1
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Hypothalamic regulation of sleep and circadian rhythms.
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Nature
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2005
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8.23
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2
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Sleep state switching.
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Neuron
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2010
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4.94
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3
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Afferents to the orexin neurons of the rat brain.
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J Comp Neurol
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2006
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2.57
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4
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Behavioral state instability in orexin knock-out mice.
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J Neurosci
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2004
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2.56
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5
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Common scale-invariant patterns of sleep-wake transitions across mammalian species.
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Proc Natl Acad Sci U S A
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2004
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2.19
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6
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Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms.
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J Neurosci
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2003
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2.15
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7
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Afferents to the ventrolateral preoptic nucleus.
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J Neurosci
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2002
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1.86
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8
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Homeostatic, circadian, and emotional regulation of sleep.
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J Comp Neurol
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2005
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1.80
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9
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Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep.
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Proc Natl Acad Sci U S A
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2005
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1.77
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10
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Elevated body temperature during sleep in orexin knockout mice.
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Am J Physiol Regul Integr Comp Physiol
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2006
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1.71
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11
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Loss of hypocretin (orexin) neurons with traumatic brain injury.
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Ann Neurol
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2009
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1.54
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12
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Neural circuitry engaged by prostaglandins during the sickness syndrome.
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Nat Neurosci
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2012
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1.35
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13
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The frustrating and mostly fruitless search for an autoimmune cause of narcolepsy.
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Sleep
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2006
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1.34
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14
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Running promotes wakefulness and increases cataplexy in orexin knockout mice.
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Sleep
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2007
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1.26
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15
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Mathematical model of network dynamics governing mouse sleep-wake behavior.
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J Neurophysiol
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2007
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1.21
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16
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Sleep neurobiology for the clinician.
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Sleep
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2004
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1.20
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17
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Sleep neurobiology from a clinical perspective.
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Sleep
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2011
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1.14
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18
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Abnormal sleep/wake dynamics in orexin knockout mice.
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Sleep
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2010
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1.10
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19
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Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice.
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Proc Natl Acad Sci U S A
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2011
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1.09
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20
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Amygdala lesions reduce cataplexy in orexin knock-out mice.
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J Neurosci
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2013
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1.09
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21
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Narcolepsy: neural mechanisms of sleepiness and cataplexy.
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J Neurosci
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2012
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1.07
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22
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Increase of histaminergic tuberomammillary neurons in narcolepsy.
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Ann Neurol
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2013
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1.04
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23
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Wake-related activity of tuberomammillary neurons in rats.
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Brain Res
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2003
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1.02
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24
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Hcrtr1 and 2 signaling differentially regulates depression-like behaviors.
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Behav Brain Res
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2011
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1.01
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25
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Orexin, drugs and motivated behaviors.
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Nat Neurosci
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2005
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0.96
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26
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Role of the medial prefrontal cortex in cataplexy.
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J Neurosci
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2013
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0.93
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27
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Narcolepsy as an adverse event following immunization: case definition and guidelines for data collection, analysis and presentation.
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Vaccine
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2012
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0.93
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28
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Control of arousal by the orexin neurons.
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Curr Opin Neurobiol
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2013
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0.92
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29
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Modafinil: a drug in search of a mechanism.
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Sleep
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2004
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0.89
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30
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The trouble with Tribbles: do antibodies against TRIB2 cause narcolepsy?
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Sleep
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2010
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0.88
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31
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Mistaken diagnosis of psychogenic gait disorder in a man with status cataplecticus ("limp man syndrome").
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Mov Disord
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2004
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0.88
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32
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Diurnal variation in CSF orexin-A in healthy male subjects.
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Sleep
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2006
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0.88
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33
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Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal.
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J Neurosci
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2014
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0.87
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34
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Orexin neurons are necessary for the circadian control of REM sleep.
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Sleep
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2009
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0.87
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35
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Narcolepsy.
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N Engl J Med
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2015
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0.86
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Orexins: looking forward to sleep, back at addiction.
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Nat Med
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2007
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0.85
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37
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Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy.
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Curr Opin Neurol
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2002
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0.84
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38
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Emerging therapeutics in sleep.
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Ann Neurol
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2013
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0.84
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39
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Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice.
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Sleep
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2013
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0.84
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40
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Do enteric neurons make hypocretin?
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Regul Pept
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2007
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0.83
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41
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Pharmacotherapy for cataplexy.
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Sleep Med Rev
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2004
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0.83
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42
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Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury.
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Ann Neurol
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2014
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0.82
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43
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Inter-hemispheric oscillations in human sleep.
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PLoS One
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2012
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0.79
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44
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Parkinson's disease, sleepiness and hypocretin/orexin.
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Brain
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2007
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0.79
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45
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Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling.
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Novartis Found Symp
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2003
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0.78
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46
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Narcolepsy caused by acute disseminated encephalomyelitis.
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Arch Neurol
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2004
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0.77
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47
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Orexin/Hypocretin: wired for wakefulness.
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Curr Biol
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2003
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0.75
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