PubRank

Lenny Dang

Author PubWeight™ 44.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 2007 7.10
2 Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med 2010 5.68
3 NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem 2002 4.94
4 Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clin Cancer Res 2005 4.84
5 Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science 2013 3.72
6 Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol 2012 3.40
7 Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma. Blood 2007 3.00
8 MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma. Blood 2010 2.49
9 Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2010 2.21
10 Small molecule activation of PKM2 in cancer cells induces serine auxotrophy. Chem Biol 2012 1.96
11 MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo. Clin Cancer Res 2006 1.75
12 Interleukin 6, a nuclear factor-kappaB target, predicts resistance to docetaxel in hormone-independent prostate cancer and nuclear factor-kappaB inhibition by PS-1145 enhances docetaxel antitumor activity. Clin Cancer Res 2006 1.61
13 Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. Proc Natl Acad Sci U S A 2008 1.42
14 A high-throughput liposome substrate assay with automated lipid extraction process for PI 3-kinase. J Biomol Screen 2008 0.78
15 A biocatalyst inspired by cancer. Nat Chem Biol 2012 0.75