Tomio Arai

Author PubWeight™ 105.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Validity, reproducibility, and clinical significance of noninvasive brachial-ankle pulse wave velocity measurement. Hypertens Res 2002 5.91
2 Cardiac rather than intestinal-type background in endoscopic resection specimens of minute Barrett adenocarcinoma. Hum Pathol 2008 3.27
3 Influences of age and gender on results of noninvasive brachial-ankle pulse wave velocity measurement--a survey of 12517 subjects. Atherosclerosis 2003 2.87
4 Telomere lengths are characteristic in each human individual. Exp Gerontol 2002 2.13
5 Brachial-ankle pulse wave velocity as a marker of atherosclerotic vascular damage and cardiovascular risk. Hypertens Res 2003 1.94
6 Accumulation of phosphorylated alpha-synuclein in aging human brain. J Neuropathol Exp Neurol 2003 1.59
7 Lewy body-related alpha-synucleinopathy in aging. J Neuropathol Exp Neurol 2004 1.49
8 Gastric high-grade dysplasia can be associated with submucosal invasion: evaluation of its prevalence in a series of 121 endoscopically resected specimens. Am J Surg Pathol 2014 1.49
9 Ciliated surface in the esophagogastric junction zone: a precursor of Barrett's mucosa or ciliated pseudostratified metaplasia? Am J Surg Pathol 2005 1.42
10 Staging of argyrophilic grains: an age-associated tauopathy. J Neuropathol Exp Neurol 2004 1.23
11 Lewy body pathology involves cutaneous nerves. J Neuropathol Exp Neurol 2008 1.19
12 RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. PLoS One 2009 1.16
13 Incidence and extent of Lewy body-related alpha-synucleinopathy in aging human olfactory bulb. J Neuropathol Exp Neurol 2008 1.15
14 Nomogram of the relation of brachial-ankle pulse wave velocity with blood pressure. Hypertens Res 2003 1.12
15 Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium. J Invest Dermatol 2002 1.11
16 Telomere shortening with aging in the human pancreas. Exp Gerontol 2006 1.10
17 Menopause is an independent factor augmenting the age-related increase in arterial stiffness in the early postmenopausal phase. Atherosclerosis 2006 1.10
18 Is there a set of histologic changes that are invariably reflux associated? Arch Pathol Lab Med 2005 1.04
19 Adenoma, adenocarcinoma and mixed carcinoid-adenocarcinoma arising in a small lesion of the colon. Pathol Int 2003 1.02
20 Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) polymorphisms in cases of lung cancer in Japan. Drug Metab Pharmacokinet 2011 1.00
21 Oncocytic adenocarcinoma of the stomach: parietal cell carcinoma. Am J Surg Pathol 2002 0.99
22 Differences in the definitions used for esophageal and gastric diseases in different countries: endoscopic definition of the esophagogastric junction, the precursor of Barrett's adenocarcinoma, the definition of Barrett's esophagus, and histologic criteria for mucosal adenocarcinoma or high-grade dysplasia. Digestion 2009 0.99
23 Bilateral massive bloody pleurisy complicated by angiosarcoma. Intern Med 2007 0.98
24 Polymorphisms in pro- and anti-inflammatory cytokine genes and susceptibility to atherosclerosis: a pathological study of 1503 consecutive autopsy cases. Hum Mol Genet 2007 0.98
25 Changes of telomere length with aging. Geriatr Gerontol Int 2010 0.98
26 Adenomatoid tumor of the adrenal gland: case report with immunohistochemical study. Pathol Int 2005 0.97
27 Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease. J Neuropathol Exp Neurol 2007 0.97
28 Associations between the CDKN2A/B, ADTRP and PDGFD polymorphisms and the development of coronary atherosclerosis in Japanese patients. J Atheroscler Thromb 2014 0.96
29 Polymorphism of SERPINE2 gene is associated with pulmonary emphysema in consecutive autopsy cases. BMC Med Genet 2010 0.96
30 Increased pulse wave velocity associated with reduced calcaneal quantitative osteo-sono index: possible relationship between atherosclerosis and osteopenia. J Clin Endocrinol Metab 2003 0.94
31 Polymorphisms of the formylpeptide receptor gene (FPR1) and susceptibility to stomach cancer in 1531 consecutive autopsy cases. Biochem Biophys Res Commun 2011 0.93
32 Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older. Exp Gerontol 2007 0.93
33 Developments of geriatric autopsy database and Internet-based database of Japanese single nucleotide polymorphisms for geriatric research (JG-SNP). Mech Ageing Dev 2004 0.92
34 Telomere length variations in 6 mucosal cell types of gastric tissue observed using a novel quantitative fluorescence in situ hybridization method. Hum Pathol 2007 0.91
