Published in J Biochem on December 01, 2004
The control of mRNA decapping and P-body formation. Mol Cell (2008) 3.58
Decapping is preceded by 3' uridylation in a novel pathway of bulk mRNA turnover. Nat Struct Mol Biol (2009) 2.30
Arabidopsis DCP2, DCP1, and VARICOSE form a decapping complex required for postembryonic development. Plant Cell (2006) 2.13
Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe. Nat Struct Mol Biol (2005) 1.88
Structural basis of dcp2 recognition and activation by dcp1. Mol Cell (2008) 1.65
DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Proc Natl Acad Sci U S A (2009) 1.08
Dcp2 Decaps m2,2,7GpppN-capped RNAs, and its activity is sequence and context dependent. Mol Cell Biol (2005) 1.08
Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan. Proc Natl Acad Sci U S A (2012) 0.94
The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1. Nucleic Acids Res (2014) 0.92
Dehydration stress activates Arabidopsis MPK6 to signal DCP1 phosphorylation. EMBO J (2012) 0.92
Pdc1 functions in the assembly of P bodies in Schizosaccharomyces pombe. Mol Cell Biol (2013) 0.89
Mating pheromone in Cryptococcus neoformans is regulated by a transcriptional/degradative "futile" cycle. J Biol Chem (2010) 0.85
Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systems. RNA Biol (2014) 0.83
Phosphorylation of mRNA decapping protein Dcp1a by the ERK signaling pathway during early differentiation of 3T3-L1 preadipocytes. PLoS One (2013) 0.78
The Evolution of Function within the Nudix homology Clan. Proteins (2016) 0.75
GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease. Biochemistry (2007) 2.71
A novel role of the mammalian GSPT/eRF3 associating with poly(A)-binding protein in Cap/Poly(A)-dependent translation. J Biol Chem (2002) 2.43
Novel role of the small GTPase Rheb: its implication in endocytic pathway independent of the activation of mammalian target of rapamycin. J Biochem (2005) 2.28
Translation termination factor eRF3 mediates mRNA decay through the regulation of deadenylation. J Biol Chem (2003) 1.85
An in vivo model for monitoring trans-differentiation of bone marrow cells into functional hepatocytes. J Biochem (2003) 1.81
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia. Nat Methods (2013) 1.76
An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregation. Neuron (2010) 1.70
Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases. Genes Dev (2007) 1.68
A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech Dev (2004) 1.65
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans. J Cell Biol (2010) 1.60
Compressed true lumen in the innominate artery: a pitfall of right axillary arterial perfusion in acute aortic dissection. J Thorac Cardiovasc Surg (2008) 1.58
Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein. J Biol Chem (2003) 1.58
Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway. J Biochem (2008) 1.52
MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence. Nat Cell Biol (2004) 1.51
Mammalian phosphoinositide kinases and phosphatases. Prog Lipid Res (2009) 1.48
The CENP-A chaperone Scm3 becomes enriched at kinetochores in anaphase independently of CENP-A incorporation. Cell Cycle (2011) 1.47
Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast. EMBO J (2003) 1.47
RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway. J Cell Sci (2003) 1.47
cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites. Mol Biol Cell (2011) 1.39
Mid-term results of the box pulmonary vein isolation and the cryo-maze procedure for chronic atrial fibrillation associated with mitral valve disease. Gen Thorac Cardiovasc Surg (2012) 1.39
Efficacy of cardiopulmonary rehabilitation with adaptive servo-ventilation in patients undergoing off-pump coronary artery bypass grafting. Circ J (2015) 1.39
LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1. Proc Natl Acad Sci U S A (2007) 1.23
Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function. J Biol Chem (2001) 1.21
The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death. Nature (2010) 1.21
A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5. J Biol Chem (2001) 1.21
The GTP-binding release factor eRF3 as a key mediator coupling translation termination to mRNA decay. J Biol Chem (2004) 1.20
Systematic approaches to using the FOX hunting system to identify useful rice genes. Plant J (2008) 1.20
Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol Cell Biol (2007) 1.19
Phenome analysis in plant species using loss-of-function and gain-of-function mutants. Plant Cell Physiol (2009) 1.16
Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells. J Biol Chem (2003) 1.11
Physiological roles of SAPK/JNK signaling pathway. J Biochem (2004) 1.10
Endovascular aortic repair as second-stage surgery after hybrid open arch repair by the frozen elephant trunk technique for extended thoracic aneurysm. Ann Thorac Cardiovasc Surg (2012) 1.09
Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation. J Cell Sci (2004) 1.09
Transforming mutations of RAC guanosine triphosphatases in human cancers. Proc Natl Acad Sci U S A (2013) 1.07
Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast. RNA (2008) 1.06
The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein. J Biol Chem (2003) 1.06
