Published in Diabetes Care on February 01, 2005
Understanding type 1 diabetes through genetics: advances and prospects. Nat Rev Genet (2011) 1.64
Genetics of type 1 diabetes. Clin Chem (2011) 1.37
Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals. Ann N Y Acad Sci (2013) 1.02
The interplay of autoimmunity and insulin resistance in type 1 diabetes. Discov Med (2012) 0.96
Challenges in diagnosing type 1 diabetes in different populations. Diabetes Metab J (2012) 0.91
The next big idea. Diabetes Technol Ther (2013) 0.75
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 14.33
Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. N Engl J Med (2009) 6.89
Risk of pediatric celiac disease according to HLA haplotype and country. N Engl J Med (2014) 5.44
Autoimmune polyendocrine syndromes. N Engl J Med (2004) 5.11
Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet (2011) 4.30
Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA (2005) 3.61
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial. Lancet (2011) 3.13
Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data. Diabetes (2012) 3.11
A prospective study of the incidence of childhood celiac disease. J Pediatr (2003) 2.50
Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab (2004) 2.19
Testing the NKT cell hypothesis of human IDDM pathogenesis. J Clin Invest (2002) 1.98
CD4+CD25high regulatory T cells in human autoimmune diabetes. J Autoimmun (2005) 1.96
A report on the International Transglutaminase Autoantibody Workshop for Celiac Disease. Am J Gastroenterol (2009) 1.94
Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening. Diabetes (2008) 1.90
Extreme genetic risk for type 1A diabetes. Proc Natl Acad Sci U S A (2006) 1.90
Comparison of accuracy and safety of the SEVEN and the Navigator continuous glucose monitoring systems. Diabetes Technol Ther (2009) 1.88
Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young. Diabetes Care (2011) 1.86
Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex. Diabetes (2007) 1.84
Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells. J Immunol (2009) 1.83
Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes (2010) 1.67
Impact of celiac autoimmunity on children with type 1 diabetes. J Pediatr (2007) 1.64
Autoimmune polyglandular syndromes. Nat Rev Endocrinol (2010) 1.60
Altered Toll-like receptor signaling pathways in human type 1 diabetes. J Mol Med (Berl) (2010) 1.60
Hypertension prevalence, awareness, treatment, and control in an adult type 1 diabetes population and a comparable general population. Diabetes Care (2005) 1.59
Epidemiology, pathophysiology, and prognostic implications of cystic fibrosis-related diabetes: a technical review. Diabetes Care (2010) 1.57
Glycemic parameters with multiple daily injections using insulin glargine versus insulin pump. Diabetes Technol Ther (2004) 1.48
Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups. Diabetes Care (2005) 1.43
A1C between 5.7 and 6.4% as a marker for identifying pre-diabetes, insulin sensitivity and secretion, and cardiovascular risk factors: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care (2010) 1.41
Insulin resistance, beta-cell dysfunction, and conversion to type 2 diabetes in a multiethnic population: the Insulin Resistance Atherosclerosis Study. Diabetes Care (2009) 1.40
TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial. Ann N Y Acad Sci (2006) 1.40
Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes (2006) 1.38
Genetics of type 1 diabetes. Clin Chem (2011) 1.37
Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease. J Pediatr Gastroenterol Nutr (2007) 1.30
Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8. J Immunol (2011) 1.28
Time lag characterization of two continuous glucose monitoring systems. Diabetes Res Clin Pract (2010) 1.28
Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care (2010) 1.25
Association of the PTPN22/LYP gene with type 1 diabetes. Pediatr Diabetes (2006) 1.25
Additional autoimmune disease found in 33% of patients at type 1 diabetes onset. Diabetes Care (2011) 1.25
B-lymphocyte depletion with rituximab and β-cell function: two-year results. Diabetes Care (2013) 1.25
Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide. Diabetes (2002) 1.23
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. J Clin Invest (2014) 1.22
Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment. Diabetes Care (2013) 1.21
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study. Diabetologia (2015) 1.20
Endocrine and immunogenetic testing in individuals with type 1 diabetes and 21-hydroxylase autoantibodies: Addison's disease in a high-risk population. J Clin Endocrinol Metab (2004) 1.20
Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest (2015) 1.19
Cardiovascular disease mortality in Hispanics and non-Hispanic whites. Am J Epidemiol (2002) 1.17
Reduced severe hypoglycemia with insulin glargine in intensively treated adults with type 1 diabetes. Diabetes Technol Ther (2004) 1.17
