PubRank

Kohzoh Imai

Author PubWeight™ 241.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004 7.78
2 Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 2003 4.80
3 Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 2008 3.81
4 Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet 2007 3.39
5 Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors. Cancer Res 2012 2.45
6 Defining the critical hurdles in cancer immunotherapy. J Transl Med 2011 2.32
7 A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma. Am J Gastroenterol 2012 2.06
8 Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs. Oncogene 2003 1.91
9 A new conceptualization for Mikulicz's disease as an IgG4-related plasmacytic disease. Mod Rheumatol 2006 1.91
10 DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer. Gastroenterology 2008 1.83
11 Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers. Oncogene 2005 1.82
12 Clinical and pathological characteristics of Mikulicz's disease (IgG4-related plasmacytic exocrinopathy). Autoimmun Rev 2004 1.80
13 Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status. Hum Mol Genet 2004 1.66
14 Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia. Blood 2003 1.65
15 BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes. Oncogene 2005 1.62
16 Risk of malignancies in IgG4-related disease. Mod Rheumatol 2011 1.61
17 Pathologic features of mucin-producing bile duct tumors: two histopathologic categories as counterparts of pancreatic intraductal papillary-mucinous neoplasms. Am J Surg Pathol 2004 1.59
18 Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta. EMBO J 2002 1.59
19 Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer. Clin Cancer Res 2005 1.58
20 Epigenetic inactivation of CHFR in human tumors. Proc Natl Acad Sci U S A 2003 1.57
21 Intractable colitis associated with chronic granulomatous disease. J Med Microbiol 2006 1.56
22 New classification of pancreatic intraductal papillary-mucinous tumour by mucin expression: its relationship with potential for malignancy. J Pathol 2002 1.54
23 The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis. J Gastroenterol 2003 1.53
24 Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors. Carcinogenesis 2007 1.52
25 Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. Carcinogenesis 2010 1.52
26 Circulating anti-MUC1 IgG antibodies as a favorable prognostic factor for pancreatic cancer. Int J Cancer 2003 1.51
27 The p53 family member genes are involved in the Notch signal pathway. J Biol Chem 2001 1.50
28 MUC4 is a novel prognostic factor of extrahepatic bile duct carcinoma. Clin Cancer Res 2006 1.46
29 MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type. Hepatology 2004 1.43
30 Usefulness of narrow-band imaging endoscopy for diagnosis of Barrett's esophagus. J Gastroenterol 2004 1.40
31 Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer. Cancer Res 2011 1.40
32 Tophaceous gout in the cervical spine. Intern Med 2012 1.40
33 Classification of Barrett's epithelium by magnifying endoscopy. Gastrointest Endosc 2002 1.40
34 Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus. Cancer 2006 1.37
35 IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis 2009 1.34
36 Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases. Mod Rheumatol 2011 1.33
37 Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology. J Transl Med 2009 1.31
38 Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer. World J Gastroenterol 2012 1.31
39 The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. Gastroenterology 2005 1.30
40 Frizzled-7 as a potential therapeutic target in colorectal cancer. Neoplasia 2008 1.28
41 Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer. Cancer Res 2003 1.27
42 Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors. Cancer Res 2005 1.26
43 Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. J Gastroenterol 2008 1.25
