W C Parks

Author PubWeight™ 123.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science 1998 8.16
2 Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 2000 6.62
3 Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science 1999 6.49
4 Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages. J Clin Invest 1995 2.53
5 Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. J Biol Chem 2001 2.40
6 The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J Cell Biol 1997 2.29
7 Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization. Am J Pathol 1989 2.02
8 Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during excisional skin wound repair. Exp Cell Res 1998 2.01
9 Matrilysin expression and function in airway epithelium. J Clin Invest 1998 1.94
10 Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme. Proc Natl Acad Sci U S A 1996 1.92
11 Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol 1996 1.72
12 Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase. J Vasc Surg 1996 1.66
13 Role of matrix metalloproteinases in abdominal aortic aneurysms. Ann N Y Acad Sci 1996 1.59
14 Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin. Am J Pathol 2000 1.59
15 Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J Clin Invest 1993 1.56
16 Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest 1994 1.52
17 Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury. J Biol Chem 2000 1.48
18 Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension. Science 1987 1.47
19 Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen. J Biol Chem 2001 1.46
20 Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest 1992 1.45
21 Bacterial exposure induces and activates matrilysin in mucosal epithelial cells. J Cell Biol 2000 1.41
22 PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell 1991 1.41
23 Matrix metalloproteinase matrilysin is constitutively expressed in adult human exocrine epithelium. J Invest Dermatol 1995 1.40
24 Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J Immunol 1995 1.38
25 Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene. Gene 2000 1.37
26 Pathogenesis of abdominal aortic aneurysms: a multidisciplinary research program supported by the National Heart, Lung, and Blood Institute. J Vasc Surg 2001 1.29
27 92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen. J Clin Invest 1994 1.26
28 Extracellular matrix protein gene expression in atherosclerotic hypertensive pulmonary arteries. Am J Pathol 1992 1.25
29 Developmental regulation of elastin production. Expression of tropoelastin pre-mRNA persists after down-regulation of steady-state mRNA levels. J Biol Chem 1995 1.23
30 Binding of elastin to Staphylococcus aureus. J Biol Chem 1991 1.21
31 Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J Biol Chem 1993 1.20
32 92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma. Am J Pathol 1993 1.18
33 Role of matrix metalloproteinases and their inhibition in cutaneous wound healing and allergic contact hypersensitivity. Ann N Y Acad Sci 1999 1.16
34 Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury. Am J Pathol 1996 1.13
35 Re-epithelialization of human oral keratinocytes in vitro. J Dent Res 1996 1.08
36 Mechanisms of hepatocyte growth factor stimulation of keratinocyte metalloproteinase production. J Biol Chem 1996 1.07
37 Regulation of matrilysin expression in airway epithelial cells by Pseudomonas aeruginosa flagellin. J Biol Chem 2001 1.07
38 Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma. J Invest Dermatol 1992 1.07
39 Matrilysin expression by human mononuclear phagocytes and its regulation by cytokines and hormones. J Immunol 1995 1.07
40 Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors. Proc Natl Acad Sci U S A 2001 1.06
41 Regulation of the expression of stromelysin-2 by growth factors in keratinocytes: implications for normal and impaired wound healing. Biochem J 1996 1.05
42 Interstitial collagenase is expressed by keratinocytes that are actively involved in reepithelialization in blistering skin disease. J Invest Dermatol 1995 1.05
43 Fibrillin-1 and fibrillin-2 show temporal and tissue-specific regulation of expression in developing elastic tissues. Connect Tissue Res 1995 1.04
44 Active collagen synthesis by pulmonary arteries in human primary pulmonary hypertension. Am J Pathol 1993 1.04
45 Induction and repression of collagenase-1 by keratinocytes is controlled by distinct components of different extracellular matrix compartments. J Biol Chem 1997 1.03
46 Human dermal microvascular endothelial cells produce matrix metalloproteinases in response to angiogenic factors and migration. J Invest Dermatol 1995 1.02
47 Medial neovascularization in abdominal aortic aneurysms: a histopathologic marker of aneurysmal degeneration with pathophysiologic implications. J Vasc Surg 1995 1.01
48 Transforming growth factor-beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries. J Clin Invest 1992 1.01
49 Expression of interstitial collagenase, 92-kDa gelatinase, and tissue inhibitor of metalloproteinases-1 in granuloma annulare and necrobiosis lipoidica diabeticorum. J Invest Dermatol 1993 1.00
50 Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities. J Biol Chem 1994 1.00
51 Insulin mediates the stimulation of pyruvate kinase by a dual mechanism. Biochem J 1982 1.00
52 Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension. Am J Pathol 1994 0.99
53 Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. J Biol Chem 1997 0.99
54 Neointimal macrophages colocalize with extracellular matrix gene expression in human atherosclerotic pulmonary arteries. J Clin Invest 1993 0.99
55 Glucocorticoids upregulate tropoelastin expression during late stages of fetal lung development. Am J Physiol 1995 0.97
56 Identification of multiple tropoelastins secreted by bovine cells. J Biol Chem 1987 0.95
