Published in Radiology on February 01, 2005
Ultrasound mediated delivery of drugs and genes to solid tumors. Adv Drug Deliv Rev (2008) 1.93
High intensity focused ultrasound in clinical tumor ablation. World J Clin Oncol (2011) 1.55
Magnetic resonance-guided focused ultrasound surgery: Part 2: A review of current and future applications. Neurosurgery (2012) 1.53
Pulsed high-intensity focused ultrasound enhances thrombolysis in an in vitro model. Radiology (2006) 1.51
Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study. Thromb Res (2007) 1.21
Phase-shift, stimuli-responsive perfluorocarbon nanodroplets for drug delivery to cancer. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2012) 1.18
Pulsed high intensity focused ultrasound mediated nanoparticle delivery: mechanisms and efficacy in murine muscle. Ultrasound Med Biol (2008) 1.18
Ultrasound-triggered release of materials entrapped in microbubble-liposome constructs: a tool for targeted drug delivery. J Control Release (2010) 1.06
Focused ultrasound and microbubbles for enhanced extravasation. J Control Release (2010) 1.03
In vitro and in vivo evaluations of increased effective beam width for heat deposition using a split focus high intensity ultrasound (HIFU) transducer. Int J Hyperthermia (2008) 0.99
Current and Future Clinical Applications of High-Intensity Focused Ultrasound (HIFU) for Pancreatic Cancer. Gut Liver (2010) 0.96
Changes in cell morphology due to plasma membrane wounding by acoustic cavitation. Ultrasound Med Biol (2010) 0.95
Pulsed ultrasound enhances nanoparticle penetration into breast cancer spheroids. Mol Pharm (2010) 0.94
Comparison of continuous vs. pulsed focused ultrasound in treated muscle tissue as evaluated by magnetic resonance imaging, histological analysis, and microarray analysis. Eur Radiol (2008) 0.92
Phase-shift, stimuli-responsive drug carriers for targeted delivery. Ther Deliv (2011) 0.90
Pharmacokinetic analysis of 111 in-labeled liposomal Doxorubicin in murine glioblastoma after blood-brain barrier disruption by focused ultrasound. PLoS One (2012) 0.89
Ultrasonic enhancement of drug penetration in solid tumors. Front Oncol (2013) 0.83
MRI-based prediction of pulsed high-intensity focused ultrasound effect on tissue transport in rabbit muscle. J Magn Reson Imaging (2013) 0.83
Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer. Cancer Res (2015) 0.82
Realtime control of multiple-focus phased array heating patterns based on noninvasive ultrasound thermography. IEEE Trans Biomed Eng (2011) 0.82
Nanotechnology for energy-based cancer therapies. Am J Cancer Res (2011) 0.81
MR-guided pulsed high intensity focused ultrasound enhancement of docetaxel combined with radiotherapy for prostate cancer treatment. Phys Med Biol (2012) 0.80
An alternating focused ultrasound system for thermal therapy studies in small animals. Med Phys (2011) 0.79
Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models. J Clin Invest (2015) 0.79
Emerging local ablation techniques. Semin Intervent Radiol (2006) 0.78
Sequential HIFU heating and nanobubble encapsulation provide efficient drug penetration from stealth and temperature sensitive liposomes in colon cancer. J Control Release (2016) 0.77
An in-vivo investigation of the therapeutic effect of pulsed focused ultrasound on tumor growth. Med Phys (2014) 0.75
Distribution of doxorubicin in rats undergoing ultrasonic drug delivery. J Pharm Sci (2010) 0.75
Theragnostic ultrasound using microbubbles in the treatment of prostate cancer. Ultrasonography (2016) 0.75
Cancer treatment using an optically inert Rose Bengal derivative combined with pulsed focused ultrasound. J Control Release (2011) 0.75
Portable high-intensity focused ultrasound system with 3D electronic steering, real-time cavitation monitoring, and 3D image reconstruction algorithms: a preclinical study in pigs. Ultrasonography (2014) 0.75
A draft sequence of the rice genome (Oryza sativa L. ssp. japonica). Science (2002) 21.26
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
Pulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effect. Clin Cancer Res (2007) 2.17
Signal transducer and activator of transcription-5 activation and breast cancer prognosis. J Clin Oncol (2004) 2.04
Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice. J Immunol (2009) 2.03
Radiofrequency ablation induces antigen-presenting cell infiltration and amplification of weak tumor-induced immunity. Radiology (2009) 1.95
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect Immun (2007) 1.85
Pulsed high-intensity focused ultrasound enhances apoptosis and growth inhibition of squamous cell carcinoma xenografts with proteasome inhibitor bortezomib. Radiology (2008) 1.82
Gene families encoding transcription factors expressed in early development of Strongylocentrotus purpuratus. Dev Biol (2006) 1.77
Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. Oncogene (2005) 1.76
Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice. J Exp Med (2014) 1.76
Magnetic resonance image-guided proteomics of human glioblastoma multiforme. J Magn Reson Imaging (2003) 1.69
High genetic diversity of HIV-1 was found in men who have sex with men in Shijiazhuang, China. Infect Genet Evol (2011) 1.65
Magnetic resonance imaging and confocal microscopy studies of magnetically labeled endothelial progenitor cells trafficking to sites of tumor angiogenesis. Stem Cells (2005) 1.61
Identification and characterization of homeobox transcription factor genes in Strongylocentrotus purpuratus, and their expression in embryonic development. Dev Biol (2006) 1.60
Delivery of liposomal doxorubicin (Doxil) in a breast cancer tumor model: investigation of potential enhancement by pulsed-high intensity focused ultrasound exposure. Acad Radiol (2006) 1.60
Intramembrane cavitation as a unifying mechanism for ultrasound-induced bioeffects. Proc Natl Acad Sci U S A (2011) 1.58
Molecular imaging applications in nanomedicine. Biomed Microdevices (2004) 1.54
Pulsed high-intensity focused ultrasound enhances thrombolysis in an in vitro model. Radiology (2006) 1.51
Investigations into pulsed high-intensity focused ultrasound-enhanced delivery: preliminary evidence for a novel mechanism. Ultrasound Med Biol (2009) 1.51
A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue. Diagn Mol Pathol (2009) 1.50
Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model. J Control Release (2011) 1.49
Association of metformin use with cancer incidence and mortality: a meta-analysis. Cancer Epidemiol (2013) 1.49
Activation of signal transducer and activator of transcription 5 in human prostate cancer is associated with high histological grade. Cancer Res (2004) 1.47
Pulsed high-intensity focused ultrasound enhances systemic administration of naked DNA in squamous cell carcinoma model: initial experience. Radiology (2005) 1.46
Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. Cardiovasc Diabetol (2011) 1.45
Recombination form and epidemiology of HIV-1 unique recombinant strains identified in Yunnan, China. PLoS One (2012) 1.43
Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells. J Biol Chem (2003) 1.43
A primer on molecular biology for imagers: I. DNA, how does it work? Acad Radiol (2003) 1.39
Angiogenesis is required for successful bone induction during distraction osteogenesis. J Bone Miner Res (2005) 1.36
Potential role of pulsed-high intensity focused ultrasound in gene therapy. Future Oncol (2006) 1.29
Genetic characterization of 13 subtype CRF01_AE near full-length genomes in Guangxi, China. AIDS Res Hum Retroviruses (2010) 1.27
Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections. BMC Microbiol (2006) 1.27
Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium. Mol Endocrinol (2002) 1.22
Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells. J Biol Chem (2003) 1.22
Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study. Thromb Res (2007) 1.21
Pulsed high-intensity focused ultrasound enhances uptake of radiolabeled monoclonal antibody to human epidermoid tumor in nude mice. J Nucl Med (2008) 1.20
RRM1 expression and clinical outcome of gemcitabine-containing chemotherapy for advanced non-small-cell lung cancer: a meta-analysis. Lung Cancer (2011) 1.20
Pulsed high intensity focused ultrasound mediated nanoparticle delivery: mechanisms and efficacy in murine muscle. Ultrasound Med Biol (2008) 1.18
Bidirectional modulation of GABA release by presynaptic glutamate receptor 5 kainate receptors in the basolateral amygdala. J Neurosci (2003) 1.16
Demographic and clinical characteristics of patients with anaphylactic shock after surgery for cystic echinococcosis. Am J Trop Med Hyg (2011) 1.15
A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles. Int J Radiat Oncol Biol Phys (2004) 1.12
Synthesis, in vitro, and in vivo characterization of an integrin alpha(v)beta(3)-targeted molecular probe for optical imaging of tumor. Bioorg Med Chem (2005) 1.11
Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance. J Neurosci (2013) 1.10
Synergy of human immunodeficiency virus protease inhibitors with chloroquine against Plasmodium falciparum in vitro and Plasmodium chabaudi in vivo. Antimicrob Agents Chemother (2008) 1.09
Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum. J Biol Chem (2006) 1.09
Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. Mol Endocrinol (2007) 1.09
One scorpion, two venoms: prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proc Natl Acad Sci U S A (2003) 1.09
Subtype CRF01_AE dominate the sexually transmitted human immunodeficiency virus type 1 epidemic in Guangxi, China. J Med Virol (2013) 1.06
