Published in Development on January 26, 2005
Axon guidance molecules in vascular patterning. Cold Spring Harb Perspect Biol (2010) 2.37
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells. PLoS One (2008) 1.66
Notch signaling in the vasculature. Curr Top Dev Biol (2010) 1.62
Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor. Cell Stem Cell (2014) 1.56
Roles for VEGF in the adult. Microvasc Res (2007) 1.48
Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron (2013) 1.47
The hypothalamic neuropeptide oxytocin is required for formation of the neurovascular interface of the pituitary. Dev Cell (2011) 1.46
Selective requirements for NRP1 ligands during neurovascular patterning. Development (2007) 1.41
Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity. Oncotarget (2012) 1.37
Peripheral nerve-derived CXCL12 and VEGF-A regulate the patterning of arterial vessel branching in developing limb skin. Dev Cell (2013) 1.35
Regulation of cavernous nerve injury-induced apoptosis by sonic hedgehog. Biol Reprod (2006) 1.17
VEGF in the nervous system. Organogenesis (2010) 1.13
Specification of arterial, venous, and lymphatic endothelial cells during embryonic development. Histol Histopathol (2010) 1.12
Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation. Circ Res (2012) 1.12
Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer. Cell Res (2011) 1.06
VEGF-directed blood vessel patterning: from cells to organism. Cold Spring Harb Perspect Med (2012) 1.05
Arteries are formed by vein-derived endothelial tip cells. Nat Commun (2014) 1.04
Transcriptional regulation of endothelial cell and vascular development. Circ Res (2013) 1.03
Brothers and sisters: molecular insights into arterial-venous heterogeneity. Circ Res (2008) 1.03
TGFβ signaling is required for sprouting lymphangiogenesis during lymphatic network development in the skin. Development (2013) 1.03
Neuronal control of metabolism through nutrient-dependent modulation of tracheal branching. Cell (2014) 0.99
Role of crosstalk between phosphatidylinositol 3-kinase and extracellular signal-regulated kinase/mitogen-activated protein kinase pathways in artery-vein specification. Circ Res (2008) 0.99
Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli. BMC Dev Biol (2008) 0.99
Endothelial differentiation: molecular mechanisms of specification and heterogeneity. Arterioscler Thromb Vasc Biol (2011) 0.98
New insights on Schwann cell development. Glia (2015) 0.95
Cutaneous manipulation of vascular growth factors leads to alterations in immunocytes, blood vessels and nerves: Evidence for a cutaneous neurovascular unit. J Dermatol Sci (2010) 0.93
Motoneurons are essential for vascular pathfinding. Development (2011) 0.93
Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol (2013) 0.92
Molecular controls of arterial morphogenesis. Circ Res (2015) 0.91
Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations. Hum Mol Genet (2011) 0.91
Neuronal action on the developing blood vessel pattern. Semin Cell Dev Biol (2011) 0.90
VEGF receptor signaling in vertebrate development. Organogenesis (2010) 0.87
Whole-mount immunohistochemical analysis for embryonic limb skin vasculature: a model system to study vascular branching morphogenesis in embryo. J Vis Exp (2011) 0.87
In vivo evolution of tumor-derived endothelial cells. PLoS One (2012) 0.86
Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability. Microcirculation (2014) 0.85
Nerve growth factor regulates neurolymphatic remodeling during corneal inflammation and resolution. PLoS One (2014) 0.85
A proposed role for VEGF isoforms in sex-specific vasculature development in the gonad. Reprod Domest Anim (2008) 0.85
Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development (2014) 0.84
Genetic and epigenetic mechanisms in the early development of the vascular system. J Anat (2006) 0.84
SIV-induced impairment of neurovascular repair: a potential role for VEGF. J Neurovirol (2012) 0.83
Branching morphogenesis: from cells to organs and back. Cold Spring Harb Perspect Biol (2012) 0.81
κ Opioid receptor ligands regulate angiogenesis in development and in tumours. Br J Pharmacol (2014) 0.81
A method for labeling vasculature in embryonic mice. J Vis Exp (2011) 0.81
Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus. PLoS One (2013) 0.80
Adrenomedullin as a growth and cell fate regulatory factor for adult neural stem cells. Stem Cells Int (2012) 0.79
CXCL12 Signaling Is Essential for Maturation of the Ventricular Coronary Endothelial Plexus and Establishment of Functional Coronary Circulation. Dev Cell (2015) 0.78
Differentiation state determines neural effects on microvascular endothelial cells. Exp Cell Res (2012) 0.78
Tissue-specific venous expression of the EPH family receptor EphB1 in the skin vasculature. Dev Dyn (2013) 0.78
Class 3 semaphorins negatively regulate dermal lymphatic network formation. Biol Open (2015) 0.78
Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization. Nat Commun (2017) 0.78
Interplay of neuropilin-1 and semaphorin 3A after partial hepatectomy in rats. World J Gastroenterol (2012) 0.77
In vivo time-lapse imaging reveals extensive neural crest and endothelial cell interactions during neural crest migration and formation of the dorsal root and sympathetic ganglia. Dev Biol (2016) 0.76
NRP-1 Receptor Expression Mismatch in Skin of Subjects with Experimental and Diabetic Small Fiber Neuropathy. PLoS One (2016) 0.76
The Nervous System Orchestrates and Integrates Craniofacial Development: A Review. Front Physiol (2016) 0.76
Heterogeneity and Developmental Connections between Cell Types Inhabiting Teeth. Front Physiol (2017) 0.75
Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature. Cell Rep (2017) 0.75
Denervation in Femoral Artery-Ligated Hindlimbs Diminishes Ischemic Recovery Primarily via Impaired Arteriogenesis. PLoS One (2016) 0.75
Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells. PLoS One (2015) 0.75
Age-related morphological regression of myelinated fibers and capillary architecture of distal peripheral nerves in rats. BMC Neurosci (2016) 0.75
Genetic and epigenetic mechanisms in the development of arteriovenous malformations in the brain. Clin Epigenetics (2016) 0.75
Vessel-dependent recruitment of sympathetic axons: looking for innervation in all the right places. J Clin Invest (2014) 0.75
Nerve control of blood vessel patterning. Dev Cell (2013) 0.75
Novel roles of perivascular nerves on neovascularization. Neurol Sci (2014) 0.75
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med (2004) 49.02
The biology of VEGF and its receptors. Nat Med (2003) 32.13
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov (2004) 9.96
VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med (2008) 9.87
HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 9.12
