PubRank

Pier Giorgio Natali

Author PubWeight™ 78.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells. Cancer Res 2005 1.69
2 Molecular cloning of hMena (ENAH) and its splice variant hMena+11a: epidermal growth factor increases their expression and stimulates hMena+11a phosphorylation in breast cancer cell lines. Cancer Res 2007 1.65
3 Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci U S A 2009 1.59
4 Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells. J Biol Chem 2002 1.56
5 Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells. Clin Cancer Res 2011 1.53
6 Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels. Oncogene 2003 1.49
7 Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response. Int J Cancer 2004 1.45
8 The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells. Oncogene 2002 1.44
9 Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines. Clin Cancer Res 2008 1.44
10 The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors. Clin Cancer Res 2006 1.41
11 Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues. J Cell Physiol 2008 1.25
12 Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression. Cancer Res 2004 1.22
13 Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade. Cancer Res 2009 1.19
14 Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients. Int J Cancer 2009 1.18
15 Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells. Breast Cancer Res 2010 1.16
16 Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma. Mol Cancer Ther 2006 1.08
17 Endothelin receptors as novel targets in tumor therapy. J Transl Med 2004 1.07
18 A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study. Breast Cancer Res 2008 1.06
19 Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells. Neoplasia 2011 1.06
20 Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells. J Biol Chem 2003 1.05
21 Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma. Cancer Res 2003 1.03
22 Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells. Cancer Res 2007 1.03
23 Ferritin contributes to melanoma progression by modulating cell growth and sensitivity to oxidative stress. Clin Cancer Res 2005 1.02
24 Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion. J Biol Chem 2004 1.00
25 Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells. Clin Cancer Res 2004 0.99
26 Growth inhibition of cervix carcinoma cells in vivo by endothelin A receptor blockade. Cancer Res 2002 0.98
27 Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells. PLoS One 2010 0.98
28 Combined targeting of endothelin A receptor and epidermal growth factor receptor in ovarian cancer shows enhanced antitumor activity. Cancer Res 2007 0.98
29 Cancer testis antigens in human melanoma stem cells: expression, distribution, and methylation status. J Cell Physiol 2008 0.97
30 ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo. Mol Cancer Ther 2007 0.96
31 Identification of genes down-regulated during melanoma progression: a cDNA array study. Exp Dermatol 2003 0.95
32 Flavonoids inhibit melanoma lung metastasis by impairing tumor cells endothelium interactions. J Cell Physiol 2006 0.95
33 c-Kit is preferentially expressed in MYCN-amplified neuroblastoma and its effect on cell proliferation is inhibited in vitro by STI-571. Int J Cancer 2003 0.94
34 Dacarbazine treatment before peptide vaccination enlarges T-cell repertoire diversity of melan-a-specific, tumor-reactive CTL in melanoma patients. Cancer Res 2010 0.93
35 Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells. J Mol Med (Berl) 2012 0.93
36 NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells. Cancer Res 2010 0.93
37 Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications. J Cell Physiol 2006 0.90
38 cDNA-array profiling of melanomas and paired melanocyte cultures. J Cell Physiol 2006 0.90
39 Evaluation of MicroRNA expression pattern of gastric adenocarcinoma associated with socioeconomic, environmental and lifestyle factors in northwestern Hungary. Anticancer Res 2013 0.90
40 Overexpression of activated phospholipase Cγ1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapy. Int J Cancer 2012 0.89
41 The synergistic activity of thyroid transcription factor 1 and Pax 8 relies on the promoter/enhancer interplay. Mol Endocrinol 2002 0.89
42 The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor. Carcinogenesis 2014 0.88
43 Analysis of APAF-1 expression in human cutaneous melanoma progression. Exp Dermatol 2004 0.88
44 Endothelin-1 is required during epithelial to mesenchymal transition in ovarian cancer progression. Exp Biol Med (Maywood) 2006 0.88
45 Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma. Mol Cancer Ther 2006 0.88
46 Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo. Am J Pathol 2003 0.88
47 Retinoblastoma protein acts as Pax 8 transcriptional coactivator. Oncogene 2005 0.87
