C Malaveille

Author PubWeight™ 73.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study. BMJ 2005 2.22
2 Carcinogen hemoglobin adducts, urinary mutagenicity, and metabolic phenotype in active and passive cigarette smokers. J Natl Cancer Inst 1990 1.78
3 Tissue-mediated mutagenicity of vinylidene chloride and 2-chlorobutadiene in Salmonella typhimurium. Nature 1975 1.66
4 Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis 1996 1.65
5 Ingested mutagens from opium and tobacco pyrolysis products and cancer of the oesophagus. Lancet 1978 1.59
6 DNA repair polymorphisms and cancer risk in non-smokers in a cohort study. Carcinogenesis 2005 1.54
7 Human, rat and mouse liver-mediated mutagenicity of vinyl chloride in S. typhimurium strains. Int J Cancer 1975 1.53
8 Liver-microsome-mediated formation of alkylating agents from vinyl bromide and vinyl chloride. Biochem Biophys Res Commun 1975 1.52
9 DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case-control study. Int J Cancer 2001 1.48
10 Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100. Biochem Biophys Res Commun 1975 1.39
11 Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens. Nature 1994 1.31
12 Mutagenicity of vinyl chloride, chloroethyleneoxide, chloroacetaldehyde and chloroethanol. Biochem Biophys Res Commun 1975 1.23
13 Mutagens produced by the pyrolysis of opium and its alkaloids as possible risk factors in cancer of the bladder and oesophagus. Carcinogenesis 1982 1.21
14 Detection of carcinogen-DNA adducts in exfoliated urothelial cells of cigarette smokers: association with smoking, hemoglobin adducts, and urinary mutagenicity. Cancer Epidemiol Biomarkers Prev 1993 1.17
15 Genetic polymorphism of N-acetyltransferases, glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase in relation to malignant and benign pancreatic disease risk. The International Pancreatic Disease Study Group. Eur J Cancer Prev 1998 1.15
16 Characterization and identification of 6 mutagens in opium pyrolysates implicated in oesophageal cancer in Iran. Mutat Res 1985 1.11
17 Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases. Arch Toxicol 1979 1.10
18 Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers. Ann Oncol 2007 1.05
19 Combined effect of polymorphic GST genes on individual susceptibility to lung cancer. Int J Cancer 1998 1.04
20 DNA adducts in urothelial cells: relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smoke. Int J Cancer 1996 1.02
21 In vitro metabolism and microsome-mediated mutagenicity of dialkylnitrosamines in rat, hamster, and mouse tissues. Cancer Res 1975 1.02
22 Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions. Carcinogenesis 2006 1.01
23 Levels of direct-acting mutagens, total N-nitroso compounds in nitrosated fermented fish products, consumed in a high-risk area for gastric cancer in southern China. Mutat Res 1992 1.01
24 High microsome-mediated mutagenicity of the 3,4-dihydrodiol of 7-methylbenz[a]anthracene in S. typhimurium TA 98. Biochem Biophys Res Commun 1977 1.00
25 Quantitative analysis of DNA methylation after whole bisulfitome amplification of a minute amount of DNA from body fluids. Epigenetics 2009 1.00
26 Epstein-Barr virus activation in Raji cells by extracts of preserved food from high risk areas for nasopharyngeal carcinoma. Carcinogenesis 1988 0.99
27 Black (air-cured) and blond (flue-cured) tobacco cancer risk. IV: Molecular dosimetry studies implicate aromatic amines as bladder carcinogens. Eur J Cancer 1993 0.98
28 Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems. Mutat Res 1980 0.98
