|
1
|
Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B.
|
Science
|
1995
|
2.83
|
|
2
|
The extent of linkage disequilibrium in four populations with distinct demographic histories.
|
Am J Hum Genet
|
2000
|
2.03
|
|
3
|
RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes.
|
Clin Cancer Res
|
1998
|
2.00
|
|
4
|
Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.
|
J Clin Invest
|
1992
|
1.52
|
|
5
|
The human eps15 gene, encoding a tyrosine kinase substrate, is conserved in evolution and maps to 1p31-p32.
|
Oncogene
|
1994
|
1.18
|
|
6
|
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival.
|
Cancer Res
|
2000
|
1.06
|
|
7
|
Factors associated with climacteric symptoms in women around menopause attending menopause clinics in Italy.
|
Maturitas
|
2005
|
1.03
|
|
8
|
Dysfunction of the RET receptor in human cancer.
|
Cell Mol Life Sci
|
2004
|
0.98
|
|
9
|
Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKS): evidence for a divergence of the ERKs and JNKs pathways induced by Ret.
|
Oncogene
|
1998
|
0.95
|
|
10
|
Mutations in the extracellular domain cause RET loss of function by a dominant negative mechanism.
|
Mol Cell Biol
|
1998
|
0.92
|
|
11
|
Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours.
|
Br J Cancer
|
1993
|
0.91
|
|
12
|
Ret-mediated mitogenesis requires Src kinase activity.
|
Cancer Res
|
1999
|
0.90
|
|
13
|
The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.
|
Oncogene
|
2001
|
0.86
|
|
14
|
[Giardia duodenalis infections in pediatrics: our series].
|
Infez Med
|
1996
|
0.85
|
|
15
|
Risk factors for type 2 diabetes in women attending menopause clinics in Italy: a cross-sectional study.
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Climacteric
|
2005
|
0.83
|
|
16
|
Molecular biology of the MEN2 gene.
|
J Intern Med
|
1998
|
0.83
|
|
17
|
Molecular mechanisms of RET activation in human neoplasia.
|
J Endocrinol Invest
|
1999
|
0.81
|
|
18
|
Evolutionary conservation of the EPS8 gene and its mapping to human chromosome 12q23-q24.
|
Oncogene
|
1994
|
0.80
|
|
19
|
Frequent RET protooncogene mutations in multiple endocrine neoplasia type 2A.
|
J Clin Endocrinol Metab
|
1994
|
0.80
|
|
20
|
RET/PTC activation in human thyroid carcinomas.
|
J Endocrinol Invest
|
1995
|
0.79
|
|
21
|
Cloning of the rat tissue inhibitor of metalloproteinases type 2 (TIMP-2) gene: analysis of its expression in normal and transformed thyroid cells.
|
Exp Cell Res
|
1994
|
0.78
|
|
22
|
[Diagnosis in endodontics. I].
|
Minerva Stomatol
|
1987
|
0.75
|
|
23
|
Genetic alterations in differentiated thyroid cancer: what can be expected for gene expression profiling of thyroid carcinomas.
|
Ann Endocrinol (Paris)
|
2003
|
0.75
|
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24
|
[A case of bilateral ovarian cystoadenofibroma].
|
Pathologica
|
1981
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0.75
|
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25
|
[Healing of radicular cysts by root canal therapy alone. 3].
|
Minerva Stomatol
|
1988
|
0.75
|
|
26
|
Different mutations of the RET gene cause different human tumoral diseases.
|
Biochimie
|
1999
|
0.75
|
|
27
|
[New method of regluing a crown fragment on an endodontically treated tooth].
|
Minerva Stomatol
|
1986
|
0.75
|
|
28
|
[Conservative therapy of coronal fractures with reattachment of the original fragment: indications for periodontal treatment].
|
Arch Stomatol (Napoli)
|
1989
|
0.75
|
|
29
|
Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential.
|
Endocrinology
|
1997
|
0.75
|