Paul Fernyhough

Author PubWeight™ 33.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia. Diabetes 2003 1.50
2 Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress. Diabetes 2009 1.22
3 Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats. Diabetes 2010 1.18
4 Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment. Diabetes 2010 1.17
5 Mitochondrial malfunction and Ca2+ dyshomeostasis drive neuronal pathology in diabetes. Cell Calcium 2008 1.17
6 Distal degenerative sensory neuropathy in a long-term type 2 diabetes rat model. Diabetes 2008 1.16
7 Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons. Mol Cell Neurosci 2005 1.15
8 The role of aberrant mitochondrial bioenergetics in diabetic neuropathy. Neurobiol Dis 2012 1.13
9 Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes. Brain 2012 1.10
10 Alpha7 integrin mediates neurite outgrowth of distinct populations of adult sensory neurons. Mol Cell Neurosci 2005 1.07
11 4-Hydroxy-2-nonenal induces mitochondrial dysfunction and aberrant axonal outgrowth in adult sensory neurons that mimics features of diabetic neuropathy. Neurotox Res 2009 1.05
12 Growth factors as therapeutics for diabetic neuropathy. Curr Drug Targets 2008 1.04
13 Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal alpha5 integrin. Mol Cell Neurosci 2007 1.00
14 Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes. Mitochondrion 2011 0.96
15 Nuclear factor-kappaB activation in axons and Schwann cells in experimental sciatic nerve injury and its role in modulating axon regeneration: studies with etanercept. J Neuropathol Exp Neurol 2009 0.92
16 Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells. Eur J Neurosci 2007 0.92
17 Expression of hexokinase isoforms in the dorsal root ganglion of the adult rat and effect of experimental diabetes. Brain Res 2007 0.91
18 Role of oxidative stress in rabies virus infection of adult mouse dorsal root ganglion neurons. J Virol 2010 0.90
19 Blockade of hexokinase activity and binding to mitochondria inhibits neurite outgrowth in cultured adult rat sensory neurons. Neurosci Lett 2008 0.89
20 Ciliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents. Neuropharmacology 2012 0.87
21 Rabies virus phosphoprotein interacts with mitochondrial Complex I and induces mitochondrial dysfunction and oxidative stress. J Neurovirol 2015 0.86
22 Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats. Diabetes 2003 0.86
23 Role of oxidative stress in rabies virus infection. Adv Virus Res 2011 0.83
24 Receptor for advanced glycation end-products (RAGE) activates divergent signaling pathways to augment neurite outgrowth of adult sensory neurons. Exp Neurol 2013 0.82
25 Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the JAK/STAT pathway in cultured sensory neurons derived from streptozotocin-induced diabetic rodents. Cell Mol Neurobiol 2014 0.82
26 Tumor necrosis factor-α elevates neurite outgrowth through an NF-κB-dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy. Brain Res 2011 0.81
27 Peripheral axon crush elevates transport of p75NTR in the central projection of sensory neurones of rats. Neurosci Lett 2003 0.79
28 Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons. Mol Brain 2013 0.77
29 Role of nuclear factor-κB in oxidative stress associated with rabies virus infection of adult rat dorsal root ganglion neurons. J Virol 2012 0.77
30 Guaifenesin derivatives promote neurite outgrowth and protect diabetic mice from neuropathy. J Med Chem 2013 0.77
31 Functional magnetic resonance imaging of the spinal cord during sensory stimulation in diabetic rats. J Magn Reson Imaging 2009 0.77
32 Sensory neurons derived from diabetic rats have diminished internal Ca2+ stores linked to impaired re-uptake by the endoplasmic reticulum. ASN Neuro 2012 0.77
33 Mitochondrial dysfunction in rabies virus infection of neurons. J Neurovirol 2013 0.77
34 Activation of JNK in sensory neurons protects against sensory neuron cell death in diabetes and on exposure to glucose/oxidative stress in vitro. Ann N Y Acad Sci 2003 0.76
35 Temporal dystrophic remodeling within the intrinsic cardiac nervous system of the streptozotocin-induced diabetic rat model. Acta Neuropathol Commun 2014 0.75
36 Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 2017 0.75