PubRank

S F Lowry

Author PubWeight™ 207.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Shock and tissue injury induced by recombinant human cachectin. Science 1986 16.24
2 Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1988 13.42
3 Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group. N Engl J Med 1996 5.25
4 Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J Exp Med 1988 5.16
5 Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group. Crit Care Med 1997 4.86
6 Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia. J Exp Med 1989 4.66
7 Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog. Surg Gynecol Obstet 1987 4.18
8 Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proc Natl Acad Sci U S A 1992 3.61
9 An overview of mortality risk prediction in sepsis. Crit Care Med 1995 3.37
10 Cytokine appearance in human endotoxemia and primate bacteremia. Surg Gynecol Obstet 1988 3.30
11 Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia. J Infect Dis 1997 2.39
12 The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans. J Clin Invest 1990 2.08
13 IL-8 in septic shock, endotoxemia, and after IL-1 administration. J Immunol 1991 2.03
14 Inflammatory cytokines and cell response in surgery. Surgery 2000 2.02
15 Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. J Clin Invest 1996 1.99
16 Endogenous IL-10 protects mice from death during septic peritonitis. J Immunol 1995 1.94
17 Cachectin: a hormone that triggers acute shock and chronic cachexia. J Infect Dis 1988 1.94
18 Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J Infect Dis 1996 1.88
19 Anticachectin/tumor necrosis factor-alpha antibodies attenuate development of cachexia in tumor models. FASEB J 1989 1.82
20 Total parenteral nutrition and bowel rest modify the metabolic response to endotoxin in humans. Ann Surg 1989 1.79
21 Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J Immunol 1993 1.73
22 Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13. J Infect Dis 1997 1.63
23 Tumor necrosis factor in the pathophysiology of infection and sepsis. Clin Immunol Immunopathol 1990 1.55
24 Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential. J Exp Med 1986 1.49
25 Interleukin 1 receptor blockade attenuates the host inflammatory response. Proc Natl Acad Sci U S A 1990 1.47
26 Effects of intravenous IL-8 administration in nonhuman primates. J Immunol 1992 1.44
27 Correlation between Acute Physiology and Chronic Health Evaluation (APACHE) III score and immunological parameters in critically ill patients with sepsis. Br J Surg 1996 1.41
28 The role of cytokine mediators in septic shock. Adv Surg 1990 1.40
29 Cachexia and the acute-phase protein response in inflammation are regulated by interleukin-6. Eur J Immunol 1993 1.39
30 Cachetin/TNF-alpha in septic shock and septic adult respiratory distress syndrome. Am Rev Respir Dis 1988 1.38
31 Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense? Shock 1995 1.32
32 The biologic characteristics of cytokines and their implication in surgical injury. Surg Gynecol Obstet 1990 1.32
33 Passive immunization against tumor necrosis factor-alpha impairs host defense during pneumococcal pneumonia in mice. Am J Respir Crit Care Med 1997 1.29
34 Peripheral blood leukocyte kinetics following in vivo lipopolysaccharide (LPS) administration to normal human subjects. Influence of elicited hormones and cytokines. Ann Surg 1989 1.27
35 Isolated aneurysms of the iliac artery. Arch Surg 1978 1.24
36 Essential fatty acid deficiency in total parenteral nutrition: time course of development and suggestions for therapy. Surgery 1978 1.21
37 Mobilization of potent plasma bactericidal activity during systemic bacterial challenge. Role of group IIA phospholipase A2. J Clin Invest 1998 1.15
38 Effect of hypertriglyceridemia on endotoxin responsiveness in humans. Infect Immun 1995 1.15
39 Modeling endotoxin-induced systemic inflammation using an indirect response approach. Math Biosci 2008 1.13