Autocrine VEGF signaling is required for vascular homeostasis. Cell (2007) 7.37
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat Biotechnol (2007) 6.76
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest (2003) 6.44
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell (2002) 5.35
Corneal avascularity is due to soluble VEGF receptor-1. Nature (2006) 4.77
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1. Science (2003) 4.56
A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila. Nature (2004) 4.52
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron (2007) 4.47
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci U S A (2002) 4.46
Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature (2010) 4.34
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature (2002) 4.10
Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci U S A (2009) 3.98
Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. Cell (2009) 3.97
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst (2007) 3.95
Automated monitoring and analysis of social behavior in Drosophila. Nat Methods (2009) 3.94
The hypoxic response of tumors is dependent on their microenvironment. Cancer Cell (2003) 3.89
Functional identification of an aggression locus in the mouse hypothalamus. Nature (2011) 3.88
Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell (2002) 3.84
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell (2009) 3.71
Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature (2007) 3.70
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest (2002) 3.70
Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron (2005) 3.54
Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF. J Biol Chem (2005) 3.30
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell (2004) 3.28
Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron (2003) 3.27
VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis. Cancer Cell (2002) 3.27
Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus. Neuron (2005) 3.21
Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags. Proc Natl Acad Sci U S A (2002) 3.15
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. Dev Cell (2006) 3.10
The molecular basis of vascular lumen formation in the developing mouse aorta. Dev Cell (2009) 3.08
Allocrine modulation of feeding behavior by the Sex Peptide of Drosophila. Curr Biol (2006) 3.01
Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res (2005) 3.00
An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy. Nat Med (2013) 3.00
SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron (2003) 2.98
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc Natl Acad Sci U S A (2009) 2.96
Targeting the tumour vasculature: insights from physiological angiogenesis. Nat Rev Cancer (2010) 2.93
Developmental and pathological angiogenesis. Annu Rev Cell Dev Biol (2011) 2.83
Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes. Proc Natl Acad Sci U S A (2010) 2.77
Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res (2006) 2.75
G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc Natl Acad Sci U S A (2009) 2.68
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell (2013) 2.64
Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development. Cell (2010) 2.64
Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation. J Clin Invest (2012) 2.58
Role of VEGF-A in vascularization of pancreatic islets. Curr Biol (2003) 2.56
VEGFA is necessary for chondrocyte survival during bone development. Development (2004) 2.54
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics (2005) 2.50
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function. Am J Pathol (2005) 2.38
Distinct sensory representations of wind and near-field sound in the Drosophila brain. Nature (2009) 2.32
An anatomic gene expression atlas of the adult mouse brain. Nat Neurosci (2009) 2.30
Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression. Proc Natl Acad Sci U S A (2008) 2.30
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling. Dev Biol (2003) 2.24
VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis. EMBO J (2004) 2.22
Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J (2012) 2.21
Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Genes Dev (2002) 2.19
Two different forms of arousal in Drosophila are oppositely regulated by the dopamine D1 receptor ortholog DopR via distinct neural circuits. Neuron (2009) 2.18
The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Neuron (2006) 2.18
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol (2006) 2.10
Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells. Cancer Res (2008) 2.08
Development and evaluation of a micro- and nanoscale proteomic sample preparation method. J Proteome Res (2005) 2.06
Development of NG2 neural progenitor cells requires Olig gene function. Proc Natl Acad Sci U S A (2006) 2.04
ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo. J Biol Chem (2002) 2.02
BCR-ABL1 compound mutations in tyrosine kinase inhibitor-resistant CML: frequency and clonal relationships. Blood (2012) 2.01
Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells. Development (2004) 1.98
A direct and melanopsin-dependent fetal light response regulates mouse eye development. Nature (2013) 1.98
Identification of an aggression-promoting pheromone and its receptor neurons in Drosophila. Nature (2009) 1.96
Reversible silencing of neuronal excitability in behaving mice by a genetically targeted, ivermectin-gated Cl- channel. Neuron (2007) 1.95
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature (2011) 1.91
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease. J Clin Invest (2012) 1.90
Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proc Natl Acad Sci U S A (2003) 1.90
Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron (2005) 1.89
Cardiovascular ephrinB2 function is essential for embryonic angiogenesis. Development (2002) 1.84
Light activation of an innate olfactory avoidance response in Drosophila. Curr Biol (2007) 1.81
Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development (2005) 1.81
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell (2008) 1.79
Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell (2012) 1.79
The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells. Proc Natl Acad Sci U S A (2003) 1.78
Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nat Neurosci (2007) 1.78
A general approach to site-specific antibody drug conjugates. Proc Natl Acad Sci U S A (2014) 1.77
VEGF inhibition: insights from preclinical and clinical studies. Cell Tissue Res (2008) 1.76
PlGF blockade does not inhibit angiogenesis during primary tumor growth. Cell (2010) 1.75
Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization. Proc Natl Acad Sci U S A (2004) 1.75