Published in J Cancer Res Clin Oncol on October 16, 2004
Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma. Clin Cancer Res (2008) 1.10
Glioblastoma multiforme therapy and mechanisms of resistance. Pharmaceuticals (Basel) (2013) 1.00
Classification and characterization of microsatellite instability across 18 cancer types. Nat Med (2016) 0.97
Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma. BMC Cancer (2006) 0.94
Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. PLoS One (2011) 0.89
The Changes in MGMT Promoter Methylation Status in Initial and Recurrent Glioblastomas. Transl Oncol (2012) 0.88
Alterations of p53, BCL-2, and hMSH2 protein expression in the normal brain tissues, gliosis, and gliomas. Int J Exp Pathol (2006) 0.87
Analysis of microsatellite instability in medulloblastoma. Neuro Oncol (2009) 0.87
Integrated analysis of mismatch repair system in malignant astrocytomas. PLoS One (2013) 0.82
Some speculation on the origin of glioblastoma. Neurosurg Rev (2006) 0.80
Beyond Genetics in Glioma Pathways: The Ever-Increasing Crosstalk between Epigenomic and Genomic Events. J Signal Transduct (2012) 0.78
Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade. Oncologist (2016) 0.78
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet (1997) 15.38
Microsatellite instability in cancer of the proximal colon. Science (1993) 14.51
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature (1993) 12.74
A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg (2001) 11.58
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet (1997) 10.71
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res (1997) 8.88
The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol (2002) 8.62
Cancer-susceptibility genes. Gatekeepers and caretakers. Nature (1997) 5.87
Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res (1997) 4.61
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res (1998) 3.36
Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res (1993) 2.65
Instability of short tandem repeats (microsatellites) in human cancers. Nat Genet (1994) 2.45
Mutations predisposing to hereditary nonpolyposis colorectal cancer. Adv Cancer Res (1997) 1.98
Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol (1993) 1.67
Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations. Cancer Res (1995) 1.57
Mismatch repair deficiency associated with overexpression of the MSH3 gene. Proc Natl Acad Sci U S A (1998) 1.56
Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. Br J Cancer (1994) 1.53
Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridization. Lab Invest (2001) 1.50
Molecular pathways in the formation of gliomas. Glia (1995) 1.43
p53 mutations and microsatellite instability in sporadic gastric cancer: when guardians fail. Cancer Res (1994) 1.42
Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors. Cancer Res (2001) 1.23
HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res (2000) 1.20
Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas. Cancer Res (1995) 1.14
Instability of microsatellites in human gliomas. Cancer Res (1995) 1.11
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Mol Cell Biol (1998) 1.11
A molecular genetic model of astrocytoma histopathology. Brain Pathol (1997) 1.07
Molecular genetic analysis of giant cell glioblastomas. Am J Pathol (1997) 1.06
Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue. J Neuropathol Exp Neurol (1995) 1.03
Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. Int J Cancer (2002) 0.99
Towards a molecular classification of colorectal cancer. Int J Colorectal Dis (1999) 0.99
Microsatellite instability and mutations of p53 and TGF-beta RII genes in gastric cancer. Hum Genet (1996) 0.95
Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers. Genes Chromosomes Cancer (2000) 0.91
Microsatellite instability analysis of primary human brain tumors. Oncogene (1996) 0.85
Infrequent hMSH2 mutations in sporadic gastric adenocarcinoma with microsatellite instability. Cancer Lett (1997) 0.81
Low frequency of replication errors in primary nervous system tumours. J Neurol Neurosurg Psychiatry (2000) 0.77
A microsatellite map of wheat. Genetics (1998) 5.21
Transmission of glioblastoma multiforme through liver transplantation. Lancet (1998) 2.33
Abundance, variability and chromosomal location of microsatellites in wheat. Mol Gen Genet (1995) 1.80
[German S3-guideline "Diagnosis and treatment of esophagogastric cancer"]. Z Gastroenterol (2011) 1.74
Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics. Am J Pathol (1997) 1.73
Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy. Br J Cancer (2007) 1.67
Microsatellite instability analysis: a multicenter study for reliability and quality control. Cancer Res (1997) 1.43
Genesis of cerebral aneurysms--an update. Acta Neurochir (Wien) (2001) 1.37
Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction. Proc Natl Acad Sci U S A (2002) 1.31
DHPLC mutation analysis of the hereditary nonpolyposis colon cancer (HNPCC) genes hMLH1 and hMSH2. J Biochem Biophys Methods (2001) 1.30
The biology of melanoma brain metastasis. Cancer Metastasis Rev (1999) 1.21
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins. Gene Ther (2000) 1.17
[Her2 testing in gastric cancer. What is different in comparison to breast cancer?]. Pathologe (2010) 1.14
ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma. Br J Cancer (2004) 1.11
bcl-2 expression, p53 accumulation, and apoptosis in ovarian carcinomas. Am J Clin Pathol (1996) 1.07
Gross total but not incomplete resection of glioblastoma prolongs survival in the era of radiochemotherapy. Ann Oncol (2013) 1.06
Liver-derived hepatitis C virus (HCV)-specific CD4(+) T cells recognize multiple HCV epitopes and produce interferon gamma. Hepatology (2000) 1.05
Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review. Am J Epidemiol (2009) 1.05
Molecular analysis of the PTEN, TP53 and CDKN2A tumor suppressor genes in long-term survivors of glioblastoma multiforme. J Neurooncol (2000) 1.04
A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. Ann Oncol (2008) 1.04
Association of RET protooncogene codon 45 polymorphism with Hirschsprung disease. Am J Hum Genet (1999) 1.04
Jet-cutting supported by high frequency current: new technique for hepatic surgery. World J Surg (1997) 1.02
Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer. Int J Cancer (2000) 1.02
Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: genetic reclassification and correlation with clinical features. Digestion (2004) 1.00
Expression of TRAIL and its receptors in human brain tumors. Biochem Biophys Res Commun (1999) 1.00
The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC). J Med Genet (2005) 0.99
Dietary iron enhances the tumor rate in dimethylhydrazine-induced colon carcinogenesis in mice. Cancer Lett (1988) 0.99
Cathepsin C gene variants in aggressive periodontitis. J Dent Res (2008) 0.99
[Molecular pathologic KRAS mutation analysis. A prerequisite of effective antibody treatment for metastasized colorectal cancer]. Chirurg (2008) 0.98
[Anastomotic ulcer following Whipple's operation with stomach preservation]. Zentralbl Chir (1982) 0.98
Primary aspergillosis of the sphenoid sinus with pituitary invasion - a rare differential diagnosis of sellar lesions. Acta Neurochir (Wien) (2006) 0.96
Angiogenesis, metastasis, and endogenous inhibition. J Neurooncol (2001) 0.95
Comparison of [18F]FHPG and [124/125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression. Eur J Nucl Med (2001) 0.93
An intronic germline transition in the HNPCC gene hMSH2 is associated with sporadic colorectal cancer. Eur J Cancer (1997) 0.92
The prostate stem cell antigen represents a novel glioma-associated antigen. Oncol Rep (2011) 0.92
Morphological detection of X- and Y-chromosomes in smears and paraffin-embedded tissues using a non-isotopic in situ hybridization technique (NISH). Int J Legal Med (1994) 0.91
Prognostic importance of the expression of CD44 splice variants in oral squamous cell carcinomas. Oral Oncol (1999) 0.91
Complementary therapy use in patients with glioma: an observational study. Neurology (2010) 0.91
Novel mutations in the cathepsin C gene in patients with pre-pubertal aggressive periodontitis and Papillon-Lefèvre syndrome. J Dent Res (2004) 0.90
Frequent loss of heterozygosity at the 19p13.3 locus without LKB1/STK11 mutations in human carcinoma metastases to the brain. J Neurooncol (2000) 0.90
Detection of colonic dysplasia by light-induced fluorescence endoscopy: a pilot study. Int J Colorectal Dis (1999) 0.90
The prognostic value of IDH mutations and MGMT promoter status in secondary high-grade gliomas. J Neurooncol (2012) 0.90
Malignant potential of cells isolated from lymph node or brain metastases of melanoma patients and implications for prognosis. Cancer Res (1991) 0.90
Infrequent genetic alterations of the tumor suppressor gene PTEN/MMAC1 in squamous cell carcinoma of the oral cavity. J Oral Pathol Med (2002) 0.90
Identification of uncommon chromosomal aberrations in the neuroglioma cell line H4 by spectral karyotyping. J Neurooncol (2001) 0.90
Genomic rearrangements of hMSH6 contribute to the genetic predisposition in suspected hereditary non-polyposis colorectal cancer syndrome. J Med Genet (2003) 0.89
A new system for cutting brain tissue preserving vessels: water jet cutting. Br J Neurosurg (1989) 0.88
Myomectomy as a pregnancy-preserving option in the carefully selected patient. Fetal Diagn Ther (2002) 0.88
Loss of heterozygosity accumulation in primary breast carcinomas and additionally in corresponding distant metastases is associated with poor outcome. Clin Cancer Res (1999) 0.87
