|
1
|
HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.
|
Stem Cells
|
2006
|
1.66
|
|
2
|
C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment.
|
Blood
|
2007
|
1.52
|
|
3
|
Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPalpha expression.
|
Blood
|
2003
|
1.47
|
|
4
|
The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.
|
Mol Cell Biol
|
2003
|
1.38
|
|
5
|
C/EBPalpha directs monocytic commitment of primary myeloid progenitors.
|
Blood
|
2006
|
1.31
|
|
6
|
AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression.
|
J Biol Chem
|
2004
|
1.31
|
|
7
|
Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis.
|
Blood
|
2012
|
1.22
|
|
8
|
Cell cycle inhibition mediated by the outer surface of the C/EBPalpha basic region is required but not sufficient for granulopoiesis.
|
Oncogene
|
2003
|
1.15
|
|
9
|
Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression.
|
Blood
|
2011
|
1.13
|
|
10
|
CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor.
|
Blood
|
2002
|
1.12
|
|
11
|
RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53.
|
Oncogene
|
2004
|
1.12
|
|
12
|
M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.
|
Blood
|
2009
|
1.11
|
|
13
|
Twist-2 controls myeloid lineage development and function.
|
PLoS Biol
|
2008
|
1.10
|
|
14
|
CCAAT/enhancer binding protein alpha (C/EBPalpha) and C/EBPalpha myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-kappaB p50.
|
Mol Cancer Res
|
2005
|
1.10
|
|
15
|
AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription.
|
J Leukoc Biol
|
2011
|
1.10
|
|
16
|
Cross-talk between regulators of myeloid development: C/EBPalpha binds and activates the promoter of the PU.1 gene.
|
J Leukoc Biol
|
2003
|
1.09
|
|
17
|
TEL-AML1, expressed from t(12;21) in human acute lymphocytic leukemia, induces acute leukemia in mice.
|
Cancer Res
|
2002
|
1.06
|
|
18
|
C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation.
|
Blood
|
2006
|
1.06
|
|
19
|
Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.
|
J Biol Chem
|
2002
|
1.05
|
|
20
|
Induction of granulocytic differentiation by 2 pathways.
|
Blood
|
2002
|
1.03
|
|
21
|
NF-kappa B p50 regulates C/EBP alpha expression and inflammatory cytokine-induced neutrophil production.
|
J Immunol
|
2009
|
1.00
|
|
22
|
Targeted inhibition of FLT3 overcomes the block to myeloid differentiation in 32Dcl3 cells caused by expression of FLT3/ITD mutations.
|
Blood
|
2002
|
1.00
|
|
23
|
Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation.
|
Blood
|
2007
|
0.99
|
|
24
|
The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation.
|
J Biol Chem
|
2004
|
0.96
|
|
25
|
Multimerization via its myosin domain facilitates nuclear localization and inhibition of core binding factor (CBF) activities by the CBFbeta-smooth muscle myosin heavy chain myeloid leukemia oncoprotein.
|
Mol Cell Biol
|
2002
|
0.96
|
|
26
|
AML1 stimulates G1 to S progression via its transactivation domain.
|
Oncogene
|
2002
|
0.95
|
|
27
|
C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes.
|
Blood
|
2011
|
0.92
|
|
28
|
Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3.
|
J Biol Chem
|
2010
|
0.92
|
|
29
|
SHP2 tyrosine phosphatase stimulates CEBPA gene expression to mediate cytokine-dependent granulopoiesis.
|
Blood
|
2011
|
0.91
|
|
30
|
Acceleration of G(1) cooperates with core binding factor beta-smooth muscle myosin heavy chain to induce acute leukemia in mice.
|
Cancer Res
|
2002
|
0.88
|
|
31
|
Cyclin E is a target of WT1 transcriptional repression.
|
J Biol Chem
|
2002
|
0.86
|
|
32
|
CCAAT/enhancer binding protein epsilon: changes in function upon phosphorylation by p38 MAP kinase.
|
Blood
|
2005
|
0.85
|
|
33
|
C/EBPalphap30, a myeloid leukemia oncoprotein, limits G-CSF receptor expression but not terminal granulopoiesis via site-selective inhibition of C/EBP DNA binding.
|
Oncogene
|
2004
|
0.85
|
|
34
|
C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction.
|
Mol Cancer Res
|
2011
|
0.85
|
|
35
|
Reciprocal effects of C/EBPalpha and PKCdelta on JunB expression and monocytic differentiation depend upon the C/EBPalpha basic region.
|
Blood
|
2003
|
0.84
|
|
36
|
c-Myc overcomes cell cycle inhibition by CBFbeta-SMMHC, a myeloid leukemia oncoprotein.
|
Cancer Biol Ther
|
2002
|
0.83
|
|
37
|
Erythroid maturation and proliferation arrest: the GATA-1 connection: comment on: Papetti M. Cell cycle 2010; 9:1972-80.
|
Cell Cycle
|
2010
|
0.76
|
|
38
|
Epstein-Barr virus-associated central nervous system lymphoproliferative disease in a patient with acquired immunodeficiency syndrome responsive to highly active antiretroviral therapy.
|
Clin Infect Dis
|
2008
|
0.75
|