29 White blood cell DNA adducts and fruit and vegetable consumption in bladder cancer. Carcinogenesis 2000 0.98
30 Inducible nitric oxide synthase, anti-oxidant enzymes and Helicobacter pylori infection in gastritis and gastric precancerous lesions in humans. Eur J Cancer Prev 1998 0.96
31 Carcinogenic nitrosamines: free radical aspects of their action. Free Radic Biol Med 1989 0.96
32 Carcinogenicity of chloroethylene oxide, an ultimate reactive metabolite of vinyl chloride, and bis(chloromethyl)ether after subcutaneous administration and in initiation-promotion experiments in mice. Cancer Res 1980 0.95
33 Comparative mutagenicity of N-nitrosamines in a semi-solid and in a liquid incubation system in the presence of rat or human tissue fractions. Mutat Res 1976 0.94
34 Quantitative comparison of carcinogenicity, mutagenicity and electrophilicity of 10 direct-acting alkylating agents and of the initial O6:7-alkylguanine ratio in DNA with carcinogenic potency in rodents. Mutat Res 1983 0.93
35 Mutagenicity of isomeric diol-epoxides of benzo[a]pyrene and benz[a]anthracene in S. typhimurium TA98 and TA100 and in V79 Chinese hamster cells. Mutat Res 1977 0.91
36 Volatile nitrosamine levels and genotoxicity of food samples from high-risk areas for nasopharyngeal carcinoma before and after nitrosation. Int J Cancer 1989 0.91
37 White blood cell DNA adducts, smoking, and NAT2 and GSTM1 genotypes in bladder cancer: a case-control study. Cancer Epidemiol Biomarkers Prev 1998 0.88
38 Immunohistochemical detection of pulmonary cytochrome P450IA and metabolic activities associated with P450IA1 and P450IA2 isozymes in lung cancer patients. Environ Health Perspect 1992 0.88
39 Analysis of 4-aminobiphenyl-DNA adducts in human urinary bladder and lung by alkaline hydrolysis and negative ion gas chromatography-mass spectrometry. Environ Health Perspect 1994 0.87
40 Prevalence of genotoxic chemicals among animal and human carcinogens evaluated in the IARC Monograph Series. Cell Biol Toxicol 1989 0.86
41 32P Postlabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) as a major DNA-damaging agent. Carcinogenesis 1991 0.86
42 Methodology of laboratory measurements in prospective studies on gene-environment interactions: the experience of GenAir. Mutat Res 2005 0.85
43 32P-postlabelling analysis of DNA adducted with urinary mutagens from smokers of black tobacco. Carcinogenesis 1990 0.85
44 Some factors determining the concentration of liver proteins for optimal mutagenicity of chemicals in the Salmonella/microsome assay. Mutat Res 1979 0.84
45 Transplacental carcinogenic effect of 3-methylcholanthrene in mice and its quantitation in fetal tissues. J Natl Cancer Inst 1971 0.84
46 Meat intake and bladder cancer in a prospective study: a role for heterocyclic aromatic amines? Cancer Causes Control 2008 0.84
47 Metabolic polymorphism affecting DNA binding and excretion of carcinogens in humans. Pharmacogenetics 1995 0.84
48 Substituted hydroxyphenanthrenes in opium pyrolysates implicated in oesophageal cancer in Iran: structures and in vitro metabolic activation of a novel class of mutagens. Carcinogenesis 1987 0.83
49 Critical importance of microsome concentration in mutagenesis assay with V79 Chinese hamster cells. Mutat Res 1979 0.81
50 In vivo nitrosoproline formation and other risk factors in Costa Rican children from high- and low-risk areas for gastric cancer. Cancer Epidemiol Biomarkers Prev 1994 0.81
51 Cytochrome P4501A2: enzyme induction and genetic control in determining 4-aminobiphenyl-hemoglobin adduct levels. Cancer Epidemiol Biomarkers Prev 1996 0.81
