Published in Am J Respir Cell Mol Biol on January 27, 2005
Potential therapeutic role for statins in respiratory disease. Thorax (2006) 1.49
Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. Am J Respir Crit Care Med (2009) 1.38
Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo. J Cell Commun Signal (2009) 1.33
Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis (2008) 1.11
Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis. J Biol Chem (2011) 0.99
Emerging roles for cholesterol and lipoproteins in lung disease. Pulm Pharmacol Ther (2012) 0.97
Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription. Am J Physiol Cell Physiol (2014) 0.92
Immunosuppression in lung transplantation. J Thorac Dis (2014) 0.92
Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J (2013) 0.91
RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis. Respir Res (2006) 0.90
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. Respir Res (2011) 0.89
Innovative approaches to the therapy of fibrosis. Curr Opin Rheumatol (2009) 0.88
Simvastatin modulates cellular components in influenza A virus-infected cells. Int J Mol Med (2014) 0.80
Simvastatin attenuates intestinal fibrosis independent of the anti-inflammatory effect by promoting fibroblast/myofibroblast apoptosis in the regeneration/healing process from TNBS-induced colitis. Dig Dis Sci (2011) 0.80
Mechanisms of action and efficacy of statins against influenza. Biomed Res Int (2014) 0.78
Simvastatin Reduces Capsular Fibrosis around Silicone Implants. J Korean Med Sci (2016) 0.77
Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis. Thorax (2016) 0.75
Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung-targeted approach to deliver statins. Physiol Rep (2015) 0.75
Impact of Statins on Gene Expression in Human Lung Tissues. PLoS One (2015) 0.75
Global gene profiling of aging lungs in Atp8b1 mutant mice. Aging (Albany NY) (2016) 0.75
Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study. J Cell Mol Med (2015) 0.75
Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates. J Allergy Clin Immunol (2002) 2.03
PduA is a shell protein of polyhedral organelles involved in coenzyme B(12)-dependent degradation of 1,2-propanediol in Salmonella enterica serovar typhimurium LT2. J Bacteriol (2002) 1.93
Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2002) 1.76
Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin. Am J Pathol (2003) 1.64
Preparing the wound bed 2003: focus on infection and inflammation. Ostomy Wound Manage (2003) 1.63
Growth factors in idiopathic pulmonary fibrosis: relative roles. Respir Res (2001) 1.55
Ratios of activated matrix metalloproteinase-9 to tissue inhibitor of matrix metalloproteinase-1 in wound fluids are inversely correlated with healing of pressure ulcers. Wound Repair Regen (2002) 1.51
Connective tissue growth factor expression and action in human corneal fibroblast cultures and rat corneas after photorefractive keratectomy. Invest Ophthalmol Vis Sci (2003) 1.31
Impact of engineered surface microtopography on biofilm formation of Staphylococcus aureus. Biointerphases (2007) 1.28
Optical coherence tomography: real-time imaging of bronchial airways microstructure and detection of inflammatory/neoplastic morphologic changes. Clin Cancer Res (2006) 1.27
Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress. Invest Ophthalmol Vis Sci (2004) 1.26
Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro. Invest Ophthalmol Vis Sci (2003) 1.20
PduL is an evolutionarily distinct phosphotransacylase involved in B12-dependent 1,2-propanediol degradation by Salmonella enterica serovar typhimurium LT2. J Bacteriol (2006) 1.17
TGF-beta- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling. Am J Physiol Heart Circ Physiol (2007) 1.16
Expression of connective tissue growth factor after glaucoma filtration surgery in a rabbit model. Invest Ophthalmol Vis Sci (2004) 1.12
Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring. Am J Pathol (2003) 1.11
Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism. Am J Physiol Lung Cell Mol Physiol (2004) 1.08
