1
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Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
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Oncogene
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2004
|
2.82
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2
|
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
|
Oncogene
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2003
|
2.79
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3
|
Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer.
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Nat Genet
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2005
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2.08
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4
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NF-κB2/p52 induces resistance to enzalutamide in prostate cancer: role of androgen receptor and its variants.
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Mol Cancer Ther
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2013
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1.81
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5
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Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells.
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Clin Cancer Res
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2003
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1.80
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6
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Interleukin-6 polymorphism is associated with more aggressive prostate cancer.
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J Urol
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2005
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1.69
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7
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Stat3 activation in prostatic carcinomas.
|
Prostate
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2002
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1.61
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8
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Prostate-specific antigen modulates genes involved in bone remodeling and induces osteoblast differentiation of human osteosarcoma cell line SaOS-2.
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Clin Cancer Res
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2006
|
1.58
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9
|
Lin28 promotes growth of prostate cancer cells and activates the androgen receptor.
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Am J Pathol
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2013
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1.53
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10
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MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells.
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J Biol Chem
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2011
|
1.52
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11
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Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation.
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Proc Natl Acad Sci U S A
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2006
|
1.46
|
12
|
Prostate specific antigen expression is down-regulated by selenium through disruption of androgen receptor signaling.
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Cancer Res
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2004
|
1.33
|
13
|
Interleukin-6 regulates androgen synthesis in prostate cancer cells.
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Clin Cancer Res
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2009
|
1.32
|
14
|
MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth.
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PLoS One
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2012
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1.30
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15
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Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells.
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Cancer Res
|
2010
|
1.29
|
16
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Molecular mechanisms of castration-resistant prostate cancer progression.
|
Future Oncol
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2009
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1.26
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17
|
Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers.
|
Mol Cancer Ther
|
2005
|
1.26
|
18
|
Interleukin-6 undergoes transition from growth inhibitor associated with neuroendocrine differentiation to stimulator accompanied by androgen receptor activation during LNCaP prostate cancer cell progression.
|
Prostate
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2007
|
1.23
|
19
|
NF-kappaB2/p52 enhances androgen-independent growth of human LNCaP cells via protection from apoptotic cell death and cell cycle arrest induced by androgen-deprivation.
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Prostate
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2008
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1.21
|
20
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Selective activation of members of the signal transducers and activators of transcription family in prostate carcinoma.
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J Urol
|
2002
|
1.20
|
21
|
RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells.
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Prostate
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2004
|
1.15
|
22
|
Interleukin-6 protects LNCaP cells from apoptosis induced by androgen deprivation through the Stat3 pathway.
|
Prostate
|
2004
|
1.14
|
23
|
Functional p53 determines docetaxel sensitivity in prostate cancer cells.
|
Prostate
|
2012
|
1.10
|
24
|
Hypoxia increases androgen receptor activity in prostate cancer cells.
|
Cancer Res
|
2006
|
1.09
|
25
|
Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA).
|
Prostate
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2006
|
1.07
|
26
|
Microarray analysis reveals potential target genes of NF-kappaB2/p52 in LNCaP prostate cancer cells.
|
Prostate
|
2010
|
1.05
|
27
|
Lack of expression of androgen receptor may play a critical role in transformation from in situ to invasive basal subtype of high-grade ductal carcinoma of the breast.
|
Hum Pathol
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2008
|
1.04
|
28
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Inhibition of ABCB1 expression overcomes acquired docetaxel resistance in prostate cancer.
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Mol Cancer Ther
|
2013
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1.03
|
29
|
Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2.
|
Mol Cancer Ther
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2009
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1.02
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30
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Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop.
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Mol Cell Biol
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2012
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1.02
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31
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Sanguinarine suppresses prostate tumor growth and inhibits survivin expression.
|
Genes Cancer
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2010
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1.01
|
32
|
Interleukin-4 stimulates androgen-independent growth in LNCaP human prostate cancer cells.
|
Prostate
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2008
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1.00
|
33
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Mechanisms of persistent activation of the androgen receptor in CRPC: recent advances and future perspectives.