The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans. Mol Biol Cell (2010) 1.05
Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis. EMBO J (2007) 1.05
Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activation. EMBO J (2006) 1.02
C. elegans AMPKs promote survival and arrest germline development during nutrient stress. Biol Open (2012) 1.02
Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome. Biochem Biophys Res Commun (2009) 1.02
A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents. J Biol Chem (2012) 1.02
Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase. EMBO J (2011) 1.00
Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain. PLoS Genet (2013) 1.00
RiceFOX: a database of Arabidopsis mutant lines overexpressing rice full-length cDNA that contains a wide range of trait information to facilitate analysis of gene function. Plant Cell Physiol (2010) 0.99
Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. J Neurosci (2011) 0.97
Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand. J Bone Miner Res (2002) 0.96
SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis. Dev Biol (2002) 0.96
The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells. J Biol Chem (2013) 0.95
Di-Ras, a distinct subgroup of ras family GTPases with unique biochemical properties. J Biol Chem (2002) 0.95
Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation. Biochem Biophys Res Commun (2008) 0.94
Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress. J Vasc Surg (2010) 0.93
Novel antibody to human BASP1 labels apoptotic cells post-caspase activation. Biochem Biophys Res Commun (2008) 0.93
New method for absolute spinal cord ischemia protection in rabbits. J Vasc Surg (2011) 0.93
Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine. Proc Natl Acad Sci U S A (2013) 0.91
The LIM protein Ajuba is required for ciliogenesis and left-right axis determination in medaka. Biochem Biophys Res Commun (2010) 0.91
Caf1 regulates translocation of ribonucleotide reductase by releasing nucleoplasmic Spd1-Suc22 assembly. Nucleic Acids Res (2007) 0.91
Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation. J Biol Chem (2010) 0.91
Activation mechanism of Gi and Go by reactive oxygen species. J Biol Chem (2002) 0.91
Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase. Biochem Biophys Res Commun (2007) 0.90
Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation. J Cell Biochem (2010) 0.89
Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans. Mol Biol Cell (2013) 0.88
p38 Mitogen-activated protein kinase controls a switch between cardiomyocyte and neuronal commitment of murine embryonic stem cells by activating myocyte enhancer factor 2C-dependent bone morphogenetic protein 2 transcription. Stem Cells Dev (2010) 0.88
Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31. J Biol Chem (2011) 0.87
Extended aortic repair using frozen elephant trunk technique for Marfan syndrome with acute aortic dissection. Ann Thorac Cardiovasc Surg (2012) 0.86
RhoA activation participates in rearrangement of processing bodies and release of nucleated AU-rich mRNAs. Nucleic Acids Res (2011) 0.85
Human CD38 interferes with HIV-1 fusion through a sequence homologous to the V3 loop of the viral envelope glycoprotein gp120. FASEB J (2003) 0.85
Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities. Structure (2012) 0.85
The microRNA miR-235 couples blast-cell quiescence to the nutritional state. Nature (2013) 0.85
Stress induces mitochondria-mediated apoptosis independent of SAPK/JNK activation in embryonic stem cells. J Biol Chem (2003) 0.85
Treatment strategy for acute type a aortic dissection complicated with organ ischemia. Ann Vasc Dis (2011) 0.84
Alteration of enzymatic properties of cell-surface antigen CD38 by agonistic anti-CD38 antibodies that prolong B cell survival and induce activation. Int Immunopharmacol (2007) 0.84
Purification and analysis of RIN family-novel Rab5 GEFs. Methods Enzymol (2005) 0.84
Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release. J Biol Chem (2002) 0.84
Induction and inhibition of cyclobutane pyrimidine dimer photolyase in etiolated cucumber (Cucumis sativus) cotyledons after ultraviolet irradiation depends on wavelength. J Plant Res (2007) 0.83
A subpopulation of bone marrow cells depleted by a novel antibody, anti-Liv8, is useful for cell therapy to repair damaged liver. Biochem Biophys Res Commun (2004) 0.83
Tyr-phosphorylation signals translocate RIN3, the small GTPase Rab5-GEF, to early endocytic vesicles. Biochem Biophys Res Commun (2008) 0.82
Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria. Mech Dev (2004) 0.82
RINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odin. PLoS One (2012) 0.82
Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans. Genes Cells (2012) 0.81
Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay. RNA (2012) 0.81
Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in medaka. Hepatology (2010) 0.80
Requirement of MKK4 and MKK7 for CdCl2- or HgCl2-induced activation of c-Jun NH2-terminal kinase in mouse embryonic stem cells. Toxicol Lett (2004) 0.80
Low-dose edaravone injection into the clamped aorta prevents ischemic spinal cord injury. Ann Vasc Surg (2008) 0.80
Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation. Biochem J (2010) 0.80