Published in Diabetes on February 01, 2005
Insulin as an autoantigen in NOD/human diabetes. Curr Opin Immunol (2008) 1.95
Naturally acquired tolerance and sensitization to minor histocompatibility antigens in healthy family members. Blood (2009) 1.94
Subsets, expansion and activation of myeloid-derived suppressor cells. Med Microbiol Immunol (2010) 1.67
Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity. J Clin Invest (2007) 1.44
Immunological applications of stem cells in type 1 diabetes. Endocr Rev (2011) 1.20
Cells of the synovium in rheumatoid arthritis. Dendritic cells. Arthritis Res Ther (2007) 1.16
An update on the use of NOD mice to study autoimmune (Type 1) diabetes. Expert Rev Clin Immunol (2010) 1.13
Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1. J Immunol (2010) 1.04
Tracking the migration of dendritic cells by in vivo optical imaging. Neoplasia (2007) 1.00
Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same? Clin Dev Immunol (2011) 0.92
Dexamethasone/1alpha-25-dihydroxyvitamin D3-treated dendritic cells suppress colitis in the SCID T-cell transfer model. Immunology (2008) 0.90
NK depletion results in increased CCL22 secretion and Treg levels in Lewis lung carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells. Int J Cancer (2010) 0.85
The immunotherapeutic potential of dendritic cells in type 1 diabetes. Clin Exp Immunol (2010) 0.84
Tolerogenic dendritic cells pulsed with enterobacterial extract suppress development of colitis in the severe combined immunodeficiency transfer model. Immunology (2007) 0.83
The role of Gr1+ cells after anti-CD20 treatment in type 1 diabetes in nonobese diabetic mice. J Immunol (2011) 0.81
Proinsulin is encoded by an RNA splice variant in human blood myeloid cells. Proc Natl Acad Sci U S A (2006) 0.81
A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice. Clin Immunol (2015) 0.79
Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen. Mol Ther (2009) 0.79
G-CSF and Exenatide Might Be Associated with Increased Long-Term Survival of Allogeneic Pancreatic Islet Grafts. PLoS One (2016) 0.75
Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes (2010) 2.35
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. J Clin Invest (2006) 1.88
Antigen-induced regulatory T cells in autoimmunity. Nat Rev Immunol (2003) 1.87
A sensitive method for detecting proliferation of rare autoantigen-specific human T cells. J Immunol Methods (2003) 1.59
A clinical screening tool identifies autoimmune diabetes in adults. Diabetes Care (2006) 1.59
The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes. Diabetes Care (2008) 1.59
Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas. Diabetes (2005) 1.57
The insulin A-chain epitope recognized by human T cells is posttranslationally modified. J Exp Med (2005) 1.55
Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol (2011) 1.54
Guidelines for intervention trials in subjects with newly diagnosed type 1 diabetes. Diabetes (2003) 1.44
Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide. J Clin Invest (2003) 1.32
T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis. J Am Soc Nephrol (2008) 1.20
The accelerator hypothesis and increasing incidence of type 1 diabetes. Curr Opin Endocrinol Diabetes Obes (2008) 1.16
Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development. Int Immunol (2005) 1.15
Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J Clin Invest (2003) 1.14
Advanced glycation end products are direct modulators of β-cell function. Diabetes (2011) 1.14
Evidence that nasal insulin induces immune tolerance to insulin in adults with autoimmune diabetes. Diabetes (2011) 1.13
Proinsulin-a pathogenic autoantigen in type 1 diabetes. Autoimmun Rev (2003) 1.13
Distinct distribution of laminin and its integrin receptors in the pancreas. J Histochem Cytochem (2002) 1.11
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10. Nat Immunol (2013) 1.11
Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice. J Immunol (2008) 1.11
A randomized controlled trial of high-dose vitamin D2 followed by intranasal insulin in Alzheimer's disease. J Alzheimers Dis (2011) 1.10
Increased generation of dendritic cells from myeloid progenitors in autoimmune-prone nonobese diabetic mice. J Immunol (2002) 1.07
Pre-type 1 diabetes dysmetabolism: maximal sensitivity achieved with both oral and intravenous glucose tolerance testing. J Pediatr (2007) 1.06
TCR gamma delta intraepithelial lymphocytes are required for self-tolerance. J Immunol (2006) 1.06
Weight gain in early life predicts risk of islet autoimmunity in children with a first-degree relative with type 1 diabetes. Diabetes Care (2008) 1.05
An efficient method for cloning human autoantigen-specific T cells. J Immunol Methods (2005) 1.04
Understanding autoimmune diabetes: insights from mouse models. Trends Mol Med (2002) 1.04
Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells. Blood (2013) 1.01
Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells. J Cell Sci (2002) 0.99
acDCs enhance human antigen-specific T-cell responses. Blood (2011) 0.98
The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells. J Immunol (2010) 0.98
Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens. J Immunol (2010) 0.97
Trials in type 1 diabetes: Antigen-specific therapies. Clin Immunol (2013) 0.95
CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis. J Immunol (2006) 0.93
TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death. Int Immunol (2004) 0.93
