Paula Soares

Author PubWeight™ 87.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Frequency of TERT promoter mutations in human cancers. Nat Commun 2013 3.13
2 The mTOR signalling pathway in human cancer. Int J Mol Sci 2012 2.38
3 BRAF mutations are associated with some histological types of papillary thyroid carcinoma. J Pathol 2004 2.21
4 TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas. J Clin Endocrinol Metab 2014 1.71
5 Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients' age but not with tumour aggressiveness. Virchows Arch 2005 1.62
6 Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors. Am J Pathol 2002 1.61
7 BRAF mutations are not a major event in post-Chernobyl childhood thyroid carcinomas. J Clin Endocrinol Metab 2004 1.52
8 How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer. J Thyroid Res 2011 1.46
9 Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines. Thyroid 2007 1.41
10 Mutation analysis of B-RAF gene in human gliomas. Acta Neuropathol 2004 1.39
11 Diffuse (or multinodular) follicular variant of papillary thyroid carcinoma: a clinicopathologic and immunohistochemical analysis of ten cases of an aggressive form of differentiated thyroid carcinoma. Virchows Arch 2001 1.30
12 STAT3 negatively regulates thyroid tumorigenesis. Proc Natl Acad Sci U S A 2012 1.23
13 Telomerase promoter mutations in cancer: an emerging molecular biomarker? Virchows Arch 2014 1.09
14 mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma. J Clin Endocrinol Metab 2012 1.08
15 Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma. Melanoma Res 2010 1.08
16 Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma. Lab Invest 2002 1.05
17 Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review. Sao Paulo Med J 2012 1.04
18 A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma. Hum Pathol 2005 1.04
19 Multicentre validation study of nucleic acids extraction from FFPE tissues. Virchows Arch 2010 1.01
20 Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. Mod Pathol 2004 1.01
21 Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas. Br J Ophthalmol 2010 1.01
22 Intragenic mutations in thyroid cancer. Endocrinol Metab Clin North Am 2008 1.00
23 Hürthle (oncocytic) cell tumors of thyroid: etiopathogenesis, diagnosis and clinical significance. Int J Surg Pathol 2005 1.00
24 p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin. Mod Pathol 2003 0.99
25 Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation. Mol Biol Cell 2008 0.95
26 Insights into melanoma: targeting the mTOR pathway for therapeutics. Expert Opin Ther Targets 2012 0.93
27 The biology and the genetics of Hurthle cell tumors of the thyroid. Endocr Relat Cancer 2012 0.92
28 Poorly differentiated carcinomas of the thyroid gland: a review of the clinicopathologic features of a series of 28 cases of a heterogeneous, clinically aggressive group of thyroid tumors. Int J Surg Pathol 2002 0.92
29 Molecular genetics of papillary thyroid carcinoma: great expectations. Arq Bras Endocrinol Metabol 2007 0.92
30 Cribriform-morular variant of papillary thyroid carcinoma: molecular characterization of a case with neuroendocrine differentiation and aggressive behavior. Am J Clin Pathol 2009 0.91
31 B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas. Hum Pathol 2006 0.91
32 A follicular variant of papillary thyroid carcinoma in struma ovarii. Case report with unique molecular alterations. Histopathology 2009 0.91
33 Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia. J Clin Endocrinol Metab 2003 0.90
34 Molecular pathology of well-differentiated thyroid carcinomas. Virchows Arch 2005 0.90
35 Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone. Biochim Biophys Acta 2011 0.89
36 Mutated E-cadherin: genomic and functional characterization in thyroid cells from the KAT family. Thyroid 2004 0.88
37 Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes. Genes Chromosomes Cancer 2012 0.88
38 A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney-Stratakis dyad. Fam Cancer 2012 0.87
39 A polymorphism in the promoter region of the selenoprotein S gene (SEPS1) contributes to Hashimoto's thyroiditis susceptibility. J Clin Endocrinol Metab 2014 0.86
40 Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas. Melanoma Res 2016 0.86
41 Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations. BMC Cancer 2009 0.86
42 Thyroid hormone as a regulator of tumor induced angiogenesis. Cancer Lett 2010 0.86
43 Impact of EGFR genetic variants on glioma risk and patient outcome. Cancer Epidemiol Biomarkers Prev 2011 0.86
44 Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes. J Pathol 2005 0.85
45 Occurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal. Clin Endocrinol (Oxf) 2006 0.85
46 Cancer: Small papillary thyroid cancers--is BRAF of prognostic value? Nat Rev Endocrinol 2011 0.85
47 Thyroid hormone receptor beta mutations in the 'hot-spot region' are rare events in thyroid carcinomas. J Endocrinol 2007 0.85
48 Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production. Microsc Res Tech 2003 0.85
49 RET/PTC rearrangement is prevalent in follicular Hürthle cell carcinomas. Histopathology 2012 0.85
50 Stimulated thyroglobulin at recombinant human TSH-aided ablation predicts disease-free status one year later. J Clin Endocrinol Metab 2013 0.84
51 A stem cell role for thyroid solid cell nests. Hum Pathol 2005 0.84
52 The p75 neurotrophin receptor is widely expressed in conventional papillary thyroid carcinoma. Hum Pathol 2006 0.83
