R C Koehler

Author PubWeight™ 109.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Heme oxygenase-2 is neuroprotective in cerebral ischemia. Mol Med 1999 1.70
2 Production and characteristics of an infusible oxygen-carrying fluid based on hemoglobin intramolecularly cross-linked with sebacic acid. J Lab Clin Med 1996 1.64
3 Effect of arrest time and cerebral perfusion pressure during cardiopulmonary resuscitation on cerebral blood flow, metabolism, adenosine triphosphate recovery, and pH in dogs. Crit Care Med 1999 1.48
4 Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J Appl Physiol (1985) 1991 1.48
5 Effect of nitric oxide synthase inhibition on cerebral blood flow and injury volume during focal ischemia in cats. Stroke 1993 1.42
6 Interaction of fentanyl and pentobarbital on peripheral and cerebral hemodynamics in newborn lambs. Anesthesiology 1989 1.39
7 Primary sensory and forebrain motor systems in the newborn brain are preferentially damaged by hypoxia-ischemia. J Comp Neurol 1997 1.33
8 Mechanisms by which epinephrine augments cerebral and myocardial perfusion during cardiopulmonary resuscitation in dogs. Circulation 1984 1.25
9 Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia. Neuroscience 2000 1.19
10 A compartmental model for oxygen transport in brain microcirculation. Ann Biomed Eng 1989 1.16
11 Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat. Neuroscience 1996 1.15
12 Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats. Am J Physiol 1991 1.13
13 Influence of CO2 on cardiovascular response to hypoxia in conscious dogs. Am J Physiol 1980 1.07
14 Regional blood flow alterations after bovine fumaryl beta beta-crosslinked hemoglobin transfusion and nitric oxide synthase inhibition. Crit Care Med 1996 1.04
15 Cerebrovascular autoregulation during fetal development in sheep. Am J Physiol 1994 1.02
16 Potent sigma1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine modulates basal and N-methyl-D-aspartate-evoked nitric oxide production in vivo. Stroke 1998 0.98
17 P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate. Am J Physiol Heart Circ Physiol 2000 0.98
18 Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus. Neuroscience 2006 0.98
19 Effect of glutamine synthetase inhibition on astrocyte swelling and altered astroglial protein expression during hyperammonemia in rats. Neuroscience 2005 0.97
20 Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats. Stroke 1997 0.96
21 Fetal cerebral and peripheral circulatory responses to hypoxia after nitric oxide synthase inhibition. Am J Physiol Regul Integr Comp Physiol 2001 0.96
22 Effects of the AMPA receptor antagonist NBQX on outcome of newborn pigs after asphyxic cardiac arrest. J Cereb Blood Flow Metab 1999 0.96
23 Effect of hematocrit on cerebral blood flow. Am J Physiol 1986 0.95
24 Quantitative EEG during early recovery from hypoxic-ischemic injury in immature piglets: burst occurrence and duration. Clin Electroencephalogr 1999 0.94
25 Cerebral O2 transport with hematocrit reduced by cross-linked hemoglobin transfusion. Am J Physiol 1996 0.94
26 PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats. Stroke 1996 0.93
27 Methionine sulfoximine, a glutamine synthetase inhibitor, attenuates increased extracellular potassium activity during acute hyperammonemia. J Cereb Blood Flow Metab 1997 0.93
28 Deferoxamine reduces early metabolic failure associated with severe cerebral ischemic acidosis in dogs. Stroke 1995 0.93
29 Cerebral blood flow during hypoxic hypoxia with plasma-based hemoglobin at reduced hematocrit. Am J Physiol 1998 0.92
30 Contribution of epoxyeicosatrienoic acids to the hypoxia-induced activation of Ca2+ -activated K+ channel current in cultured rat hippocampal astrocytes. Neuroscience 2006 0.91
