|
1
|
Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines.
|
Clin Cancer Res
|
2006
|
3.65
|
|
2
|
Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells.
|
Oncogene
|
2005
|
2.24
|
|
3
|
Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells.
|
Cancer Res
|
2006
|
1.99
|
|
4
|
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor.
|
Clin Cancer Res
|
2005
|
1.83
|
|
5
|
Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation.
|
J Natl Cancer Inst
|
2004
|
1.82
|
|
6
|
The development and characterization of a human midgut carcinoid cell line.
|
Clin Cancer Res
|
2007
|
1.80
|
|
7
|
Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines.
|
Cancer
|
2005
|
1.64
|
|
8
|
Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors.
|
Cancer Res
|
2003
|
1.61
|
|
9
|
Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer.
|
Lab Invest
|
2002
|
1.57
|
|
10
|
Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content.
|
J Clin Invest
|
2007
|
1.47
|
|
11
|
Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer.
|
Am J Pathol
|
2003
|
1.45
|
|
12
|
Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
|
Cancer Res
|
2005
|
1.45
|
|
13
|
Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer.
|
Clin Cancer Res
|
2002
|
1.44
|
|
14
|
A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model.
|
Clin Cancer Res
|
2005
|
1.42
|
|
15
|
Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice.
|
Cancer Res
|
2003
|
1.41
|
|
16
|
Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells.
|
Mol Cancer Ther
|
2006
|
1.39
|
|
17
|
Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice.
|
Int J Cancer
|
2003
|
1.35
|
|
18
|
RON, a tyrosine kinase receptor involved in tumor progression and metastasis.
|
Ann Surg Oncol
|
2005
|
1.30
|
|
19
|
Biology of angiogenesis in tumors of the gastrointestinal tract.
|
Microsc Res Tech
|
2003
|
1.11
|
|
20
|
ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer.
|
Mol Cancer Ther
|
2004
|
1.09
|
|
21
|
Role of P38 MAPK, AP-1, and NF-kappaB in interleukin-1beta-induced IL-8 expression in human vascular smooth muscle cells.
|
Cytokine
|
2002
|
1.07
|
|
22
|
The role of the microenvironment and intercellular cross-talk in tumor angiogenesis.
|
Semin Cancer Biol
|
2002
|
1.06
|
|
23
|
Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor.
|
Ann Surg
|
2005
|
1.06
|
|
24
|
Roles of nitric oxide synthase inhibition and vascular endothelial growth factor receptor-2 inhibition on vascular morphology and function in an in vivo model of pancreatic cancer.
|
Clin Cancer Res
|
2006
|
1.01
|
|
25
|
Role of angiogenesis in the development and growth of liver metastasis.
|
Ann Surg Oncol
|
2002
|
1.01
|
|
26
|
Angiogenesis and antiangiogenic therapy of colon cancer liver metastasis.
|
Ann Surg Oncol
|
2003
|
0.99
|
|
27
|
Interleukin-1beta regulates angiopoietin-1 expression in human endothelial cells.
|
Cancer Res
|
2004
|
0.98
|
|
28
|
Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice.
|
Ann Surg Oncol
|
2007
|
0.97
|
|
29
|
Oncolysis by viral replication and inhibition of angiogenesis by a replication-conditional herpes simplex virus that expresses mouse endostatin.
|
Cancer
|
2004
|
0.87
|
|
30
|
Promises and pitfalls of anti-angiogenic therapy in clinical trials.
|
Trends Mol Med
|
2003
|
0.86
|
|
31
|
Regulation of cyclooxygenase-2 (COX-2) expression in human pancreatic carcinoma cells by the insulin-like growth factor-I receptor (IGF-IR) system.
|
Cancer Lett
|
2007
|
0.81
|
|
32
|
Improving delivery of antineoplastic agents with anti-vascular endothelial growth factor therapy.
|
Cancer
|
2005
|
0.80
|
|
33
|
Synopsis of angiogenesis inhibitors in oncology.
|
Oncology (Williston Park)
|
2002
|
0.78
|
|
34
|
Angiopoietins and their role in colon cancer angiogenesis.
|
Oncology (Williston Park)
|
2002
|
0.78
|
|
35
|
Regulation of vascular endothelial growth factor expression in human gastric cancer cells by interleukin-1beta.
|
Surgery
|
2004
|
0.77
|