40 Epinephrine inhibits endotoxin-induced IL-1 beta production: roles of tumor necrosis factor-alpha and IL-10. Am J Physiol 1997 1.12
41 Nicotine exposure alters in vivo human responses to endotoxin. Clin Exp Immunol 2007 1.11
42 Elevation of IL-18 in human sepsis. J Clin Immunol 2000 1.09
43 Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis. Arch Surg 1994 1.09
44 Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease. Blood 1992 1.07
45 Down-regulation of surface receptors for TNF and IL-1 on circulating monocytes and granulocytes during human endotoxemia: effect of neutralization of endotoxin-induced TNF activity by infusion of a recombinant dimeric TNF receptor. J Immunol 1997 1.07
46 Effects of IL-10 on systemic inflammatory responses during sublethal primate endotoxemia. J Immunol 1997 1.06
47 Cancer cachexia and protein metabolism. Lancet 1984 1.05
48 Tolerance to endotoxin prevents mortality in infected thermal injury: association with attenuated cytokine responses. J Infect Dis 1992 1.02
49 One hundred and fourteen fistulas of the gastrointestinal tract treated with total parenteral nutrition. Surg Gynecol Obstet 1986 1.01
50 Cachectin/TNF production in experimental burns and Pseudomonas infection. Arch Surg 1988 1.01
51 In vivo effects of the antiglucocorticoid RU 486 on glucocorticoid and cytokine responses to Escherichia coli endotoxin. Infect Immun 1992 1.00
52 Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin. J Infect Dis 1996 0.98
53 Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans. Blood 1997 0.97
54 Bacterial overgrowth and intestinal atrophy in the etiology of gut barrier failure in the rat. Am J Surg 1991 0.96
55 Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia--a clinical research center study. J Clin Endocrinol Metab 1996 0.96
56 Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia. Crit Care Med 2000 0.96
57 Role of interleukin-1 and the therapeutic potential of interleukin-1 receptor antagonist in sepsis. Circ Shock 1994 0.95
58 Recombinant human growth hormone enhances the metabolic efficacy of parenteral nutrition: a double-blind, randomized controlled study. J Clin Endocrinol Metab 1992 0.95
59 Endotoxin induces downregulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans. Blood 1995 0.94
60 Influence of IL-1 receptor blockade on the human response to endotoxemia. J Immunol 1995 0.94
61 Protection against lethal Escherichia coli bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081. J Immunol 1996 0.94
62 Catecholamines increase monocyte TNF receptors and inhibit TNF through beta 2-adrenoreceptor activation. Am J Physiol 1997 0.93
63 Persistently elevated soluble tumor necrosis factor receptor and interleukin-1 receptor antagonist levels in critically ill patients. J Am Coll Surg 1994 0.93
64 Tumor necrosis factor-enhanced leukotriene B4 generation and chemotaxis in human neutrophils. Arch Surg 1988 0.93
65 Anti-endotoxin therapy in primate bacteremia with HA-1A and BPI. Ann Surg 1994 0.93
66 Harry M. Vars award. Glutamine or fiber supplementation of a defined formula diet: impact on bacterial translocation, tissue composition, and response to endotoxin. JPEN J Parenter Enteral Nutr 1990 0.93
67 Biologic control of injury and inflammation: much more than too little or too late. World J Surg 1996 0.93
68 Lipopolysaccharide-induced interleukin 8 production by human whole blood is enhanced by epinephrine and inhibited by hydrocortisone. Infect Immun 1997 0.93
69 Physiological responses to cachectin. Ciba Found Symp 1987 0.92
70 Epinephrine exerts anticoagulant effects during human endotoxemia. J Exp Med 1997 0.92
71 Interleukin-1 alpha and tumor necrosis factor alpha cause placental injury in the rat. Am J Pathol 1989 0.91
72 Extremity amino acid metabolism during starvation and intravenous refeeding in humans. Am J Physiol 1986 0.90
