TCDD causes suppression of growth and differentiation of MCF10A, human mammary epithelial cells by interfering with their insulin receptor signaling through c-Src kinase and ERK activation.

PubWeight™: 0.86‹?›

🔗 View Article (PMID 15674848)

Published in J Biochem Mol Toxicol on January 01, 2004

Authors

Sujin Park1, Olga Mazina, Akira Kitagawa, Patrick Wong, Fumio Matsumura

Author Affiliations

1: Department of Environmental Toxicology and the Center for Environmental Health Sciences, University of California, Davis, CA 95616, USA.

Articles by these authors

Ultrasound-guided popliteal block through a common paraneural sheath versus conventional injection: a prospective, randomized, double-blind study. Reg Anesth Pain Med (2013) 3.37

Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol (2004) 3.03

ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol (2005) 2.50

Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II. Mol Biol Cell (2003) 2.17

Alteration of gene expression in normal-appearing colon mucosa of APC(min) mice and human cancer patients. Cancer Res (2004) 1.95

RelB, a new partner of aryl hydrocarbon receptor-mediated transcription. Mol Endocrinol (2007) 1.95

Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun (2008) 1.89

The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway. J Cell Biol (2002) 1.86

Activation of aryl hydrocarbon receptor induces vascular inflammation and promotes atherosclerosis in apolipoprotein E-/- mice. Arterioscler Thromb Vasc Biol (2011) 1.75

A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows. J Cell Biol (2002) 1.53

Specification of actin filament function and molecular composition by tropomyosin isoforms. Mol Biol Cell (2003) 1.51

Induction of proinflammatory cytokines and C-reactive protein in human macrophage cell line U937 exposed to air pollution particulates. Environ Health Perspect (2005) 1.50

A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem Pharmacol (2008) 1.44

Standard-dose statin therapy provides incremental clinical benefits in normocholesterolemic diabetic patients. Circ J (2010) 1.39

Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1. Dev Cell (2008) 1.38

Dioxin increases C/EBPbeta transcription by activating cAMP/protein kinase A. J Biol Chem (2003) 1.33

Involvement of RelB in aryl hydrocarbon receptor-mediated induction of chemokines. Biochem Biophys Res Commun (2007) 1.30

Modulation of the chemokines KC and MCP-1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice. Arch Biochem Biophys (2007) 1.18

Molecular epidemiologic evidence for diabetogenic effects of dioxin exposure in U.S. Air force veterans of the Vietnam war. Environ Health Perspect (2006) 1.17

Langerhans cell histiocytosis immunohistochemical expression of fascin, a dendritic cell marker. Am J Clin Pathol (2002) 1.15

Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1). Genes Cells (2006) 1.12

Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein. J Mol Biol (2010) 1.12

How to minimize inappropriate utilization of Accident and Emergency Departments: improve the validity of classifying the general practice cases amongst the A&E attendees. Health Policy (2003) 1.10

Caldesmon inhibits Arp2/3-mediated actin nucleation. J Biol Chem (2003) 1.08

Activation of inflammatory mediators and potential role of ah-receptor ligands in foam cell formation. Cardiovasc Toxicol (2004) 1.08

Relating structure to function: Heschl's gyrus and acoustic processing. J Neurosci (2009) 1.07

Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression. Am J Pathol (2007) 1.06

Chromosomal variability of human mesenchymal stem cells cultured under hypoxic conditions. J Cell Mol Med (2012) 1.05

Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle. Mol Biol Cell (2009) 1.04

Altered gene expression in normal colonic mucosa of individuals with polyps of the colon. Dis Colon Rectum (2005) 1.03

Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle. J Biol Chem (2008) 0.97

Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin. Toxicol Appl Pharmacol (2008) 0.97

Fascin1 promotes cell migration of mature dendritic cells. J Immunol (2011) 0.95

Fascin1 is dispensable for mouse development but is favorable for neonatal survival. Cell Motil Cytoskeleton (2009) 0.95

Dehydroepiandrosterone supplementation improves endothelial function and insulin sensitivity in men. J Clin Endocrinol Metab (2003) 0.95

Significance of the sulfonylurea receptor (SUR) as the target of diflubenzuron in chitin synthesis inhibition in Drosophila melanogaster and Blattella germanica. Insect Biochem Mol Biol (2004) 0.94

