J Biol Chem 2005 1.17
17 Surfactant protein D (SP-D) serum levels in patients with community-acquired pneumonia. Clin Immunol 2003 1.12
18 Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D. Respir Res 2007 1.10
19 Species differences in the carbohydrate binding preferences of surfactant protein D. Am J Respir Cell Mol Biol 2006 1.08
20 Respiratory innate immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus. Am J Physiol Lung Cell Mol Physiol 2005 1.08
21 Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1. Am J Pathol 2002 1.07
22 Genetic and environmental influences of surfactant protein D serum levels. Am J Physiol Lung Cell Mol Physiol 2005 1.06
23 Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor. Am J Physiol Lung Cell Mol Physiol 2004 1.06
24 Salivary agglutinin and lung scavenger receptor cysteine-rich glycoprotein 340 have broad anti-influenza activities and interactions with surfactant protein D that vary according to donor source and sialylation. Biochem J 2006 1.03
25 Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin. J Immunol 2009 1.02
26 Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system. J Immunol 2013 1.01
27 Surfactant protein D levels in umbilical cord blood and capillary blood of premature infants. The influence of perinatal factors. Pediatr Res 2006 0.99
28 Molecular and functional characterization of mouse S5D-SRCRB: a new group B member of the scavenger receptor cysteine-rich superfamily. J Immunol 2011 0.98
29 Genetic influences on mannan-binding lectin (MBL) and mannan-binding lectin associated serine protease-2 (MASP-2) activity. Genet Epidemiol 2007 0.98
30 Ficolins and FIBCD1: soluble and membrane bound pattern recognition molecules with acetyl group selectivity. Mol Immunol 2010 0.96
31 Distinctive anti-influenza properties of recombinant collectin 43. Biochem J 2002 0.95
32 Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer. Int J Cancer 2003 0.95
33 The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer. Genes Chromosomes Cancer 2002 0.94
34 Critical role for cross-linking of trimeric lectin domains of surfactant protein D in antiviral activity against influenza A virus. Biochem J 2008 0.94
35 Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication. J Gen Virol 2005 0.93
36 Serum-surfactant SP-D correlates inversely to lung function in cystic fibrosis. J Cyst Fibros 2010 0.92
37 The effects of GH and hormone replacement therapy on serum concentrations of mannan-binding lectin, surfactant protein D and vitamin D binding protein in Turner syndrome. Eur J Endocrinol 2004 0.92
38 DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands. Eur J Immunol 2009 0.91
39 Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas. Genes Chromosomes Cancer 2002 0.91
40 Long-term stability and circadian variation in circulating levels of surfactant protein D. Immunobiology 2009 0.91
41 Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chromosomes Cancer 2004 0.91
42 Surfactant protein D augments bacterial association but attenuates major histocompatibility complex class II presentation of bacterial antigens. Am J Respir Cell Mol Biol 2006 0.91
43 CL-46, a novel collectin highly expressed in bovine thymus and liver. J Immunol 2002 0.90
44 Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer. Carcinogenesis 2005 0.90
45 The SARS coronavirus spike glycoprotein is selectively recognized by lung surfactant protein D and activates macrophages. Immunobiology 2007 0.87
46 Heritability estimates for the constitutional levels of the collectins mannan-binding lectin and lung surfactant protein D. A study of unselected like-sexed mono- and dizygotic twins at the age of 6-9 years. Immunology 2002 0.87
47 The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition. J Biol Chem 2009 0.86
48 Expression and tissue localization of collectin placenta 1 (CL-P1, SRCL) in human tissues. Mol Immunol 2008 0.86
49 A variant form of the human deleted in malignant brain tumor 1 (DMBT1) gene shows increased expression in inflammatory bowel diseases and interacts with dimeric trefoil factor 3 (TFF3). PLoS One 2013 0.86
50 An enzyme-linked immunosorbent assay (ELISA) for quantification of mouse surfactant protein D (SP-D). J Immunol Methods 2007 0.85
51 Viral aggregating and opsonizing activity in collectin trimers. Am J Physiol Lung Cell Mol Physiol 2009 0.85
52 Multimeric and trimeric subunit SP-D are interconvertible structures with distinct ligand interaction. Mol Immunol 2009 0.85
53 Surfactant protein D is proatherogenic in mice. Am J Physiol Heart Circ Physiol 2005 0.85
54 Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis. Arthritis Res Ther 2010 0.84
55 Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain. J Innate Immun 2009 0.83
