PubRank

Tobias B Huber

Author PubWeight™ 102.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 2010 3.44
3 AKT2 is essential to maintain podocyte viability and function during chronic kidney disease. Nat Med 2013 3.41
4 Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 2011 2.90
5 FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nat Genet 2012 2.74
6 mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest 2011 2.72
7 Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury. Kidney Int 2012 2.55
8 A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation. Sci Signal 2012 2.36
9 Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc Natl Acad Sci U S A 2008 2.12
10 Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. EMBO J 2005 2.12
11 Proteinuria impairs podocyte regeneration by sequestering retinoic acid. J Am Soc Nephrol 2013 2.09
12 Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol 2011 2.04
13 NEPH1 defines a novel family of podocin interacting proteins. FASEB J 2002 1.85
14 Anthracyclines induce DNA damage response-mediated protection against severe sepsis. Immunity 2013 1.83
15 Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1. J Am Soc Nephrol 2003 1.83
16 Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proc Natl Acad Sci U S A 2009 1.57
17 Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int 2013 1.55
18 CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. J Clin Invest 2011 1.49
19 Albumin-associated free fatty acids induce macropinocytosis in podocytes. J Clin Invest 2015 1.46
20 Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy 2012 1.44
21 Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem 2008 1.43
22 mTORC2 critically regulates renal potassium handling. J Clin Invest 2016 1.40
23 KIBRA modulates directional migration of podocytes. J Am Soc Nephrol 2008 1.36
24 Unraveling the role of podocyte turnover in glomerular aging and injury. J Am Soc Nephrol 2014 1.36
25 Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia. EMBO J 2005 1.35
26 ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet 2013 1.32
27 Identification of a novel inhibitory actin-capping protein binding motif in CD2-associated protein. J Biol Chem 2006 1.23
28 Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy. N Engl J Med 2015 1.17
29 CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency. J Biol Chem 2005 1.15
30 The podocyte slit diaphragm--from a thin grey line to a complex signalling hub. Nat Rev Nephrol 2013 1.12
31 How many ways can a podocyte die? Semin Nephrol 2012 1.12
32 Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis. J Am Soc Nephrol 2013 1.09
33 Implications of autophagy for glomerular aging and disease. Cell Tissue Res 2011 1.05
34 A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis. Hum Mol Genet 2010 1.05
35 mTOR controls kidney epithelia in health and disease. Nephrol Dial Transplant 2014 1.00
36 Expression and function of C/EBP homology protein (GADD153) in podocytes. Am J Pathol 2006 0.97
37 Podocyte polarity signalling. Curr Opin Nephrol Hypertens 2009 0.93
38 New players in the pathogenesis of focal segmental glomerulosclerosis. Nephrol Dial Transplant 2012 0.93
39 Mammalian target of rapamycin signaling in the podocyte. Curr Opin Nephrol Hypertens 2012 0.93
40 Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling. J Neuroendocrinol 2013 0.91
41 Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 2015 0.90
42 Role of the polarity protein Scribble for podocyte differentiation and maintenance. PLoS One 2012 0.90
43 N-wasp is required for stabilization of podocyte foot processes. J Am Soc Nephrol 2013 0.87
44 Podocyte regeneration: who can become a podocyte? Am J Pathol 2013 0.87
45 Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes. FASEB J 2003 0.87
46 Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy. Diabetes 2013 0.87
47 An update on ABO-incompatible kidney transplantation. Transpl Int 2014 0.86
48 Flying podocytes. Kidney Int 2009 0.85
49 Immunosuppression for membranous nephropathy. Lancet 2013 0.85
50 aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation. J Am Soc Nephrol 2013 0.85
51 Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. Hum Genet 2015 0.84
52 GSK3β inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility. Am J Physiol Renal Physiol 2011 0.83
53 Zona occludens proteins modulate podosome formation and function. FASEB J 2010 0.82
54 A novel domain regulating degradation of the glomerular slit diaphragm protein podocin in cell culture systems. PLoS One 2013 0.81
55 Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis. PLoS One 2011 0.80
56 The class III phosphatidylinositol 3-kinase PIK3C3/VPS34 regulates endocytosis and autophagosome-autolysosome formation in podocytes. Autophagy 2013 0.78
57 Chromatin dynamics in kidney development and function. Cell Tissue Res 2014 0.78
58 Functional study of mammalian Neph proteins in Drosophila melanogaster. PLoS One 2012 0.78
59 Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι. Am J Pathol 2013 0.78
60 Signaling at the slit: podocytes chat by synaptic transmission. J Am Soc Nephrol 2009 0.76
61 Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury. J Clin Invest 2016 0.76
62 Molecular understanding of the slit diaphragm. Pediatr Nephrol 2012 0.76
63 The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins. Mol Cell Biol 2011 0.75
64 Old friends form alliance against podocytes. Kidney Int 2011 0.75
65 A brief overview on IRM function across evolution. J Neurogenet 2014 0.75
66 The long journey through renal filtration: new pieces in the puzzle of slit diaphragm architecture. Curr Opin Nephrol Hypertens 2017 0.75
67 Is podocyte research at a tipping point? Report from the 9(th) International Podocyte Conference. Kidney Int 2012 0.75