44 Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors. Oncogene 2002 1.23
45 MUC4 expression correlates with poor prognosis in small-sized lung adenocarcinoma. Lung Cancer 2006 1.22
46 PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer. Clin Cancer Res 2007 1.21
47 Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation. Cancer Res 2006 1.21
48 Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer. Cancer Res 2007 1.20
49 Gene amplification and overexpression of PRDM14 in breast cancers. Cancer Res 2007 1.18
50 Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype. Am J Pathol 2012 1.17
51 Genetic blockade of the insulin-like growth factor-I receptor: a promising strategy for human pancreatic cancer. Cancer Res 2003 1.16
52 Identification of SCN3B as a novel p53-inducible proapoptotic gene. Oncogene 2004 1.16
53 Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer. Cancer Sci 2007 1.14
54 A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors. Clin Cancer Res 2010 1.14
55 Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis. Clin Cancer Res 2004 1.13
56 The birthday of a new syndrome: IgG4-related diseases constitute a clinical entity. Autoimmun Rev 2010 1.12
57 Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex. Gastroenterology 2005 1.12
58 Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling. Cancer Res 2007 1.11
59 Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer. J Pathol 2003 1.11
60 Epigenetic inactivation of TMS1/ASC in ovarian cancer. Clin Cancer Res 2004 1.11
61 Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis. Eur J Cancer 2006 1.09
62 Association of ets-related transcriptional factor E1AF expression with tumour progression and overexpression of MMP-1 and matrilysin in human colorectal cancer. J Pathol 2003 1.09
63 A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells. Cancer Res 2008 1.08
64 CCL8 is a potential molecular candidate for the diagnosis of graft-versus-host disease. Blood 2008 1.08
65 LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis. Cancer Epidemiol Biomarkers Prev 2008 1.08
66 Gastrointestinal cancer of the microsatellite mutator phenotype pathway. J Gastroenterol 2002 1.08
67 Aberrant methylation and histone deacetylation associated with silencing of SLC5A8 in gastric cancer. Tumour Biol 2004 1.08
68 Genetic and epigenetic profiling in early colorectal tumors and prediction of invasive potential in pT1 (early invasive) colorectal cancers. Carcinogenesis 2006 1.07
69 Histone deacetylase inhibitors FK228, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)amino- methyl]benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells. Int J Cancer 2004 1.06
70 Increased expression of MUC1 in advanced pancreatic cancer. J Gastroenterol 2003 1.06
71 Activation of the ribosomal protein L13 gene in human gastrointestinal cancer. Int J Mol Med 2006 1.06
72 Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity. J Pathol 2009 1.04
73 Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells. Oncogene 2004 1.04
74 Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability. Genes Chromosomes Cancer 2002 1.04
75 Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies. Cancer Res 2009 1.03
76 Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma. Clin Cancer Res 2009 1.03
77 A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth. BMC Cancer 2009 1.02
78 Insulin-like growth factor-I receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma. Carcinogenesis 2006 1.02
79 Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. Int J Cancer 2002 1.01
80 Differential expression of angiogenesis-related genes in human gastric cancers with and those without high-frequency microsatellite instability. Cancer Lett 2007 1.01
81 Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers. World J Gastroenterol 2008 1.01
82 Differential roles of alterations of p53, p16, and SMAD4 expression in the progression of intraductal papillary-mucinous tumors of the pancreas. Oncol Rep 2002 1.01