Need for quantitative assessment of transglutaminase autoantibodies for celiac disease in screening-identified children. J Pediatr (2005) 1.14
Continuous home monitoring of glucose: improved glycemic control with real-life use of continuous glucose sensors in adult subjects with type 1 diabetes. Diabetes Care (2007) 1.12
Vitamin D deficiency and coronary artery calcification in subjects with type 1 diabetes. Diabetes Care (2010) 1.11
Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation. J Immunol (2011) 1.10
Dysregulated Toll-like receptor-induced interleukin-1β and interleukin-6 responses in subjects at risk for the development of type 1 diabetes. Diabetes (2012) 1.05
Clinical features of children with screening-identified evidence of celiac disease. Pediatrics (2004) 1.04
Prediabetes: prediction and prevention trials. Endocrinol Metab Clin North Am (2004) 1.03
Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes? Diabetes (2009) 1.02
Effects of non-HLA gene polymorphisms on development of islet autoimmunity and type 1 diabetes in a population with high-risk HLA-DR,DQ genotypes. Diabetes (2012) 1.01
Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist. J Pharmacol Exp Ther (2005) 1.01
Improved glycemic control in intensively treated adult subjects with type 1 diabetes using insulin guidance software. Diabetes Technol Ther (2008) 1.01
HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population. Diabetes (2007) 1.00
Improved glycemic control without an increase in severe hypoglycemic episodes in intensively treated patients with type 1 diabetes receiving morning, evening, or split dose insulin glargine. Diabetes Res Clin Pract (2004) 1.00
Plasma micronutrients are associated with dietary intake and environmental tobacco smoke exposure in a paediatric population. Public Health Nutr (2007) 0.99
Type 1 diabetes intervention trials 2007: where are we and where are we going? Curr Opin Endocrinol Diabetes Obes (2007) 0.99
Performance of HbA1c as an early diagnostic indicator of type 1 diabetes in children and youth. Diabetes Care (2012) 0.99
Inflammatory markers and diabetic retinopathy in type 1 diabetes. Diabetes Care (2005) 0.98
Ideal cardiovascular health and the prevalence and progression of coronary artery calcification in adults with and without type 1 diabetes. Diabetes Care (2013) 0.97
Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes. Cardiovasc Diabetol (2011) 0.96
The genetics of autoimmune polyendocrine syndrome type II. Endocrinol Metab Clin North Am (2002) 0.95
Rhinocerebral mucormycosis complicated by internal carotid artery thrombosis in a pediatric patient with type 1 diabetes mellitus: a case report and review of the literature. Pediatr Diabetes (2005) 0.94
Fluctuating transglutaminase autoantibodies are related to histologic features of celiac disease. Clin Gastroenterol Hepatol (2003) 0.93
Association of non-HLA genes with type 1 diabetes autoimmunity. Diabetes (2005) 0.93
Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study. Diabetes Care (2012) 0.92
Haplotype analysis discriminates genetic risk for DR3-associated endocrine autoimmunity and helps define extreme risk for Addison's disease. J Clin Endocrinol Metab (2010) 0.92
T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading. J Clin Immunol (2004) 0.91
Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes. J Clin Endocrinol Metab (2009) 0.91
Impaired fasting glucose and impaired glucose tolerance have distinct lipoprotein and apolipoprotein changes: the insulin resistance atherosclerosis study. J Clin Endocrinol Metab (2013) 0.89
Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring) (2014) 0.89
Urinary F2-isoprostanes in young healthy children at risk for type 1 diabetes mellitus. Free Radic Biol Med (2003) 0.88
Extrapancreatic autoantibody profiles in type I diabetes. PLoS One (2012) 0.88
HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes. J Immunol (2004) 0.87
Genetic prediction of autoimmunity: initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetes. J Autoimmun (2005) 0.87
Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers. Pediatr Diabetes (2013) 0.85
An enzyme linked immunosorbent assay (ELISA) for the determination of the human haptoglobin phenotype. Clin Chem Lab Med (2013) 0.85
Calcium and phosphate concentrations and future development of type 2 diabetes: the Insulin Resistance Atherosclerosis Study. Diabetologia (2014) 0.84
Prospective association between inflammatory markers and progression of coronary artery calcification in adults with and without type 1 diabetes. Diabetes Care (2013) 0.82
Dominant suppression of Addison's disease associated with HLA-B15. J Clin Endocrinol Metab (2011) 0.82
Differences in LDL oxidizability by glycemic status: the insulin resistance atherosclerosis study. Diabetes Care (2003) 0.81
Insulin lispro therapy in pregnancies complicated by type 1 diabetes: glycemic control and maternal and fetal outcomes. Endocr Pract (2003) 0.80
Predicting the onset of Addison's disease: ACTH, renin, cortisol and 21-hydroxylase autoantibodies. Clin Endocrinol (Oxf) (2012) 0.79