Giuseppe Paolisso

Author PubWeight™ 160.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
2 A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet 2008 4.75
3 Diabetes mellitus in older people: position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes. J Am Med Dir Assoc 2012 3.77
4 Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes 2008 3.76
5 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
6 Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol Endocrinol Metab 2003 2.51
7 Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition. Diabetes Care 2012 2.43
8 Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control. J Clin Endocrinol Metab 2003 2.40
9 Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations. J Diabetes Complications 2009 2.33
10 Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals. J Am Coll Cardiol 2002 2.23
11 Insulin resistance in cognitive impairment: the InCHIANTI study. Arch Neurol 2005 2.00
12 "The older, the wiser" in prostate cancer treatment choices? Ann Intern Med 2013 1.96
13 Morning blood pressure surge as a destabilizing factor of atherosclerotic plaque: role of ubiquitin-proteasome activity. Hypertension 2007 1.77
14 Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. Am J Physiol Endocrinol Metab 2002 1.76
15 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
16 Tight glycemic control reduces heart inflammation and remodeling during acute myocardial infarction in hyperglycemic patients. J Am Coll Cardiol 2009 1.67
17 Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2009 1.61
18 Use of a non-specific immunomodulation therapy as a therapeutic vasculogenesis strategy in no-option critical limb ischemia patients. Atherosclerosis 2009 1.51
19 Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech Ageing Dev 2005 1.49
20 Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome X. Mol Aspects Med 2003 1.48
21 Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus. Am J Clin Nutr 2003 1.41
22 Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome. J Lipid Res 2009 1.38
23 Brief episodes of silent atrial fibrillation predict clinical vascular brain disease in type 2 diabetic patients. J Am Coll Cardiol 2013 1.36
24 Diverse effect of inflammatory markers on insulin resistance and insulin-resistance syndrome in the elderly. J Am Geriatr Soc 2004 1.36
25 Insulin resistance and muscle strength in older persons. J Gerontol A Biol Sci Med Sci 2005 1.36
26 European Diabetes Working Party for Older People 2011 clinical guidelines for type 2 diabetes mellitus. Executive summary. Diabetes Metab 2011 1.34
27 Insulin resistance and executive dysfunction in older persons. J Am Geriatr Soc 2004 1.32
28 Relationships between daily acute glucose fluctuations and cognitive performance among aged type 2 diabetic patients. Diabetes Care 2010 1.23
29 Mediterranean diet, telomere maintenance and health status among elderly. PLoS One 2013 1.15
30 High interleukin-6 plasma levels are associated with low HDL-C levels in community-dwelling older adults: the InChianti study. Atherosclerosis 2006 1.13
31 Association between hormones and metabolic syndrome in older Italian men. J Am Geriatr Soc 2006 1.13
32 The ubiquitin-proteasome system contributes to the inflammatory injury in ischemic diabetic myocardium: the role of glycemic control. Cardiovasc Pathol 2009 1.11
33 Circulating microRNA changes in heart failure patients treated with cardiac resynchronization therapy: responders vs. non-responders. Eur J Heart Fail 2013 1.10
34 Safety of type 2 diabetes treatment with repaglinide compared with glibenclamide in elderly people: A randomized, open-label, two-period, cross-over trial. Diabetes Care 2006 1.10
35 Increased activity of the ubiquitin-proteasome system in patients with symptomatic carotid disease is associated with enhanced inflammation and may destabilize the atherosclerotic plaque: effects of rosiglitazone treatment. J Am Coll Cardiol 2006 1.09
36 Glucose regulation and oxidative stress in healthy centenarians. Exp Gerontol 2003 1.08
37 Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: a potential role for leptin in mediating human left ventricular hypertrophy. J Clin Endocrinol Metab 2005 1.07
38 Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation. BMC Cardiovasc Disord 2014 1.07
39 Glucose variability: An emerging target for the treatment of diabetes mellitus. Diabetes Res Clin Pract 2013 1.05