83 Analysis of serum IgG subclasses in Churg-Strauss syndrome--the meaning of elevated serum levels of IgG4. Intern Med 2010 1.01
84 Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas. Mod Pathol 2006 1.00
85 Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer. Eur Urol 2012 1.00
86 Carcinoma of duodenum arising from Brunner's gland. J Gastroenterol 2002 1.00
87 A candidate targeting molecule of insulin-like growth factor-I receptor for gastrointestinal cancers. World J Gastroenterol 2010 0.99
88 Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin. Carcinogenesis 2009 0.99
89 Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. Carcinogenesis 2005 0.98
90 DNA methylation and cancer pathways in gastrointestinal tumors. Pharmacogenomics 2008 0.97
91 Association of matrilysin-2 (MMP-26) expression with tumor progression and activation of MMP-9 in esophageal squamous cell carcinoma. Carcinogenesis 2004 0.97
92 Diaphragm disease of small intestine diagnosed by double-balloon enteroscopy. Gastrointest Endosc 2005 0.97
93 Cancer epigenomics: implications of DNA methylation in personalized cancer therapy. Cancer Sci 2009 0.97
94 Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. J Gastroenterol 2005 0.96
95 MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer. Anticancer Res 2005 0.96
96 [A case of acute phase ulcerative colitis like colitis developed by the interferon-beta therapy for chronic hepatitis C]. Nihon Shokakibyo Gakkai Zasshi 2003 0.96
97 Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: results from the SMART database. Mod Rheumatol 2014 0.95
98 Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma. Cancer Sci 2008 0.95
99 MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions. Int J Cancer 2014 0.95
100 Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer. Carcinogenesis 2008 0.95
101 Clinicopathologic similarities between Mikulicz disease and Küttner tumor. Am J Otolaryngol 2009 0.95
102 Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma. Tumour Biol 2012 0.94
103 A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells. Clin Cancer Res 2009 0.94
104 Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer. Cancer Prev Res (Phila) 2012 0.94
105 Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. Mod Pathol 2011 0.94
106 Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity. Clin Cancer Res 2005 0.93
107 DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae. Cancer Sci 2010 0.93
108 Histone deacetylase inhibitors enhance phosphorylation of histone H2AX after ionizing radiation. Int J Radiat Oncol Biol Phys 2006 0.92
109 A case-control study of multiple myeloma in Japan: association with occupational factors. Asian Pac J Cancer Prev 2005 0.92
110 Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta-catenin protein. Oncogene 2005 0.92
111 Gastropleural fistula derived from malignant lymphoma. J Gastroenterol 2002 0.92
112 Insulin-like growth factor-I receptor blockade reduces tumor angiogenesis and enhances the effects of bevacizumab for a human gastric cancer cell line, MKN45. Cancer 2011 0.92
113 Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer. Cancer Sci 2013 0.91
114 Necessity of early intervention for IgG4-related disease--delayed treatment induces fibrosis progression. Rheumatology (Oxford) 2012 0.91
115 Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors. Cancer Biol Ther 2005 0.91
116 A pancreatic abscess 7 years after a pancreatojejunostomy for calcifying chronic pancreatitis. J Gastroenterol 2002 0.91
117 Identification of the osteopontin gene as a direct target of TP53. Genes Chromosomes Cancer 2002 0.91
118 The immunobiology and clinical characteristics of IgG4 related diseases. J Autoimmun 2012 0.91
119 Expression of ets-related transcriptional factor E1AF is associated with tumor progression and over-expression of matrilysin in human gastric cancer. Carcinogenesis 2003 0.90
