Published in Endocr Res on November 01, 2004
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23
Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes. Prostate (2008) 1.06
Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer. Int J Cancer (2010) 0.95
Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels. Cancer Res (2009) 0.90
Steroid hormone synthetic pathways in prostate cancer. Transl Androl Urol (2013) 0.89
Beyond T and DHT - novel steroid derivatives capable of wild type androgen receptor activation. Int J Biol Sci (2014) 0.85
Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors. Prostate (2013) 0.82
The human UGT1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver. J Biol Chem (2009) 0.81
Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression. Horm Cancer (2016) 0.78
Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression. Clin Cancer Res (2016) 0.76
Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines. Cancer Biol Ther (2015) 0.76
Protein kinase Cα and Src kinase support human prostate-distributed dihydrotestosterone-metabolizing UDP-glucuronosyltransferase 2B15 activity. J Biol Chem (2012) 0.75
Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism. Oncotarget (2016) 0.75
UGT2B17 Polymorphism and Risk of Prostate Cancer: A Meta-Analysis. ISRN Oncol (2013) 0.75
Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential. Horm Cancer (2016) 0.75
Screening decreases prostate cancer mortality: 11-year follow-up of the 1988 Quebec prospective randomized controlled trial. Prostate (2004) 4.02
Quantitative trait loci mapping in five new large recombinant inbred line populations of Arabidopsis thaliana genotyped with consensus single-nucleotide polymorphism markers. Genetics (2008) 2.17
Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver. Hepatology (2006) 1.79
Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics. Drug Metab Dispos (2003) 1.72
HLM1, an essential signaling component in the hypersensitive response, is a member of the cyclic nucleotide-gated channel ion channel family. Plant Cell (2003) 1.66
Glucose regulates the expression of the farnesoid X receptor in liver. Diabetes (2004) 1.63
Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation. J Steroid Biochem Mol Biol (2003) 1.61
Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr Rev (2003) 1.60
PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a. J Clin Invest (2005) 1.58
Androgen biosynthetic pathways in the human prostate. Best Pract Res Clin Endocrinol Metab (2008) 1.58
Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression. Gastroenterology (2003) 1.54
Reproducibility of serum sex steroid assays in men by RIA and mass spectrometry. Cancer Epidemiol Biomarkers Prev (2007) 1.53
Prospective evaluation of ursodeoxycholic acid withdrawal in patients with primary sclerosing cholangitis. Hepatology (2014) 1.51
T-DNA integration into the Arabidopsis genome depends on sequences of pre-insertion sites. EMBO Rep (2002) 1.44
The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health? Endocrinology (2003) 1.42
The meiotic protein SWI1 is required for axial element formation and recombination initiation in Arabidopsis. Development (2003) 1.42
Natural variation in Arabidopsis thaliana as a tool for highlighting differential drought responses. PLoS One (2008) 1.33
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans. Trends Endocrinol Metab (2003) 1.31
Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women. J Steroid Biochem Mol Biol (2006) 1.29
Neurosteroid biosynthesis: enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides. Front Neuroendocrinol (2009) 1.26
Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. J Biol Chem (2005) 1.26
Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone. Cancer Res (2006) 1.23
Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes. J Biol Chem (2002) 1.22
The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men. J Clin Endocrinol Metab (2007) 1.19
Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium. J Clin Endocrinol Metab (2004) 1.19
UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells. J Biol Chem (2007) 1.18
A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thaliana. PLoS Genet (2009) 1.16
Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer. J Steroid Biochem Mol Biol (2008) 1.16
Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. PLoS One (2011) 1.15
Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha. J Biol Chem (2002) 1.14
Acute antiinflammatory properties of statins involve peroxisome proliferator-activated receptor-alpha via inhibition of the protein kinase C signaling pathway. Circ Res (2006) 1.13
Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview. Breast Cancer Res (2004) 1.12
Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease. J Biol Chem (2008) 1.11
Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. Drug Metab Dispos (2006) 1.11
Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study. Dig Liver Dis (2011) 1.09
Posterior Malleolar Fractures, a Fracture Not to Be Overlooked: Letter Regarding: Diagnostic Accuracy of 2-Dimensional Computed Tomography for Articular Involvement and Fracture Pattern of Posterior Malleolar Fractures. Foot Ankle Int (2016) 1.09
Gonadotropin-releasing hormone agonists in the treatment of prostate cancer. Endocr Rev (2005) 1.08
Genetic analysis of two Arabidopsis DNA polymerase epsilon subunits during early embryogenesis. Plant J (2005) 1.07