40 Insulin resistance is an independent risk factor for atherosclerosis in rheumatoid arthritis. Diab Vasc Dis Res 2007 1.04
41 Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity. Exp Gerontol 2004 1.03
42 Effects of nitric oxide on cell proliferation: novel insights. J Am Coll Cardiol 2013 1.03
43 Peri-procedural tight glycemic control during early percutaneous coronary intervention is associated with a lower rate of in-stent restenosis in patients with acute ST-elevation myocardial infarction. J Clin Endocrinol Metab 2012 1.00
44 Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study. Am J Physiol Endocrinol Metab 2006 1.00
45 Functional role of miRNA in cardiac resynchronization therapy. Pharmacogenomics 2014 1.00
46 Cytokine milieu tends toward inflammation in type 2 diabetes. Diabetes Care 2003 1.00
47 Pulse wave velocity is associated with muscle mass decline: Health ABC study. Age (Dordr) 2011 0.99
48 Higher circulating levels of IGF-1 are associated with longer leukocyte telomere length in healthy subjects. Mech Ageing Dev 2009 0.99
49 Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database. Nutr Metab Cardiovasc Dis 2007 0.98
50 Rosiglitazone and cognitive stability in older individuals with type 2 diabetes and mild cognitive impairment. Diabetes Care 2010 0.98
51 Mediterranean diet and mobility decline in older persons. Exp Gerontol 2010 0.95
52 Relationship between higher estradiol levels and 9-year mortality in older women: the Invecchiare in Chianti study. J Am Geriatr Soc 2009 0.95
53 Repaglinide administration improves brachial reactivity in type 2 diabetic patients. Diabetes Care 2005 0.95
54 Bariatric surgery reduces oxidative stress by blunting 24-h acute glucose fluctuations in type 2 diabetic obese patients. Diabetes Care 2009 0.95
55 Arterial stiffness and cognition in elderly persons with impaired glucose tolerance and microalbuminuria. J Gerontol A Biol Sci Med Sci 2008 0.95
56 Weight loss through gastric banding: effects on TSH and thyroid hormones in obese subjects with normal thyroid function. Obesity (Silver Spring) 2009 0.95
57 Is chronic inflammation a determinant of blood pressure in the elderly? Am J Hypertens 2003 0.94
58 FFAs and QT intervals in obese women with visceral adiposity: effects of sustained weight loss over 1 year. J Clin Endocrinol Metab 2002 0.94
59 The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes. Cardiovasc Diabetol 2007 0.94
60 Tight glycemic control may increase regenerative potential of myocardium during acute infarction. J Clin Endocrinol Metab 2011 0.93
61 Cardiac autonomic activity and Type II diabetes mellitus. Clin Sci (Lond) 2005 0.92
62 Changing the metabolic profile by large-volume liposuction: a clinical study conducted with 123 obese women. Aesthetic Plast Surg 2005 0.92
63 Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians. Eur J Hum Genet 2002 0.91
64 Dipeptidyl peptidase 4 inhibition may facilitate healing of chronic foot ulcers in patients with type 2 diabetes. Exp Diabetes Res 2012 0.91
65 Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice. Exp Gerontol 2009 0.91
66 Cytokinome profile of patients with type 2 diabetes and/or chronic hepatitis C infection. PLoS One 2012 0.91
67 Estradiol and metabolic syndrome in older italian men: The InCHIANTI Study. J Androl 2008 0.90
68 Blood pressure and cardiac autonomic nervous system in obese type 2 diabetic patients: effect of metformin administration. Am J Hypertens 2004 0.88
69 Distracted driving and crash risk. N Engl J Med 2014 0.88
70 Effects of ubiquitin-proteasome system deregulation on the vascular senescence and atherosclerosis process in elderly patients. J Gerontol A Biol Sci Med Sci 2008 0.86
71 Effects of soy isoflavones on endothelial function in healthy postmenopausal women. Menopause 2005 0.86
72 Consensus Document on substitution therapy with DHEA in the elderly. Aging Clin Exp Res 2006 0.86
73 Glucose control in the older patient: from intensive, to effective and safe. Aging Clin Exp Res 2009 0.85
74 Diabetes, ubiquitin proteasome system and atherosclerotic plaque rupture. Circ Res 2007 0.85
75 Insulin-induced changes in beta-adrenergic response: an experimental study in the isolated rat papillary muscle. Am J Hypertens 2005 0.85
76 A new pleiotropic effect of statins in elderly: modulation of telomerase activity. FASEB J 2013 0.85
77 New approaches to treating type 2 diabetes mellitus in the elderly: role of incretin therapies. Drugs Aging 2008 0.85
