1
|
SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts.
|
Leukemia
|
2011
|
2.82
|
2
|
Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo.
|
Blood
|
2000
|
2.42
|
3
|
Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies.
|
Leukemia
|
2010
|
2.01
|
4
|
Telomere length in leukocyte subpopulations of patients with aplastic anemia.
|
Blood
|
2001
|
1.89
|
5
|
Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.
|
Leukemia
|
2013
|
1.84
|
6
|
Correction of the PNH defect by GPI-anchored protein transfer.
|
Blood
|
1998
|
1.55
|
7
|
UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation.
|
Leukemia
|
2008
|
1.39
|
8
|
Clonality of the stem cell compartment during evolution of myelodysplastic syndromes and other bone marrow failure syndromes.
|
Leukemia
|
2007
|
1.37
|
9
|
Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death.
|
J Cell Physiol
|
1995
|
1.33
|
10
|
Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition.
|
Blood
|
1996
|
1.32
|
11
|
Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders.
|
Leukemia
|
2012
|
1.31
|
12
|
Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication.
|
Blood
|
1997
|
1.26
|
13
|
Limited heterogeneity of T cell receptor BV usage in aplastic anemia.
|
J Clin Invest
|
2001
|
1.25
|
14
|
Spread of human cytomegalovirus (HCMV) after infection of human hematopoietic progenitor cells: model of HCMV latency.
|
Blood
|
1997
|
1.24
|
15
|
TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p.
|
Leukemia
|
2009
|
1.23
|
16
|
Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures.
|
Blood
|
1998
|
1.19
|
17
|
Single nucleotide polymorphism arrays complement metaphase cytogenetics in detection of new chromosomal lesions in MDS.
|
Leukemia
|
2007
|
1.19
|
18
|
Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion.
|
Oncogene
|
2012
|
1.16
|
19
|
Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies.
|
Leukemia
|
2013
|
1.10
|
20
|
Involvement of Fas-mediated apoptosis in the inhibitory effects of interferon-alpha in chronic myelogenous leukemia.
|
Blood
|
1997
|
1.04
|
21
|
Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3.
|
Blood
|
1997
|
1.03
|
22
|
Paroxysmal nocturnal hemoglobinuria and concurrent JAK2(V617F) mutation.
|
Blood Cancer J
|
2012
|
1.02
|
23
|
Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia.
|
Exp Hematol
|
2001
|
1.02
|
24
|
Induction of nitric oxide synthase is involved in the mechanism of Fas-mediated apoptosis in haemopoietic cells.
|
Br J Haematol
|
1997
|
0.98
|
25
|
Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells.
|
Leukemia
|
2005
|
0.98
|
26
|
Expression and modulation of cellular receptors for interferon-gamma, tumour necrosis factor, and Fas on human bone marrow CD34+ cells.
|
Br J Haematol
|
1997
|
0.97
|
27
|
Deletions of Xp22.2 including PIG-A locus lead to paroxysmal nocturnal hemoglobinuria.
|
Leukemia
|
2010
|
0.96
|
28
|
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation.
|
Blood Cancer J
|
2013
|
0.93
|
29
|
Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients.
|
Leukemia
|
2005
|
0.92
|
30
|
Secondary colony formation after long-term bone marrow culture using peripheral blood and bone marrow of HIV-infected patients.
|
AIDS
|
1997
|
0.91
|
31
|
Survival of AML patients receiving HLA-matched sibling donor allogeneic bone marrow transplantation correlates with HLA-Cw ligand groups for killer immunoglobulin-like receptors.
|
Bone Marrow Transplant
|
2007
|
0.90
|
32
|
CBL mutation-related patterns of phosphorylation and sensitivity to tyrosine kinase inhibitors.
|
Leukemia
|
2012
|
0.88
|
33
|
Double-negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation.
|
Br J Haematol
|
2008
|
0.88
|
34
|
In vitro infection of megakaryocytes and their precursors by human cytomegalovirus.
|
Blood
|
2000
|
0.87
|
35
|
Cytomegalovirus-specific regulatory and effector T cells share TCR clonality--possible relation to repetitive CMV infections.
|
Am J Transplant
|
2011
|
0.87
|
36
|
Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?".
|
J Clin Invest
|
2000
|
0.86
|
37
|
Apoptosis induced by human cytomegalovirus infection can be enhanced by cytokines to limit the spread of virus.
|
Exp Hematol
|
1999
|
0.84
|
38
|
Influence of killer immunoglobulin-like receptor/HLA ligand matching on achievement of T-cell complete donor chimerism in related donor nonmyeloablative allogeneic hematopoietic stem cell transplantation.
|
Bone Marrow Transplant
|
2008
|
0.84
|
39
|
Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome.
|
Leukemia
|
2007
|
0.84
|
40
|
Hypocupremia and bone marrow failure.
|
Haematologica
|
2008
|
0.83
|
41
|
Hematopoietic inhibition by interferon-gamma is partially mediated through interferon regulatory factor-1.
|
Blood
|
1995
|
0.82
|
42
|
Impact of immunogenetic polymorphisms in bone marrow failure syndromes.
|
Mini Rev Med Chem
|
2011
|
0.82
|
43
|
Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndrome.
|
Leukemia
|
1998
|
0.82
|
44
|
The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection.
|
J Clin Invest
|
1998
|
0.82
|
45
|
Fas-mediated modulation of Bcr/Abl in chronic myelogenous leukemia results in differential effects on apoptosis.
|
Blood
|
1998
|
0.81
|
46
|
Inhibition of interleukin-1beta-converting enzyme in human hematopoietic progenitor cells results in blockade of cytokine-mediated apoptosis and expansion of their proliferative potential.
|
Exp Hematol
|
1998
|
0.81
|
47
|
Long-lasting decrease of marrow and circulating long-term culture initiating cells after allogeneic bone marrow transplant.
|
Bone Marrow Transplant
|
1999
|
0.80
|
48
|
Constitution and telomere dynamics of bone marrow stromal cells in patients undergoing allogeneic bone marrow transplantation.
|
Bone Marrow Transplant
|
2003
|
0.79
|
49
|
The role of FAS-mediated apoptosis in chronic myelogenous leukemia.
|
Leuk Lymphoma
|
2000
|
0.77
|
50
|
Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
|
Leukemia
|
2013
|
0.77
|
51
|
Nitric oxide and cell survival: megakaryocytes say "NO".
|
J Lab Clin Med
|
2001
|
0.76
|
52
|
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.
|
Leukemia
|
2015
|
0.76
|
53
|
CSF3R T618I co-occurs with mutations of splicing and epigenetic genes and with a new PIM3 truncated fusion gene in chronic neutrophilic leukemia.
|
Blood Cancer J
|
2013
|
0.76
|
54
|
Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome.
|
Leukemia
|
2017
|
0.75
|
55
|
Epidemiology and risk factors for infections in myelodysplastic syndromes.
|
Transpl Infect Dis
|
2013
|
0.75
|