120 Monoclonal antibodies as effective therapeutic agents for solid tumors. Cancer Sci 2004 0.90
121 Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity. Apoptosis 2006 0.90
122 Leukoencephalopathy during administration of etanercept for refractory rheumatoid arthritis. Mod Rheumatol 2007 0.90
123 Oxidative stress impairs the heat stress response and delays unfolded protein recovery. PLoS One 2009 0.90
124 Cysteinyl leukotriene receptor antagonists inhibit tumor metastasis by inhibiting capillary permeability. Keio J Med 2010 0.89
125 Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer. Clin Cancer Res 2003 0.89
126 Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat. J Gastroenterol 2010 0.89
127 Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes. Oncogene 2005 0.88
128 Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation. Apoptosis 2006 0.88
129 Identification of flotillin-2, a major protein on lipid rafts, as a novel target of p53 family members. Mol Cancer Res 2008 0.88
130 Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells. Clin Cancer Res 2004 0.88
131 [A case of pityriasis rubra pilaris associated with rapidly progressive finger joint destruction]. Nihon Rinsho Meneki Gakkai Kaishi 2004 0.88
132 [The significance of disease-independence in Mikulicz's disease--revival interests in Mikulicz's disease]. Nihon Rinsho Meneki Gakkai Kaishi 2006 0.88
133 Microsatellite instability: an update. Arch Toxicol 2015 0.88
134 Mesenchymal stem cells cancel azoxymethane-induced tumor initiation. Stem Cells 2014 0.87
135 Antisense therapy of MAdCAM-1 for trinitrobenzenesulfonic acid-induced murine colitis. Inflamm Bowel Dis 2006 0.87
136 Clonotypic analysis of T cells accumulating at arthritic lesions in HTLV-I env-pX transgenic rats. Exp Mol Pathol 2002 0.86
137 Identification of the interleukin 4 receptor alpha gene as a direct target for p73. Cancer Res 2003 0.86
138 Relapse patterns in IgG4-related disease. Ann Rheum Dis 2012 0.86
139 Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas. Mol Cancer Ther 2008 0.86
140 Detection of the four sequence variations of MDR1 gene using TaqMan MGB probe based real-time PCR and haplotype analysis in healthy Japanese subjects. Clin Biochem 2003 0.86
141 Overexpression of beta3/gamma2 chains of laminin-5 and MMP7 in biliary cancer. World J Gastroenterol 2009 0.86
142 Forecasting Japan's physician shortage in 2035 as the first full-fledged aged society. PLoS One 2012 0.86
143 Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer. Ann Surg Oncol 2014 0.86
144 Haplotype analysis of UDP-glucuronocyltransferase 2B7 gene (UGT2B7) polymorphisms in healthy Japanese subjects. Clin Biochem 2006 0.86
145 Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors. J Gastroenterol 2013 0.85
146 Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth. Cancer Sci 2008 0.85
147 The antisense approach in amyloid light chain amyloidosis: identification of monoclonal Ig and inhibition of its production by antisense oligonucleotides in in vitro and in vivo models. J Immunol 2002 0.85
148 The use of bone marrow stromal cells (bone marrow-derived multipotent mesenchymal stromal cells) for alveolar bone tissue engineering: basic science to clinical translation. Tissue Eng Part B Rev 2014 0.85
149 [SFRP, a family of new colorectal tumor suppressor candidate genes]. Nihon Rinsho 2005 0.84
150 Genetic variants in surfactant, pulmonary-associated protein D (SFTPD) and Japanese susceptibility to ulcerative colitis. Inflamm Bowel Dis 2009 0.84
151 Targeting for insulin-like growth factor-I receptor with short hairpin RNA for human digestive/gastrointestinal cancers. J Gastroenterol 2009 0.84
152 The efficacy of IGF-I receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status. Clin Cancer Res 2011 0.84