78 The -8 UTR C/G polymorphism of PSMA6 gene is associated with susceptibility to myocardial infarction in type 2 diabetic patients. Atherosclerosis 2008 0.85
79 Endothelial function and menopause: effects of raloxifene administration. J Clin Endocrinol Metab 2003 0.85
80 Plasma polyunsaturated fatty acids and age-related physical performance decline. Rejuvenation Res 2009 0.85
81 Effects of a 6-days-a-week low protein diet regimen on depressive symptoms in young-old type 2 diabetic patients. Nutrition 2010 0.84
82 Evidence for anti-inflammatory effects of combined administration of vitamin E and C in older persons with impaired fasting glucose: impact on insulin action. J Am Coll Nutr 2008 0.84
83 Different prevalence of metabolic control and chronic complication rate according to the time of referral to a diabetes care unit in the elderly. Acta Diabetol 2013 0.83
84 Consensus Document on substitution therapy with testosterone in hypoandrogenic elderly men. Aging Clin Exp Res 2002 0.83
85 Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: effects of short- and long-term exposure. Am J Hypertens 2002 0.83
86 The IRS2 Gly1057Asp variant is associated with human longevity. J Gerontol A Biol Sci Med Sci 2009 0.83
87 A multicentre, randomized study of telmisartan versus carvedilol for prevention of atrial fibrillation recurrence in hypertensive patients. J Renin Angiotensin Aldosterone Syst 2012 0.82
88 Diabetes care targets in older persons. Diabetes Res Clin Pract 2009 0.82
89 Metabolic journey to healthy longevity. Horm Res 2009 0.82
90 Three-dimensional echocardiographic and magnetic resonance assessment of the effect of telmisartan compared with carvedilol on left ventricular mass a multicenter, randomized, longitudinal study. Am J Hypertens 2005 0.82
91 Insulin-like growth factor-1 bioactivity plays a prosurvival role in older participants. J Gerontol A Biol Sci Med Sci 2013 0.81
92 Innate immune activity in plaque of patients with untreated and L-thyroxine-treated subclinical hypothyroidism. J Clin Endocrinol Metab 2011 0.81
93 Relationship between autonomic cardiac activity, beta-cell function, anthropometrics and metabolic indices in type II diabetics. Clin Endocrinol (Oxf) 2002 0.81
94 Altered oxido-reductive state in the diabetic heart: loss of cardioprotection due to protein disulfide isomerase. Mol Med 2011 0.81
95 Opposite role of pro-inflammatory alleles in acute myocardial infarction and longevity: results of studies performed in a Sicilian population. Ann N Y Acad Sci 2006 0.81
96 Is there a relationship between insulin resistance and frailty syndrome? Curr Pharm Des 2008 0.81
97 Light and shadows of dietary protein restriction in elderly with chronic kidney disease. Nutrition 2013 0.81
98 Proteasome activity as a target of hormone replacement therapy-dependent plaque stabilization in postmenopausal women. Hypertension 2008 0.80
99 LL-paraoxonase genotype is associated with a more severe degree of homeostasis model assessment IR in healthy subjects. J Clin Endocrinol Metab 2002 0.80
100 Increased serum osteoprotegerin values in long-lived subjects: different effects of inflammation and bone metabolism. Eur J Endocrinol 2006 0.80
101 Effects of PPARs agonists on cardiac metabolism in littermate and cardiomyocyte-specific PPAR-γ-knockout (CM-PGKO) mice. PLoS One 2012 0.80
102 Positive association between circulating free insulin-like growth factor-1 levels and coronary flow reserve in arterial systemic hypertension. Am J Hypertens 2002 0.80
103 Lack of effect of aspirin in primary CV prevention in type 2 diabetic patients with nephropathy: results from 8 years follow-up of NID-2 study. Acta Diabetol 2014 0.79
104 Is the aging heart similar to the diabetic heart? Evaluation of LV function of the aging heart with Tissue Doppler Imaging. Aging Clin Exp Res 2009 0.79
105 Residual C-peptide secretion and endothelial function in patients with Type II diabetes. Clin Sci (Lond) 2003 0.79
106 Evidence for reduction of pro-atherosclerotic properties in platelets from healthy centenarians. Exp Gerontol 2003 0.79
107 Insulin therapy and lipid overload in type 2 diabetes. JAMA 2008 0.79
108 Raloxifene slows down the progression of intima-media thickness in postmenopausal women. Menopause 2007 0.79
109 Antidiabetic oral treatment in older people: does frailty matter? Drugs Aging 2009 0.79
