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Science
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The placenta is a niche for hematopoietic stem cells.
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Dev Cell
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2005
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The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation.
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Cell Stem Cell
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2008
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The hematopoietic stem cell and its niche: a comparative view.
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Genes Dev
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2007
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Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells.
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2009
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Dev Cell
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2005
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10
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Lymphoid priming in human bone marrow begins before expression of CD10 with upregulation of L-selectin.
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Nat Immunol
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The first trimester human placenta is a site for terminal maturation of primitive erythroid cells.
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Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells.
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PLoS Genet
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Targeting leukemia stem cells.
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Nat Biotechnol
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Expansion on stromal cells preserves the undifferentiated state of human hematopoietic stem cells despite compromised reconstitution ability.
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Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo.
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Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.
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Placenta as a newly identified source of hematopoietic stem cells.
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Curr Opin Hematol
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2010
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DNA methylation is a guardian of stem cell self-renewal and multipotency.
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Sex hormone drives blood stem cell reproduction.
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