Published in J Cell Physiol on July 01, 2005
Structure, evolution, and biology of the MUC4 mucin. FASEB J (2007) 1.75
Assay of mucins in human tear fluid. Exp Eye Res (2007) 1.44
Differentiation markers in pancreatic head adenocarcinomas: MUC1 and MUC4 expression indicates poor prognosis in pancreatobiliary differentiated tumours. Histopathology (2009) 1.17
MUC4 and MUC1 expression in adenocarcinoma of the stomach correlates with vessel invasion and lymph node metastasis: an immunohistochemical study of early gastric cancer. PLoS One (2012) 1.09
MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer. Br J Cancer (2008) 0.88
IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling. Respir Res (2006) 0.88
Human milk glycoproteins protect infants against human pathogens. Breastfeed Med (2013) 0.87
The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells. Breast Cancer Res (2009) 0.87
Expression of MUC4 mucin is observed mainly in the intestinal type of intraductal papillary mucinous neoplasm of the pancreas. Pancreas (2013) 0.86
Development of human minor salivary glands: expression of mucins according to stage of morphogenesis. J Anat (2011) 0.77
Mucus and Mucins: do they have a role in the inhibition of the human immunodeficiency virus? Virol J (2017) 0.75
Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. Lancet Oncol (2010) 5.65
Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells. Cancer Res (2008) 2.65
Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line. Cancer Res (2005) 2.39
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases. J Biol Chem (2004) 2.36
Vascular endothelial growth factor polymorphisms in gastric cancer development, prognosis, and survival. J Surg Oncol (2006) 1.80
Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer. Cancer Res (2008) 1.59
Characterization of CD44v3-containing isoforms in head and neck cancer. Cancer Biol Ther (2006) 1.58
LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy. Mol Cell Biol (2006) 1.55
Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8. Mol Cell Biol (2004) 1.54
An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels. Proc Natl Acad Sci U S A (2002) 1.52
Cell signaling through membrane mucins. Bioessays (2003) 1.51
Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1. Mol Cell Biol (2007) 1.50
Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance. Int J Cancer (2002) 1.50
Genetic dissection of drought tolerance in chickpea (Cicer arietinum L.). Theor Appl Genet (2013) 1.40
The mucin Muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3. J Biol Chem (2006) 1.31
Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth. Cancer Res (2006) 1.30
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, in cancer and epithelia: to protect and to survive. Prog Nucleic Acid Res Mol Biol (2002) 1.29
Serum IL-6, TNFalpha and CRP levels in Greek colorectal cancer patients: prognostic implications. World J Gastroenterol (2005) 1.28
Circulating MicroRNA in inflammatory bowel disease. J Crohns Colitis (2012) 1.24
Soluble CD44 is a potential marker for the early detection of head and neck cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.22
Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis. Development (2002) 1.22
Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation. J Biol Chem (2002) 1.21
The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms. Cancer Res (2009) 1.20
Identification of 14-3-3epsilon substrates from embryonic murine brain. J Proteome Res (2006) 1.15
Muc4-ErbB2 complex formation and signaling in polarized CACO-2 epithelial cells indicate that Muc4 acts as an unorthodox ligand for ErbB2. Mol Biol Cell (2006) 1.11
MUC4 and ErbB2 expression in squamous cell carcinoma of the upper aerodigestive tract: correlation with clinical outcomes. Laryngoscope (2004) 1.09
Role of neuregulin-1 beta in the developing lung. Am J Respir Crit Care Med (2003) 1.08
Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer. Mol Cancer Res (2011) 1.08
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells. J Biol Chem (2003) 1.07
Survivin -31G/C promoter polymorphism and sporadic colorectal cancer. Int J Colorectal Dis (2008) 1.07
Salivary soluble CD44: a potential molecular marker for head and neck cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.06
Micro-RNAs as regulators and possible diagnostic bio-markers in inflammatory bowel disease. J Crohns Colitis (2011) 1.04
Vascular endothelial growth factor and endoglin (CD-105) in gastric cancer. Gastric Cancer (2007) 1.03
MUC4 interacts with ErbB2 in human gallbladder carcinoma: potential pathobiological implications. Eur J Cancer (2008) 1.03
The human mucin MUC4 is transcriptionally regulated by caudal-related homeobox, hepatocyte nuclear factors, forkhead box A, and GATA endodermal transcription factors in epithelial cancer cells. J Biol Chem (2007) 1.03
Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival. Mol Carcinog (2009) 1.02
Molecular signaling in the regulation of mucins. J Cell Biochem (2007) 1.01
Distant solitary skeletal muscle metastasis from papillary thyroid carcinoma. Int Surg (2007) 0.99
Mechanisms of ErbB receptor negative regulation and relevance in cancer. Exp Cell Res (2008) 0.99
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
Connective tissue growth factor antibody therapy attenuates hyperoxia-induced lung injury in neonatal rats. Am J Respir Cell Mol Biol (2011) 0.98
Quantity control of the ErbB3 receptor tyrosine kinase at the endoplasmic reticulum. Mol Cell Biol (2011) 0.98
CTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol (2011) 0.97
Association between mutations in the CARD15/NOD2 gene and colorectal cancer in a Greek population. Int J Cancer (2005) 0.97
Genetic susceptibility to pancreatic cancer and its functional characterisation: the PANcreatic Disease ReseArch (PANDoRA) consortium. Dig Liver Dis (2012) 0.95
Stem cells in colon cancer. A new era in cancer theory begins. Int J Colorectal Dis (2010) 0.95
Neutrophil elastase increases MUC4 expression in normal human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol (2002) 0.95
Muc4/MUC4 functions and regulation in cancer. Future Oncol (2009) 0.95
Multidrug resistance correlates with overexpression of Muc4 but inversely with P-glycoprotein and multidrug resistance related protein in transfected human melanoma cells. Biochem Pharmacol (2003) 0.95
Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice. Lab Invest (2008) 0.95
Transanal polypectomy using single incision laparoscopic instruments. World J Gastrointest Surg (2011) 0.92
ErbB receptor negative regulatory mechanisms: implications in cancer. J Mammary Gland Biol Neoplasia (2006) 0.92
CD44 interacts with EGFR and promotes head and neck squamous cell carcinoma initiation and progression. Oral Oncol (2012) 0.91
5-Benzylglycinyl-amiloride kills proliferating and nonproliferating malignant glioma cells through caspase-independent necroptosis mediated by apoptosis-inducing factor. J Pharmacol Exp Ther (2012) 0.91
Synthesis and secretion of Muc4/sialomucin complex: implication of intracellular proteolysis. Biochem J (2002) 0.91
SMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cells. J Biol Chem (2003) 0.91
Mucinous tubular and spindle cell carcinoma of the kidney: a case report. Case Rep Oncol (2012) 0.91
Expression, location, and interactions of ErbB2 and its intramembrane ligand Muc4 (sialomucin complex) in rat mammary gland during pregnancy. J Cell Physiol (2005) 0.91
Targeting glycogen synthase kinase-3β to prevent hyperoxia-induced lung injury in neonatal rats. Am J Respir Cell Mol Biol (2013) 0.90
Association of the miR-146aC>G, miR-149T>C, and miR-196a2T>C polymorphisms with gastric cancer risk and survival in the Greek population. Mol Biol Rep (2013) 0.90
Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells. Cancer Res (2010) 0.90
HSP90, HSPA8, HIF-1 alpha and HSP70-2 polymorphisms in breast cancer: a case-control study. Mol Biol Rep (2012) 0.88
Non-apoptotic desquamation of cells from corneal epithelium: putative role for Muc4/sialomucin complex in cell release and survival. J Cell Physiol (2005) 0.88
Membrane mucin Muc4 induces density-dependent changes in ERK activation in mammary epithelial and tumor cells: role in reversal of contact inhibition. J Biol Chem (2006) 0.88
MUC4 and ERBB2 expression in major and minor salivary gland mucoepidermoid carcinoma. Head Neck (2004) 0.88
The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells. Breast Cancer Res (2009) 0.87
Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8. J Biol Chem (2010) 0.87
Expression of clock genes in patients with colorectal cancer. Int J Biol Markers (2013) 0.86
Sequestration and segregation of receptor kinases in epithelial cells: implications for ErbB2 oncogenesis. Sci STKE (2007) 0.86
Adjuvant chemotherapy in rectal cancer: defining subgroups who may benefit after neoadjuvant chemoradiation and resection: a pooled analysis of 3,313 patients. Int J Cancer (2014) 0.86
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors. J Biol Chem (2010) 0.86
Systemic inflammatory response after laparoscopic and conventional colectomy for cancer: a matched case-control study. Surg Endosc (2011) 0.85
Salivary markers and risk factor data: a multivariate modeling approach for head and neck squamous cell carcinoma detection. Cancer Biomark (2011) 0.85
Association of the clock genes polymorphisms with colorectal cancer susceptibility. J Surg Oncol (2013) 0.85
The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells. Mol Cancer Ther (2012) 0.85
A cell-permeant amiloride derivative induces caspase-independent, AIF-mediated programmed necrotic death of breast cancer cells. PLoS One (2013) 0.84
Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions. BMC Cancer (2010) 0.84
MUC4 involvement in ErbB2/ErbB3 phosphorylation and signaling in response to airway cell mechanical injury. J Cell Biochem (2009) 0.84
PEA3 transactivates the Muc4/sialomucin complex promoter in mammary epithelial and tumor cells. J Biol Chem (2003) 0.84
Vascular endothelial growth factor and endoglin expression in colorectal cancer. J Cancer Res Clin Oncol (2009) 0.84
Mechanistic and signaling analysis of Muc4-ErbB2 signaling module: new insights into the mechanism of ligand-independent ErbB2 activity. J Cell Physiol (2010) 0.83
Expression and localization of Muc4/sialomucin complex (SMC) in the adult and developing rat intestine: implications for Muc4/SMC function. J Cell Physiol (2005) 0.83
TGFbeta regulation of membrane mucin Muc4 via proteosome degradation. J Cell Biochem (2009) 0.83
MUC4 expression and localization in gastrointestinal tract and skin of human embryos. Tissue Cell (2006) 0.83
Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer. Gastric Cancer (2011) 0.83
An ErbB2-Muc4 complex in rat ocular surface epithelia. Curr Eye Res (2002) 0.83
Complications of percutaneous stereotactic vacuum assisted breast biopsy system utilizing radio frequency. Eur J Radiol (2012) 0.82