1
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Synthetic mammalian prions.
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Science
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2004
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7.35
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2
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Recombinant prion protein induces a new transmissible prion disease in wild-type animals.
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Acta Neuropathol
|
2010
|
3.19
|
3
|
In vitro conversion of full-length mammalian prion protein produces amyloid form with physical properties of PrP(Sc).
|
J Mol Biol
|
2004
|
2.59
|
4
|
Design and construction of diverse mammalian prion strains.
|
Proc Natl Acad Sci U S A
|
2009
|
2.41
|
5
|
Strain-specified characteristics of mouse synthetic prions.
|
Proc Natl Acad Sci U S A
|
2005
|
2.25
|
6
|
Protease-sensitive synthetic prions.
|
PLoS Pathog
|
2010
|
2.14
|
7
|
The same primary structure of the prion protein yields two distinct self-propagating states.
|
J Biol Chem
|
2008
|
1.64
|
8
|
Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob Disease.
|
Protein Sci
|
2005
|
1.62
|
9
|
The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance.
|
Biochemistry
|
2010
|
1.53
|
10
|
Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease.
|
PLoS Pathog
|
2011
|
1.53
|
11
|
Amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons.
|
J Biol Chem
|
2006
|
1.47
|
12
|
Highly efficient protein misfolding cyclic amplification.
|
PLoS Pathog
|
2011
|
1.46
|
13
|
Polymorphism and ultrastructural organization of prion protein amyloid fibrils: an insight from high resolution atomic force microscopy.
|
J Mol Biol
|
2006
|
1.44
|
14
|
Annealing prion protein amyloid fibrils at high temperature results in extension of a proteinase K-resistant core.
|
J Biol Chem
|
2005
|
1.44
|
15
|
Conformational switching within individual amyloid fibrils.
|
J Biol Chem
|
2009
|
1.31
|
16
|
Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils.
|
Biochemistry
|
2005
|
1.28
|
17
|
Conformational stability of PrP amyloid fibrils controls their smallest possible fragment size.
|
J Mol Biol
|
2008
|
1.27
|
18
|
A new mechanism for transmissible prion diseases.
|
J Neurosci
|
2012
|
1.25
|
19
|
Methionine oxidation interferes with conversion of the prion protein into the fibrillar proteinase K-resistant conformation.
|
Biochemistry
|
2005
|
1.25
|
20
|
Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay.
|
J Biol Chem
|
2006
|
1.22
|
21
|
Two amyloid States of the prion protein display significantly different folding patterns.
|
J Mol Biol
|
2010
|
1.16
|
22
|
Site-specific conformational studies of prion protein (PrP) amyloid fibrils revealed two cooperative folding domains within amyloid structure.
|
J Biol Chem
|
2007
|
1.14
|
23
|
Stabilization of a prion strain of synthetic origin requires multiple serial passages.
|
J Biol Chem
|
2012
|
1.13
|
24
|
Highly promiscuous nature of prion polymerization.
|
J Biol Chem
|
2007
|
1.12
|
25
|
Relationship between conformational stability and amplification efficiency of prions.
|
Biochemistry
|
2011
|
1.11
|
26
|
Chemoenzymatic synthesis of HIV-1 V3 glycopeptides carrying two N-glycans and effects of glycosylation on the peptide domain.
|
J Org Chem
|
2005
|
1.06
|
27
|
Dichotomous versus palm-type mechanisms of lateral assembly of amyloid fibrils.
|
Protein Sci
|
2006
|
1.04
|
28
|
Fast and ultrasensitive method for quantitating prion infectivity titre.
|
Nat Commun
|
2012
|
1.01
|
29
|
The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.
|
J Mol Biol
|
2008
|
1.01
|
30
|
Changes in prion replication environment cause prion strain mutation.
|
FASEB J
|
2013
|
0.99
|
31
|
Methods for conversion of prion protein into amyloid fibrils.
|
Methods Mol Biol
|
2008
|
0.98
|
32
|
Light-dependent electrogenic activity of cyanobacteria.
|
PLoS One
|
2010
|
0.98
|
33
|
Expression and purification of full-length recombinant PrP of high purity.
|
Methods Mol Biol
|
2008
|
0.97
|
34
|
The dominant-negative effect of the Q218K variant of the prion protein does not require protein X.
