Seth J Orlow

Author PubWeight™ 69.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 p16(Ink4a) in melanocyte senescence and differentiation. J Natl Cancer Inst 2002 2.09
2 Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8. J Invest Dermatol 2012 2.02
3 IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis. J Invest Dermatol 2013 1.65
4 Patient perspectives on the management of atopic dermatitis. J Allergy Clin Immunol 2006 1.55
5 Symmetric truncal aplasia cutis congenita following multifetal reduction of a sextuplet pregnancy. J Pediatr 2008 1.48
6 Dissection of melanogenesis with small molecules identifies prohibitin as a regulator. Chem Biol 2005 1.48
7 Spitz nevi: beliefs, behaviors, and experiences of pediatric dermatologists. JAMA Dermatol 2013 1.46
8 Triazine-based tyrosinase inhibitors identified by chemical genetic screening. Pigment Cell Res 2005 1.40
9 Pink-eyed dilution protein controls the processing of tyrosinase. Mol Biol Cell 2002 1.29
10 Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells. Mol Cancer Res 2008 1.21
11 Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research. Am J Transl Res 2009 1.17
12 Pink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism. Mol Biol Cell 2002 1.14
13 The misnomer "macrocephaly-cutis marmorata telangiectatica congenita syndrome": report of 12 new cases and support for revising the name to macrocephaly-capillary malformations. Arch Dermatol 2009 1.10
14 Identification of novel pigmentation modulators by chemical genetic screening. J Invest Dermatol 2007 1.06
15 Pityriasis rubra pilaris, type IV. Dermatol Online J 2005 1.03
16 Practical guidelines for evaluation of loose anagen hair syndrome. Arch Dermatol 2009 1.02
17 Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions. J Invest Dermatol 2006 1.00
18 The Tyr (albino) locus of the laboratory mouse. Mamm Genome 2004 1.00
19 Evidence-based recommendations for the diagnosis and treatment of pediatric acne. Pediatrics 2013 1.00
20 Infantile systemic hyalinosis. J Am Acad Dermatol 2004 0.99
21 Porokeratotic eccrine ostial and dermal duct nevus: a report of 2 cases and review of the literature. Am J Dermatopathol 2009 0.99
22 Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation. Pigment Cell Res 2005 0.99
23 From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging. J Invest Dermatol 2009 0.99
24 "Pediatric blaschkitis": expanding the spectrum of childhood acquired Blaschko-linear dermatoses. Pediatr Dermatol 2007 0.96
25 Ocular albinism 1 protein: trafficking and function when expressed in Saccharomyces cerevisiae. Exp Eye Res 2005 0.96
26 Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies. J Am Acad Dermatol 2006 0.95
27 Planning for a brighter future: a review of sun protection and barriers to behavioral change in children and adolescents. Dermatol Online J 2008 0.94
28 Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells. Mol Cancer Res 2009 0.94
29 Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma. Melanoma Res 2010 0.94
30 Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking. Mol Pharmacol 2008 0.93
31 Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner. Mol Biol Cell 2004 0.92
32 The Dermatology Foundation: partnerships and programs focused on the future. J Invest Dermatol 2013 0.92
33 Extensive Riga-Fede disease of the lip and tongue. J Am Acad Dermatol 2002 0.91
34 Inhibition of mitochondrial protein translation sensitizes melanoma cells to arsenic trioxide cytotoxicity via a reactive oxygen species dependent mechanism. Cancer Chemother Pharmacol 2008 0.91
35 Mucosal dominant pemphigus vulgaris with anti-desmoplakin autoantibodies. J Am Acad Dermatol 2004 0.90
36 Experience with molluscum contagiosum and associated inflammatory reactions in a pediatric dermatology practice: the bump that rashes. Arch Dermatol 2012 0.90
37 The ocular albinism type 1 gene product, OA1, spans intracellular membranes 7 times. Exp Eye Res 2007 0.89
38 Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells. Mol Cancer Res 2009 0.88
39 Rab27b association with melanosomes: dominant negative mutants disrupt melanosomal movement. J Invest Dermatol 2002 0.88
40 Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways. Anticancer Res 2011 0.88