73 Interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF alpha) regulate insulin-like growth factor binding protein-1 (IGFBP-1) levels and mRNA abundance in vivo and in vitro. Horm Metab Res 1999 0.90
74 Hepatocellular membrane function during chronic burn injury. J Surg Res 1989 0.90
75 Contribution of interleukin-1 to activation of coagulation and fibrinolysis, neutrophil degranulation, and the release of secretory-type phospholipase A2 in sepsis: studies in nonhuman primates after interleukin-1 alpha administration and during lethal bacteremia. Blood 1995 0.90
76 Protean manifestations of neonatal hyperinsulinism. Ann Surg 1981 0.89
77 Expression of tumour necrosis factor receptor and Toll-like receptor 2 and 4 on peripheral blood leucocytes of human volunteers after endotoxin challenge: a comparison of flow cytometric light scatter and immunofluorescence gating. Clin Exp Immunol 2005 0.89
78 Cancer cachexia and the rate of whole body lipolysis in man. Metabolism 1986 0.89
79 A human tumor necrosis factor p75 receptor agonist stimulates in vitro T cell proliferation but does not produce inflammation or shock in the baboon. J Exp Med 1996 0.88
80 Increased neutrophil mobilization and decreased chemotaxis during cortisol and epinephrine infusions. J Trauma 1991 0.88
81 Endogenous cachectin/tumour necrosis factor-alpha production contributes to experimental cancer-associated cachexia. Cancer Surv 1989 0.87
82 Interleukin-1 blockade attenuates mediator release and dysregulation of the hemostatic mechanism during human sepsis. Arch Surg 1995 0.87
83 Comparison of numerical and phenotypic leukocyte changes during constant hydrocortisone infusion in normal humans with those in thermally injured patients. Surg Gynecol Obstet 1987 0.87
84 The effect of total parenteral nutrition on chemotherapy-induced myelosuppression. A randomized study. Am J Med 1983 0.87
85 Identification of a novel tumor necrosis factor alpha/cachectin from the livers of burned and infected rats. Arch Surg 1990 0.87
86 Cachectin/TNF mediates the pathophysiological effects of bacterial endotoxin/lipopolysaccharide (LPS). Prog Clin Biol Res 1988 0.86
87 Cachectin: its impact on metabolism and nutritional status. Annu Rev Nutr 1988 0.86
88 Impact of exogenous growth hormone on host preservation and tumor cell-cycle distribution in a rat sarcoma model. J Surg Res 1991 0.86
89 Tracer priming in human protein turnover studies with [15N]glycine. Biochem Med 1985 0.86
90 Epinephrine attenuates down-regulation of monocyte tumor necrosis factor receptors during human endotoxemia. J Leukoc Biol 1997 0.86
91 Cachectin: a pluripotent hormone released during the host response to invasion. Recent Prog Horm Res 1987 0.85
92 The role of cytokines in cancer cachexia. JPEN J Parenter Enteral Nutr 1993 0.85
93 Translational potential of systems-based models of inflammation. Clin Transl Sci 2009 0.84
94 Metabolic alterations in a noncachectic animal tumor system. Cancer 1981 0.84
95 Parenteral nutrition facilitates activation of coagulation but not of fibrinolysis during human endotoxemia. J Infect Dis 1998 0.84
96 PEG-BP-30 monotherapy attenuates the cytokine-mediated inflammatory cascade in baboon Escherichia coli septic shock. J Surg Res 1995 0.83
97 The influence of human endotoxemia on CD95-induced apoptosis. Arch Surg 1998 0.83
98 Insulin-like growth factor-1 activity is inhibited by interleukin-1 alpha, tumor necrosis factor-alpha, and interleukin-6. Lymphokine Cytokine Res 1993 0.83
99 Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings. Surgery 1995 0.83
100 The metabolic effects of platelet-activating factor antagonism in endotoxemic man. Arch Surg 1994 0.82
101 Comparison of peripheral blood leukocyte kinetics after live Escherichia coli, endotoxin, or interleukin-1 alpha administration. Studies using a novel interleukin-1 receptor antagonist. Ann Surg 1993 0.82
102 Parenteral vitamin requirements during intravenous feeding. Am J Clin Nutr 1978 0.82
103 Zinc and copper replacement during total parenteral nutrition. Am J Clin Nutr 1981 0.82
