Published in Toxicology on March 15, 2005
A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. J Cell Sci (2006) 1.20
Low oxygen levels induce the expression of the embryonic morphogen Nodal. Mol Biol Cell (2011) 0.85
Dissection of a hypoxia-induced, nitric oxide-mediated signaling cascade. Mol Biol Cell (2009) 0.82
Increased endogenous nitric oxide release by iron chelation and purinergic activation in the rat carotid body. Open Biochem J (2007) 0.79
Planning cancer control in Latin America and the Caribbean. Lancet Oncol (2013) 8.43
Economic burden of cancer across the European Union: a population-based cost analysis. Lancet Oncol (2013) 3.95
The human tissue bill. BMJ (2004) 2.57
Hypoxia-driven selection of the metastatic phenotype. Cancer Metastasis Rev (2007) 2.52
The influence of light at night exposure on melatonin levels among Canadian rotating shift nurses. Cancer Epidemiol Biomarkers Prev (2011) 2.27
Dietary vitamin K and therapeutic warfarin alter the susceptibility to vascular calcification in experimental chronic kidney disease. Kidney Int (2013) 1.67
A catalyst for change: the European cancer Patient's Bill of Rights. Oncologist (2014) 1.55
Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity. Mol Cancer Ther (2008) 1.53
The state of research and development in global cancer surgery. Ann Surg (2012) 1.46
A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells. Cancer Res (2013) 1.46
Perinatal iron deficiency combined with a high-fat diet causes obesity and cardiovascular dysregulation. Endocrinology (2011) 1.43
Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration. J Cell Biochem (2008) 1.41
Endometrial decidualization does not trigger the blood pressure decline of normal early pregnancy in mice. Biol Reprod (2012) 1.41
Persistent lowering of arterial pressure after continuous and intermittent therapy. J Hypertens (2003) 1.40
Adjuvant chemotherapy for non-small cell lung cancer: a New Zealand perspective. N Z Med J (2006) 1.38
Use of quantum dot luminescent probes to achieve single-cell resolution of human oral bacteria in biofilms. Appl Environ Microbiol (2006) 1.36
Intervertebral disc degeneration can lead to "stress-shielding" of the anterior vertebral body: a cause of osteoporotic vertebral fracture? Spine (Phila Pa 1976) (2004) 1.34
European Clinical Trials Directive: responses made to MHRA consultation letter MLX 287. Lancet (2003) 1.33
Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800mg/m(2) combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer. Lung Cancer (2009) 1.21
Vertebroplasty: only small cement volumes are required to normalize stress distributions on the vertebral bodies. Spine (Phila Pa 1976) (2009) 1.19
Discogenic origins of spinal instability. Spine (Phila Pa 1976) (2005) 1.19
Nanomechanical properties of glucans and associated cell-surface adhesion of Streptococcus mutans probed by atomic force microscopy under in situ conditions. Microbiology (2007) 1.17
Spontaneous pregnancy loss mediated by abnormal maternal inflammation in rats is linked to deficient uteroplacental perfusion. J Immunol (2010) 1.15
Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia. J Exp Med (2014) 1.09
Non-disruptive, real-time analyses of the metabolic status and viability of Streptococcus mutans cells in response to antimicrobial treatments. J Microbiol Methods (2004) 1.09
Mechanical efficacy of vertebroplasty: influence of cement type, BMD, fracture severity, and disc degeneration. Bone (2007) 1.09
Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway. J Biol Chem (2002) 1.08
Uterine NK cells, spiral artery modification and the regulation of blood pressure during mouse pregnancy. Am J Reprod Immunol (2010) 1.08
Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide. Cancer Res (2011) 1.07
Confluence-dependent resistance to doxorubicin in human MDA-MB-231 breast carcinoma cells requires hypoxia-inducible factor-1 activity. Exp Cell Res (2006) 1.07
Spiral arterial remodeling is not essential for normal blood pressure regulation in pregnant mice. Hypertension (2010) 1.06
Trends in the global funding and activity of cancer research. Mol Oncol (2008) 1.06
Cardiovascular aspects of sexual medicine. J Sex Med (2010) 1.06
Role of EG-VEGF in human placentation: Physiological and pathological implications. J Cell Mol Med (2009) 1.05
Activated macrophages inhibit human cytotrophoblast invasiveness in vitro. Biol Reprod (2005) 1.05
Critical appraisal of translational research models for suitability in performance assessment of cancer centers. Oncologist (2012) 1.04
mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3. Exp Cell Res (2009) 1.04
The interaction between endothelin-1 and nitric oxide in the vasculature: new perspectives. Am J Physiol Regul Integr Comp Physiol (2011) 1.04
Priapism. Can J Psychiatry (2004) 1.04
Lung cancer susceptibility model based on age, family history and genetic variants. PLoS One (2009) 1.03
A framework for discussion on how to improve prevention, management, and control of hypertension in Canada. Can J Cardiol (2012) 1.03
The role of macrophages in utero-placental interactions during normal and pathological pregnancy. Immunol Invest (2008) 1.02
The internal mechanical properties of cervical intervertebral discs as revealed by stress profilometry. Eur Spine J (2007) 1.01
Annulus fissures are mechanically and chemically conducive to the ingrowth of nerves and blood vessels. Spine (Phila Pa 1976) (2012) 1.00