41 Mucocutaneous neuromas: an underrecognized manifestation of PTEN hamartoma-tumor syndrome. Arch Dermatol 2006 0.87
42 XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts. Anticancer Drugs 2013 0.86
43 Oral retinoid therapy for dermatologic conditions in children and adolescents. J Am Acad Dermatol 2003 0.86
44 Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A. Pigment Cell Res 2003 0.85
45 Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression. Exp Eye Res 2005 0.85
46 Pigmented plexiform neurofibroma: Distinction from a large congenital melanocytic nevus. J Am Acad Dermatol 2007 0.84
47 The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding. Pigment Cell Melanoma Res 2010 0.84
48 Abortive segmental perineal hemangioma. Dermatol Online J 2011 0.84
49 Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish. Mol Biosyst 2005 0.84
50 Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways. Oncol Rep 2012 0.83
51 Radiation therapy for high-risk squamous cell carcinomas in patients with xeroderma pigmentosum: report of two cases and review of the literature. Dermatology 2011 0.82
52 Treatment of children and adolescents with methotrexate, cyclosporine, and etanercept: review of the dermatologic and rheumatologic literature. J Am Acad Dermatol 2005 0.82
53 Correction of defective early tyrosinase processing by bafilomycin A1 and monensin in pink-eyed dilution melanocytes. Pigment Cell Res 2004 0.81
54 Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism. Leuk Res 2009 0.81
55 Cole Disease Results from Mutations in ENPP1. Am J Hum Genet 2013 0.80
56 25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase. Pigment Cell Res 2004 0.80
57 Albendazole sensitizes cancer cells to ionizing radiation. Radiat Oncol 2011 0.79
58 Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism. Chem Biol 2004 0.78
59 Chemical genetic screening identifies tricyclic compounds that decrease cellular melanin content. J Invest Dermatol 2007 0.77
60 Cole disease: guttate hypopigmentation and punctate palmoplantar keratoderma. Arch Dermatol 2009 0.77
61 Efficacy and safety of oral retinoids in psoriasis. Expert Opin Drug Saf 2005 0.77
62 Lichen planopilaris noted during etanercept therapy in a child with severe psoriasis. Pediatr Dermatol 2009 0.77
63 Congenital Spitz nevus clinically mimicking melanoma. J Am Acad Dermatol 2002 0.76
64 Juvenile myelomonocytic leukemia presenting with features of hemophagocytic lymphohistiocytosis in association with neurofibromatosis and juvenile xanthogranulomas. J Pediatr Hematol Oncol 2004 0.76
65 X-linked recessive ichthyosis. Dermatol Online J 2005 0.76
66 The physician-scientist. J Invest Dermatol 2006 0.76
67 Loss of Oca2 disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes. Pigment Cell Melanoma Res 2013 0.76
68 Patient-reported outcomes in pediatric patients with psoriasis undergoing etanercept treatment: 12-week results from a phase III randomized controlled trial. J Am Acad Dermatol 2010 0.76
69 Informed reasoning: repositioning of nitisinone to treat oculocutaneous albinism. J Clin Invest 2011 0.75
70 Identification of agents that promote endoplasmic reticulum stress using an assay that monitors luciferase secretion. J Biomol Screen 2013 0.75
71 Melanocytic proliferations in the setting of vulvar lichen sclerosus: diagnostic considerations. Pediatr Dermatol 2005 0.75
72 Engineering a new mouse model for vitiligo. J Invest Dermatol 2012 0.75
73 Phacomatosis pigmentokeratotica associated with hemihypertrophy and a rhabdomyosarcoma of the abdominal wall. J Am Acad Dermatol 2006 0.75
74 Morphea, diabetes mellitus type I, and celiac disease: case report and review of the literature. Pediatr Dermatol 2010 0.75
75 Eccrine angiomatous hamartoma. Dermatol Online J 2006 0.75
76 Juvenile amyopathic dermatomyositis. Dermatol Online J 2005 0.75
77 Cutaneous features of Crouzon syndrome with acanthosis nigricans. JAMA Dermatol 2013 0.75
78 Infantile granular parakeratosis: recognition of two clinical patterns. J Am Acad Dermatol 2004 0.75
79 Dermatologists' attitudes, prescription, and counseling patterns for isotretinoin: a questionnaire-based study. J Drugs Dermatol 2015 0.75