153 [A case of pseudoscleroderma as paraneoplastic syndrome due to carcinoma of cervical uteri]. Nihon Rinsho Meneki Gakkai Kaishi 2003 0.84
154 Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer. Int J Oncol 2011 0.84
155 Mucin expression profile is related to biological and clinical characteristics of intraductal papillary-mucinous tumors of the pancreas. Pancreas 2005 0.83
156 Increased cyclooxygenase-2 expression in large flat colorectal tumors (laterally spreading tumors). J Gastroenterol 2003 0.83
157 Possible involvement of Wnt11 in colorectal cancer progression. Mol Carcinog 2011 0.83
158 Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins. Am J Pathol 2006 0.83
159 2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun NH2-terminal kinase activation. Clin Cancer Res 2006 0.83
160 Mutational analysis of beta-catenin and the RAS-RAF signalling pathway in early flat-type colorectal tumours. Eur J Cancer 2006 0.83
161 Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization. Genes Chromosomes Cancer 2012 0.83
162 Mucin phenotype and microsatellite instability in early multiple gastric cancers. Int J Cancer 2002 0.83
163 [Plasma analysis of rheumatoid arthritis by SELDI]. Nihon Rinsho Meneki Gakkai Kaishi 2007 0.83
164 Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk. J Gastroenterol 2013 0.82
165 Combination of tumor necrosis factor-alpha with sulindac in human carcinoma cells in vivo. Ann N Y Acad Sci 2003 0.82
166 Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids. World J Gastroenterol 2013 0.82
167 [A case of lupus erythematosus profundus followed by systemic lupus erythematosus presenting with severe intestinal involvement]. Nihon Rinsho Meneki Gakkai Kaishi 2007 0.82
168 Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models. Mol Cancer Ther 2008 0.82
169 Combination of tumor necrosis factor-alpha with sulindac augments its apoptotic potential and suppresses tumor growth of human carcinoma cells in nude mice. Cancer 2003 0.82
170 Interferon gamma assay for detecting latent tuberculosis infection in rheumatoid arthritis patients during infliximab administration. Rheumatol Int 2007 0.82
171 Characteristics of Japanese inflammatory bowel disease susceptibility loci. J Gastroenterol 2013 0.81
172 Expression of CD66a in multiple myeloma. J Clin Lab Anal 2002 0.81
173 A highly effective and stable bispecific diabody for cancer immunotherapy: cure of xenografted tumors by bispecific diabody and T-LAK cells. Cancer Immunol Immunother 2003 0.81
174 Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma. World J Gastroenterol 2010 0.81
175 Aberrant expression of pyloric gland-type mucin in mucin-producing bile duct carcinomas: a clear difference between the core peptide and the carbohydrate moiety. Pathol Int 2005 0.81
176 Regulation of MHC class II expression in glioma cells by class II transactivator (CIITA). Glia 2004 0.80
177 Development of human-human hybridoma from anti-Her-2 peptide-producing B cells in immunized NOG mouse. Exp Hematol 2006 0.80
178 In vitro and in vivo antitumor effects of recombinant bispecific antibodies based on humanized anti-EGFR antibody. Oncol Rep 2011 0.80
179 Novel molecular-targeted therapeutics for the treatment of cancer. Anticancer Agents Med Chem 2008 0.80
180 Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors. Cancer Prev Res (Phila) 2011 0.80
181 The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma. Tumour Biol 2013 0.80
182 [A case of scleroderma-polymyositis overlap syndrome in which octreotide exacerbated abdominal symptoms]. Nihon Rinsho Meneki Gakkai Kaishi 2005 0.80
183 Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo. PLoS One 2011 0.80
184 Genetic and epigenetic characteristics of gastric cancers with JC virus T-antigen. World J Gastroenterol 2009 0.80
185 Overexpression of BAD preferentially augments anoikis. Int J Cancer 2003 0.80
186 Long-term outcomes and necessity of early intervention for IgG4-related disease. Nihon Rinsho Meneki Gakkai Kaishi 2013 0.79