The Arabidopsis MEI1 gene encodes a protein with five BRCT domains that is involved in meiosis-specific DNA repair events independent of SPO11-induced DSBs. Plant J (2003) 1.06
Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. J Steroid Biochem Mol Biol (2008) 1.06
The endosperm and the embryo of Arabidopsis thaliana are independently transformed through infiltration by Agrobacterium tumefaciens. Transgenic Res (2003) 1.05
Urotensin II, from fish to human. Ann N Y Acad Sci (2010) 1.04
Biomarkers of oxidative stress and damage in human populations exposed to arsenic. Mutat Res (2008) 1.03
Biochemical and functional characterization of ORF138, a mitochondrial protein responsible for Ogura cytoplasmic male sterility in Brassiceae. Biochimie (2005) 1.03
Metabolism of DHEA in postmenopausal women following percutaneous administration. J Steroid Biochem Mol Biol (2006) 1.02
The putative Arabidopsis homolog of yeast vps52p is required for pollen tube elongation, localizes to Golgi, and might be involved in vesicle trafficking. Plant Physiol (2004) 1.01
Transcriptomic and metabolomic signatures of an n-3 polyunsaturated fatty acids supplementation in a normolipidemic/normocholesterolemic Caucasian population. J Nutr Biochem (2012) 1.00
Coordinate regulation of hepatic bile acid oxidation and conjugation by nuclear receptors. Mol Pharm (2006) 0.99
Temporary and definitive external fixation of war injuries: use of a French dedicated fixator. Int Orthop (2014) 0.97
Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses. Mol Pharm (2006) 0.97
Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase. J Steroid Biochem Mol Biol (2005) 0.96
Breakage of a volar locking plate after delayed union of a distal radius fracture. Acta Orthop Belg (2007) 0.95
Profiling of endogenous estrogens, their precursors, and metabolites in endometrial cancer patients: association with risk and relationship to clinical characteristics. J Clin Endocrinol Metab (2010) 0.93
Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue. Mol Pharmacol (2005) 0.93
Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate. Best Pract Res Clin Endocrinol Metab (2008) 0.93
The functional UGT1A1 promoter polymorphism decreases endometrial cancer risk. Cancer Res (2004) 0.92
The first zygotic division in Arabidopsis requires de novo transcription of thymidylate kinase. Plant J (2007) 0.92
Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways. J Clin Endocrinol Metab (2010) 0.91
Immunocytochemical localization of sex steroid hormone receptors in normal human mammary gland. J Histochem Cytochem (2009) 0.90
Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans. J Pathol (2010) 0.90
Are women with Sjögren's syndrome androgen-deficient? J Rheumatol (2003) 0.89
Tactile roughness discrimination of the finger pad relies primarily on vibration sensitive afferents not necessarily located in the hand. Behav Brain Res (2012) 0.89
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). Proc Natl Acad Sci U S A (2013) 0.88
Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT. Drug Metab Rev (2013) 0.88
A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3. Pharmacogenet Genomics (2007) 0.88
Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). J Clin Endocrinol Metab (2007) 0.87
The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice. Hepatology (2006) 0.87
Tactile roughness discrimination threshold is unrelated to tactile spatial acuity. Behav Brain Res (2009) 0.87
The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation. Drug Metab Dispos (2013) 0.87
TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone. Mol Cell Biol (2006) 0.86
Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. Endocrinology (2006) 0.86
Vascularized osteochondral graft from the medial femoral trochlea: anatomical study and clinical perspectives. Surg Radiol Anat (2010) 0.86
Gliotransmission and brain glucose sensing: critical role of endozepines. Diabetes (2012) 0.86
Differences in metabolomic and transcriptomic profiles between responders and non-responders to an n-3 polyunsaturated fatty acids (PUFAs) supplementation. Genes Nutr (2012) 0.86
Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression. J Clin Endocrinol Metab (2011) 0.85
Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential. Drug Metab Rev (2010) 0.85
Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells. Mol Cancer Ther (2008) 0.85
DOMINO1, a member of a small plant-specific gene family, encodes a protein essential for nuclear and nucleolar functions. Plant J (2004) 0.85
Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium. Can J Physiol Pharmacol (2003) 0.83
QQT proteins colocalize with microtubules and are essential for early embryo development in Arabidopsis. Plant J (2007) 0.83
Flanking sequence tags in Arabidopsis thaliana T-DNA insertion lines: a pilot study. C R Biol (2002) 0.83
Immunohistochemical localization and biological activity of 3beta-hydroxysteroid dehydrogenase and 5alpha-reductase in the brain of the frog, Rana esculenta, during development. J Chem Neuroanat (2010) 0.83
Immunohistochemical localization and biological activity of the steroidogenic enzyme cytochrome P450 17alpha-hydroxylase/C17, 20-lyase (P450C17) in the frog brain and pituitary. J Neurochem (2006) 0.83
Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells. Biochem J (2008) 0.82
Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization. Cell Signal (2011) 0.82