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World J Urol
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2011
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0.99
|
34
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Microarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer.
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Cancer Genomics Proteomics
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2005
|
0.99
|
35
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Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells.
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Prostate
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2005
|
0.99
|
36
|
Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells.
|
Prostate
|
2013
|
0.98
|
37
|
Stat3 enhances the growth of LNCaP human prostate cancer cells in intact and castrated male nude mice.
|
Prostate
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2002
|
0.98
|
38
|
Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST).
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Prostate
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2014
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0.98
|
39
|
Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion.
|
Prostate
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2011
|
0.97
|
40
|
Andrographolide targets androgen receptor pathway in castration-resistant prostate cancer.
|
Genes Cancer
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2011
|
0.96
|
41
|
Selenium inhibition of survivin expression by preventing Sp1 binding to its promoter.
|
Mol Cancer Ther
|
2007
|
0.96
|
42
|
Mechanisms of selenium down-regulation of androgen receptor signaling in prostate cancer.
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Mol Cancer Ther
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2006
|
0.93
|
43
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Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway.
|
Oncogene
|
2003
|
0.93
|
44
|
Stat3 enhances transactivation of steroid hormone receptors.
|
Nucl Recept
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2003
|
0.92
|
45
|
LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway.
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Biochem Biophys Res Commun
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2007
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0.91
|
46
|
Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model.
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Mol Cancer Ther
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2010
|
0.90
|
47
|
Mechanisms of selenium chemoprevention and therapy in prostate cancer.
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Mol Nutr Food Res
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2008
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0.87
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48
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Selenium disrupts estrogen signaling by altering estrogen receptor expression and ligand binding in human breast cancer cells.
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Cancer Res
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2005
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0.87
|
49
|
RhoGDIα suppresses growth and survival of prostate cancer cells.
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Prostate
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2011
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0.86
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50
|
Upregulation of glucose metabolism by NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells.
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Endocr Relat Cancer
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2014
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0.86
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51
|
Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex.
|
Prostate
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2012
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0.85
|
52
|
Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth.
|
Genes Cancer
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2010
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0.83
|
53
|
Development of an androgen-deprivation induced and androgen suppressed human prostate cancer cell line.
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Prostate
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2007
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0.82
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54
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Effects of triclocarban on intact immature male rat: augmentation of androgen action.
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Reprod Sci
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2010
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0.81
|
55
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Interleukin-4 activates androgen receptor through CBP/p300.
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Prostate
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2009
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0.81
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56
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LNCaP prostate cancer cells with autocrine interleukin-6 expression are resistant to IL-6-induced neuroendocrine differentiation due to increased expression of suppressors of cytokine signaling.
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Prostate
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2011
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0.80
|
57
|
RhoGDIα downregulates androgen receptor signaling in prostate cancer cells.
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Prostate
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2013
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0.80
|
58
|
The interleukin 6 receptor is a direct transcriptional target of E2F3 in prostate tumor derived cells.
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Prostate
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2011
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0.78
|
59
|
STAT3 and transactivation of steroid hormone receptors.
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Vitam Horm
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2005
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0.78
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60
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Intracellular glutathione content influences the sensitivity of lung cancer cell lines to methylseleninic acid.
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Mol Carcinog
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2011
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0.77
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61
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Transcriptional regulation of human RANK ligand gene expression by E2F1.
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Biochem Biophys Res Commun
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2008
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0.76
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62
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Regulation of androgen and vitamin d receptors by 1,25-dihydroxyvitamin D3 in human prostate epithelial and stromal cells.
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J Urol
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2003
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0.75
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63
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[Primary experimental results of methylseleninic acid on the proliferation inhibition and apoptotic induction in human high-metastatic large cell lung cancer cell line L9981].
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Zhongguo Fei Ai Za Zhi
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2006
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0.75
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64
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Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer.
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Nat Med
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2016
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0.75
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65
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[Combined Inhibition of Vascular Endothelial Growth Factor and Epidermal Growth Factor Signaling Pathways in Non-small Cell Lung Cancer Therapy.].
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Zhongguo Fei Ai Za Zhi
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2009
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0.75
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