Christopher N Mayhew

Author PubWeight™ 22.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 2010 5.81
2 Mechanism of hsp70i gene bookmarking. Science 2005 1.96
3 E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis. Mol Cancer Res 2004 1.50
4 RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult. Nucleic Acids Res 2004 1.33
5 Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells. Gastroenterology 2010 1.26
6 HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin. J Biol Chem 2004 1.14
7 Hierarchical requirement of SWI/SNF in retinoblastoma tumor suppressor-mediated repression of Plk1. J Biol Chem 2004 1.11
8 RB loss promotes aberrant ploidy by deregulating levels and activity of DNA replication factors. J Biol Chem 2007 1.10
9 RB reversibly inhibits DNA replication via two temporally distinct mechanisms. Mol Cell Biol 2004 1.01
10 Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control. J Biol Chem 2009 0.97
11 RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage. Gastroenterology 2011 0.97
12 Role of the retinoblastoma tumor suppressor in the maintenance of genome integrity. Curr Mol Med 2006 0.96
13 RB status governs differential sensitivity to cytotoxic and molecularly-targeted therapeutic agents. Cell Cycle 2008 0.95
14 HSF1-TPR interaction facilitates export of stress-induced HSP70 mRNA. J Biol Chem 2007 0.93
15 Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. Toxicology 2008 0.85
16 In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease. Antiviral Res 2004 0.81