104 Fat emulsion infusion potentiates coagulation activation during human endotoxemia. Thromb Haemost 1996 0.82
105 The role of house staff in undergraduate surgical education. Surgery 1976 0.82
106 Nutritional support and cancer cachexia. Evolving concepts of mechanisms and adjunctive therapies. Hematol Oncol Clin North Am 1991 0.82
107 Influence of increasing dietary intake on whole body protein kinetics in normal man. Clin Nutr 1986 0.82
108 Influence of hypercortisolemia on the acute-phase protein response to endotoxin in humans. Surgery 1992 0.82
109 Influence of substrate background on peripheral tissue responses to growth hormone. J Surg Res 1988 0.82
110 Protein and substrate metabolism during starvation and parenteral refeeding. Clin Sci (Lond) 1988 0.81
111 Whole body and splanchnic leucine, phenylalanine, and glucose kinetics during endotoxemia in humans. Am J Physiol 1994 0.81
112 Whole-body protein breakdown and 3-methylhistidine excretion during brief fasting, starvation, and intravenous repletion in man. Ann Surg 1985 0.81
113 Tumor necrosis factor-alpha. J Surg Res 1991 0.81
114 Cachectin/tumor necrosis factor production by fetal and newborn rat hepatic macrophages. J Pediatr Surg 1989 0.81
115 Skeletal muscle amino acid and myofibrillar protein mRNA response to thermal injury and infection. Am J Physiol 1991 0.80
116 Inflammatory cytokines in major surgery: a functional perspective. Intensive Care Med 1999 0.80
117 Topical effects of 16,16 dimethyl prostaglandin E2 on gastric acid secretion and mucosal permeability to hydrogen ions in dogs. Gut 1978 0.80
118 Parenteral nutrition and liver dysfunction--new insight? JPEN J Parenter Enteral Nutr 1995 0.80
119 Monocyte tumor necrosis factor receptor levels as a predictor of risk in human sepsis. Arch Surg 1996 0.80
120 Tumour location influences local cytokine production and host metabolism. Surg Oncol 1992 0.80
121 The pathophysiologic role of cachectin/TNF in septic shock and cachexia. Ann Inst Pasteur Immunol 1988 0.80
122 Appearance of hybridoma growth factor/interleukin-6 in the serum of mice bearing a methylcholanthrene-induced sarcoma. Biochem Biophys Res Commun 1988 0.80
123 Interleukin-1 receptor blockade does not affect endotoxin-induced changes in plasma thyroid hormone and thyrotropin concentrations in man. J Clin Endocrinol Metab 1995 0.80
124 Submaximal exercise during intravenous hyperalimentation of depleted subjects. Ann Surg 1988 0.80
125 Nutritional manipulations and tumor growth. I. The effects of starvation. Am J Clin Nutr 1979 0.79
126 Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans. Proc Natl Acad Sci U S A 1989 0.79
127 Vitamin requirements of intravenously fed man. J Environ Pathol Toxicol Oncol 1985 0.79
128 Interleukin 1 binding to its type I, but not type II receptor, modulates the in vivo acute phase response. Cytokine 1995 0.79
129 Cancer cachexia revisited: old problems and new perspectives. Eur J Cancer 1991 0.79
130 Insulin-like growth factor I preserves host lean tissue mass in cancer cachexia. Am J Physiol 1992 0.79
131 Glucose disposal and gluconeogenesis from alanine in tumor-bearing Fischer 344 rats. J Natl Cancer Inst 1981 0.79
132 Tumor necrosis factor-alpha induces activation of coagulation and fibrinolysis in baboons through an exclusive effect on the p55 receptor. Blood 1996 0.79
133 Effect of work-induced hypertrophy on skeletal muscle of tumor- and nontumor-bearing rats. J Appl Physiol Respir Environ Exerc Physiol 1979 0.78
134 A prospective, randomized study of adjuvant parenteral nutrition in the treatment of sarcomas: results of metabolic and survival studies. Surgery 1984 0.78
135 Abnormalities of zinc and copper during total parenteral nutrition. Ann Surg 1979 0.78
136 Determine whether 1 week of total parenteral nutrition (TPN) in healthy subjects alters systemic responses to a subsequent dose of endotoxin. Ann Surg 1996 0.78