Transcriptome profiling of testis during sexual maturation stages in Eriocheir sinensis using Illumina sequencing. PLoS One (2012) 1.04
Presence of EGF growth factor ligands and their effects on cultured rat conjunctival goblet cell proliferation. Exp Eye Res (2007) 1.03
Identification and characterization of two new HIV type 1 Unique (B/C) recombinant forms in China. AIDS Res Hum Retroviruses (2010) 1.01
Enhanced homing permeability and retention of bone marrow stromal cells by noninvasive pulsed focused ultrasound. Stem Cells (2012) 1.00
Multiple introductions of HIV into men who have sex with men were found in Zhengzhou City, China. AIDS Res Hum Retroviruses (2012) 1.00
Microarray gene expression analysis of murine tumor heterogeneity defined by dynamic contrast-enhanced MRI. Mol Imaging (2002) 1.00
In vitro and in vivo evaluations of increased effective beam width for heat deposition using a split focus high intensity ultrasound (HIFU) transducer. Int J Hyperthermia (2008) 0.99
Vascular-targeted molecular imaging using functionalized polymerized vesicles. J Magn Reson Imaging (2002) 0.98
Biomaterial selection for tooth regeneration. Tissue Eng Part B Rev (2011) 0.98
Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori. FEBS J (2006) 0.98
Monte Carlo based IMRT dose verification using MLC log files and R/V outputs. Med Phys (2006) 0.98
Gadolinium-rhodamine nanoparticles for cell labeling and tracking via magnetic resonance and optical imaging. Bioconjug Chem (2005) 0.97
Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer. Mol Cancer (2005) 0.97
Danshen extract 15,16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways. J Steroid Biochem Mol Biol (2010) 0.97
Genetic characterization and transmitted drug resistance of the HIV type 1 epidemic in men who have sex with men in Beijing, China. AIDS Res Hum Retroviruses (2013) 0.96
MRI-guided thermal ablation therapy: model and parameter estimates to predict cell death from MR thermometry images. Ann Biomed Eng (2007) 0.95
Binding analyses between Human PPARgamma-LBD and ligands. Eur J Biochem (2004) 0.95
Protein phosphatase-1 modulates the function of Pax-6, a transcription factor controlling brain and eye development. J Biol Chem (2007) 0.95
A review: Integrin alphavbeta3-targeted molecular imaging and therapy in angiogenesis. Nanomedicine (2005) 0.93
Molecular determinants of magnolol targeting both RXRα and PPARγ. PLoS One (2011) 0.93
Epithelial-mesenchymal interactions as a working concept for oral mucosa regeneration. Tissue Eng Part B Rev (2011) 0.93
Recent increases in efficiency in cigarette nicotine delivery: implications for tobacco control. Nicotine Tob Res (2014) 0.93
Lipocalin-2, glucose metabolism and chronic low-grade systemic inflammation in Chinese people. Cardiovasc Diabetol (2012) 0.92
Identification of novel falcipain-2 inhibitors as potential antimalarial agents through structure-based virtual screening. J Med Chem (2009) 0.92
MPIC: a high-throughput analytical method for multiple DNA targets. Anal Chem (2011) 0.92
Liquorice, a unique "guide drug" of traditional Chinese medicine: a review of its role in drug interactions. J Ethnopharmacol (2013) 0.92
Comparison of continuous vs. pulsed focused ultrasound in treated muscle tissue as evaluated by magnetic resonance imaging, histological analysis, and microarray analysis. Eur Radiol (2008) 0.92
Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J Biol Chem (2010) 0.91
Retracted Effects of adipose stem cell-conditioned medium on the migration of vascular endothelial cells, fibroblasts and keratinocytes. Exp Ther Med (2013) 0.91
Effects of baicalein on Sendai virus in vivo are linked to serum baicalin and its inhibition of hemagglutinin-neuraminidase. Arch Virol (2011) 0.91
Seroprevalence of HIV, syphilis, and hepatitis C virus in the general population of the Liangshan Prefecture, Sichuan Province, China. J Med Virol (2011) 0.90
Side-by-side comparison of the biological characteristics of human umbilical cord and adipose tissue-derived mesenchymal stem cells. Biomed Res Int (2013) 0.90
Mechanic effect of pulsed focused ultrasound in tumor and muscle tissue evaluated by MRI, histology, and microarray analysis. Eur J Radiol (2009) 0.89
Analytical Validation of a Highly Quantitative, Sensitive, Accurate, and Reproducible Assay (HERmark) for the Measurement of HER2 Total Protein and HER2 Homodimers in FFPE Breast Cancer Tumor Specimens. Patholog Res Int (2010) 0.89
Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors. J Med Chem (2010) 0.89
Vascular-targeted nanoparticles for molecular imaging and therapy. Methods Enzymol (2004) 0.89
Synthesis and evaluation of a near-infrared fluorescent non-peptidic bivalent integrin alpha(v)beta(3) antagonist for cancer imaging. Bioconjug Chem (2010) 0.89
Uncertainties in IMRT dosimetry. Med Phys (2010) 0.89