PubRank

Hubert Kalbacher

Author PubWeight™ 113.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections. Nat Med 2004 5.21
2 Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci U S A 2005 3.75
3 Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med 2010 3.60
4 The bacterial defensin resistance protein MprF consists of separable domains for lipid lysinylation and antimicrobial peptide repulsion. PLoS Pathog 2009 1.94
5 The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity. J Gen Physiol 2005 1.57
6 Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent. J Gen Physiol 2006 1.51
7 Cathepsin D: a cellular roadmap. Biochem Biophys Res Commun 2008 1.33
8 Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1. J Biol Chem 2004 1.26
9 The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange. Biochemistry 2002 1.24
10 Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat. Eur J Neurosci 2006 1.21
11 Contamination risks in work with synthetic peptides: flg22 as an example of a pirate in commercial peptide preparations. Plant Cell 2012 1.20
12 Structural basis of cell wall cleavage by a staphylococcal autolysin. PLoS Pathog 2010 1.20
13 Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo. J Immunol 2005 1.16
14 Interplay and effects of temporal changes in the phosphorylation state of serine-302, -307, and -318 of insulin receptor substrate-1 on insulin action in skeletal muscle cells. Mol Endocrinol 2008 1.12
15 Cathepsin D is present in human eccrine sweat and involved in the postsecretory processing of the antimicrobial peptide DCD-1L. J Biol Chem 2005 1.12
16 Human alpha-defensins HNPs-1, -2, and -3 in renal cell carcinoma: influences on tumor cell proliferation. Am J Pathol 2002 1.10
17 The mesenchymal stem cell antigen MSCA-1 is identical to tissue non-specific alkaline phosphatase. Stem Cells Dev 2010 1.09
18 A peptide-gated ion channel from the freshwater polyp Hydra. J Biol Chem 2007 1.08
19 Specific role for cathepsin S in the generation of antigenic peptides in vivo. Eur J Immunol 2002 1.07
20 Cathepsin E: a mini review. Biochem Biophys Res Commun 2008 1.06
21 Three homologous subunits form a high affinity peptide-gated ion channel in Hydra. J Biol Chem 2010 1.05
22 DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype. Proc Natl Acad Sci U S A 2006 1.04
23 Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange. Eur J Immunol 2010 1.04
24 Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes. J Immunol 2004 1.01
25 Generation of multiple stable dermcidin-derived antimicrobial peptides in sweat of different body sites. J Invest Dermatol 2006 0.99
26 Roles of the Mdm10, Tom7, Mdm12, and Mmm1 proteins in the assembly of mitochondrial outer membrane proteins in Neurospora crassa. Mol Biol Cell 2010 0.97
27 OPA1, the disease gene for autosomal dominant optic atrophy, is specifically expressed in ganglion cells and intrinsic neurons of the retina. Invest Ophthalmol Vis Sci 2004 0.96
28 The heat shock protein Hsp70 enhances antigen-specific proliferation of human CD4+ memory T cells. Eur J Immunol 2005 0.96
29 FOXO3 is a glucocorticoid receptor target and regulates LKB1 and its own expression based on cellular AMP levels via a positive autoregulatory loop. PLoS One 2012 0.95
30 NMR analysis of KChIP4a reveals structural basis for control of surface expression of Kv4 channel complexes. J Biol Chem 2008 0.94
31 Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner. J Leukoc Biol 2004 0.94
32 Chondrocyte secreted CRTAC1: a glycosylated extracellular matrix molecule of human articular cartilage. Matrix Biol 2006 0.94
33 Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat. J Biol Chem 2012 0.94
34 Cathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblasts. Haematologica 2010 0.94
35 Cathepsin S dominates autoantigen processing in human thymic dendritic cells. J Autoimmun 2012 0.94
36 Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus. Antimicrob Agents Chemother 2009 0.92
37 Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells. J Biol Chem 2008 0.92
38 Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19. J Biol Chem 2010 0.92
39 Quantifying cathepsin S activity in antigen presenting cells using a novel specific substrate. J Biol Chem 2008 0.91
40 A novel cell penetrating aspartic protease inhibitor blocks processing and presentation of tetanus toxoid more efficiently than pepstatin A. Biochem Biophys Res Commun 2007 0.91
41 Cathepsin S activity is detectable in human keratinocytes and is selectively upregulated upon stimulation with interferon-gamma. J Invest Dermatol 2002 0.91
42 Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells. J Immunol 2005 0.91
43 Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators. J Med Chem 2005 0.90
44 A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles. FEBS J 2007 0.90
45 Prospective isolation of mesenchymal stem cells from human bone marrow using novel antibodies directed against Sushi domain containing 2. Stem Cells Dev 2013 0.90
