Luis Alvarez-Vallina

Author PubWeight™ 32.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM. J Biol Chem 2004 2.33
2 Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells. Nat Biotechnol 2002 1.48
3 CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors. Mol Ther Nucleic Acids 2013 1.45
4 Multivalent antibodies: when design surpasses evolution. Trends Biotechnol 2010 1.28
5 Antibody engineering: facing new challenges in cancer therapy. Acta Pharmacol Sin 2005 1.14
6 In vivo tumor targeting and imaging with engineered trivalent antibody fragments containing collagen-derived sequences. PLoS One 2009 1.02
7 Cells as vehicles for cancer gene therapy: the missing link between targeted vectors and systemic delivery? Hum Gene Ther 2002 1.00
8 Antibodies and gene therapy: teaching old 'magic bullets' new tricks. Trends Immunol 2004 0.99
9 Selection of functional human antibodies from retroviral display libraries. Nucleic Acids Res 2005 0.97
10 A novel cell binding site in the coiled-coil domain of laminin involved in capillary morphogenesis. EMBO J 2003 0.94
11 Induction of human T lymphocyte cytotoxicity and inhibition of tumor growth by tumor-specific diabody-based molecules secreted from gene-modified bystander cells. J Immunol 2003 0.94
12 The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies. J Biol Chem 2010 0.94
13 Enhanced antiangiogenic therapy with antibody-collagen XVIII NC1 domain fusion proteins engineered to exploit matrix remodeling events. Int J Cancer 2006 0.92
14 Chronic gene delivery of interferon-inducible protein 10 through replication-competent retrovirus vectors suppresses tumor growth. Cancer Gene Ther 2005 0.91
15 Functional improvement of antibody fragments using a novel phage coat protein III fusion system. Biochem Biophys Res Commun 2002 0.90
16 Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies. Proc Natl Acad Sci U S A 2013 0.90
17 Lymphocyte display: a novel antibody selection platform based on T cell activation. PLoS One 2009 0.88
18 Development of a computer-assisted high-throughput screening platform for anti-angiogenic testing. Microvasc Res 2002 0.86
19 The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype. PLoS One 2012 0.85
20 Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C. Biochem J 2005 0.83
21 Virotherapy, gene transfer and immunostimulatory monoclonal antibodies. Oncoimmunology 2012 0.83
22 Gene expression profiling identifies EPHB4 as a potential predictive biomarker in colorectal cancer patients treated with bevacizumab. Med Oncol 2013 0.83
23 Antibody engineering, virus retargeting and cellular immunotherapy: one ring to rule them all? Curr Gene Ther 2005 0.82
24 Antibody gene therapy: getting closer to clinical application? Curr Gene Ther 2013 0.81
25 Enhancement of DNA vaccine potency through linkage of antigen to filamentous bacteriophage coat protein III domain I. Immunology 2006 0.80
26 Autocrine costimulation: tumor-specific CD28-mediated costimulation of T cells by in situ production of a bifunctional B7-anti-CEA diabody fusion protein. Cancer Gene Ther 2002 0.80
27 The extracellular matrix: a new turn-of-the-screw for anti-angiogenic strategies. Trends Mol Med 2003 0.80
28 Replicating retroviral vectors mediating continuous production and secretion of therapeutic gene products from cancer cells. Cancer Gene Ther 2005 0.79
29 The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-treated mice. Mol Ther 2012 0.78
30 Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis. PLoS One 2013 0.77
31 In vivo selection of tumor-specific antibodies. Oncotarget 2013 0.76
32 Generation of non-permissive basement membranes by anti-laminin antibody fragments produced by matrix-embedded gene-modified cells. Cancer Immunol Immunother 2003 0.76
33 Adenovirus E1a protein enhances the cytotoxic effects of the herpes thymidine kinase-ganciclovir system. Cancer Gene Ther 2003 0.76
34 Comment on "Production of multivalent protein binders using a self-trimerization collagen-like peptide scaffold". FASEB J 2008 0.75
35 Functionally fused antibodies--a novel adjuvant fusion system. J Immunol Methods 2008 0.75
36 Antibody-based antiangiogenic cancer therapy. Expert Opin Ther Targets 2005 0.75
37 Establishment of an immortalized PARP-1-/- murine endothelial cell line: a new tool to study PARP-1 mediated endothelial cell dysfunction. J Cell Biochem 2005 0.75