Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.

PubWeight™: 0.80‹?›

🔗 View Article (PMID 15691664)

Published in Nucl Med Biol on January 01, 2005

Authors

Nachwa Jarkas1, Jonathan McConathy, John R Votaw, Ronald J Voll, Eugene Malveaux, Vernon M Camp, Larry Williams, Robin R Goodman, Clinton D Kilts, Mark M Goodman

Author Affiliations

1: Department of Radiology, Division of Radiological Sciences, Emory University, Atlanta, GA 30322, USA.

Articles by these authors

Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab (2007) 11.79

Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma. J Nucl Med (2007) 2.83

Silencing of CXCR4 blocks breast cancer metastasis. Cancer Res (2005) 2.59

Post-traumatic stress disorder and incidence of coronary heart disease: a twin study. J Am Coll Cardiol (2013) 2.03

AAPM Task Group 108: PET and PET/CT shielding requirements. Med Phys (2006) 1.94

Ecstasy and agony: activation of the human amygdala in positive and negative emotion. Psychol Sci (2002) 1.89

The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density. BMC Genet (2005) 1.70

A comparison of resting-state brain activity in humans and chimpanzees. Proc Natl Acad Sci U S A (2007) 1.65

(18)F-FECNT: validation as PET dopamine transporter ligand in parkinsonism. Exp Neurol (2010) 1.61

Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys. Brain (2011) 1.55

Assessment and treatment of elopement: a replication and extension. J Appl Behav Anal (2003) 1.49

Dopaminergic mechanisms of reduced basal ganglia responses to hedonic reward during interferon alfa administration. Arch Gen Psychiatry (2012) 1.48

Face processing in the chimpanzee brain. Curr Biol (2008) 1.47

CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models. Cancer Res (2007) 1.38

Effects of combined dopamine and serotonin transporter inhibitors on cocaine self-administration in rhesus monkeys. J Pharmacol Exp Ther (2006) 1.34

Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain. J Neurosci (2012) 1.31

Detection of recurrent prostate carcinoma with anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT. Radiology (2011) 1.30

A preliminary study of anti-1-amino-3-18F-fluorocyclobutyl-1-carboxylic acid for the detection of prostate cancer. J Nucl Med (2007) 1.29

MR∕PET quantification tools: registration, segmentation, classification, and MR-based attenuation correction. Med Phys (2012) 1.28

Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging. J Pharmacol Exp Ther (2004) 1.24

Characterization of primary prostate carcinoma by anti-1-amino-2-[(18)F] -fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F] FACBC) uptake. Am J Nucl Med Mol Imaging (2013) 1.21

Development of a unique small molecule modulator of CXCR4. PLoS One (2012) 1.18

Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys. Pharmacol Biochem Behav (2008) 1.17

Brain blood-flow alterations induced by therapeutic vagus nerve stimulation in partial epilepsy: II. prolonged effects at high and low levels of stimulation. Epilepsia (2004) 1.14

Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNT. J Nucl Med (2003) 1.13

Effect of methylphenidate on executive functioning in adults with attention-deficit/hyperactivity disorder: normalization of behavior but not related brain activity. Biol Psychiatry (2004) 1.13

First evaluation of a 99mTc-tricarbonyl complex, 99mTc(CO)3(LAN), as a new renal radiopharmaceutical in humans. J Nucl Med (2006) 1.12

Improved synthesis of anti-[18F]FACBC: improved preparation of labeling precursor and automated radiosynthesis. Appl Radiat Isot (2003) 1.11

Biodistribution and radiation dosimetry of the synthetic nonmetabolized amino acid analogue anti-18F-FACBC in humans. J Nucl Med (2007) 1.11

99mTc-MAEC complexes: new renal radiopharmaceuticals combining characteristics of (99m)Tc-MAG3 and (99m)Tc-EC. J Nucl Med (2004) 1.09

Modeling the spatial and temporal dependence in FMRI data. Biometrics (2010) 1.08

Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial. Trials (2012) 1.06

MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing radiation. Pharm Res (2012) 1.05

Altered functional connectivity of the insular cortex across prefrontal networks in cocaine addiction. Psychiatry Res (2013) 1.04

Minimizing artifacts resulting from respiratory and cardiac motion by optimization of the transmission scan in cardiac PET/CT. Med Phys (2007) 1.04

Donepezil HCl (E2020) maintains functional brain activity in patients with Alzheimer disease: results of a 24-week, double-blind, placebo-controlled study. Am J Geriatr Psychiatry (2003) 1.04

Radiohalogenated nonnatural amino acids as PET and SPECT tumor imaging agents. Med Res Rev (2011) 1.03