46 Pharmacokinetics and safety of intravitreally delivered etanercept. Graefes Arch Clin Exp Ophthalmol 2004 0.89
47 Development of a novel fluorescent substrate for Autolysin E, a bacterial type II amidase. Biochem Biophys Res Commun 2009 0.89
48 Muropeptide modification-amidation of peptidoglycan D-glutamate does not affect the proinflammatory activity of Staphylococcus aureus. Infect Immun 2007 0.89
49 Alterations of amino acids and glutamate transport in the DBA/2J mouse retina; possible clues to degeneration. Graefes Arch Clin Exp Ophthalmol 2007 0.89
50 The transporter associated with antigen processing (TAP) is active in a post-ER compartment. J Cell Sci 2010 0.89
51 Resistance against antimicrobial peptides is independent of Escherichia coli AcrAB, Pseudomonas aeruginosa MexAB and Staphylococcus aureus NorA efflux pumps. Int J Antimicrob Agents 2008 0.88
52 Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages. Biol Chem 2002 0.87
53 alpha B-crystallin is a cytoplasmic interaction partner of the kidney-specific cadherin-16. J Mol Biol 2008 0.87
54 Increased in vivo frequency of IA-2 peptide-reactive IFNgamma+/IL-4- T cells in type 1 diabetic subjects. J Autoimmun 2004 0.87
55 Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels. J Gen Virol 2008 0.87
56 Detection of dermcidin-derived peptides in sweat by ProteinChip technology. J Immunol Methods 2002 0.87
57 Expansion of peripheral CD8+ CD28- T cells in response to Epstein-Barr virus in patients with rheumatoid arthritis. J Rheumatol 2005 0.87
58 Biomimetic macroporous PEG hydrogels as 3D scaffolds for the multiplication of human hematopoietic stem and progenitor cells. Biomaterials 2013 0.87
59 Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins. Cell Physiol Biochem 2007 0.87
60 Glutathione-conjugated sulfanylalkanols are substrates for ABCC11 and γ-glutamyl transferase 1: a potential new pathway for the formation of odorant precursors in the apocrine sweat gland. Exp Dermatol 2014 0.86
61 Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4+ memory T cells. Eur J Immunol 2010 0.86
62 70-kDa heat shock proteins: specific interactions with HLA-DR molecules and their peptide fragments. Eur J Immunol 2007 0.86
63 A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway. Chembiochem 2006 0.85
64 Induction of autoimmunity by expansion of autoreactive CD4+CD62Llow cells in vivo. J Immunol 2006 0.84
65 Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain. Biol Chem 2006 0.84
66 Human gastric TFF2 peptide contains an N-linked fucosylated N,N'-diacetyllactosediamine (LacdiNAc) oligosaccharide. Glycobiology 2012 0.84
67 Cathepsin E regulates the presentation of tetanus toxin C-fragment in PMA activated primary human B cells. Biochem Biophys Res Commun 2008 0.84
68 Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins. J Leukoc Biol 2007 0.84
69 Proteomic exploitation on prothymosin alpha-induced mononuclear cell activation. Proteomics 2007 0.83
70 Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells. Eur J Immunol 2002 0.83
71 Cadherin-9 is a novel cell surface marker for the heterogeneous pool of renal fibroblasts. PLoS One 2007 0.83
72 AE37 peptide vaccination in prostate cancer: a 4-year immunological assessment updates on a phase I trial. Cancer Immunol Immunother 2013 0.82
73 Characterization of legumain. Biol Chem 2002 0.82
74 Common cellular and diverse genetic basis of thymoma-associated myasthenia gravis: role of MHC class II and AIRE genes and genetic polymorphisms. Ann N Y Acad Sci 2008 0.82
75 Prothymosin alpha immunoactive carboxyl-terminal peptide TKKQKTDEDD stimulates lymphocyte reactions, induces dendritic cell maturation and adopts a beta-sheet conformation in a sequence-specific manner. Mol Immunol 2008 0.81
76 Regulation of cathepsin G reduces the activation of proinsulin-reactive T cells from type 1 diabetes patients. PLoS One 2011 0.81
77 Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases. Bioorg Med Chem Lett 2004 0.81
78 Mutations in the substrate binding site of human heat-shock protein 70 indicate specific interaction with HLA-DR outside the peptide binding groove. Immunology 2014 0.80
79 A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation. J Invest Dermatol 2012 0.80
80 Estrogen and the inner ear: megalin knockout mice suffer progressive hearing loss. FASEB J 2007 0.80
81 A periodate-cleavable linker for functional proteomics under slightly acidic conditions: application for the analysis of intracellular aspartic proteases. J Proteome Res 2012 0.80
82 Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro. Immunology 2007 0.80
83 Comparative analysis of the human and chicken prion protein copper binding regions at pH 6.5. J Biol Chem 2005 0.79
84 Processing of laminin α chains generates peptides involved in wound healing and host defense. J Innate Immun 2014 0.79
85 Th2 dominance of T helper cell response to preproinsulin in individuals with preclinical type 1 diabetes. Ann N Y Acad Sci 2002 0.79