56 An integrative model on the role of DMBT1 in epithelial cancer. Cancer Detect Prev 2002 0.83
57 Identification and characterization of porcine mannan-binding lectin A (pMBL-A), and determination of serum concentration heritability. Immunogenetics 2006 0.82
58 CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response. J Immunol 2012 0.82
59 Lung surfactant protein D (SP-D) and the molecular diverted descendants: conglutinin, CL-43 and CL-46. Immunobiology 2002 0.82
60 Evaluation of full-length, cleaved and nitrosylated serum surfactant protein D as biomarkers for COPD. COPD 2011 0.82
61 Pulmonary infections in swine induce altered porcine surfactant protein D expression and localization to dendritic cells in bronchial-associated lymphoid tissue. Immunology 2005 0.82
62 Plasma C3d levels of young farmers correlate with respirable dust exposure levels during normal work in swine confinement buildings. Ann Agric Environ Med 2003 0.80
63 Elevated numbers of SCART1+ gammadelta T cells in skin inflammation and inflammatory bowel disease. Mol Immunol 2010 0.80
64 Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4. PLoS One 2013 0.80
65 CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site. FEBS J 2010 0.80
66 Circulating surfactant protein D is decreased in systemic lupus erythematosus. J Rheumatol 2009 0.80
67 Surfactant protein D (SP-D) deficiency is attenuated in humanised mice expressing the Met(11)Thr short nucleotide polymorphism of SP-D: implications for surfactant metabolism in the lung. J Anat 2013 0.80
68 The presence and activity of SP-D in porcine coronary endothelial cells depend on Akt/PI3K, Erk and nitric oxide and decrease after multiple passaging. Mol Immunol 2008 0.79
69 Cloning and characterization of SCART1, a novel scavenger receptor cysteine-rich type I transmembrane molecule. Mol Immunol 2009 0.78
70 Dynamic strength of the interaction between lung surfactant protein D (SP-D) and saccharide ligands. Biochemistry 2007 0.78
71 Activation of the respiratory burst by Pneumocystis carinii. Efficiency of different antibody isotypes, complement, lung surfactant protein D, and mannan-binding lectin. APMIS 2003 0.78
72 A simple two-step purification procedure for the iC3b binding collectin conglutinin. J Immunol Methods 2010 0.78
73 MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation. Arterioscler Thromb Vasc Biol 2015 0.78
74 Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia. PLoS One 2012 0.77
75 Surfactant protein D is a candidate biomarker for subclinical tobacco smoke-induced lung damage. Am J Physiol Lung Cell Mol Physiol 2014 0.77
76 Genomic and molecular characterization of CL-43 and its proximal promoter. Biochim Biophys Acta 2003 0.77
77 Circulating surfactant protein D is associated to mortality in elderly women: a twin study. Immunobiology 2012 0.77
78 Deleted in malignant brain tumor 1 is secreted in the oviduct and involved in the mechanism of fertilization in equine and porcine species. Reproduction 2013 0.77
79 Crystal structure of the tetrameric fibrinogen-like recognition domain of fibrinogen C domain containing 1 (FIBCD1) protein. J Biol Chem 2013 0.77
80 MFAP4: a candidate biomarker for hepatic and pulmonary fibrosis? Sarcoidosis Vasc Diffuse Lung Dis 2016 0.77
81 Serum surfactant protein D is correlated to development of dementia and augmented mortality. Clin Immunol 2007 0.77
82 Post-neonatal drop in alveolar SP-A expression: biological significance for increased vulnerability to SIDS? Pediatr Pulmonol 2008 0.76
83 Surfactant protein D in atopic dermatitis and psoriasis. Exp Dermatol 2006 0.76
84 Surfactant protein D in newborn infants: factors influencing surfactant protein D levels in umbilical cord blood and capillary blood. Pediatr Res 2005 0.76
85 Monoclonal antibody-assisted structure-function analysis of the carbohydrate recognition domain of surfactant protein D. Am J Physiol Lung Cell Mol Physiol 2010 0.76
86 Identification and characterization of a chitin-binding protein purified from coelomic fluid of the lugworm Arenicola marina defining a novel protein sequence family. J Biol Chem 2012 0.75
87 Genomic and molecular characterization of bovine surfactant protein D (SP-D). Mol Immunol 2004 0.75
88 The pattern recognition molecule deleted in malignant brain tumors 1 (DMBT1) and synthetic mimics inhibit liposomal nucleic acid delivery. Chem Commun (Camb) 2010 0.75
89 Novel characterisation of the gene encoding conglutinin reveals that previously characterised promoter corresponds to the CL-43 promoter. Mol Immunol 2002 0.75
90 Characterization of a novel human scavenger receptor cysteine-rich molecule SCART1 expressed by lymphocytes. Immunobiology 2012 0.75