31 Effect of cross-linked hemoglobin transfusion on endothelial-dependent dilation in cat pial arterioles. Am J Physiol 1998 0.91
32 Developmental and regional differences in nitric oxide synthase activity and blood flow in the sheep brain. J Cereb Blood Flow Metab 1997 0.91
33 Epinephrine dosage effects on cerebral and myocardial blood flow in an infant swine model of cardiopulmonary resuscitation. Anesthesiology 1991 0.90
34 Nitric oxide synthase 1 and nitric oxide synthase 3 protein expression is regionally and temporally regulated in fetal brain. Brain Res Dev Brain Res 1996 0.90
35 Correlation of the average water diffusion constant with cerebral blood flow and ischemic damage after transient middle cerebral artery occlusion in cats. J Cereb Blood Flow Metab 1996 0.89
36 Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats. Stroke 1997 0.89
37 PPBP [4-phenyl-1-(4-phenylbutyl) piperidine], a potent sigma-receptor ligand, decreases brain injury after transient focal ischemia in cats. Stroke 1995 0.89
38 Restoration of cerebrovascular CO2 responsivity by glutamine synthesis inhibition in hyperammonemic rats. Circ Res 1992 0.89
39 Influence of arterial hypoxia on cardiac and coronary dynamics in the conscious sinoaortic-denervated dog. J Appl Physiol Respir Environ Exerc Physiol 1977 0.89
40 Impaired pial arteriolar reactivity to hypercapnia during hyperammonemia depends on glutamine synthesis. Stroke 1996 0.88
41 Cerebral and peripheral circulatory responses to intracranial hypertension in fetal sheep. Circ Res 1989 0.88
42 Pial arteriolar constriction to alpha 2-adrenergic agonist dexmedetomidine in the rat. Am J Physiol 1997 0.88
43 Oxygen delivery to the brain before and after birth. Science 1982 0.87
44 Interaction of CO2 and ammonia on cerebral blood flow and O2 consumption in dogs. Am J Physiol 1985 0.87
45 Cerebrovascular hypoxic and autoregulatory responses during reduced brain metabolism. Am J Physiol 1985 0.86
46 Cardiopulmonary bypass and the blood-brain barrier. An experimental study. J Thorac Cardiovasc Surg 1992 0.86
47 Augmentation of cerebral perfusion by simultaneous chest compression and lung inflation with abdominal binding after cardiac arrest in dogs. Circulation 1983 0.86
48 Hypertonic saline worsens infarct volume after transient focal ischemia in rats. Stroke 2000 0.85
49 An analysis of hypoxia in sheep brain using a mathematical model. Ann Biomed Eng 1999 0.85
50 Prostacyclin receptor deletion aggravates hippocampal neuronal loss after bilateral common carotid artery occlusion in mouse. Neuroscience 2008 0.84
51 Blood-brain barrier disruption after cardiopulmonary resuscitation in immature swine. Stroke 1991 0.84
52 Preserved hypocapnic pial arteriolar constriction during hyperammonemia by glutamine synthetase inhibition. Am J Physiol 1999 0.84
53 Reduced blood-brain barrier permeability after cardiac arrest by conjugated superoxide dismutase and catalase in piglets. Stroke 1994 0.83
54 Comparison of cerebrovascular response to hypoxic and carbon monoxide hypoxia in newborn and adult sheep. J Cereb Blood Flow Metab 1984 0.83
55 Effect of hematocrit on cerebral blood flow with induced polycythemia. J Appl Physiol (1985) 1987 0.83
56 Influence of reduced oxyhemoglobin affinity on cerebrovascular response to hypoxic hypoxia. Am J Physiol 1986 0.83
57 Monoclonal leukocyte antibody does not decrease the injury of transient focal cerebral ischemia in cats. Stroke 1992 0.83
58 Cerebral circulatory response to carbon monoxide and hypoxic hypoxia in the lamb. Am J Physiol 1982 0.83
59 Effects of fentanyl on peripheral and cerebral hemodynamics in neonatal lambs. Anesthesiology 1987 0.82
60 Preservation of cerebral blood flow responses to hypoxia and arterial pressure alterations in hyperammonemic rats. J Cereb Blood Flow Metab 1995 0.82