35 Hepatitis C virus seropositivity, but not hepatitis B virus carrier or seropositivity, associated with increased pulse wave velocity. Atherosclerosis 2003 0.91
36 Aortic pulse wave velocity and the degree of atherosclerosis in the elderly: a pathological study based on 304 autopsy cases. Atherosclerosis 2004 0.90
37 Basal cells have longest telomeres measured by tissue Q-FISH method in lingual epithelium. Exp Gerontol 2008 0.90
38 Cut-off value of the ankle-brachial pressure index at which the accuracy of brachial-ankle pulse wave velocity measurement is diminished. Circ J 2005 0.90
39 Colonic EBV-Associated Lymphoproliferative Disorder in a Patient Treated with Rabbit Antithymocyte Globulin for Aplastic Anemia. Case Rep Gastrointest Med 2012 0.89
40 A replication study examining three common single-nucleotide polymorphisms and the risk of prostate cancer in a Japanese population. Prostate 2010 0.88
41 Telomere shortening in Barrett's mucosa and esophageal adenocarcinoma and its association with loss of heterozygosity. Scand J Gastroenterol 2009 0.88
42 Telomere lengths in the oral epithelia with and without carcinoma. Eur J Cancer 2009 0.88
43 Mitochondrial haplogroups A and M7a confer a genetic risk for coronary atherosclerosis in the Japanese elderly: an autopsy study of 1,536 patients. J Atheroscler Thromb 2010 0.88
44 Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men. BMC Genet 2009 0.87
45 Neuropathologic analysis of Lewy-related α-synucleinopathy in olfactory mucosa. Neuropathology 2012 0.87
46 Neuropathological asymmetry in argyrophilic grain disease. J Neuropathol Exp Neurol 2010 0.87
47 The age-related increase in arterial stiffness is augmented in phases according to the severity of hypertension. Hypertens Res 2004 0.86
48 Amyloid β accumulation assessed with ¹¹C-Pittsburgh compound B PET and postmortem neuropathology. Curr Alzheimer Res 2015 0.86
49 Islands of squamous epithelium and their surrounding mucosa in columnar-lined esophagus: a pathognomonic feature of Barrett's esophagus? Hum Pathol 2005 0.86
50 Is carcinoma in columnar-lined esophagus always located adjacent to intestinal metaplasia?: a histopathologic assessment. Am J Surg Pathol 2015 0.86
51 Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophy. Am J Physiol Heart Circ Physiol 2007 0.85
52 Association between genetic variations in surfactant protein d and emphysema, interstitial pneumonia, and lung cancer in a Japanese population. COPD 2012 0.84
53 β-cell telomere attrition in diabetes: inverse correlation between HbA1c and telomere length. J Clin Endocrinol Metab 2014 0.84
54 Lymphotoxin-alpha polymorphisms and presence of cancer in 1,536 consecutive autopsy cases. BMC Cancer 2008 0.84
55 Accuracy of Death Certificates and Assessment of Factors for Misclassification of Underlying Cause of Death. J Epidemiol 2015 0.84
56 hTERT promoter polymorphism, -1327C>T, is associated with the risk of epithelial cancer. Springerplus 2013 0.84
57 Histological assessment of intra- and inter-institutional reliabilities in detection of desmoplastic reaction in biopsy specimens of early colorectal carcinomas. Pathol Int 2013 0.84
58 Association of telomere shortening in myocardium with heart weight gain and cause of death. Sci Rep 2013 0.84
59 Standard organ weights among elderly Japanese who died in hospital, including 50 centenarians. Pathol Int 2006 0.83
60 Early pathogenesis of cardiac amyloid deposition in senile systemic amyloidosis: close relationship between amyloid deposits and the basement membranes of myocardial cells. Virchows Arch 2003 0.83
61 Hepatocellular telomere length in biliary atresia measured by Q-FISH. World J Surg 2012 0.83
62 Polymorphisms of LTA, LGALS2, and PSMA6 genes and coronary atherosclerosis: a pathological study of 1503 consecutive autopsy cases. Atherosclerosis 2012 0.83
63 Comparative study of monoclonal antibody B72.3 and gross cystic disease fluid protein-15 as markers of apocrine carcinoma of the breast. APMIS 2006 0.83
64 Estrogen-metabolizing enzymes in breast cancers from women over the age of 80 years. J Clin Endocrinol Metab 2005 0.83
65 The Val158Met polymorphism of the catechol-O-methyltransferase gene is associated with the PSA-progression-free survival in prostate cancer patients treated with estramustine phosphate. Eur Urol 2005 0.82
66 Involvement of surfactant protein D in emphysema revealed by genetic association study. Eur J Hum Genet 2011 0.82
67 Alcoholics show reduced telomere length in the oesophagus. J Pathol 2010 0.82