Cocaine-induced brain activation determined by positron emission tomography neuroimaging in conscious rhesus monkeys. Psychopharmacology (Berl) (2001) 1.03

Task-specific recruitment of dorsal and ventral visual areas during tactile perception. Neuropsychologia (2004) 1.02

Measurement of dopamine transporter occupancy for multiple injections of cocaine using a single injection of [F-18]FECNT. Synapse (2002) 1.02

A positron emission tomography study of methylphenidate in adults with ADHD: alterations in resting blood flow and predicting treatment response. Neuropsychopharmacology (2003) 1.02

Transport mechanisms of trans-1-amino-3-fluoro[1-(14)C]cyclobutanecarboxylic acid in prostate cancer cells. Nucl Med Biol (2011) 1.01

Interaction of cocaine and dopamine transporter inhibitors on behavior and neurochemistry in monkeys. Pharmacol Biochem Behav (2005) 1.00

Non-natural amino acids for tumor imaging using positron emission tomography and single photon emission computed tomography. Cancer Metastasis Rev (2008) 0.99

Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent. Bioorg Med Chem (2012) 0.99

Cortical activation during cocaine use and extinction in rhesus monkeys. Psychopharmacology (Berl) (2009) 0.99

Regularized image reconstruction algorithms for positron emission tomography. IEEE Trans Med Imaging (2004) 0.98

In vivo comparison of the reinforcing and dopamine transporter effects of local anesthetics in rhesus monkeys. Synapse (2005) 0.98

Dietary intake of soy genistein is associated with lung function in patients with asthma. J Asthma (2004) 0.98

Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clin Cancer Res (2012) 0.97

Childhood maltreatment is associated with a sex-dependent functional reorganization of a brain inhibitory control network. Hum Brain Mapp (2013) 0.95

The neural correlates of mate competition in dominant male rhesus macaques. Biol Psychiatry (2004) 0.95

Synthesis, fluorine-18 radiolabeling, and biological evaluation of N-((E)-4-fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-halophenyl)nortropanes: candidate radioligands for in vivo imaging of the brain dopamine transporter with positron emission tomography. J Med Chem (2010) 0.94

Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates. Neuropsychopharmacology (2013) 0.93

Synthesis and in vivo evaluation of fluorine-18 and iodine-123 labeled 2beta-carbo(2-fluoroethoxy)-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane as a candidate serotonin transporter imaging agent. J Med Chem (2007) 0.93

Functional reorganization of neural networks during repeated exposure to the traumatic memory in posttraumatic stress disorder: an exploratory fMRI study. J Psychiatr Res (2013) 0.93

Neuroeconomics and adolescent substance abuse: individual differences in neural networks and delay discounting. J Am Acad Child Adolesc Psychiatry (2013) 0.92

Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors. Bioorg Med Chem (2012) 0.91

Neural processing correlates of assaultive violence exposure and PTSD symptoms during implicit threat processing: a network-level analysis among adolescent girls. Psychiatry Res (2013) 0.90

Role of dopamine transporters in the behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in nonhuman primates. Psychopharmacology (Berl) (2009) 0.90

Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use. Neuropsychopharmacology (2012) 0.90

Radiolabeled amino acids for tumor imaging with PET: radiosynthesis and biological evaluation of 2-amino-3-[18F]fluoro-2-methylpropanoic acid and 3-[18F]fluoro-2-methyl-2-(methylamino)propanoic acid. J Med Chem (2002) 0.90

Individual kidney blood flow measured with contrast-enhanced first-pass perfusion MR imaging. Radiology (2008) 0.90

Magnetic resonance nephrourography: current and developing techniques. Radiol Clin North Am (2008) 0.90

Semi-automated preparation of the dopamine transporter ligand [(18)F]FECNT for human PET imaging studies. Appl Radiat Isot (2005) 0.90

Acute brain metabolic effects of cocaine in rhesus monkeys with a history of cocaine use. Brain Imaging Behav (2010) 0.90

Comparative evaluation of transport mechanisms of trans-1-amino-3-[¹⁸F]fluorocyclobutanecarboxylic acid and L-[methyl-¹¹C]methionine in human glioma cell lines. Brain Res (2013) 0.90

18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas. J Nucl Med (2013) 0.89

Functional brain imaging alterations in acne patients treated with isotretinoin. Am J Psychiatry (2005) 0.89

The immunophilin ligand GPI1046 protects neurons from the lethal effects of the HIV-1 proteins gp120 and Tat by modulating endoplasmic reticulum calcium load. J Neurochem (2006) 0.89

Establishing a new radiology residency research track. Acad Radiol (2012) 0.89

Synthesis of syn- and anti-1-amino-3-[18F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC), potential PET ligands for tumor detection. J Med Chem (2002) 0.89