61 Improved blood flow during prolonged cardiopulmonary resuscitation with 30% duty cycle in infant pigs. Circulation 1991 0.82
62 Cardiovascular responses to arterial hypoxia in awake sinoaortic-denervated dogs. J Appl Physiol 1973 0.82
63 Intracellular pH during reperfusion influences evoked potential recovery after complete cerebral ischemia. Stroke 1993 0.82
64 GLT1, glial glutamate transporter, is transiently expressed in neurons and develops astrocyte specificity only after midgestation in the ovine fetal brain. J Neurobiol 1999 0.82
65 Dominant frequency analysis of EEG reveals brain's response during injury and recovery. IEEE Trans Biomed Eng 1996 0.82
66 Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo. J Cereb Blood Flow Metab 1997 0.82
67 Expiratory duration and abdominal muscle responses to elastic and resistive loading. J Appl Physiol Respir Environ Exerc Physiol 1979 0.81
68 Consistency of cerebral blood flow and evoked potential alterations with reversible focal ischemia in cats. Stroke 1990 0.81
69 Cell-free hemoglobin, oxygen off-load and vasoconstriction. Anasthesiol Intensivmed Notfallmed Schmerzther 2001 0.81
70 Blood flow during cardiopulmonary resuscitation with simultaneous compression and ventilation in infant pigs. Pediatr Res 1989 0.81
71 Regional and cellular expression of glial (GLT1) and neuronal (EAAC1) glutamate transporter proteins in ovine fetal brain. Neuroscience 1998 0.80
72 Circulatory dynamics during periodic intracranial hypertension in fetal sheep. Am J Physiol 1992 0.80
73 Sinoaortic contribution to the adjustment of systemic resistance in exercising dogs. J Appl Physiol 1974 0.80
74 Bicarbonate ion modulation of cerebral blood flow during hypoxia and hypercapnia. Am J Physiol 1982 0.80
75 Cerebral blood flow responsivity to CO2 in anesthetized chronically diabetic dogs. Am J Physiol 1993 0.80
76 Effect of epinephrine on cerebral and myocardial perfusion in an infant animal preparation of cardiopulmonary resuscitation. Circulation 1986 0.80
77 Comparative analysis of brain protection by N-methyl-D-aspartate receptor antagonists after transient focal ischemia in cats. Crit Care Med 1997 0.80
78 Conjugated superoxide dismutase reduces extent of caudate injury after transient focal ischemia in cats. Stroke 1991 0.80
79 Effect of lung volume on collateral ventilation in the dog. J Appl Physiol Respir Environ Exerc Physiol 1980 0.79
80 In vivo production of nitric oxide correlates with NMDA-induced cerebral hyperemia in newborn sheep. Am J Physiol 1995 0.79
81 Effect of adrenergic drugs on cerebral blood flow, metabolism, and evoked potentials after delayed cardiopulmonary resuscitation in dogs. Stroke 1991 0.79
82 Postischemic recovery rate of cerebral ATP, phosphocreatine, pH, and evoked potentials. Am J Physiol 1989 0.79
83 Hypercapnia and response of cerebral blood flow to hypoxia in newborn lambs. J Appl Physiol (1985) 1989 0.79
84 Sodium, ATP, and intracellular pH transients during reversible complete ischemia of dog cerebrum. Stroke 1991 0.79
85 Blood-brain barrier integrity during cardiopulmonary resuscitation in dogs. Stroke 1990 0.79
86 Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo. Stroke 1995 0.79
87 Efficacy of the cushing response in maintaining cerebral blood flow in premature and near-term fetal sheep. Pediatr Res 1998 0.79
88 Interaction of glutamine and arginine on cerebrovascular reactivity to hypercapnia. Am J Physiol Heart Circ Physiol 2000 0.79
89 Nitric oxide synthase inhibition reduces caudate injury following transient focal ischemia in cats. Stroke 1994 0.79
90 Interaction of fentanyl and nitrous oxide on peripheral and cerebral hemodynamics in newborn lambs. Anesthesiology 1994 0.78