How color enhances visual memory for natural scenes. Psychol Sci (2006) 0.94

Rac-induced increase of phosphorylation of myosin regulatory light chain in HeLa cells. Cell Motil Cytoskeleton (2004) 0.94

Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A. Toxicology (2005) 0.94

Arylhydrocarbon receptor activation in NCI-H441 cells and C57BL/6 mice: possible mechanisms for lung dysfunction. Am J Respir Cell Mol Biol (2009) 0.94

Effects of early statin treatment on symptomatic heart failure and ischemic events after acute myocardial infarction in Japanese. Am J Cardiol (2006) 0.94

Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells. Mol Pharmacol (2008) 0.93

Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with induced adipocyte differentiation in mouse embryonic fibroblasts (MEFs) involves tyrosine kinase c-Src. Biochem Pharmacol (2003) 0.92

Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. Biochemistry (2008) 0.92

Rapid activation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of Ah receptor signaling in MCF10A cells. Biochemistry (2007) 0.92

Long-term exposure to beta-hexachlorocyclohexane (beta-HCH) promotes transformation and invasiveness of MCF-7 human breast cancer cells. Biochem Pharmacol (2003) 0.91

Alteration of gene expression in macroscopically normal colonic mucosa from individuals with a family history of sporadic colon cancer. Clin Cancer Res (2005) 0.90

FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor. Biochim Biophys Acta (2010) 0.90

TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys. Biochem Pharmacol (2009) 0.89

Interaction of aryl hydrocarbon receptor and NF-κB subunit RelB in breast cancer is associated with interleukin-8 overexpression. Arch Biochem Biophys (2011) 0.89

Effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane (p,p'-DDT) on 3T3-L1 and 3T3-F442A adipocyte differentiation. Biochem Pharmacol (2002) 0.89

Usefulness of hydrophilic vs lipophilic statins after acute myocardial infarction: subanalysis of MUSASHI-AMI. Circ J (2007) 0.89

Increased collaboration between primary care and psychiatric services. A survey of general practitioners' views and referrals. Aust Fam Physician (2002) 0.88

Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. Toxicology (2011) 0.87

TCDD induced pericardial edema and relative COX-2 expression in medaka (Oryzias Latipes) embryos. Toxicol Sci (2010) 0.87

Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR). BMC Cancer (2009) 0.87

Development of a human adipocyte model derived from human mesenchymal stem cells (hMSC) as a tool for toxicological studies on the action of TCDD. Biol Chem (2008) 0.86

The use of c-src knockout mice for the identification of the main toxic signaling pathway of TCDD to induce wasting syndrome. J Biochem Mol Toxicol (2003) 0.86

Polychlorinated biphenyls and toxaphene in Pacific tree frog tadpoles (Hyla regilla) from the California Sierra Nevada, USA. Environ Toxicol Chem (2002) 0.85

Comparison of the characteristic of estrogenic action patterns of beta-HCH and heregulin beta1 in MCF-7 human breast cancer cells. J Biochem Mol Toxicol (2002) 0.85

Non-genomic action of TCDD to induce inflammatory responses in HepG2 human hepatoma cells and in liver of C57BL/6J mice. Biol Chem (2010) 0.85

Solubilized gramicidin A as potential systemic antibiotics. Chembiochem (2011) 0.85

Sex differences of risk factors for acute myocardial infarction in Japanese patients. Circ J (2006) 0.84

Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages. Chemosphere (2009) 0.84

Preventive effect of neutropenia on carbon tetrachloride-induced hepatotoxicity in rats. J Appl Toxicol (2006) 0.84

TCDD suppresses insulin-responsive glucose transporter (GLUT-4) gene expression through C/EBP nuclear transcription factors in 3T3-L1 adipocytes. J Biochem Mol Toxicol (2006) 0.84

AhR deficiency impairs expression of LPS-induced inflammatory genes in mice. Biochem Biophys Res Commun (2011) 0.84

Synthesis, 3D-QSAR, and docking studies of 1-phenyl-1H-1,2,3-triazoles as selective antagonists for beta3 over alpha1beta2gamma2 GABA receptors. Bioorg Med Chem (2007) 0.83