Prognostic significance of apoptosis and associated factors in oral squamous cell carcinoma. Virchows Arch (2000) 0.87
Sixteen rare sequence variants of the hMLH1 and hMSH2 genes found in a cohort of 254 suspected HNPCC (hereditary non-polyposis colorectal cancer) patients: mutations or polymorphisms? Eur J Med Res (2001) 0.87
[Molecular pathology in hereditary colorectal cancer. Recommendations of the Collaborative German Study Group on hereditary colorectal cancer funded by the German Cancer Aid (Deutsche Krebshilfe)]. Pathologe (2004) 0.87
Combined molecular and clinical approaches for the identification of families with familial adenomatous polyposis coli. Ann Surg (1999) 0.86
Comparison of functional brain PET images and intraoperative brain-mapping data using image-guided surgery. Comput Aided Surg (2002) 0.86
Lack of association between endoglin intron 7 insertion polymorphism and intracranial aneurysms in a white population: evidence of racial/ethnic differences. Stroke (2001) 0.85
Knowledge retrieval as one type of knowledge-based decision support in medicine: results of an evaluation study. Int J Biomed Comput (1996) 0.85
An easy and safe method to store and disinfect explanted skull bone. Acta Neurochir (Wien) (1999) 0.85
Combined detection of CD44 isoforms by exon-specific RT-PCR and immunohistochemistry in primary human brain tumors and brain metastases. Biochem Biophys Res Commun (1996) 0.85
Inhibition of malignant glioma cell growth by a survivin mutant retrovirus. Hum Gene Ther (2005) 0.84
Monitoring gene therapy with cytosine deaminase: in vitro studies using tritiated-5-fluorocytosine. J Nucl Med (1996) 0.84
Bacteria: a major pathogenic factor for anastomotic insufficiency. Antimicrob Agents Chemother (1994) 0.84
Anti-angiogenic treatment strategies for malignant brain tumors. J Neurooncol (2001) 0.84
Combined molecular and clinical approach for decision making for surgery in HNPCC patients: a report on three cases in two families. Int J Colorectal Dis (2001) 0.83
Extramedullary blast crisis of chronic myeloid leukemia after allogeneic hematopoietic stem cell transplantation mimicking aggressive, translocation t(14;18)-positive B-cell lymphoma. Ann Hematol (2002) 0.83
Influence of dietary iron overload on cell proliferation and intestinal tumorigenesis in mice. Cancer Lett (1992) 0.83
Analysis of RET, ZEB2, EDN3 and GDNF genomic rearrangements in 80 patients with Hirschsprung disease (using multiplex ligation-dependent probe amplification). Ann Hum Genet (2009) 0.83
Rosette-forming glioneuronal tumor of the fourth ventricle in an elderly patient. J Neurooncol (2010) 0.83
[Prognostic factors in gallbladder carcinoma as a decision aid for reoperation]. Langenbecks Arch Chir Suppl Kongressbd (1997) 0.82
Genetic alterations of the tumor suppressor gene PTEN/MMAC1 in human brain metastases. Clin Cancer Res (1999) 0.82
The c-kit (CD117) sequence variation M541L, but not N564K, is frequent in the general population, and is not associated with CML in Caucasians. Leukemia (2006) 0.82
Molecular profiling of sporadic colorectal tumors by microsatellite analysis. Int J Oncol (2000) 0.82
NDRG1 prognosticates the natural course of disease in WHO grade II glioma. J Neurooncol (2014) 0.81
Accumulation of genetic alterations in brain metastases of sporadic breast carcinomas is associated with reduced survival after metastasis. Invasion Metastasis (2000) 0.81
Development of immunogenic colorectal cancer cell lines for vaccination: expression of CD80 (B7.1) is not sufficient to restore impaired primary T cell activation in vitro. Eur J Cancer (1995) 0.80
Association of germline mutations and polymorphisms of the RET proto-oncogene with idiopathic congenital central hypoventilation syndrome in 33 patients. J Med Genet (2003) 0.80
Combined use of narrow-band imaging magnification endoscopy and miniprobe confocal laser microscopy in neoplastic Barrett's esophagus. Endoscopy (2007) 0.80
Electroencephalogram silence ratio for early outcome prognosis in severe head trauma. Crit Care Med (2000) 0.80
Clinical consequences of molecular diagnosis in families with mismatch repair gene germline mutations. Int J Colorectal Dis (2000) 0.79
Hepatitis C virus-specific CD4+ T cell response after liver transplantation occurs early, is multispecific, compartmentalizes to the liver, and does not correlate with recurrent disease. J Infect Dis (2001) 0.79
Integration of intraoperative 3D-ultrasound in a commercial navigation system. Zentralbl Neurochir (2006) 0.79
Evidence that TSG101 aberrant transcripts are PCR artifacts. Biochem Biophys Res Commun (1998) 0.79
The diaphragma sellae meningioma -- a rare differential diagnosis of non-functioning pituitary adenoma. Zentralbl Neurochir (2004) 0.79
Prognostic factors and long-term results after surgery for gallbladder carcinoma: a retrospective study of 127 patients. Langenbecks Arch Surg (2001) 0.79