187 p53 family members regulate the expression of the apolipoprotein D gene. J Biol Chem 2008 0.79
188 The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents. Int J Oncol 2005 0.79
189 Phenotypic alteration of interstitial cells of Cajal in idiopathic sigmoid megacolon. J Gastroenterol 2008 0.79
190 Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan. Dis Colon Rectum 2008 0.78
191 A case of pneumatosis cystoides intestinalis with dermatomyositis in which EUS was useful for the diagnosis. Int J Colorectal Dis 2004 0.78
192 Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients. Digestion 2015 0.78
193 Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand. Int J Oncol 2005 0.78
194 Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers. Cancer Sci 2011 0.78
195 [A case of Mikulicz's disease complicated by autoimmune pancreatitis, in which impaired glucose tolerance was improved by glucocorticoid treatment]. Nihon Rinsho Meneki Gakkai Kaishi 2005 0.78
196 A mutated superantigen SEA D227A fusion diabody specific to MUC1 and CD3 in targeted cancer immunotherapy for bile duct carcinoma. Cancer Immunol Immunother 2002 0.78
197 Heat stress activates ER stress signals which suppress the heat shock response, an effect occurring preferentially in the cortex in rats. Mol Biol Rep 2011 0.78
198 DNA synthesis inhibitors for the treatment of gastrointestinal cancer. Expert Opin Pharmacother 2014 0.78
199 Correlation of laterally spreading type and JC virus with methylator phenotype status in colorectal adenoma. Hum Pathol 2008 0.78
200 DNA methylation changes in gastrointestinal disease. J Gastroenterol 2002 0.78
201 [Hemorrhage from varices of an interposed jejunum after choledochojejunostomy successfully treated by transileocolic vein obliteration]. Nihon Shokakibyo Gakkai Zasshi 2008 0.77
202 Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer. Tumour Biol 2012 0.77
203 Anti-tumor activity of dendritic cells transfected with mRNA for receptor for hyaluronan-mediated motility is mediated by CD4+ T cells. Cancer Immunol Immunother 2005 0.77
204 Analysis of gene expression in human colorectal cancer tissues by cDNA array. J Gastroenterol 2002 0.77
205 Evaluation and Clinical Validity of a New Questionnaire for Mikulicz's Disease. Int J Rheumatol 2012 0.77
206 [A case of AFP and PIVKA-II producing gastric carcinoma]. Nihon Shokakibyo Gakkai Zasshi 2006 0.77
207 Accumulation of Hsp70/Hsc70 molecular chaperone regulator BAG-1 on COPI-coated structures in gastric epithelial cells. Int J Oncol 2003 0.77
208 A case of colorectal carcinoma in adenoma analyzed by a cDNA array. Int J Colorectal Dis 2004 0.77
209 Therapeutic effect of dendritic cells loaded with a fusion mRNA encoding tyrosinase-related protein 2 and enhanced green fluorescence protein on B16 melanoma. Tumour Biol 2005 0.77
210 [A case of gastric mucosal bridge with Behçet's disease]. Nihon Rinsho Meneki Gakkai Kaishi 2004 0.77
211 Occludin modulates organization of perijunctional circumferential actin in rat endothelial cells. Med Electron Microsc 1999 0.77
212 Image of the month. A gastric heterotopic pancreas with cystic change. Gastroenterology 2005 0.77
213 Can DNA methylation be a molecular marker for eradication of Helicobacter pylori in MALT lymphoma? J Gastroenterol 2002 0.77
214 In the forefront of basic and translational cancer research: Seventh Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association. Cancer Res 2007 0.76
215 Combination therapy of DDAVP and conjugated estrogens for a recurrent large subcutaneous hematoma in Ehlers-Danlos syndrome. Am J Hematol 2003 0.76
216 [Beneficial effect of glucocorticosteroids for esophageal varices due to idiopathic portal hypertension following systemic lupus erythematosus]. Nihon Rinsho Meneki Gakkai Kaishi 2004 0.76