Preventive effect of teprenone on acute gastric mucosal lesion progression in compound 48/80-treated rats. Eur J Pharmacol (2004) 0.83

Synthesis and structure-activity relationships of 1-phenyl-1H-1,2,3-triazoles as selective insect GABA receptor antagonists. J Agric Food Chem (2006) 0.83

A four-week walking exercise programme in patients with knee osteoarthritis improves the ability of dual-task performance: a randomized controlled trial. Clin Rehabil (2011) 0.83

The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells. Mol Endocrinol (2009) 0.83

Serum free BG-1 cell proliferation assay: a sensitive method for determining organochlorine pesticide estrogen receptor activation at the nanomolar range. Toxicol In Vitro (2005) 0.82

Evidence behind the WHO guidelines: hospital care for children: what is the role of prophylactic antibiotics in the management of burns? J Trop Pediatr (2009) 0.82

Melatonin prevents disruption of hepatic reactive oxygen species metabolism in rats treated with carbon tetrachloride. J Pineal Res (2004) 0.82

Development of oxidative stress and cell damage in the liver of rats with water-immersion restraint stress. Redox Rep (2007) 0.82

Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages. Arch Biochem Biophys (2008) 0.82

Distribution of polychlorinated biphenyls and chlorinated pesticide residues in trout in the Sierra Nevada. J Environ Qual (2004) 0.82

Studies on the cell treatment conditions to elicit lipolytic responses from 3T3-L1 adipocytes to TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Cell Biochem (2007) 0.81

Facile synthesis of tetrafluorotyrosine and its application in pH triggered membrane lysis. Org Lett (2010) 0.81

Octacosanol attenuates disrupted hepatic reactive oxygen species metabolism associated with acute liver injury progression in rats intoxicated with carbon tetrachloride. J Clin Biochem Nutr (2008) 0.81

Effects of src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-src knockout mice procured through six generations of backcrossings to C57BL/6 mice. Toxicology (2002) 0.81

Biological functions of the arylhydrocarbon receptor: beyond induction of cytochrome P450s. Introduction to this special issue. Biochem Pharmacol (2008) 0.81

Selective activation of NF-kappaB and E2F by low concentration of arsenite in U937 human monocytic leukemia cells. J Biochem Mol Toxicol (2008) 0.81

Health-related quality of life, disease severity, and anticipated trajectory of diabetes. Diabetes Educ (2012) 0.81

IL-22 mRNA expression in blood samples as a useful biomarker for assessing the adverse health effects of PCBs on allergic children. Int J Environ Res Public Health (2012) 0.81

Evidence that "brain-specific" FOX-1, FOX-2, and nPTB alternatively spliced isoforms are produced in the lens. Curr Eye Res (2011) 0.81

Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin. J Biol Chem (2002) 0.81

Morning home blood pressure may be a significant marker of nephropathy in Japanese patients with type 2 diabetes: ADVANCED-J study 1. Hypertens Res (2009) 0.81

Levels of the adipocyte-derived plasma protein, adiponectin, have a close relationship with atheroma. Thromb Res (2005) 0.80

Adiponectin is inversely related to plasminogen activator inhibitor type 1 in patients with stable exertional angina. Thromb Haemost (2004) 0.80

Promotion of breast cancer by beta-hexachlorocyclohexane in MCF10AT1 cells and MMTV-neu mice. BMC Cancer (2007) 0.80

Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly. Cell Cycle (2010) 0.80

Association of serum levels of polychlorinated biphenyls with IL-8 mRNA expression in blood samples from asthmatic and non-asthmatic Japanese children. Chemosphere (2012) 0.80

Management of home blood pressure by amlodipine combined with angiotensin II receptor blocker in type 2 diabetes. Circ J (2012) 0.80

Dioxin-induced up-regulation of the active form of vitamin D is the main cause for its inhibitory action on osteoblast activities, leading to developmental bone toxicity. Toxicol Appl Pharmacol (2009) 0.79

Studies on the mechanism of rapid activation of protein tyrosine phosphorylation activities, particularly c-Src kinase, by TCDD in MCF10A. J Biochem Mol Toxicol (2004) 0.79