52 Hydroxylation and nitroreduction are required to activate dimethylnitramine into alkylating and mutagenic agents. Carcinogenesis 1983 0.81
53 Mutagens, N-nitroso compounds and their precursors in gastric juice from patients with and without precancerous lesions of the stomach. Eur J Cancer 1993 0.81
54 Microsome-mediated mutagenicities of the dihydrodiols of 7,12-dimethylbenz[a]anthracene: high mutagenic activity of the 3,4-dihydrodiol. Biochem Biophys Res Commun 1978 0.80
55 Mutagenicity and metabolism of vinyl chloride and related compounds. Environ Health Perspect 1976 0.80
56 DNA adduct formation and 7-ethoxyresorufin O-deethylase induction in primary culture of rainbow trout hepatocytes exposed to benzo[a]pyrene. Toxicol In Vitro 1992 0.80
57 Impact of polymorphisms in xeno(endo)biotic metabolism on pattern and frequency of p53 mutations in bladder cancer. Mutat Res 2000 0.79
58 Factors for efficiency of the Salmonella/microsome mutagenicity assay. Chem Biol Interact 1977 0.79
59 Interstrain comparison of hepatic and renal microsomal carcinogen metabolism and liver S9-mediated mutagenicity in DA and Lewis rats phenotyped as poor and extensive metabolizers of debrisoquine. Drug Metab Dispos 1986 0.79
60 Comparison of the hydroxylation of benzo(a)pyrene with the metabolism of vinyl chloride, N-nitrosomorpholine, and N-nitroso-N'-methylpiperazine to mutagens by human and rat liver microsomal fractions. Cancer Res 1980 0.78
61 Interrelationships in mice of antipyrine half-life, hepatic monooxygenase activities and liver S9-mediated mutagenicity of aflatoxin B1, benzo[alpha]pyrene 7,8-dihydrodiol, 2-acetylaminofluorene and N-nitrosomorpholine. Chem Biol Interact 1983 0.78
62 Epstein-Barr virus activators, mutagens and volatile nitrosamines in preserved food samples from high-risk areas for nasopharyngeal carcinoma. IARC Sci Publ 1991 0.78
63 Intragastric mutagens and lowered anti-oxidant defence as risk factors for gastric cancer. Eur J Cancer Prev 1993 0.78
64 DNA adduct detection: some applications in monitoring exposure to environmental genotoxic chemicals. IARC Sci Publ 1993 0.77
65 4-Aminobiphenyl-DNA adducts and p53 mutations in bladder cancer. Int J Cancer 1998 0.77
66 Urinary excretion of S-benzylmercapturic acid as an indicator of N-nitroso-N-methylbenzylamine exposure. Cancer Lett 1991 0.77
67 The choice of controls in a case-control study on WBC-DNA adducts and metabolic polymorphisms. Biomarkers 2000 0.77
68 Detection of aflatoxins and related metabolites by radioimmunoassay. J Natl Cancer Inst 1982 0.77
69 Interaction between genetic polymorphism of cytochrome P450-1B1 and environmental pollutants in breast cancer risk. Eur J Cancer Prev 2004 0.77
70 Bacterial and mammalian mutagenicity tests: validation and comparative studies on 180 chemicals. IARC Sci Publ 1980 0.76
71 Exposure to N-nitrosamines and other risk factors for gastric cancer in Costa Rican children. IARC Sci Publ 1991 0.76
72 The association of bacterial mutagenicity of hydrocarbon-derived 'bay-region' dihydrodiols with the Iball indices for carcinogenicity and with the extents of DNA-binding on mouse skin of the parent hydrocarbons. Chem Biol Interact 1979 0.76
73 Formation of direct-acting genotoxic substances in nitrosated smoked fish and meat products: identification of simple phenolic precursors and phenyldiazonium ions as reactive products. Food Chem Toxicol 1989 0.76
74 Inhibition by specific antibodies of the mutagenicity of aflatoxin B1 in bacteria. Oncodev Biol Med 1982 0.76