68 Q-FISH analysis of telomere and chromosome instability in the oesophagus with and without squamous cell carcinoma in situ. J Pathol 2010 0.82
69 Estrogen receptor-β gene polymorphism and colorectal cancer risk: effect modified by body mass index and isoflavone intake. Int J Cancer 2012 0.82
70 Undiagnosed cirrhosis occurs frequently in the elderly and requires periodic follow ups and medical treatments. Geriatr Gerontol Int 2008 0.81
71 Maternal grafts protect daughter recipients from acute cellular rejection after pediatric living donor liver transplantation for biliary atresia. Transpl Int 2014 0.81
72 Short telomeres in an oral precancerous lesion: Q-FISH analysis of leukoplakia. J Oral Pathol Med 2011 0.81
73 Association of rs6983561 polymorphism at 8q24 with prostate cancer mortality in a Japanese population. Clin Genitourin Cancer 2011 0.81
74 Detection of human papillomavirus infection of the cervix in very elderly women using PCR. Clin Cancer Res 2005 0.81
75 The relationship between high-sensitive C-reactive protein and pulse wave velocity in healthy Japanese men. Atherosclerosis 2004 0.80
76 Oestrogen receptor-β CA repeat polymorphism is associated with incidence of colorectal cancer among females. Histopathology 2011 0.80
77 Association analysis of single nucleotide polymorphisms in miR-146a and miR-196a2 on the prevalence of cancer in elderly Japanese: a case-control study. Asian Pac J Cancer Prev 2014 0.80
78 Telomere length dynamics in the human pituitary gland: robust preservation throughout adult life to centenarian age. Age (Dordr) 2011 0.80
79 Polymorphism of cytochrome P450 2B6 and prostate cancer risk: a significant association in a Japanese population. Int J Urol 2009 0.80
80 Chromosomal instability and telomere lengths of each chromosomal arm measured by Q-FISH in human fibroblast strains prior to replicative senescence. Mech Ageing Dev 2010 0.80
81 Sustained progression and loss of the gender-related difference in atherosclerosis in the very old: a pathological study of 1074 consecutive autopsy cases. Atherosclerosis 2005 0.80
82 Association of COMT gene polymorphisms with systemic atherosclerosis in elderly Japanese. J Atheroscler Thromb 2012 0.79
83 The normal anatomy around the oesophagogastric junction: a histopathologic view and its correlation with endoscopy. Best Pract Res Clin Gastroenterol 2008 0.79
84 Oestrogen receptor-beta1 but not oestrogen receptor-betacx is of prognostic value in apocrine carcinoma of the breast. APMIS 2008 0.79
85 Association of fucosyltransferase 8 (FUT8) polymorphism Thr267Lys with pulmonary emphysema. J Hum Genet 2011 0.79
86 Cancer and aging: symposium of the 27th annual meeting of the Japanese society for biomedical gerontology, Tokyo. Cancer Immunol Immunother 2004 0.79
87 Smoking confers a MTHFR 677C>T genotype-dependent risk for systemic atherosclerosis: results from a large number of elderly autopsy cases that died in a community-based general geriatric hospital. J Atheroscler Thromb 2009 0.79
88 Chromosome 5q loss in colorectal flat adenomas. Clin Cancer Res 2012 0.79
89 Association of estrogen receptor alpha gene polymorphisms with neurofibrillary tangles. Dement Geriatr Cogn Disord 2004 0.79
90 Palisade vessels as a new histologic marker of esophageal origin in ER specimens from columnar-lined esophagus. Am J Surg Pathol 2011 0.79
91 Association of the chromodomain helicase DNA-binding protein 4 (CHD4) missense variation p.D140E with cancer: potential interaction with smoking. Genes Chromosomes Cancer 2014 0.78
92 Telomere lengths at birth in trisomies 18 and 21 measured by Q-FISH. Gene 2013 0.78
93 The Val158Met polymorphism of the catechol-O-methyltransferase gene is not associated with the risk of sporadic or latent prostate cancer in Japanese men. Int J Urol 2007 0.78
94 Investigation of telomere length dynamics in induced pluripotent stem cells using quantitative fluorescence in situ hybridization. Tissue Cell 2013 0.78
95 Insulin sensitivity and endothelial function in hypertension: a comparison of temocapril and candesartan. Am J Hypertens 2005 0.77
96 Telomere shortening in the esophagus of Japanese alcoholics: relationships with chromoendoscopic findings, ALDH2 and ADH1B genotypes and smoking history. PLoS One 2013 0.77
97 Histopathological diagnosis of adenocarcinoma in Barrett's esophagus. Dig Endosc 2013 0.77
98 Association between estrogen receptor-β dinucleotide repeat polymorphism and incidence of femoral fracture. J Bone Miner Metab 2012 0.77
