C M Astle

Author PubWeight™ 43.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 2010 5.54
2 Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure. J Exp Med 1982 2.77
3 Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging. J Exp Med 1978 2.25
4 Number and continuous proliferative pattern of transplanted primitive immunohematopoietic stem cells. Proc Natl Acad Sci U S A 1988 2.25
5 Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations. Exp Hematol 1993 1.86
6 Effects of transplantation on the primitive immunohematopoietic stem cell. J Exp Med 1990 1.68
7 Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol 2000 1.66
8 Maximum life spans in mice are extended by wild strain alleles. Exp Biol Med (Maywood) 2001 1.64
9 Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term. Exp Hematol 1997 1.62
10 Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. J Immunol 1989 1.57
11 Effects of food restriction on aging: separation of food intake and adiposity. Proc Natl Acad Sci U S A 1984 1.31
12 Long-term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation. Exp Hematol 1995 1.24
13 Cell lines from old immunodeficient donors give normal responses in young recipients. J Immunol 1977 1.22
14 Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid precursors defined by competitive limiting dilution analysis in vivo. J Immunol 1996 1.13
15 Development and aging of primitive hematopoietic stem cells in BALB/cBy mice. Exp Hematol 1999 1.12
16 Genetic regulation of hematopoietic stem cell exhaustion during development and growth. Exp Hematol 2005 1.09
17 Lymphoid and erythroid repopulation in B6 W-anemic mice: a new unirradiated recipient. Exp Hematol 1991 1.05
18 Delayed immune aging in diet-restricted B6CBAT6 F1 mice is associated with preservation of naive T cells. J Gerontol A Biol Sci Med Sci 1998 0.93
19 Population of lymphoid tissues in cured W-anemic mice by donor cells. Transplantation 1976 0.91
20 Primitive hematopoietic stem cell function in vivo is uniquely high in the CXB-12 mouse strain. Blood 2000 0.90
21 Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood. Blood 1997 0.90
22 Hematopoietic precursor cell exhaustion is a cause of proliferative defect in primitive hematopoietic stem cells (PHSC) after chemotherapy. Exp Hematol 1997 0.89
23 Processing by the thymus is not required for cells that cure and populate W/WV recipients. Blood 1979 0.86
24 Ultimate erythropoietic repopulating abilities of fetal, young adult, and old adult cells compared using repeated irradiation. J Exp Med 1984 0.84
25 Assessing permanent damage to primitive hematopoietic stem cells after chemotherapy using the competitive repopulation assay. Cancer Chemother Pharmacol 1993 0.83
26 Effects of marrow donor and recipient age on immune responses. J Immunol 1984 0.81
27 Hematopoietic stem cell functional failure in interleukin-2-deficient mice. J Hematother Stem Cell Res 2002 0.80
28 Splenic primitive hematopoietic stem cell (PHSC) activity is enhanced by steel factor because of PHSC proliferation. Blood 1994 0.80
29 The decrease in long-term marrow repopulating capacity seen after transplantation is not the result of irradiation-induced stromal injury. Exp Hematol 1988 0.78
30 Analysis of the stem cell sparing properties of cyclophosphamide. Eur J Haematol 2001 0.78
31 The effect of hypophysectomy on thymic aging in mice. J Immunol 1982 0.78
32 Stem cell factor improves the repopulating ability of primitive hematopoietic stem cells after sublethal irradiation (and, to a lesser extent) after bone marrow transplantation in mice. Stem Cells 1998 0.76
33 Mitogen Synergism in low-responding CBA/CaJ mice. Cell Immunol 1976 0.75
34 Effects of transplantation and age on immunohemopoietic cell growth in the splenic microenvironment. Exp Hematol 1988 0.75