Understanding the impact of public policy on cancer research: a bibliometric approach. Eur J Cancer (2010) 0.99
Carbon monoxide inhibits hypoxia/reoxygenation-induced apoptosis and secondary necrosis in syncytiotrophoblast. Am J Pathol (2006) 0.98
Chemosensitization of cancer by nitric oxide. Curr Pharm Des (2008) 0.98
Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide. Cancer Res (2008) 0.98
Vascular calcification in animal models of CKD: A review. Am J Nephrol (2010) 0.98
Bone creep can cause progressive vertebral deformity. Bone (2009) 0.97
Comparison of buprenorphine and meloxicam for postsurgical analgesia in rats: effects on body weight, locomotor activity, and hemodynamic parameters. J Am Assoc Lab Anim Sci (2010) 0.95
Online information as a decision making aid for cancer patients: recommendations from the Eurocancercoms project. Eur J Cancer (2011) 0.95
Time-dependent compressive deformation of the ageing spine: relevance to spinal stenosis. Spine (Phila Pa 1976) (2010) 0.95
Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice. Prostaglandins Other Lipid Mediat (2007) 0.95
Coordinated regulation of human trophoblast invasiveness by macrophages and interleukin 10. Biol Reprod (2006) 0.95
Hypoxia induced resistance to doxorubicin in prostate cancer cells is inhibited by low concentrations of glyceryl trinitrate. J Urol (2003) 0.94
Throwing a wrench in the works? Lancet Oncol (2003) 0.94
Chemosensitization of cancer in vitro and in vivo by nitric oxide signaling. Clin Cancer Res (2007) 0.94
Swelling of articular cartilage depends on the integrity of adjacent cartilage and bone. Biorheology (2008) 0.93
Vertebroplasty and Kyphoplasty Can Restore Normal Spine Mechanics following Osteoporotic Vertebral Fracture. J Osteoporos (2010) 0.93
When are intervertebral discs stronger than their adjacent vertebrae? Spine (Phila Pa 1976) (2007) 0.93
In situ and non-invasive detection of specific bacterial species in oral biofilms using fluorescently labeled monoclonal antibodies. J Microbiol Methods (2005) 0.93
Outer annulus tears have less effect than endplate fracture on stress distributions inside intervertebral discs: relevance to disc degeneration. Clin Biomech (Bristol, Avon) (2006) 0.93
Beneficial impact of exercise and obesity interventions on erectile function and its risk factors. J Sex Med (2009) 0.93
Phase II study of nitric oxide donor for men with increasing prostate-specific antigen level after surgery or radiotherapy for prostate cancer. Urology (2009) 0.93
Identification of the primary outcomes that result from deficient spiral arterial modification in pregnant mice. Pregnancy Hypertens (2011) 0.92
Propagation of surface fissures in articular cartilage in response to cyclic loading in vitro. Clin Biomech (Bristol, Avon) (2003) 0.92
Is activation of the back muscles impaired by creep or muscle fatigue? Spine (Phila Pa 1976) (2010) 0.91
Inhibition of breast carcinoma and trophoblast cell invasiveness by vascular endothelial growth factor. Exp Cell Res (2003) 0.91
Mechanical function of vertebral body osteophytes, as revealed by experiments on cadaveric spines. Spine (Phila Pa 1976) (2011) 0.90
Hypoxia prevents etoposide-induced DNA damage in cancer cells through a mechanism involving hypoxia-inducible factor 1. Mol Cancer Ther (2009) 0.90
Strength of the cervical spine in compression and bending. Spine (Phila Pa 1976) (2007) 0.90
Smoking and other lifestyle factors in relation to erectile dysfunction. BJU Int (2005) 0.90
Contractile properties of human placental anchoring villi. Am J Physiol Regul Integr Comp Physiol (2004) 0.90
Significance of cartilage endplate within herniated disc tissue. Eur Spine J (2014) 0.89
Heme oxygenase activity in placenta: direct dependence on oxygen availability. Am J Physiol Heart Circ Physiol (2002) 0.89
ISSLS Prize winner: Mechanical influences in progressive intervertebral disc degeneration. Spine (Phila Pa 1976) (2014) 0.89
Light intensity exposure, sleep duration, physical activity, and biomarkers of melatonin among rotating shift nurses. Chronobiol Int (2009) 0.88
Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells. Biochem Biophys Res Commun (2002) 0.88
Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease. Int J Mol Sci (2013) 0.88
Alterations in maternal and fetal heart functions accompany failed spiral arterial remodeling in pregnant mice. Am J Obstet Gynecol (2011) 0.86
Evaluation of bacteria-induced enamel demineralization using optical profilometry. Dent Mater (2009) 0.86
A survey of public funding of cancer research in the European union. PLoS Med (2006) 0.86
Morphological and functional evidence for the contribution of the pudendal artery in aging-induced erectile dysfunction. J Sex Med (2010) 0.85
Noncatalytic domain of uPA stimulates human extravillous trophoblast migration by using phospholipase C, phosphatidylinositol 3-kinase and mitogen-activated protein kinase. Exp Cell Res (2003) 0.84
Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression. Exp Cell Res (2010) 0.84
Nitric oxide-mediated regulation of hypoxia-induced B16F10 melanoma metastasis. Int J Cancer (2004) 0.84
FGF-23 is associated with cardiac troponin T and mortality in hemodialysis patients. Hemodial Int (2012) 0.84
Safety profile of a new liquid whitening gel. Compend Contin Educ Dent (2002) 0.84
Cancer control in Bangladesh. Jpn J Clin Oncol (2013) 0.83
Cardiovascular adaptations of pregnancy in T and B cell-deficient mice. Biol Reprod (2011) 0.83