|
1
|
SOCS3 negatively regulates IL-6 signaling in vivo.
|
Nat Immunol
|
2003
|
4.90
|
|
2
|
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells.
|
Nat Immunol
|
2008
|
3.07
|
|
3
|
ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity.
|
Nucleic Acids Res
|
2011
|
2.23
|
|
4
|
Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling.
|
Proc Natl Acad Sci U S A
|
2004
|
1.81
|
|
5
|
SOCS2 negatively regulates growth hormone action in vitro and in vivo.
|
J Clin Invest
|
2005
|
1.66
|
|
6
|
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.
|
Mol Cell
|
2006
|
1.41
|
|
7
|
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.
|
Blood
|
2007
|
1.30
|
|
8
|
ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification.
|
Genes Dev
|
2011
|
1.30
|
|
9
|
Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.
|
J Biol Chem
|
2002
|
1.26
|
|
10
|
Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells.
|
Stem Cells
|
2005
|
1.22
|
|
11
|
The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.
|
Nat Struct Mol Biol
|
2005
|
1.18
|
|
12
|
The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.
|
J Cell Biol
|
2010
|
1.14
|
|
13
|
The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo.
|
Blood
|
2007
|
1.13
|
|
14
|
Regulation of hematopoietic stem cells by their mature progeny.
|
Proc Natl Acad Sci U S A
|
2010
|
1.09
|
|
15
|
Development of hydrocephalus in mice lacking SOCS7.
|
Proc Natl Acad Sci U S A
|
2004
|
1.07
|
|
16
|
Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradation.
|
J Biol Chem
|
2006
|
1.05
|
|
17
|
SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
|
J Mol Biol
|
2009
|
1.04
|
|
18
|
Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling.
|
Proc Natl Acad Sci U S A
|
2005
|
1.00
|
|
19
|
Transcriptional regulation of the homeobox gene Mixl1 by TGF-beta and FoxH1.
|
Biochem Biophys Res Commun
|
2005
|
0.98
|
|
20
|
Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.
|
PLoS One
|
2013
|
0.85
|
|
21
|
Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
|
Proc Natl Acad Sci U S A
|
2010
|
0.84
|
|
22
|
Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia.
|
Growth Factors
|
2014
|
0.79
|
|
23
|
SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo.
|
J Immunol
|
2009
|
0.78
|
|
24
|
Correction for Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.
|
Proc Natl Acad Sci U S A
|
2015
|
0.75
|