75 Some aspects of metabolic activation of chemical carcinogens in relation to their organ specificity. Arch Toxicol 1977 0.75
76 Subcellular metabolic activation systems: their utility and limitations in predicting organ and species specific carcinogenesis of chemicals. Basic Life Sci 1983 0.75
77 Synthesis, structure-activity relationships and a reaction mechanism for mutagenic N-nitroso derivatives of glycosylamines and Amadori compounds--model substances for N-nitrosated early Maillard reaction products. Food Chem Toxicol 1987 0.75
78 Synthesis, analysis and mutagenic activity of N-nitroso derivatives of glycosylamines and Amadori compounds: nitrosated model substances for the early Maillard reaction products. IARC Sci Publ 1987 0.75
79 Carcinogen-metabolizing enzymes and susceptibility to chemical carcinogenesis. IARC Sci Publ 1983 0.75
80 Monoclonal antibody-directed analysis of cytochrome P-450-dependent monooxygenases and mutagen activation in the livers of DBA/2 and C57BL/6 mice. Cancer Res 1986 0.75
81 Contribution of DNA methylation and benzylation to N-nitroso-N-benzyl-methylamine-induced mutagenesis in bacteria: effects of rat liver cytochrome P450 isozymes and glutathione transferases. Carcinogenesis 1990 0.75
82 Rat and mouse tissue-mediated mutagenicity of ring-substituted 3,3-dimethyl-1-phenyltriazenes in Salmonella typhimurium. Mutat Res 1976 0.75
83 Effect of glutathione and uridine 5'-diphosphoglucuronic acid on benzo(a)pyrene mutagenesis in the Salmonella/microsome assay. Dev Toxicol Environ Sci 1980 0.75
84 Absence of mutagenicity of praziquantel, a new, effective, anti-schistosomal drug, in bacteria, yeasts, insects and mammalian cells. Mutat Res 1978 0.75
85 Quantification of the genotoxic effects of alkylating agents in bacterial assays. Mutagenesis 1988 0.75
86 High mutagenicity of N-(alpha-acyloxy)alkyl-N-alkylnitrosamines in S. typhimurium: model compounds for metabolically activated N,N-dialkylnitrosamines. Mutat Res 1978 0.75
87 Short-term assays to predict carcinogenicity. Short-term assays for the analysis of body fluids and excreta. IARC Sci Publ 1986 0.75
88 Differential effect of phenobarbitone, pregnenolone-16-a-carbonitrile and adinoacetonitrile on dialkylnitrosamine metabolism and mutagenicity in vitro. Chem Biol Interact 1975 0.75
89 Possible involvement of a vicinal, non-bay-region dihydrodiol-epoxide in the activation of dibenzo[a,e]fluoranthene into bacterial mutagens. Carcinogenesis 1984 0.75
90 [Genotoxicity of carcinogenic substances in humans and animals]. J Toxicol Clin Exp 1989 0.75
91 Mutagenicity studies in Salmonella typhimurium on some carcinogenic N-nitramines in vitro and in the host-mediated assay in rats. Cancer Res 1981 0.75
92 Mutagenicity and carcinogenicity of environmental chemicals. Regul Toxicol Pharmacol 1982 0.75
93 Proceedings: Comparative mutagenicity studies with S. typhimurium of dimethylnitrosamine (DMN) and diethylnitrosamine (DEN), after metabolic activation with liver and lung microsomes. Mutat Res 1975 0.75
94 Basic requirements for in vitro metabolic activation systems in mutagenesis testing. IARC Monogr Eval Carcinog Risk Chem Hum Suppl 1980 0.75
95 Short-term assays to predict carcinogenicity. Short-term assays using bacteria. IARC Sci Publ 1986 0.75
96 Comparative electrophilicity, mutagenicity, DNA repair induction activity, and carcinogenicity of some N- and O-acyl derivatives of N-hydroxy-2-aminoflourene. Cancer Res 1977 0.75
97 [Distribution of (14C)MCA and its derivatives in mouse tissues (author's transl)]. Chem Biol Interact 1973 0.75