91 Poor outcome after hypoxia-ischemia in newborns is associated with physiological abnormalities during early recovery. Possible relevance to secondary brain injury after head trauma in infants. Exp Toxicol Pathol 1999 0.78
92 Age-related effects of compression rate and duration in cardiopulmonary resuscitation. J Appl Physiol (1985) 1990 0.78
93 Shift reagent enhanced concurrent 23Na and 1H magnetic resonance spectroscopic studies of transcellular sodium distribution in the dog brain in vivo. Magn Reson Med 1993 0.78
94 Adrenal medullary and cortical blood flow during hemorrhage. Am J Physiol 1986 0.78
95 Effect of abdominal distension on central and regional hemodynamics in neonatal lambs. Pediatr Res 1985 0.78
96 Age-related cerebrovascular reactivity to CO2 after cerebral ischemia in swine. Am J Physiol 1991 0.78
97 Polyethylene glycol-conjugated superoxide dismutase improves recovery of postischemic hypercapnic cerebral blood flow in piglets. Pediatr Res 1993 0.78
98 Tirilazad mesylate does not improve early cerebral metabolic recovery following compression ischemia in dogs. Stroke 1992 0.78
99 Hypoxia, alpha 2-adrenergic, and nitric oxide-dependent interactions on canine cerebral blood flow. Am J Physiol 1994 0.78
100 Cerebral blood flow and metabolism in dogs with chronic diabetes. Anesthesiology 1993 0.78
101 Hemodilution causes size-dependent constriction of pial arterioles in the cat. Am J Physiol 1989 0.78
102 Beneficial effect of epinephrine infusion on cerebral and myocardial blood flows during CPR. Ann Emerg Med 1985 0.78
103 Competitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats. Stroke 1994 0.77
104 Tirilazad pretreatment improves early cerebral metabolic and blood flow recovery from hyperglycemic ischemia. J Cereb Blood Flow Metab 1995 0.77
105 Distribution of cardiac output in fetal and neonatal lambs with acute respiratory acidosis. Pediatr Res 1984 0.77
106 Glutamine synthetase inhibition prevents cerebral oedema during hyperammonemia. Acta Neurochir Suppl (Wien) 1990 0.77
107 Arterial pH modulation of regional cerebral blood flow during hyperammonemia in dogs. Am J Physiol 1990 0.77
108 Dependence of cerebral energy phosphate and evoked potential recovery on end-ischemic pH. Am J Physiol 1991 0.77
109 Base-line O2 extraction influences cerebral blood flow response to hematocrit. Am J Physiol 1988 0.77
110 Poor hemodynamic and metabolic recovery after global incomplete cerebral ischemia associated with short-term diabetes in dogs. J Cereb Blood Flow Metab 1995 0.77
111 Effect of the no-flow interval and hypothermia on cerebral blood flow and metabolism during cardiopulmonary resuscitation in dogs. Stroke 1998 0.77
112 Effect of jugular venous pressure on cerebral autoregulation in dogs. Am J Physiol 1988 0.77
113 Somatosensory evoked potential and brain water content in post-asphyxic immature piglets. Pediatr Res 1995 0.77
114 Role of nitric oxide scavenging in peripheral vasoconstrictor response to beta beta cross-linked hemoglobin. Artif Cells Blood Substit Immobil Biotechnol 1995 0.77
115 Alkalemia reduces recovery from global cerebral ischemia by NMDA receptor-mediated mechanism. Am J Physiol 1997 0.76
116 Role of O2-hemoglobin affinity in the regulation of cerebral blood flow in fetal sheep. Am J Physiol 1986 0.76
117 Blood-brain barrier permeability during dopamine-induced hypertension in fetal sheep. J Appl Physiol (1985) 2001 0.76
118 Diabetic chronic hyperglycemia and cerebral pH recovery following global ischemia in dogs. Stroke 1994 0.76
119 Intraventricular dexmedetomidine decreases cerebral blood flow during normoxia and hypoxia in dogs. Anesth Analg 1997 0.76
120 Amelioration of impaired cerebral metabolism after severe acidotic ischemia by tirilazad posttreatment in dogs. Stroke 1996 0.76