The pro-inflammatory environment in recalcitrant diabetic foot wounds. Int Wound J (2008) 1.08
Immunohistochemical localization of EGF, TGF-alpha, TGF-beta, and their receptors in rat corneas during healing of excimer laser ablation. Curr Eye Res (2006) 1.07
Gene transfer into rabbit keratocytes using AAV and lipid-mediated plasmid DNA vectors with a lamellar flap for stromal access. Exp Eye Res (2003) 1.07
Human rhinovirus selectively modulates membranous and soluble forms of its intercellular adhesion molecule-1 (ICAM-1) receptor to promote epithelial cell infectivity. J Biol Chem (2003) 1.04
Use of optical coherence tomography in delineating airways microstructure: comparison of OCT images to histopathological sections. Phys Med Biol (2004) 0.98
Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms. Respir Res (2013) 0.98
Early differential MMP-2 and -9 dynamics during flow-induced arterial and vein graft adaptations. J Surg Res (2006) 0.97
TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling. Exp Cell Res (2007) 0.96
Temporal patterns of gene expression in murine cutaneous burn wound healing. Physiol Genomics (2004) 0.95
Idiopathic pulmonary fibrosis: immunohistochemical analysis provides fresh insights into lung tissue remodelling with implications for novel prognostic markers. Int J Clin Exp Pathol (2012) 0.95
Differential expression and activity of matrix metalloproteinases during flow-modulated vein graft remodeling. J Vasc Surg (2004) 0.95
CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J (2012) 0.94
Topical advances in wound care. Gynecol Oncol (2008) 0.93
A connective tissue growth factor signaling receptor in corneal fibroblasts. Invest Ophthalmol Vis Sci (2012) 0.92
Development of a microarray chip for gene expression in rabbit ocular research. Mol Vis (2007) 0.92
Microarray analysis of gene expression patterns during healing of rat corneas after excimer laser photorefractive keratectomy. Invest Ophthalmol Vis Sci (2002) 0.92
Growth factor, cytokine and protease interactions during corneal wound healing. Ocul Surf (2003) 0.91
Microarray analysis of the failure of filtering blebs in a rat model of glaucoma filtering surgery. Invest Ophthalmol Vis Sci (2004) 0.90
Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo. PLoS One (2011) 0.90
Detection of connective tissue growth factor (CTGF) in human tear fluid: preliminary results. Acta Ophthalmol Scand (2003) 0.90
Hammerhead ribozyme targeting connective tissue growth factor mRNA blocks transforming growth factor-beta mediated cell proliferation. Exp Eye Res (2004) 0.89
MicroRNA signature in wound healing following excimer laser ablation: role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 expression levels in rabbit corneal fibroblasts. Invest Ophthalmol Vis Sci (2013) 0.88
Role of connective tissue growth factor in breast implant elastomer capsular formation. Ann Plast Surg (2003) 0.88
Vorinostat: a potent agent to prevent and treat laser-induced corneal haze. J Refract Surg (2012) 0.88
Glucose toxic effects on granulation tissue productive cells: the diabetics' impaired healing. Biomed Res Int (2012) 0.87
Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice. Hepatology (2015) 0.86
Development of a novel ex vivo porcine skin explant model for the assessment of mature bacterial biofilms. Wound Repair Regen (2013) 0.86
Proteolytic processing of connective tissue growth factor in normal ocular tissues and during corneal wound healing. Invest Ophthalmol Vis Sci (2012) 0.86
Science and strategy for preventing and managing corneal ulceration. Ocul Surf (2007) 0.85
Conditional knockout of CTGF affects corneal wound healing. Invest Ophthalmol Vis Sci (2014) 0.85
Club cells inhibit alveolar epithelial wound repair via TRAIL-dependent apoptosis. Eur Respir J (2012) 0.85
The effect of topical tripeptide-copper complex on healing of ischemic open wounds. Vet Surg (2003) 0.85
Time course of lesion development in the hairless guinea-pig model of sulfur mustard-induced dermal injury. Wound Repair Regen (2011) 0.85