217 Increased expression of T-fimbrin gene after DNA damage in CHO cells and inactivation of T-fimbrin by CpG methylation in human colorectal cancer cells. Int J Cancer 2002 0.76
218 Mikulicz's disease and systemic IgG4-related plasmacytic syndrome (SIPS). Nihon Rinsho Meneki Gakkai Kaishi 2008 0.75
219 Hepatitis B virus-associated aplastic anemia followed by myelodysplastic syndrome. Am J Med 2002 0.75
220 Haploinsufficiency in multiploid colorectal cancer. J Gastroenterol 2005 0.75
221 Detection of fecal interferon-induced transmembrane protein messenger RNA for colorectal cancer screening. Oncol Lett 2010 0.75
222 The management of gastrointestinal infections caused by cytomegalovirus. J Gastroenterol 2003 0.75
223 Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards. Springerplus 2013 0.75
224 Antitumor effect of new HER2 peptide vaccination based on B cell epitope. Anticancer Res 2011 0.75
225 Silencing of negative regulator of JAK/STAT in colorectal cancer. J Gastroenterol 2004 0.75
226 The enigma of intestinal subepithial myofibroblast still remains to be resolved. J Gastroenterol 2003 0.75
227 Gigantic gastrointestinal stromal tumor in the pelvis. Int J Colorectal Dis 2004 0.75
228 Association between morphology and molecular changes in colorectal cancer. J Gastroenterol 2002 0.75
229 Model of translational cancer research in multiple myeloma. Cancer Sci 2012 0.75
230 Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model. J Gastroenterol 2015 0.75
231 Integrated analysis of genetic and epigenetic alterations in cancer. Epigenomics 2009 0.75
232 [Clinical application of DNA array system in human gastrointestinal cancer]. Hokkaido Igaku Zasshi 2002 0.75
233 [A case of rheumatoid arthritis/Sjogren's syndrome with acute renal failure due to hyperuricemia associated with mizoribine therapy]. Nihon Rinsho Meneki Gakkai Kaishi 2004 0.75
234 [A case in which the subject was affected by Listeia meningoencephalitis during administration of infliximab for steroid-dependent adult onset Still's disease]. Nihon Rinsho Meneki Gakkai Kaishi 2006 0.75
235 The role of cytotoxic T cells in IgG4-related dacryoadenitis and sialadenitis, the so-called Mikulicz's disease. Mod Rheumatol 2014 0.75
236 A simple immunomonitoring procedure for mRNA-loaded dendritic cell therapy. Tumour Biol 2008 0.75
237 Adult-onset Still's disease in pregnancy. Mod Rheumatol 2011 0.75
238 [Monoclonal antibody induces apoptosis against cancer cells]. Nihon Rinsho 2002 0.75
239 [Monoclonal antibody therapy for disorders of hemostasis and coagulation]. Nihon Rinsho 2002 0.75
240 Antiproliferation and apoptosis on RKO colon cancer by Millingtonia hortensis. Plant Foods Hum Nutr 2009 0.75
241 [Nonspecific cross-reacting antigen (NCA)--carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)]. Nihon Rinsho 2010 0.75
242 [Gastric cancer and microsatellite instability]. Nihon Shokakibyo Gakkai Zasshi 2002 0.75
243 [A case of follicular lymphoma of the duodenum treated with the combined therapy of anti-CD20 antibody and chemotherapy]. Nihon Shokakibyo Gakkai Zasshi 2006 0.75
244 New approaches to identification of biomarkers for early cancer detection: The Thirteenth International Symposium of the Hiroshima Cancer Seminar, October 2003. Cancer Sci 2004 0.75
245 [Usefulness of measuring serum IgG4 level as diagnostic and treatment marker in IgG4-related disease]. Nihon Rinsho Meneki Gakkai Kaishi 2012 0.75
246 De novo CD5-positive diffuse large B cell lymphoma solely presenting as multiple subcutaneous nodules. Acta Haematol 2002 0.75
247 [A case of alveolar hydatid disease of the liver for which progression was seen on CT images]. Nihon Shokakibyo Gakkai Zasshi 2007 0.75
248 [Overview of recent monoclonal antibody therapy]. Nihon Rinsho 2002 0.75
249 Mucormycosis as an etiology of cerebral hemorrhage in patients with chronic neutrophilic leukemia. Am J Med 2003 0.75
250 A case of systemic lupus erythematosus with postpartum hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome and concomitant high phosphatidylserine-dependent anti-prothrombin antibody levels. Mod Rheumatol 2004 0.75