86 Processing of CXCL12 by different osteoblast-secreted cathepsins. Stem Cells Dev 2012 0.79
87 Development and precise characterization of phospho-site-specific antibody of Ser(357) of IRS-1: elimination of cross reactivity with adjacent Ser(358). Biochem Biophys Res Commun 2008 0.79
88 Protease-resistant human GAD-derived altered peptide ligands decrease TNF-alpha and IL-17 production in peripheral blood cells from patients with type 1 diabetes mellitus. Mol Immunol 2009 0.79
89 T cell epitope definition by differential mass spectrometry: identification of a novel, immunogenic HLA-B8 ligand directly from renal cancer tissue. Proteomics 2006 0.79
90 Monoclonal antibodies to discriminate the EF hand containing calcium binding adaptor proteins EFhd1 and EFhd2. Monoclon Antib Immunodiagn Immunother 2013 0.78
91 Ramoplanin imaging conjugates--synthesis and evaluation. Med Chem 2014 0.78
92 Recombinant cathepsin E has no proteolytic activity at neutral pH. Biochem Biophys Res Commun 2007 0.78
93 Electrophysiological and molecular characterization of the inward rectifier in juxtaglomerular cells from rat kidney. J Physiol 2004 0.78
94 Relationship between T and B cell responses to proinsulin in human type 1 diabetes. Ann N Y Acad Sci 2003 0.78
95 Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis. Cell Tissue Res 2007 0.78
96 Prothymosin α and a prothymosin α-derived peptide enhance T(H)1-type immune responses against defined HER-2/neu epitopes. BMC Immunol 2013 0.78
97 A pilot study in prostate cancer patients treated with the AE37 Ii-key-HER-2/neu polypeptide vaccine suggests that HLA-A*24 and HLA-DRB1*11 alleles may be prognostic and predictive biomarkers for clinical benefit. Cancer Immunol Immunother 2015 0.77
98 Determinants for the cAMP-binding site at the S-adenosylhomocysteine-hydrolase. Naunyn Schmiedebergs Arch Pharmacol 2009 0.77
99 TFF1 is differentially expressed in stationary and migratory rat gastric epithelial cells (RGM-1) after in vitro wounding: influence of TFF1 RNA interference on cell migration. Cell Physiol Biochem 2013 0.77
100 Characterization of the endopeptidase activity of tripeptidyl-peptidase II. Biochem Biophys Res Commun 2012 0.76
101 Development of an ELISA for the quantification of the C-terminal decapeptide prothymosin α(100-109) in sera of mice infected with bacteria. J Immunol Methods 2013 0.76
102 Development of a fluorescence resonance energy transfer peptide library technology for detection of protease contaminants in protein-based raw materials used in diagnostic assays. Assay Drug Dev Technol 2011 0.76
103 Tff3 is expressed in neurons and microglial cells. Cell Physiol Biochem 2014 0.76
104 Differential modulation of CNS-specific effector and regulatory T cells during tolerance induction by recombinant invariant chains in vivo. Brain Behav Immun 2009 0.76
105 Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease. Neurogenetics 2010 0.76
106 Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions. Biochem Pharmacol 2007 0.76
107 Potential of the gastric motility drug lorglumide in prostate cancer imaging. Eur J Pharm Sci 2011 0.76
108 A postcolumn alkalinization procedure enhances the sensitivity of fluorescence detection of fluorescein-labeled substances in RP-HPLC. Anal Biochem 2005 0.76
109 Cathepsin A is expressed in primary human antigen-presenting cells. Immunol Lett 2009 0.76
110 Imaging of human glioma cells by means of a Syndecan-4 directed DOTA-conjugate. Amino Acids 2009 0.75
111 Susceptibility of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect 2011 0.75
112 Differential activity of innate defense antimicrobial peptides against Nocardia species. BMC Microbiol 2010 0.75
113 Peptides derived from the human laminin alpha4 and alpha5 chains exhibit antimicrobial activity. Peptides 2010 0.75
114 Possible association of non-binding of HSP70 to HLA-DRB1 peptide sequences and protection from rheumatoid arthritis. Immunogenetics 2002 0.75
115 A proinsulin 74-90-derived protease-resistant, altered peptide ligand increases TGF-beta 1 secretion in PBMC from patients with type 1 diabetes mellitus. J Leukoc Biol 2010 0.75
116 Effects of gum arabic (Acacia senegal) on water and electrolyte balance in healthy mice. J Ren Nutr 2008 0.75
117 Fluorescein-labeled Bacitracin and Daptomycin Conjugates: Synthesis, Fluorescence Imaging and Evaluation. Med Chem 2016 0.75
118 Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway. EMBO Rep 2017 0.75
119 Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells. Invest New Drugs 2012 0.75
120 Fluorescence imaging of human cells with a novel conjugate of the antifungal nystatin. Med Chem 2014 0.75
121 Cell nucleus directed 2,3,5-triiodobenzoic acid conjugates. Med Chem 2009 0.75
122 Corrigendum: Human commensals producing a novel antibiotic impair pathogen colonization. Nature 2016 0.75
123 Complexes of an alpha thymosin derivative with ¹⁸⁵/¹⁸⁷Re and (⁹⁹m)Tc: structural analysis and initial biological evaluation. Chem Biol Drug Des 2012 0.75