Detection of connective tissue growth factor in human aqueous humor. Ophthalmic Res (2002) 0.85
Effect of Vacuum-Assisted Closure Therapy on the expression of cytokines and proteases in wound fluid of adults with pressure ulcers. Wound Repair Regen (2006) 0.84
Wound dressing components degrade proteins detrimental to wound healing. Int Wound J (2008) 0.84
Analysis of gene expression patterns in human postburn hypertrophic scars. J Burn Care Rehabil (2003) 0.84
Biofilm formation by Pseudomonas aeruginosa on ossicular reconstruction prostheses. Am J Otolaryngol (2009) 0.84
Ectopic epithelial implants following surface ablation of the cornea. Invest Ophthalmol Vis Sci (2012) 0.83
Prevention of ocular scarring post glaucoma filtration surgery using the inflammatory cell and platelet binding modulator saratin in a rabbit model. PLoS One (2012) 0.83
Tympanic membrane metalloproteinase inflammatory response. Otolaryngol Head Neck Surg (2003) 0.82
Safety and efficacy of carbomethylcellulose foam in guinea pig middle ear surgery. Otolaryngol Head Neck Surg (2010) 0.82
Effect of connective tissue growth factor on protein kinase expression and activity in human corneal fibroblasts. Invest Ophthalmol Vis Sci (2012) 0.82
Hammerhead ribozyme-mediated knockdown of mRNA for fibrotic growth factors: transforming growth factor-beta 1 and connective tissue growth factor. Methods Mol Biol (2012) 0.81
Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA. J Virol (2008) 0.81
Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model. J Glaucoma (2013) 0.81
Alpha 1-antitrypsin and ilomastat inhibit inflammatory proteases present in human middle ear effusions. Laryngoscope (2003) 0.80
IFN-gamma regulation of ICAM-1 receptors in bronchial epithelial cells: soluble ICAM-1 release inhibits human rhinovirus infection. J Inflamm (Lond) (2008) 0.79
Matrix metalloproteinases in a gerbil cholesteatoma model. Otolaryngol Head Neck Surg (2003) 0.79
TIME heals all wounds. Nursing (2004) 0.79
Alteration of Smad3 signaling in ischemic rabbit dermal ulcer wounds. Wound Repair Regen (2007) 0.78
Evaluation of various compounds to inhibit activity of matrix metalloproteinases in the tear film of horses with ulcerative keratitis. Am J Vet Res (2003) 0.78
A corneal scarring model. Methods Mol Biol (2013) 0.78
The effect of negative pressure wound therapy with periodic instillation using antimicrobial solutions on Pseudomonas aeruginosa biofilm on porcine skin explants. Int Wound J (2013) 0.78
The progression of haze formation in rabbit corneas following phototherapeutic keratectomy. Invest Ophthalmol Vis Sci (2013) 0.78
Comparison of single versus multiple injections of the protein saratin for prolonging bleb survival in a rabbit model. Invest Ophthalmol Vis Sci (2012) 0.78
Effect of ossicular prosthesis biofilms on middle ear scarring and hearing outcomes. Otol Neurotol (2009) 0.77
Methods in reepithelialization. A porcine model of partial-thickness wounds. Methods Mol Med (2003) 0.77
Microbial barriers. Clin Plast Surg (2012) 0.76
Arginine metabolites in wound fluids from pressure ulcers: a pilot study. Biol Res Nurs (2008) 0.76
AM-111 prevents hearing loss from semicircular canal injury in otitis media. Laryngoscope (2010) 0.76
BMP2 repression and optimized culture conditions promote human bone marrow-derived mesenchymal stem cell isolation. Regen Med (2015) 0.76
Republication of color figures. Arch Ophthalmol (2002) 0.75
Inhibition of matrix metalloproteinases in gerbil cholesteatoma: preliminary findings. Otolaryngol Head Neck Surg (2002) 0.75
Combat Wound Initiative program. Mil Med (2010) 0.75
Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study. Otol Neurotol (2010) 0.75
Biofilm formation on silicone tympanostomy tubes with polyvinylpyrrolidone coating. Arch Otolaryngol Head Neck Surg (2011) 0.75
Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla. Laryngoscope (2003) 0.75
Alpha1-antitrypsin single dose adjuvant therapy for acute otitis media. Otolaryngol Head Neck Surg (2006) 0.75
Inflammatory proteases in chronic otitis externa. Laryngoscope (2005) 0.75