48 Understanding human cancer using Drosophila: Tid47, a cytosolic product of the DnaJ-like tumor suppressor gene l2Tid, is a novel molecular partner of patched related to skin cancer. J Biol Chem 2003 0.87
49 LMNA knock-down affects differentiation and progression of human neuroblastoma cells. PLoS One 2012 0.86
50 Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients. J Transl Med 2009 0.86
51 Endothelin-1 promotes proteolytic activity of ovarian carcinoma. Clin Sci (Lond) 2002 0.85
52 Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors. PLoS One 2012 0.85
53 Laminin alpha2 chain-positive vessels and epidermal growth factor in lung neuroendocrine carcinoma: a model of a novel cooperative role of laminin-2 and epidermal growth factor in vessel neoplastic invasion and metastasis. Am J Pathol 2006 0.83
54 Melanoma molecular classes and prognosis in the postgenomic era. Lancet Oncol 2012 0.83
55 Prognostic value of HER2 and progesterone receptor expression in endometrial carcinoma with positive peritoneal washing. Anticancer Res 2007 0.83
56 Combination therapy of zibotentan with cisplatinum and paclitaxel is an effective regimen for epithelial ovarian cancer. Can J Physiol Pharmacol 2010 0.82
57 Endothelin axis induces metalloproteinase activation and invasiveness in human lymphatic endothelial cells. Can J Physiol Pharmacol 2010 0.81
58 Altered expression of FAS system is related to adverse clinical outcome in stage I-II breast cancer patients treated with adjuvant anthracycline-based chemotherapy. Clin Cancer Res 2004 0.81
59 5-AZA-2'-deoxycytidine in cancer immunotherapy: a mouse to man story. Cancer Res 2007 0.81
60 ZD4054, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma cell proliferation. Exp Biol Med (Maywood) 2006 0.81
61 Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems. J Transl Med 2006 0.81
62 Endothelin-B receptor blockade inhibits molecular effectors of melanoma cell progression. J Cardiovasc Pharmacol 2004 0.81
63 A melanoma immune response signature including Human Leukocyte Antigen-E. Pigment Cell Melanoma Res 2013 0.81
64 Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain. Int J Cancer 2003 0.80
65 Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea. J Cell Physiol 2006 0.80
66 CD40 expression by human melanocytic lesions and melanoma cell lines and direct CD40 targeting with the therapeutic anti-CD40 antibody CP-870,893. J Immunother 2010 0.80
67 Progression of colorectal cancers correlates with overexpression and loss of polarization of expression of the htid-1 tumor suppressor. Int J Mol Med 2008 0.80
68 Skin cancer risk factors among primary school children: investigations in Western Hungary. Prev Med 2010 0.80
69 The "Excellence in Translational Medicine" and "Bedside-to-Bench" Awards 2008-09. J Transl Med 2010 0.80
70 Targeting endothelin axis in cancer. Cancer Treat Res 2004 0.80
71 Antitumor effect of green tea polyphenol epigallocatechin-3-gallate in ovarian carcinoma cells: evidence for the endothelin-1 as a potential target. Exp Biol Med (Maywood) 2006 0.79
72 Expression and regulation of B7-H3 immunoregulatory receptor, in human mesothelial and mesothelioma cells: immunotherapeutic implications. J Cell Physiol 2011 0.79
73 Identification of the minimal melanocyte-specific promoter in the melanocortin receptor 1 gene. J Exp Clin Cancer Res 2008 0.78
74 Differential expression of UN1, early thymocyte-associated sialoglycoprotein, in breast normal tissue, benign disease and carcinomas. Anticancer Res 2002 0.78
75 Phenotypic changes of p53, HER2, and FAS system in multiple normal tissues surrounding breast cancer. J Cell Physiol 2005 0.78
76 Beta-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase. Can J Physiol Pharmacol 2010 0.77
77 Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor. J Cardiovasc Pharmacol 2004 0.77
78 Therapeutic targeting of the endothelin-A receptor in human ovarian carcinoma: efficacy of cytotoxic agents is markedly enhanced by co-administration with atrasentan. J Cardiovasc Pharmacol 2004 0.76
79 Clinical and molecular evidence for c-kit receptor as a therapeutic target in neuroblastic tumors. Clin Cancer Res 2005 0.76
80 Prognostic factors in Hungarian breast cancer patients. Anticancer Res 2007 0.76
81 The "Excellence in Translational Medicine" and "Bedside-to-Bench" Awards 2007-08. J Transl Med 2009 0.75
82 [Skin cancer risk factors in childhood: findings of a survey in an Italian area characterized by atypical migration]. Epidemiol Prev 2009 0.75
83 [Skin cancer risk factors in childhood: findings of a survey conducted within Italian areas with a different incidence of melanoma]. Epidemiol Prev 2011 0.75
84 45th annual meeting of the Italian Cancer Society. Bergamo, 9-12 November 2003. Tumori 2004 0.75
85 ABT-627, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma growth in vitro. Clin Sci (Lond) 2002 0.75