|
Protein Sci
|
2007
|
0.96
|
35
|
Selective amplification of classical and atypical prions using modified protein misfolding cyclic amplification.
|
J Biol Chem
|
2012
|
0.96
|
36
|
Assessment of strain-specific PrP(Sc) elongation rates revealed a transformation of PrP(Sc) properties during protein misfolding cyclic amplification.
|
PLoS One
|
2012
|
0.95
|
37
|
Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4.
|
J Cell Sci
|
2010
|
0.94
|
38
|
The evolution of transmissible prions: the role of deformed templating.
|
PLoS Pathog
|
2013
|
0.91
|
39
|
The cellular form of the prion protein is involved in controlling cell cycle dynamics, self-renewal, and the fate of human embryonic stem cell differentiation.
|
J Neurochem
|
2012
|
0.89
|
40
|
Nonpolar substitution at the C-terminus of the prion protein, a mimic of the glycosylphosphatidylinositol anchor, partially impairs amyloid fibril formation.
|
Biochemistry
|
2007
|
0.89
|
41
|
Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity.
|
PLoS One
|
2011
|
0.89
|
42
|
Oligomeric-induced activity by thienyl pyrimidine compounds traps prion infectivity.
|
J Neurosci
|
2011
|
0.88
|
43
|
Hemicentin assembly in the extracellular matrix is mediated by distinct structural modules.
|
J Biol Chem
|
2006
|
0.88
|
44
|
Dissecting structure of prion amyloid fibrils by hydrogen-deuterium exchange ultraviolet Raman spectroscopy.
|
J Phys Chem B
|
2012
|
0.87
|
45
|
Treatment with normal prion protein delays differentiation and helps to maintain high proliferation activity in human embryonic stem cells.
|
J Neurochem
|
2010
|
0.87
|
46
|
Amyloid features and neuronal toxicity of mature prion fibrils are highly sensitive to high pressure.
|
J Biol Chem
|
2011
|
0.85
|
47
|
Amyloid fibrils of mammalian prion protein induce axonal degeneration in NTERA2-derived terminally differentiated neurons.
|
J Neurochem
|
2007
|
0.84
|
48
|
Genesis of tramsmissible protein states via deformed templating.
|
Prion
|
2012
|
0.84
|
49
|
Photosynthetic microbial fuel cells with positive light response.
|
Biotechnol Bioeng
|
2009
|
0.83
|
50
|
Role of the photosynthetic electron transfer chain in electrogenic activity of cyanobacteria.
|
Appl Microbiol Biotechnol
|
2011
|
0.82
|
51
|
Semiautomated cell-free conversion of prion protein: applications for high-throughput screening of potential antiprion drugs.
|
Anal Biochem
|
2005
|
0.82
|
52
|
Water-soluble hybrid nanoclusters with extra bright and photostable emissions: a new tool for biological imaging.
|
Biophys J
|
2005
|
0.81
|
53
|
Synthesis, conformation, and immunogenicity of monosaccharide-centered multivalent HIV-1 gp41 peptides containing the sequence of DP178.
|
Bioorg Med Chem
|
2004
|
0.81
|
54
|
The cellular form of the prion protein guides the differentiation of human embryonic stem cells into neuron-, oligodendrocyte-, and astrocyte-committed lineages.
|
Prion
|
2014
|
0.80
|
55
|
Atypical and classical forms of the disease-associated state of the prion protein exhibit distinct neuronal tropism, deposition patterns, and lesion profiles.
|
Am J Pathol
|
2013
|
0.79
|
56
|
Ubiquitination-induced fluorescence complementation (UiFC) for detection of K48 ubiquitin chains in vitro and in live cells.
|
PLoS One
|
2013
|
0.79
|
57
|
Nanostructured polypyrrole-coated anode for sun-powered microbial fuel cells.
|
Bioelectrochemistry
|
2009
|
0.78
|
58
|
Atomic force fluorescence microscopy in the characterization of amyloid fibril assembly and oligomeric intermediates.
|
Methods Mol Biol
|
2012
|
0.77
|
59
|
Purification and fibrillation of full-length recombinant PrP.
|
Methods Mol Biol
|
2012
|
0.76
|