251 [The expression technology of chimeric and humanized antibodies]. Nihon Rinsho 2002 0.75
252 A case of multiple protruding and flat colorectal tumors analyzed by a cDNA array. Int J Colorectal Dis 2005 0.75
253 [Carcinogenesis in inflammatory bowel disease]. Nihon Rinsho 2012 0.75
254 Preparation and characterization of anti-anti-idiotypic monoclonal antibody ("Ab1-like Ab3") in relation to carcinoembryonic antigen. J Clin Lab Anal 2002 0.75
255 [Expression of trypsin and cancer proliferation in colorectal neoplasms]. Nihon Rinsho 2003 0.75
256 [Epigenetic alterations in cancer]. Tanpakushitsu Kakusan Koso 2006 0.75
257 [An overview of antibody therapy against cancer]. Nihon Rinsho 2012 0.75
258 [Matrix metalloproteinases in human gastrointestinal carcinomas]. Nihon Shokakibyo Gakkai Zasshi 2003 0.75
259 Rapidly growing early gastric cancer with microsatellite instability. J Gastroenterol 2003 0.75
260 [Immunoblastic lymphadenopathy-like T cell lymphoma with high level of serum interleukin-2 and various allergic reactions]. Nihon Rinsho Meneki Gakkai Kaishi 2002 0.75
261 [Effective combination therapy of bortezomib and dexamethasone for two patients with refractory multiple myeloma]. Rinsho Ketsueki 2005 0.75
262 [A case of biliary ascariasis extracted endoscopically]. Nihon Shokakibyo Gakkai Zasshi 2003 0.75
263 [Bortezomib plus dexamethasone treatment followed by reduced-intensity allogeneic stem cell transplantation for multiple myeloma refractory to high-dose chemotherapy with autologous transplantation]. Rinsho Ketsueki 2011 0.75
264 [Collagen diseases with gastrointestinal manifestations]. Nihon Rinsho Meneki Gakkai Kaishi 2004 0.75
265 [Drug therapy of rheumatoid arthritis]. Nihon Rinsho Meneki Gakkai Kaishi 2003 0.75
266 [Thalidomide treatment of patients with refractory myeloma in the institutes participating in the Japan Myeloma Study Group]. Rinsho Ketsueki 2004 0.75
267 [A case of Sjögren's syndrome associated with chronic hepatitis C and sarcoidosis]. Nihon Rinsho Meneki Gakkai Kaishi 2003 0.75
268 [Leukemic meningitis in B-cell prolymphocytic leukemia]. Rinsho Ketsueki 2002 0.75
269 [Case report: primary adenocarcinoma of the thoracic esophagus that probably originated in the esophageal gland]. Nihon Shokakibyo Gakkai Zasshi 2005 0.75
270 [Small intestinal mucin antigen (SIMA)]. Nihon Rinsho 2005 0.75
271 Genetic analysis of advanced colon cancer of 8 mm with liver metastasis. Int J Colorectal Dis 2004 0.75
272 [Long-term survival after autologous peripheral blood stem cell transplantation in a patient with primary AL amyloidosis complicating congestive heart failure]. Rinsho Ketsueki 2007 0.75
273 [Evidence of cartilaginous benefit of treatment with infliximab in rheumatoid arthritis using measurement of serum COMP]. Nihon Rinsho Meneki Gakkai Kaishi 2007 0.75
274 Epigenetics in gastroenterological cancer and prospects for translational research. Nihon Shokakibyo Gakkai Zasshi 2007 0.75
275 [Anti-cancer monoclonal antibody]. Nihon Rinsho 2005 0.75
276 Allelic structures at hypervariable minisatellite B6.7 in Japanese show population specificity. J Hum Genet 2002 0.75
277 [The gastric mucosal injury induced by the immune responses against Helicobacter pylori]. Nihon Rinsho 2002 0.75
278 Evaluation of an mRNA lipofection procedure for human dendritic cells and induction of cytotoxic T lymphocytes against enhanced green fluorescence protein. Tumour Biol 2004 0.75
279 Specific and effective targeting cancer immunotherapy with a combination of three bispecific antibodies. Immunol Lett 2002 0.75
280 A case of ulcerative colitis in which colitic cancer was predictable by a cDNA array analysis. Am J Med 2005 0.75
281 [Nonspecific cross-reacting antigen (NCA)]. Nihon Rinsho 2005 0.75
282 [Dominant negative IGF-I receptor ]. Nihon Rinsho 2003 0.75