53 P63 expression in papillary and anaplastic carcinomas of the thyroid gland: lack of an oncogenetic role in tumorigenesis and progression. Pathol Res Pract 2002 0.83
54 Loss of heterozygosity at 19p13.2 and 2q21 in tumours from familial clusters of non-medullary thyroid carcinoma. Fam Cancer 2007 0.83
55 Impact of pelvic radiotherapy on female sexuality. Arch Gynecol Obstet 2011 0.82
56 GRIM-19 in Health and Disease. Adv Anat Pathol 2008 0.82
57 Head and neck basal cell carcinoma prevalence in individuals submitted to childhood X-ray epilation for tinea capitis treatment. Eur J Dermatol 2012 0.82
58 An assessment of the clonality of the components of canine mixed mammary tumours by mitochondrial DNA analysis. Vet J 2008 0.81
59 Absence of the BRAF and the GRIM-19 mutations in oncocytic (Hürthle cell) solid cell nests of the thyroid. Am J Clin Pathol 2012 0.81
60 Acquisition of BRAF gene mutations is not a requirement for nodal metastasis of papillary thyroid carcinoma. Clin Endocrinol (Oxf) 2008 0.81
61 Mitochondria and cancer. Virchows Arch 2009 0.81
62 The preeminence of growth pattern and invasiveness and the limited influence of BRAF and RAS mutations in the occurrence of papillary thyroid carcinoma lymph node metastases. Virchows Arch 2011 0.81
63 GRIM-19 function in cancer development. Mitochondrion 2011 0.80
64 Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells. J Clin Endocrinol Metab 2013 0.80
65 Head and neck lesions in a cohort irradiated in childhood for tinea capitis treatment. Lancet Infect Dis 2011 0.80
66 Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors. Eur J Hum Genet 2012 0.80
67 AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines. PLoS One 2012 0.80
68 Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death. J Biosci 2011 0.80
69 A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation. Virchows Arch 2007 0.80
70 CDX2 Expression in Some Variants of Papillary Thyroid Carcinoma. Am J Clin Pathol 2012 0.79
71 Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component? Int J Surg Pathol 2011 0.79
72 Volkmann ischemic contracture in a newborn. BMJ Case Rep 2011 0.79
73 Mitochondrial D-Loop instability in thyroid tumours is not a marker of malignancy. Mitochondrion 2005 0.78
74 A clear cell renal cell carcinoma inhibiting the response to intravitreal antivascular endothelial growth factor therapy in wet age-related macular disease. Case Rep Ophthalmol 2012 0.78
75 Cribriform-morular variant of papillary thyroid carcinoma displaying poorly differentiated features. Int J Surg Pathol 2013 0.78
76 Diagnostic criteria in well-differentiated thyroid carcinomas. Endocr Pathol 2006 0.78
77 Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. Cancer Lett 2005 0.77
78 Thyroid and parathyroid tumours in patients submitted to X-ray scalp epilation during the tinea capitis eradication campaign in the North of Portugal (1950-1963). Virchows Arch 2014 0.77
79 Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment. Eur J Endocrinol 2013 0.77
80 In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp. Endocr Relat Cancer 2011 0.77
81 GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells. PeerJ 2013 0.77
82 Molecular pathology of thyroid tumors: diagnostic and prognostic relevance. Int J Surg Pathol 2010 0.77
83 Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy. Expert Opin Ther Targets 2015 0.77
84 Increased lymphangiogenesis in Riedel thyroiditis (Immunoglobulin G4-related thyroid disease). Virchows Arch 2014 0.76
85 Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth. Hum Pathol 2008 0.76
86 Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR. Life Sci 2011 0.76
87 Poorly Differentiated and Undifferentiated Thyroid Carcinomas. Turk Patoloji Derg 2015 0.76
88 A founder SDHB mutation in Portuguese paraganglioma patients. Endocr Relat Cancer 2013 0.76
89 Alterations of the SDHD gene locus in midgut carcinoids. Genes Chromosomes Cancer 2003 0.76
90 Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex. Virchows Arch 2002 0.76
91 Re: Lohrer,H.D., Hieber,L. and Zitzelsberger,H. (2002) Differential mutation frequency in mitochondrial DNA from thyroid tumours. Carcinogenesis, 23, 1577-1582. Carcinogenesis 2003 0.75
92 Core I gene is overexpressed in Hürthle and non-Hürthle cell microfollicular adenomas and follicular carcinomas of the thyroid. BMC Cancer 2004 0.75
93 Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer. Exp Dermatol 2009 0.75
94 Molecular alterations in sporadic primary hyperparathyroidism. Genet Res Int 2011 0.75
95 Molecular Markers Involved in Tumorigenesis of Thyroid Carcinoma: Focus on Aggressive Histotypes. Cytogenet Genome Res 2017 0.75
96 Cystic tumor of the atrioventricular node of the heart appears to be the heart equivalent of the solid cell nests (ultimobranchial rests) of the thyroid. Am J Clin Pathol 2005 0.75
97 Hot topics in papillary thyroid carcinoma. Int J Surg Pathol 2010 0.75
98 Hobnail Variant of Papillary Thyroid Carcinoma: Clinicopathologic and Molecular Evidence of Progression to Undifferentiated Carcinoma in 2 Cases. Am J Surg Pathol 2017 0.75
99 Vascular invasion in thyroid and gastric carcinomas. Ultrastruct Pathol 2003 0.75
100 MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism. Eur J Endocrinol 2012 0.75
101 EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide. J Cell Biochem 2011 0.75
102 The familial counterparts of follicular cell--derived thyroid tumors. Int J Surg Pathol 2010 0.75