Published in Dement Geriatr Cogn Disord on January 25, 2005
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci U S A (2008) 5.24
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol (2005) 4.91
The Alzheimer's disease beta-secretase enzyme, BACE1. Mol Neurodegener (2007) 1.81
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation (2010) 1.25
The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease. Curr Genomics (2007) 0.90
Expression of reticulon 3 in Alzheimer's disease brain. Neuropathol Appl Neurobiol (2009) 0.88
Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells. PLoS One (2013) 0.87
Astrocyte signaling and neurodegeneration: new insights into CNS disorders. Prion (2012) 0.86
Can BACE1 inhibition mitigate early axonal pathology in neurological diseases? J Alzheimers Dis (2014) 0.80
Enhancement of BACE1 Activity by p25/Cdk5-Mediated Phosphorylation in Alzheimer's Disease. PLoS One (2015) 0.80
Cerebrospinal fluid BACE1 activity and brain amyloid load in Alzheimer's disease. ScientificWorldJournal (2012) 0.75
Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence. Proc Natl Acad Sci U S A (2007) 1.80
Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease. Stroke (2002) 1.66
Perineuronal nets protect fast-spiking interneurons against oxidative stress. Proc Natl Acad Sci U S A (2013) 1.45
Patient satisfaction and side effects in primary care: an observational study comparing homeopathy and conventional medicine. BMC Complement Altern Med (2008) 1.34
Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment. PLoS One (2007) 1.33
Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors. J Neurosci (2010) 1.30
The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo. EMBO J (2006) 1.29
Early-life insults impair parvalbumin interneurons via oxidative stress: reversal by N-acetylcysteine. Biol Psychiatry (2012) 1.26
Glucocorticoid-related genetic susceptibility for Alzheimer's disease. Hum Mol Genet (2003) 1.11
Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: Relevance to schizophrenia. Neurobiol Dis (2006) 1.09
The role of the ubiquitin proteasome system in Alzheimer's disease. Exp Biol Med (Maywood) (2011) 1.05
Biochemical quantification of total brain glycogen concentration in rats under different glycemic states. Neurochem Int (2006) 1.03
Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress. Mol Cell Biol (2007) 1.03
Postsynaptic density protein PSD-95 expression in Alzheimer's disease and okadaic acid induced neuritic retraction. Neurobiol Dis (2008) 1.02
Differential changes in synaptic proteins in the Alzheimer frontal cortex with marked increase in PSD-95 postsynaptic protein. J Alzheimers Dis (2008) 1.01
Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo. J Neurosci Res (2006) 0.98
Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit. Neurobiol Dis (2006) 0.98
The immunoglobulin-superfamily molecule basigin is a binding protein for oligomannosidic carbohydrates: an anti-idiotypic approach. J Neurochem (2003) 0.97
Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease. J Neurosci (2009) 0.95
A comparison of learning and memory characteristics of young and middle-aged wild-type mice in the IntelliCage. J Neurosci Methods (2009) 0.95
Genetic dysregulation of glutathione synthesis predicts alteration of plasma thiol redox status in schizophrenia. Antioxid Redox Signal (2010) 0.93
Antibodies from a DNA peptide vaccination decrease the brain amyloid burden in a mouse model of Alzheimer's disease. J Mol Med (Berl) (2004) 0.93
Structural basis for map formation in the thalamocortical pathway of the barrelless mouse. J Neurosci (2006) 0.91
Antibody-based approaches in Alzheimer's research: safety, pharmacokinetics, metabolism, and analytical tools. J Neurochem (2007) 0.90
Brain imaging and human nutrition: which measures to use in intervention studies? Br J Nutr (2013) 0.89
Myotonic dystrophy transgenic mice exhibit pathologic abnormalities in diaphragm neuromuscular junctions and phrenic nerves. J Neuropathol Exp Neurol (2008) 0.87
Decreased behavioral impairments in an Alzheimer mice model by interfering with TNF-alpha metabolism. Brain Res Bull (2009) 0.86
Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. Brain Struct Funct (2014) 0.84
Peripheral neuropathy is linked to a severe form of myotonic dystrophy in transgenic mice. J Neuropathol Exp Neurol (2011) 0.82
Specific inhibition of the JNK pathway promotes locomotor recovery and neuroprotection after mouse spinal cord injury. Neurobiol Dis (2012) 0.81
Increased postsynaptic density protein-95 expression in the frontal cortex of aged cognitively impaired rats. Exp Biol Med (Maywood) (2012) 0.80
Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease. Curr Alzheimer Res (2014) 0.80
Intracortical connectivity of layer VI pyramidal neurons in the somatosensory cortex of normal and barrelless mice. Eur J Neurosci (2012) 0.80
Active immunization trial in Abeta42-injected P301L tau transgenic mice. Neurobiol Dis (2005) 0.79
Expression of brain-derived neurotrophic factor is not modulated by chronic mild stress in the rat hippocampus and amygdala. Pharmacol Rep (2009) 0.79
A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons. Free Radic Biol Med (2007) 0.79
Active immunization of mice with an Abeta-Hsp70 vaccine. Neurodegener Dis (2004) 0.79
Thyroid hormone reduces the loss of axotomized sensory neurons in dorsal root ganglia after sciatic nerve transection in adult rat. Exp Neurol (2003) 0.79
No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis. J Gen Virol (2005) 0.78
Cerebrospinal fluid antimicroglial antibodies in Alzheimer disease: a putative marker of an ongoing inflammatory process. Exp Gerontol (2006) 0.78
Retracted Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice. Neurochem Res (2008) 0.78
Monoamine reuptake inhibition and mood-enhancing potential of a specified oregano extract. Br J Nutr (2010) 0.77
Differential damage in the frontal cortex with aging, sporadic and familial Alzheimer's disease. Brain Res Bull (2009) 0.77
Challenges in discovering bioactives for the food industry. Curr Opin Biotechnol (2008) 0.77
GABA receptor subunits in human auditory cortex in normal and stroke cases. Acta Neurobiol Exp (Wars) (2009) 0.77
Food-derived serotonergic modulators: effects on mood and cognition. Nutr Res Rev (2013) 0.76
Modulation of Alzheimer's pathology by cerebro-ventricular grafting of hybridoma cells expressing antibodies against Abeta in vivo. FEBS Lett (2005) 0.76
Food can lift mood by affecting mood-regulating neurocircuits via a serotonergic mechanism. Neuroimage (2013) 0.76
Thyroid hormone in biodegradable nerve guides stimulates sciatic nerve regeneration: a potential therapeutic approach for human peripheral nerve injuries. J Neurotrauma (2007) 0.76
The impact of missense mutations on human behavior. Brain Res Bull (2012) 0.75
Does the physical disector method provide an accurate estimation of sensory neuron number in rat dorsal root ganglia? J Neurosci Methods (2008) 0.75
Impairment and disability in 20 CIDP patients according to disease activity status. J Peripher Nerv Syst (2013) 0.75