98 Short-term assays to predict carcinogenicity. DNA damage and repair. IARC Sci Publ 1986 0.75
99 Studies on the efficiency of the Salmonella/rat hepatocyte assay for the detection of carcinogens as mutagens: activation of 1,2-dimethyl-hydrazine and procarbazine into bacterial mutagens. Carcinogenesis 1983 0.75
100 Destruction of aromatic amines in laboratory wastes through oxidation with potassium permanganate/sulfuric acid into non-mutagenic derivatives. Am Ind Hyg Assoc J 1985 0.75
101 N-nitroso compounds, genotoxins and their precursors in gastric juice from humans with and without precancerous lesions of the stomach. IARC Sci Publ 1991 0.75
102 Identification, occurrence and mutagenicity in Salmonella typhimurium of two synthetic nitroarenes, musk ambrette and musk xylene, in Indian chewing tobacco and betel quid. Food Chem Toxicol 1986 0.75
103 [Metabolic activation and the mutagenic properties of carcinogenic N-nitramines in a liquid incubation test]. Vopr Onkol 1981 0.75
104 Lack of mutagenicity of synthetic pyrethroids in Salmonella typhimurium strains and in V79 Chinese hamster cells. Mutat Res 1984 0.75
105 Effect of glutathione and uridine 5'-diphosphoglucuronic acid on mutagenesis by benzo[a]pyrene and aflatoxin B1 in the Salmonella/microsome assay. Mutat Res 1981 0.75
106 Metabolic and mutagenicity studies on DDT and 15 derivatives. Detection of 1,1-bis(p-chlorophenyl)-2,2-dichloroethane and 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethyl acetate (kelthane acetate) as mutagens in Salmonella typhimurium and of 1,1-bis(p-chlorophenyl) ethylene oxide, a likely metabolite, as an alkylating agent. Chem Biol Interact 1979 0.75
107 Mutagenic and alkylating activities of 3-methyl-1-phenyltriazenes and their possible role as carcinogenic metabolites of the parent dimethyl compounds. Cancer Res 1982 0.75
108 Carcinogen-metabolizing enzymes and susceptibility to chemical carcinogenesis. IARC Sci Publ 1982 0.75
109 Mutagenicity of benzo[a]pyrene 7,8-dihydrodiol and 7,12-dimethylbenz[a]anthracene 3,4-dihydrodiol in S. typhimurium mediated by microsomes from rat liver and mouse skin. Chem Biol Interact 1980 0.75
110 [The relation between carcinogenesis and mutagenesis: a re-evaluation]. Bull Acad Natl Med 1989 0.75
111 [In vivo and in vitro studies of mutagenic properties of carcinogenic N-nitramines]. Vopr Onkol 1981 0.75
112 Short-term assays to predict carcinogenicity. Metabolic activation. IARC Sci Publ 1986 0.75
113 Metabolic activation of 3-methylcholanthrene: mutagenic and transforming activities of the 9,10-dihydrodiol. Biochem Biophys Res Commun 1978 0.75
114 Quantitative comparisons between carcinogenicity, mutagenicity and electrophilicity of direct-acting N-nitroso compounds and other alkylating agents. IARC Sci Publ 1982 0.75
115 Short-term tests and mycotoxins. Ann Nutr Aliment 1977 0.75
116 Mutagenicity of beta-oxidized N,N,-di-n-propylnitrosamine derivatives in S. typhimurium mediated by rat and hamster tissues. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol 1976 0.75
117 Destruction of carcinogenic and mutagenic N-nitrosamides in laboratory wastes. IARC Sci Publ 1984 0.75
118 Preparation of aflatoxin B1-BSA conjugate with high hapten/carrier molar ratio. J Immunol Methods 1983 0.75
119 Short-term assays to predict carcinogenicity. The host-mediated assay. IARC Sci Publ 1986 0.75
120 Screening assays for carcinogenic agents and mixtures: an appraisal based on data in the IARC Monograph series. IARC Sci Publ 1990 0.75