121 Hypoglycemia and cerebral autoregulation in anesthetized dogs. Am J Physiol 1990 0.75
122 Blood viscosity modulates tissue perfusion: sometimes and somewhere. Transfus Altern Transfus Med 2008 0.75
123 Age-related changes in chest geometry during cardiopulmonary resuscitation. J Appl Physiol (1985) 1987 0.75
124 Rapid measurement of somatosensory evoked potential response to cerebral artery occlusion. Med Biol Eng Comput 1995 0.75
125 Effect of cerebral blood flow generated during cardiopulmonary resuscitation in dogs on maintenance versus recovery of ATP and pH. Stroke 1993 0.75
126 Brain bioenergetics during cardiopulmonary resuscitation in dogs. Anesthesiology 1992 0.75
127 Acidemia and brain pH during prolonged cardiopulmonary resuscitation in dogs. Stroke 1995 0.75
128 Effect of hypovolemic hypotension and laparotomy on splanchnic and hepatic arterial blood flow in dogs. Curr Surg 1982 0.75
129 Effect of the 21-aminosteroid tirilazad on cerebral pH and somatosensory evoked potentials after incomplete ischemia. Stroke 1993 0.75
130 Chemodenervation does not alter cerebrovascular response to hypoxic hypoxia. Am J Physiol 1989 0.75
131 Cerebrovascular and metabolic responses to hypoxia during hypoglycemia in dogs. Am J Physiol 1990 0.75
132 Efficacy of Cushing response during development in sheep. Am J Physiol 1991 0.75
133 Effect of vest cardiopulmonary resuscitation on cerebral and coronary perfusion in an infant porcine model. Crit Care Med 1994 0.75
134 Effect of hypoxemia on the cardiovascular response to intracranial hypertension in postnatal lambs. Am J Physiol 1993 0.75
135 Relationship of diaphragmatic contractility to diaphragmatic blood flow in newborn lambs. J Appl Physiol (1985) 1989 0.75
136 Sustained endothelial dependent dilation in pial arterioles after crosslinked hemoglobin transfusion. Artif Cells Blood Substit Immobil Biotechnol 1997 0.75
137 Cerebral blood flow autoregulation during intracranial hypertension in hypoxic lambs. Am J Physiol 1987 0.75
138 Tirilazad treatment does not decrease early brain injury after transient focal ischemia in cats. Stroke 1994 0.75
139 Organ blood flow and somatosensory-evoked potentials during and after cardiopulmonary resuscitation with epinephrine or phenylephrine. Circulation 1989 0.75
140 Effect of mefenidil on cerebral and peripheral hemodynamics in dogs. J Pharmacol Exp Ther 1985 0.75
141 Role of O2-hemoglobin affinity on cerebrovascular response to carbon monoxide hypoxia. Am J Physiol 1983 0.75
142 Bicarbonate conservation during incomplete cerebral ischemia with superimposed hypercapnia. Am J Physiol 1991 0.75
143 Diaphragmatic fatigue assessed by 31P-magnetic resonance spectroscopy in vivo. Am J Physiol 1993 0.75
144 Simulation of the oxygen distribution in brain tissue perfused with fluorocarbons. Adv Exp Med Biol 1997 0.75
145 Precautions for measuring blood flow during anemia with the microsphere technique. Am J Physiol 1983 0.75
146 Nitric oxide production in the CA1 field of the gerbil hippocampus after transient forebrain ischemia : effects of 7-nitroindazole and NG-nitro-L-arginine methyl ester. Stroke 1999 0.75
147 Regional blood flow and O2 transport during hypoxic and CO hypoxia in neonatal and adult sheep. Am J Physiol 1985 0.75
148 Hypocapnic-hypoglycemic interactions on cerebral high-energy phosphates and pH in dogs. Am J Physiol 1992 0.75
149 Heart rate and rhythm and intracranial pressure. Am J Physiol 1976 0.75
150 Intravenous basic fibroblast growth factor does not ameliorate brain injury resulting from transient focal ischemia in cats. J Neurosurg Anesthesiol 1998 0.75
151 Blood-brain barrier disruption following CPR in piglets. Acta Neurochir Suppl (Wien) 1990 0.75