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1
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A mammalian microRNA expression atlas based on small RNA library sequencing.
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Cell
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2007
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34.03
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2
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Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group.
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J Clin Oncol
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2010
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4.09
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3
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Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia.
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Blood
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2007
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3.64
|
|
4
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Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
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J Exp Med
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2008
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3.24
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5
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Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.
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Proc Natl Acad Sci U S A
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2009
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2.54
|
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6
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Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.
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Blood
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2011
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2.44
|
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7
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IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report.
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J Clin Oncol
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2009
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2.00
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8
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Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.
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Blood
|
2012
|
1.88
|
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9
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BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.
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Blood
|
2008
|
1.78
|
|
10
|
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP).
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Blood
|
2009
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1.76
|
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11
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Spontaneous regression of chronic lymphocytic leukemia: clinical and biologic features of 9 cases.
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Blood
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2009
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1.74
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12
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NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL.
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Haematologica
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2011
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1.67
|
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13
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Protein kinase gene expression profiling and in vitro functional experiments identify novel potential therapeutic targets in adult acute lymphoblastic leukemia.
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Cancer
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2010
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1.40
|
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14
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An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase.
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Br J Haematol
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2008
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1.33
|
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15
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Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance.
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Blood
|
2008
|
1.28
|
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16
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Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor.
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Blood
|
2005
|
1.24
|
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17
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Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations.
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Neoplasia
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2009
|
1.23
|
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18
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Characterization of B- and T-lineage acute lymphoblastic leukemia by integrated analysis of MicroRNA and mRNA expression profiles.
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Genes Chromosomes Cancer
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2009
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1.21
|
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19
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IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.
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PLoS One
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2012
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1.15
|
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20
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The circulating dendritic cell compartment in patients with chronic lymphocytic leukemia is severely defective and unable to stimulate an effective T-cell response.
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Cancer Res
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2003
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1.11
|
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21
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Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness.
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Blood
|
2014
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1.09
|
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22
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Complete response to donor lymphocyte infusion in multiple myeloma is associated with antibody responses to highly expressed antigens.
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Blood
|
2003
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1.09
|
|
23
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ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression.
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Haematologica
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2011
|
1.08
|
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24
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T-cell acute lymphoblastic leukemia.
|
Haematologica
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2009
|
1.04
|
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25
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The changing scene of adult acute lymphoblastic leukemia.
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Curr Opin Oncol
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2006
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1.03
|
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26
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Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2.
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Genes Cancer
|
2011
|
0.99
|
|
27
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Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults.
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Haematologica
|
2010
|
0.98
|
|
28
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TP53 mutations are frequent in adult acute lymphoblastic leukemia cases negative for recurrent fusion genes and correlate with poor response to induction therapy.
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Haematologica
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2013
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0.96
|
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29
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Therapeutic potential of MEK inhibition in acute myelogenous leukemia: rationale for "vertical" and "lateral" combination strategies.
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J Mol Med (Berl)
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2012
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0.91
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30
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Bayesian error-in-variable survival model for the analysis of GeneChip arrays.
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Biometrics
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2005
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0.90
|
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31
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ALL-associated JAK1 mutations confer hypersensitivity to the antiproliferative effect of type I interferon.
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Blood
|
2010
|
0.90
|
|
32
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Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells.
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Blood
|
2012
|
0.87
|
|
33
|
Identification of different Ikaros cDNA transcripts in Philadelphia-positive adult acute lymphoblastic leukemia by a high-throughput capillary electrophoresis sizing method.
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Haematologica
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2008
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0.87
|
|
34
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Human acute stem cell leukemia with multilineage differentiation potential via cascade activation of growth factor receptors.
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Blood
|
2002
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0.87
|
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35
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Chlorambucil plus rituximab with or without maintenance rituximab as first-line treatment for elderly chronic lymphocytic leukemia patients.
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Am J Hematol
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2014
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0.86
|
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36
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A subset of chronic lymphocytic leukemia patients display reduced levels of PARP1 expression coupled with a defective irradiation-induced apoptosis.
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Exp Hematol
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2011
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0.86
|
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37
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SQSTM1-NUP214: a new gene fusion in adult T-cell acute lymphoblastic leukemia.
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Haematologica
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2010
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0.85
|
|
38
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Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212.
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Genes Chromosomes Cancer
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2015
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0.83
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39
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Behind the scenes of non-nodal MCL: downmodulation of genes involved in actin cytoskeleton organization, cell projection, cell adhesion, tumour invasion, TP53 pathway and mutated status of immunoglobulin heavy chain genes.
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Br J Haematol
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2011
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0.83
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40
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Gene expression profile of protein kinases reveals a distinctive signature in chronic lymphocytic leukemia and in vitro experiments support a role of second generation protein kinase inhibitors.
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Leuk Res
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2009
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0.80
|
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41
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Stereotyped subset #1 chronic lymphocytic leukemia: a direct link between B-cell receptor structure, function, and patients' prognosis.
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Am J Hematol
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2014
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0.80
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42
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Identification of molecular and functional patterns of p53 alterations in chronic lymphocytic leukemia patients in different phases of the disease.
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Haematologica
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2012
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0.80
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43
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FLT3 inhibition in t(4;11)+ adult acute lymphoid leukaemia.
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Br J Haematol
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2005
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0.79
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44
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DDX3X-MLLT10 fusion in adults with NOTCH1 positive T-cell acute lymphoblastic leukemia.
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Haematologica
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2014
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0.78
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45
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IgD cross-linking induces gene expression profiling changes and enhances apoptosis in chronic lymphocytic leukemia cells.
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Leuk Res
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2013
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0.78
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46
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DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study.
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Haematologica
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2011
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0.77
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47
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AICDA expression in BCR/ABL1-positive acute lymphoblastic leukaemia is associated with a peculiar gene expression profile.
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Br J Haematol
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2011
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0.77
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48
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Functional analysis and gene expression profile of umbilical cord blood regulatory T cells.
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Ann Hematol
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2011
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0.76
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49
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Whole-genome amplification for the detection of molecular targets and minimal residual disease monitoring in acute lymphoblastic leukaemia.
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Br J Haematol
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2014
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0.75
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50
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Management of adult patients with Philadelphia positive acute lymphoblastic leukemia.
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Rinsho Ketsueki
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2013
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0.75
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51
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A broad and integrated diagnostic work-up for a modern management of Acute Lymphoblastic Leukemia (ALL).
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Hematology
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2005
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0.75
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52
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A case of late isolated ovarian relapse of acute lymphoblastic leukemia after an allogeneic stem cell transplant.
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Leuk Lymphoma
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2014
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0.75
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