Nasser H Zawia

Author PubWeight™ 25.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J Neurosci 2008 1.92
2 The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain. J Neurosci 2005 1.46
3 Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain. FASEB J 2006 1.22
4 How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD. Curr Alzheimer Res 2007 1.15
5 Gene expression profiles in the cerebellum and hippocampus following exposure to a neurotoxicant, Aroclor 1254: developmental effects. Toxicol Appl Pharmacol 2008 1.11
6 Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer's disease. J Alzheimers Dis 2011 1.06
7 Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to aging. Mech Ageing Dev 2012 1.03
8 The environment, epigenetics and amyloidogenesis. J Mol Neurosci 2007 1.03
9 In vitro Pb exposure disturbs the balance between Aβ production and elimination: the role of AβPP and neprilysin. Neurotoxicology 2011 0.92
10 Epigenetics: a novel therapeutic approach for the treatment of Alzheimer's disease. Pharmacol Ther 2013 0.90
11 Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice. J Alzheimers Dis 2009 0.89
12 Early-life events may trigger biochemical pathways for Alzheimer's disease: the "LEARn" model. Biogerontology 2008 0.88
13 Enhanced taupathy and AD-like pathology in aged primate brains decades after infantile exposure to lead (Pb). Neurotoxicology 2013 0.87
14 Integration of genome-wide expression and methylation data: relevance to aging and Alzheimer's disease. Neurotoxicology 2012 0.87
15 Alzheimer's disease biomarkers and epigenetic intermediates following exposure to Pb in vitro. Curr Alzheimer Res 2012 0.87
16 Environmental and dietary risk factors in Alzheimer's disease. Expert Rev Neurother 2007 0.86
17 Transplacental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the temporal modulation of Sp1 DNA binding in the developing cerebral cortex and cerebellum. Exp Toxicol Pathol 2002 0.84
18 The ability of tolfenamic acid to penetrate the brain: a model for testing the brain disposition of candidate Alzheimer's drugs using multiple platforms. Curr Alzheimer Res 2011 0.83
19 Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis. J Alzheimers Dis 2008 0.83
20 Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm. Curr Alzheimer Res 2012 0.83
21 Lead exposure: expression and activity levels of Oct-2 in the developing rat brain. Toxicol Sci 2006 0.80
22 Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice. Neurobiol Aging 2013 0.80
23 Cellular and organismal toxicity of the anti-cancer small molecule, tolfenamic acid: a pre-clinical evaluation. Cell Physiol Biochem 2013 0.79
24 Ontogenetic alterations in prototypical transcription factors in the rat cerebellum and hippocampus following perinatal exposure to a commercial PCB mixture. Neurotoxicology 2005 0.78
25 Characterization of nigerlysin, hemolysin produced by Aspergillus niger, and effect on mouse neuronal cells in vitro. Toxicology 2005 0.77
26 Tolfenamic acid reduces tau and CDK5 levels: implications for dementia and tauopathies. J Neurochem 2014 0.75
27 An initial animal proof-of-concept study for central administration of clozapine to schizophrenia patients. Schizophr Res 2008 0.75