Generation and expansion of regulatory human CD4(+) T-cell clones specific for pancreatic islet autoantigens. J Autoimmun (2010) 0.92
Reappraising the stereotypes of diabetes in the modern diabetogenic environment. Nat Rev Endocrinol (2009) 0.91
Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes. J Immunol (2006) 0.91
Progenitor cells in the adult pancreas. Diabetes Metab Res Rev (2004) 0.91
Human T-cells recognise N-terminally Fmoc-modified peptide. Vaccine (2003) 0.91
Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells. J Immunol (2007) 0.90
Transient blockade of CD40 ligand dissociates pathogenic from protective mucosal immunity. J Clin Invest (2002) 0.90
Growth of rotaviruses in primary pancreatic cells. J Virol (2002) 0.88
Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice. J Biol Chem (2012) 0.88
Definition of high-risk type 1 diabetes HLA-DR and HLA-DQ types using only three single nucleotide polymorphisms. Diabetes (2013) 0.87
Convergence of bone morphogenetic protein and laminin-1 signaling pathways promotes proliferation and colony formation by fetal mouse pancreatic cells. Exp Cell Res (2005) 0.87
Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis. Immunology (2009) 0.86
Revisiting regulatory T cells in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes (2012) 0.86
Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model. Xenotransplantation (2013) 0.84
Harp (harmonin-interacting, ankyrin repeat-containing protein), a novel protein that interacts with harmonin in epithelial tissues. Genes Cells (2004) 0.84
Persistence of recipient lymphocytes in NOD mice after irradiation and bone marrow transplantation. J Autoimmun (2004) 0.83
Development of autoantibodies to islet antigens during childhood: implications for preclinical type 1 diabetes screening. Pediatr Diabetes (2002) 0.83
The origin of thymic CD4+CD25+ regulatory T cells and their co-stimulatory requirements are determined after elimination of recirculating peripheral CD4+ cells. Int Immunol (2007) 0.82
CD4+ T cell proliferation in response to GAD and proinsulin in healthy, pre-diabetic, and diabetic donors. Ann N Y Acad Sci (2004) 0.82
Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas. J Autoimmun (2004) 0.82
Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid. Stem Cell Res (2007) 0.82
Mucosal tolerance to prevent type 1 diabetes: can the outcome be improved in humans? Rev Diabet Stud (2004) 0.81
Proinsulin is encoded by an RNA splice variant in human blood myeloid cells. Proc Natl Acad Sci U S A (2006) 0.81
Anti-CD45RB antibody deters xenograft rejection by modulating T cell priming and homing. Int Immunol (2002) 0.81
Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes. BMC Pediatr (2013) 0.80
Forward light scatter is a simple measure of T-cell activation and proliferation but is not universally suited for doublet discrimination. Cytometry A (2011) 0.80
Pancreatic expression and mitochondrial localization of the progestin-adipoQ receptor PAQR10. Mol Med (2008) 0.80
Dominance of cytokine- over FasL-induced impairment of the mitochondrial transmembrane potential (Deltapsim) in the pancreatic beta-cell line NIT-1. Diab Vasc Dis Res (2008) 0.80
Extracellular signals and pancreatic beta-cell development: a brief review. Mol Med (2002) 0.79
Adult pancreas side population cells expand after β cell injury and are a source of insulin-secreting cells. PLoS One (2012) 0.79
Homeostatic proliferation of intestinal intraepithelial lymphocytes precedes their migration to extra-intestinal sites. Eur J Immunol (2007) 0.79
Emerging evidence that molecules expressed by mammalian tissue grafts are recognized by the innate immune system. J Leukoc Biol (2002) 0.78
Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation. Differentiation (2005) 0.78
The Parahox gene Pdx1 is required to maintain positional identity in the adult foregut. Int J Dev Biol (2013) 0.77
An antibody-based leukocyte-capture microarray for the diagnosis of systemic lupus erythematosus. PLoS One (2013) 0.77
The non-immune RIP-Kb mouse is a useful host for islet transplantation, as the diabetes is spontaneous, mild and predictable. Int J Exp Diabetes Res (2002) 0.76
Evidence from twins for acquired cellular immune hyperactivity in type 1 diabetes. Immunology (2002) 0.76
Persistently autoantibody-negative type 1 diabetes: rich pickings or much ado about nothing? Pediatr Diabetes (2011) 0.75
Seasonal changes in preprandial glucose, A1C, and blood pressure in diabetic patients: response to Liang. Diabetes Care (2007) 0.75
Does insulin resistance need resistin? J Clin Endocrinol Metab (2007) 0.75
Late-onset autoimmune diabetes in relatives of people with type 1 diabetes. Ann N Y Acad Sci (2003) 0.75
Difference in generating mouse pancreatic epithelial cell colonies in vitro. Pancreas (2003) 0.75
Atorvastatin enhances humoral immune responses but does not alter renal injury in experimental crescentic glomerulonephritis. Nephrology (Carlton) (2009) 0.75
Pulmonary CD4+ cytokine responses in mice reveal differences in the relative immunogenicity of cold-adapted influenza A vaccine donor strains. Vaccine (2005) 0.75
Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes. Nat Immunol (2017) 0.75
Characterization of the Human Pancreas Side Population as a Potential Reservoir of Adult Stem Cells. Pancreas (2018) 0.75
High avidity antibodies to fetal pig pancreas endocrine cells transfer rejection but are not normally generated to fetal pig pancreas xenografts. Xenotransplantation (2002) 0.75
Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes. Nat Immunol (2017) 0.75