1
|
Breast-cancer risk in families with mutations in PALB2.
|
N Engl J Med
|
2014
|
4.97
|
2
|
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.
|
Nat Genet
|
2010
|
4.96
|
3
|
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
|
Nat Genet
|
2013
|
4.35
|
4
|
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.
|
Nat Genet
|
2011
|
3.37
|
5
|
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
|
PLoS Genet
|
2013
|
2.39
|
6
|
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
|
Am J Hum Genet
|
2013
|
2.24
|
7
|
19p13.1 is a triple-negative-specific breast cancer susceptibility locus.
|
Cancer Res
|
2012
|
1.81
|
8
|
Common breast cancer susceptibility loci are associated with triple-negative breast cancer.
|
Cancer Res
|
2011
|
1.65
|
9
|
Growth index is independent of microvessel density in non-small-cell lung carcinomas.
|
Hum Pathol
|
2002
|
1.53
|
10
|
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.
|
Carcinogenesis
|
2013
|
1.28
|
11
|
On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations.
|
Eur J Hum Genet
|
2010
|
1.17
|
12
|
Prevalence of GJB2 mutations in prelingual deafness in the Greek population.
|
Int J Pediatr Otorhinolaryngol
|
2002
|
1.06
|
13
|
Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: implications for genetic screening selection criteria: a Hellenic Cooperative Oncology Group Study.
|
Breast Cancer Res Treat
|
2012
|
1.01
|
14
|
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.
|
Hum Mol Genet
|
2013
|
1.00
|
15
|
Collaborative genomics for human health and cooperation in the Mediterranean region.
|
Nat Genet
|
2010
|
0.99
|
16
|
G1738R is a BRCA1 founder mutation in Greek breast/ovarian cancer patients: evaluation of its pathogenicity and inferences on its genealogical history.
|
Breast Cancer Res Treat
|
2007
|
0.97
|
17
|
A newly detected mutation of the RET protooncogene in exon 8 as a cause of multiple endocrine neoplasia type 2A.
|
Hormones (Athens)
|
2007
|
0.96
|
18
|
Greek BRCA1 and BRCA2 mutation spectrum: two BRCA1 mutations account for half the carriers found among high-risk breast/ovarian cancer patients.
|
Breast Cancer Res Treat
|
2007
|
0.94
|
19
|
Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene.
|
Int J Cancer
|
2005
|
0.91
|
20
|
International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation.
|
Breast Cancer Res Treat
|
2010
|
0.91
|
21
|
Novel genomic rearrangements in the BRCA1 gene detected in Greek breast/ovarian cancer patients.
|
Eur J Cancer
|
2006
|
0.90
|
22
|
Characterization of a novel large deletion and single point mutations in the BRCA1 gene in a Greek cohort of families with suspected hereditary breast cancer.
|
BMC Cancer
|
2004
|
0.88
|
23
|
Thermal unfolding of human BRCA1 BRCT-domain variants.
|
Biochim Biophys Acta
|
2007
|
0.86
|
24
|
Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
0.86
|
25
|
BRCA2 gene mutations in Greek patients with familial breast cancer.
|
Hum Mutat
|
2002
|
0.86
|
26
|
Evaluation of dHPLC in mutation screening of the APC gene in a Greek FAP cohort.
|
Anticancer Res
|
2003
|
0.85
|
27
|
Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients.
|
BMC Cancer
|
2010
|
0.85
|
28
|
A distinct mutation on the alternative splice site of APC exon 9 results in attenuated familial adenomatous polyposis phenotype.
|
Fam Cancer
|
2010
|
0.82
|
29
|
A rare RET gene exon 8 mutation is found in two Greek kindreds with familial medullary thyroid carcinoma: implications for screening.
|
Clin Endocrinol (Oxf)
|
2006
|
0.80
|
30
|
Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cases.
|
PLoS One
|
2013
|
0.80
|
31
|
BRCA1 wild-type allele modifies risk of ovarian cancer in carriers of BRCA1 germ-line mutations.
|
Cancer Epidemiol Biomarkers Prev
|
2003
|
0.79
|
32
|
Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide.
|
Biochim Biophys Acta
|
2010
|
0.79
|
33
|
Fully integrated monolithic optoelectronic transducer for real-time protein and DNA detection: the NEMOSLAB approach.
|
Biosens Bioelectron
|
2010
|
0.78
|
34
|
Hereditary cancer syndromes.
|
J BUON
|
2007
|
0.78
|
35
|
Atypical medullary breast carcinoma in a family carrying the 5382insC BRCA-1 mutation.
|
Breast J
|
2003
|
0.77
|
36
|
Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families.
|
BMC Cancer
|
2010
|
0.77
|
37
|
Lack of association between RNASEL Arg462Gln variant and the risk of breast cancer.
|
Anticancer Res
|
2004
|
0.77
|
38
|
Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1.
|
Biophys Chem
|
2004
|
0.76
|
39
|
A change in the last base of BRCA1 exon 23, 5586G-->A, results in abnormal RNA splicing.
|
Cancer Genet Cytogenet
|
2002
|
0.75
|
40
|
An in-frame exon-skipping MUTYH mutation is associated with early-onset colorectal cancer.
|
Dis Colon Rectum
|
2010
|
0.75
|
41
|
Culture of primary epithelial adenoma cells from familial adenomatous polyposis patients.
|
Anticancer Res
|
2008
|
0.75
|