110 Peri-procedural tight glycemic control during early percutaneous coronary intervention up-regulates endothelial progenitor cell level and differentiation during acute ST-elevation myocardial infarction: effects on myocardial salvage. Int J Cardiol 2013 0.78
111 Adiposity predicts cognitive decline in older persons with diabetes: a 2-year follow-up. PLoS One 2010 0.78
112 Role of subcutaneous abdominal fat on cardiac function and proinflammatory cytokines in premenopausal obese women. Ann Plast Surg 2009 0.78
113 Elevated plasma activator inhibitor 1 is not related to insulin resistance and to gene polymorphism in healthy centenarians. Atherosclerosis 2002 0.78
114 Study of the association with -330T/G IL-2 in a population of centenarians from centre and south Italy. Biogerontology 2005 0.78
115 Insulin resistance and cognitive decline may be common soil for frailty syndrome. Arch Intern Med 2007 0.78
116 Association of plasma selenium concentrations with total IGF-1 among older community-dwelling adults: the InCHIANTI study. Clin Nutr 2010 0.78
117 Relationship between baseline glycemic control and cognitive function in individuals with type 2 diabetes and other cardiovascular risk factors: the action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) trial: response to Cukierman-Yaffe et al. Diabetes Care 2009 0.77
118 Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity. Eur J Hum Genet 2010 0.77
119 Association of genetic variation in adaptor protein APPL1/APPL2 loci with non-alcoholic fatty liver disease. PLoS One 2013 0.77
120 A/ASP/VAL allele combination of IGF1R, IRS2, and UCP2 genes is associated with better metabolic profile, preserved energy expenditure parameters, and low mortality rate in longevity. Age (Dordr) 2011 0.76
121 Long term effects of low protein diet on depressive symptoms and quality of life in elderly Type 2 diabetic patients. Clin Nephrol 2012 0.76
122 Perspective: Dietary protein needs of elderly people: protein supplementation as an effective strategy to counteract sarcopenia. J Am Med Dir Assoc 2012 0.76
123 Prostate cancer treatment choices. Ann Intern Med 2013 0.75
124 Reply to the "Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations'", by Avogaro (Journal of Diabetes and Its Complications 25 [2011] 352-353). J Diabetes Complications 2011 0.75
125 Subclinical hypothyroidism and cardiovascular disease. Arch Intern Med 2012 0.75
126 Correspondence between the International Diabetes Federation criteria for metabolic syndrome and insulin resistance in a cohort of Italian nondiabetic Caucasians: the GISIR database. Diabetes Care 2007 0.75
127 Response to Comment on: Rizzo et al. Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition. Diabetes Care 2012;35:2076-2082. Diabetes Care 2013 0.75
128 Screening of depressive symptoms in young-old hemodialysis patients: relationship between Beck Depression Inventory and 15-item Geriatric Depression Scale. Nephron Clin Pract 2007 0.75
129 Cardiac electrophysiological alterations and clinical response in cardiac resynchronization therapy with a defibrillator treated patients affected by metabolic syndrome. Medicine (Baltimore) 2017 0.75
130 Shear stress as target to reduce atherosclerosis progression in hypertensive patients. Am J Hypertens 2008 0.75
131 Short-term effects of low-dose estrogen/drospirenone vs low-dose estrogen/dydrogesterone on glycemic fluctuations in postmenopausal women with metabolic syndrome. Age (Dordr) 2013 0.75
132 The PON1192RR genotype is associated with a higher prevalence of arterial hypertension. J Hypertens 2006 0.75
133 Adverse drug events in older geriatric patients: does safe prescribing exist? Drug Saf 2012 0.75
134 Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity. Biogerontology 2006 0.75
135 Adverse drug events in older geriatric patients: identifying the knowledge gaps to support research and clinical practice guidelines. Drug Saf 2012 0.75
136 Oral amino acid administration decreases oxidative stress and improves brachial reactivity in elderly individuals. Am J Hypertens 2005 0.75
137 Cryptogenic stroke and diabetes: a probable link between silent atrial fibrillation episodes and cerebrovascular disease. Expert Rev Cardiovasc Ther 2014 0.75
138 Clinical and biochemical evaluation changes over aging. Cancer Treat Res 2005 0.75
139 Implications of ABO blood group in hypertensive patients with covid-19. Res Sq 2020 0.75
140 Effect of tibolone administration on heart rate variability and free fatty acid levels in postmenopausal women. Fertil Steril 2002 0.75