99 Elderly patients with minimal common carotid atherosclerosis not infrequently have severe coronary atherosclerosis and myocardial infarction. Circ J 2008 0.77
100 Frequent Coamplification of Receptor Tyrosine Kinase and Downstream Signaling Genes in Japanese Primary Gastric Cancer and Conversion in Matched Lymph Node Metastasis. Ann Surg 2016 0.77
101 Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver injury. Shock 2016 0.76
102 Association of the formiminotransferase N-terminal sub-domain containing gene and thrombospondin, type 1, domain-containing 7A gene with the prevalence of vertebral fracture in 2427 consecutive autopsy cases. J Hum Genet 2013 0.76
103 A gene variant in the Atp10d gene associates with atherosclerotic indices in Japanese elderly population. Atherosclerosis 2013 0.76
104 Alternative use of multiple exons 1 of aromatase gene in cancerous and normal breast tissues from women over the age of 80 years. Breast Cancer Res 2009 0.76
105 Thrombomodulin, a novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification. J Mol Cell Cardiol 2012 0.76
106 Genetic Polymorphisms of <i>CYP2A6</i> in a Case-Control Study on Bladder Cancer in Japanese Smokers. Biol Pharm Bull 2016 0.75
107 Systemic Administration of Small Interfering RNA Targeting Human Nestin Inhibits Pancreatic Cancer Cell Proliferation and Metastasis. Pancreas 2016 0.75
108 Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population. BMC Cardiovasc Disord 2014 0.75
109 Chronological trend of calorie intake and the incidence of epithelial neoplasms of the large intestine during the past 30 years in Japan. Oncology 2005 0.75
110 The Prevalence and Clinicopathological Characteristics of High-Grade Pancreatic Intraepithelial Neoplasia: Autopsy Study Evaluating the Entire Pancreatic Parenchyma. Pancreas 2017 0.75
111 Incidence of apoptosis increases with age in colorectal cancer. Exp Gerontol 2002 0.75
112 [Steroid responsive chronic meningoencephalitis reminiscent of rheumatoid meningitis: a case report]. Rinsho Shinkeigaku 2015 0.75
113 In situ detection of apolipoprotein E epsilon 4 in archival human brain. Neuroreport 2004 0.75
114 [Current status of treatment for elderly patients with gastric cancer]. Gan To Kagaku Ryoho 2010 0.75
115 [Diagnosis of effort angina pectoris at rest by first derivative electrocardiography]. J Cardiol 2002 0.75
116 [Current pathological knowledge of Barrett cancer]. Gan To Kagaku Ryoho 2010 0.75
117 Markedly different clinical features in 2 diabetes mellitus patients with extremely high tissue levels of the mitochondrial DNA A3243G mutation. Gerontology 2008 0.75
118 Value of CK14 and CD56 immunostaining in distinguishing small cell carcinoma from squamous cell carcinoma of the esophagus. Nepal Med Coll J 2006 0.75
119 CYP2A13 Genetic Polymorphisms in Relation to the Risk of Bladder Cancer in Japanese Smokers. Biol Pharm Bull 2016 0.75
120 Novel single nucleotide polymorphism of the CYP2A13 gene in Japanese individuals. Drug Metab Pharmacokinet 2011 0.75
121 [Pathologic characteristics of malignant neoplasms occurring in the elderly]. Nihon Rinsho 2015 0.75
122 [A case of pulmonary malignant melanoma mimicking lung abscess]. Nihon Kokyuki Gakkai Zasshi 2011 0.75
123 [Biopsy methods and pathology of Barrett's esophagus]. Nihon Rinsho 2005 0.75
124 [Effects of acute administration of beraprost sodium on parameters related to atherosclerotic vascular damage in coronary artery disease]. J Cardiol 2004 0.75
125 [Analysis of multiple cancers in autopsy cases of elderly hematological malignancies]. Rinsho Ketsueki 2008 0.75
126 [Free/total prostate specific antigen ratio (%PSA) to predict probability of prostate cancer]. Rinsho Byori 2003 0.75
127 TMPRSS2 Met160Val polymorphism: significant association with sporadic prostate cancer, but not with latent prostate cancer in Japanese men. Int J Urol 2014 0.75
128 [Clinicopathologic characteristics of malignant neoplasms occurring in the elderly]. Nihon Ronen Igakkai Zasshi 2010 0.75
129 [Marked decrease of intracranial atherosclerosis in contrast with unchanged coronary artery stenosis in Japan]. Nihon Ronen Igakkai Zasshi 2003 0.75
130 Clinicopathological Features of 15 Occult and 178 Clinical Pancreatic Ductal Adenocarcinomas in 8339 Autopsied Elderly Patients. Pancreas 2016 0.75
131 [Histopathologic diagnosis of Barrett's carcinoma -dysplasia and carcinoma and four unique histologic markers of Barrett's esophagus-]. Nihon Shokakibyo Gakkai Zasshi 2015 0.75