57 Polyclonal antibodies to tropoelastin and the specific detection and measurement of tropoelastin in vitro. Connect Tissue Res 1991 0.94
58 Smooth muscle isoactin and elastin in fetal bovine lung. Exp Lung Res 1989 0.94
59 Inhibition of tropoelastin expression by 1,25-dihydroxyvitamin D3. Connect Tissue Res 1991 0.94
60 Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension. Am Rev Respir Dis 1989 0.92
61 Cellular adaptation during chronic neonatal hypoxic pulmonary hypertension. Am J Physiol 1991 0.92
62 Vascular remodeling in neonatal pulmonary hypertension. Role of the smooth muscle cell. Chest 1988 0.91
63 Structural analysis of the alpha(2) integrin I domain/procollagenase-1 (matrix metalloproteinase-1) interaction. J Biol Chem 2001 0.90
64 Neutral proteinase expression by human mononuclear phagocytes: a prominent role of cellular differentiation. Matrix Suppl 1992 0.90
65 Collagenase-1 and collagen in epidermal repair. Arch Dermatol Res 1998 0.90
66 Localization of type I procollagen gene expression in silica-induced granulomatous lung disease and implication of transforming growth factor-beta as a mediator of fibrosis. Am J Pathol 1996 0.89
67 Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism. Circulation 2011 0.89
68 An open reading frame element mediates posttranscriptional regulation of tropoelastin and responsiveness to transforming growth factor beta1. Mol Cell Biol 1999 0.89
69 Insulin-like growth factor I stimulates elastin synthesis by bovine pulmonary arterial smooth muscle cells. Biochem Biophys Res Commun 1989 0.88
70 Rapid alterations induced by insulin in hepatocyte ultrastructure and glycogen levels. Am J Anat 1981 0.88
71 p38 mitogen-activated kinase is a bidirectional regulator of human fibroblast collagenase-1 induction by three-dimensional collagen lattices. Biochem J 2001 0.87
72 1,25-Dihydroxyvitamin D3 represses tropoelastin expression by a posttranscriptional mechanism. J Biol Chem 1992 0.87
73 Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension. J Clin Invest 1994 0.87
74 Keratinocyte collagenase-1 expression requires an epidermal growth factor receptor autocrine mechanism. J Biol Chem 1999 0.87
75 Osteopontin expression is increased in the heritable cardiomyopathy of Syrian hamsters. Circulation 1995 0.86
76 Fibroblasts from patients with inherited predisposition to retinoblastoma exhibit normal sensitivity to the mutagenic effects of ionizing radiation. Mutat Res 1986 0.86
77 Distinct mechanisms regulate TIMP-1 expression at different stages of phorbol ester-mediated differentiation of U937 cells. Biochemistry 1997 0.85
78 Modulation of intracellular calcium levels inhibits secretion of collagenase 1 by migrating keratinocytes. Mol Biol Cell 1997 0.84
79 Collagenase-1 complexes with alpha2-macroglobulin in the acute and chronic wound environments. J Invest Dermatol 1998 0.84
80 Purification and characterization of bovine interstitial collagenase and tissue inhibitor of metalloproteinases. Arch Biochem Biophys 1992 0.84
81 Collagenase-I, stromelysin-I, and matrilysin are expressed within the placenta during multiple stages of human pregnancy. Placenta 1996 0.83
82 Cell type-specific inhibition of keratinocyte collagenase-1 expression by basic fibroblast growth factor and keratinocyte growth factor. A common receptor pathway. J Biol Chem 1997 0.83
83 Uncoordinate regulation of collagenase, stromelysin, and tissue inhibitor of metalloproteinases genes by prostaglandin E2: selective enhancement of collagenase gene expression in human dermal fibroblasts in culture. J Cell Biochem 1994 0.81
84 Molecular mechanisms regulating the production of collagenase and TIMP in U937 cells: evidence for involvement of delayed transcriptional activation and enhanced mRNA stability. Biochemistry 1993 0.81
85 Fibroblast adhesion to recombinant tropoelastin expressed as a protein A-fusion protein. Biochem J 1991 0.81
86 Conversion to an elastogenic phenotype by fetal hyaline chondrocytes is accompanied by altered expression of elastin-related macromolecules. Dev Biol 1994 0.80
87 Angiotensin converting enzyme expression in primary pulmonary hypertension. Am J Respir Crit Care Med 1996 0.79
88 Effects of 20 months of ozone exposure on lung collagen in Fischer 344 rats. Toxicology 1993 0.78
89 Spatial pattern of type I collagen expression in injured peripheral nerve. J Neurosurg 1997 0.77
90 Insulin stimulation of hepatic malic enzyme activity in normal and diabetic rats controlled by different regulatory processes. J Biol Chem 1983 0.77
91 In situ hybridization of human erythropoietin in pre- and postnatal kidneys. Pediatr Pathol Lab Med 1996 0.76
92 The regulation of collagen in fetal skin wounds: mRNA localization and analysis. J Pediatr Surg 1994 0.76
93 Recent advances in molecular biological techniques and their relevance to pulmonary research. Thorax 2000 0.75
94 Connective tissue production by vascular smooth muscle in development and disease. Chest 1991 0.75
95 Posttranscriptional regulation of lung elastin expression involves binding of a developmentally regulated cytosolic protein to an open-reading frame cis-element in the messenger RNA. Chest 1999 0.75
96 Increased mesenchymal cell density accompanies induction of tropoelastin expression in developing elastic tissue. Dev Dyn 1994 0.75
97 Abnormal hepatic lipid accumulation following treatment of diabetic rats with insulin and a high-carbohydrate, fat-free diet. Am J Anat 1983 0.75
98 Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part XI: Integrative Summary. Res Rep Health Eff Inst 1995 0.75
99 Hypoxia-induced inhibition of tropoelastin synthesis by neonatal calf pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol 1991 0.75
100 Human cell-mediated cytotoxicity, mutagenicity, and DNA adduct formation of 7H-dibenzo(c,g)carbazole and its N-methyl derivative in diploid human fibroblasts. Cancer Res 1986 0.75