137 Cachetin/TNF: a macrophage protein that induces cachexia and shock. JPEN J Parenter Enteral Nutr 1989 0.78
138 Neutralization of TNF does not influence endotoxininduced changes in thyroid hormone metabolism in humans. Am J Physiol 1999 0.78
139 The influence of substrate background on the acute metabolic response to epinephrine and cortisol. J Trauma 1991 0.78
140 The effect of starvation and total parenteral nutrition on skeletal muscle amino acid content and membrane potential difference in normal man. Surg Gynecol Obstet 1988 0.78
141 Parenteral nutrition alters monocyte TNF receptor activity. J Surg Res 1995 0.78
142 Nutritional manipulations and tumor growth. II. The effects of intravenous feeding. Am J Clin Nutr 1979 0.78
143 Effect of chronic protein malnutrition on host-tumor composition and growth. J Surg Res 1979 0.77
144 Effect of combined cortisol-endotoxin administration on peripheral blood leukocyte counts and phenotype in normal humans. Arch Surg 1992 0.77
145 Glucose turnover and gluconeogenesis during hypocaloric glucose infusion in tumor-bearing F344 male rats. J Natl Cancer Inst 1980 0.77
146 Multivariate analysis of 9 disease-associated variables for outcome prediction in patients with sepsis. Arch Surg 1998 0.77
147 Nutritional modulation of immunity and the inflammatory response. Nutrition 1998 0.77
148 Canine gastric blood flow and oxygen consumption during cimetidine inhibition of acid secretion. Surg Forum 1976 0.77
149 Influence of nutritional status on exertion-induced forearm amino acid metabolism in normal man. J Surg Res 1984 0.77
150 Total parenteral nutrition in patients with insulin-requiring diabetes mellitus. J Am Coll Nutr 1986 0.76
151 Effects of intra-arterial infusion of prostaglandin E1 on gastric secretion and blood flow. Surgery 1978 0.76
152 Deep venous thromboembolism in patients undergoing inguinal lymph node dissection for melanoma. Ann Surg 1981 0.76
153 Oxygen consumption during cimetidine and prostaglandin E2 inhibition of acid secretion. Am J Physiol 1978 0.76
154 Effect of total parenteral nutrition on whole body protein kinetics in cachectic patients with benign or malignant disease. JPEN J Parenter Enteral Nutr 1988 0.75
155 Selectin neutralization: does it make biological sense? Crit Care Med 1999 0.75
156 Back to the future: is lipid A an appropriate target for the therapy of sepsis? Crit Care Med 2000 0.75
157 Efficacy of nutritional pharmacology in surgical patients. Curr Opin Clin Nutr Metab Care 1998 0.75
158 Effect of starvation and total parenteral nutrition on electrolyte homeostasis in normal man. JPEN J Parenter Enteral Nutr 1988 0.75
159 The response of fibronectin to differing parenteral caloric sources in normal man. JPEN J Parenter Enteral Nutr 1985 0.75
160 Effect of hormonal and substrate backgrounds on cell membrane function in normal males. J Appl Physiol (1985) 1987 0.75
161 Preservation of functional aerobic capacity with daily submaximal exercise during intravenous feeding in hospitalized normal man. World J Surg 1988 0.75
162 Nutrition support and the wave of the future. Nutr Clin Pract 1989 0.75
163 Influence of enterectomy on peripheral tissue glutamine efflux in critically ill patients. Surgery 1990 0.75
164 Effect of protein malnutrition on host-tumor composition and growth. Surg Forum 1977 0.75
165 Low plasma carnitine in patients on prolonged total parenteral nutrition: association with low plasma lysine. JPEN J Parenter Enteral Nutr 1990 0.75
166 Body weight change and nutritional adequacy in the parenterally alimented rat. J Surg Res 1978 0.75
167 Orotic acid excretion during starvation and refeeding in normal men. Metabolism 1985 0.75
168 Nutrition in burn patients. Semin Nephrol 1993 0.75
169 Body protein kinetics during perioperative intravenous nutritional support. Surg Gynecol Obstet 1986 0.75
170 Effect of the route of nutrient administration on whole-body protein kinetics in man. Metabolism 1987 0.75
171 Starvation leads to decreased levels of mRNA for myofibrillar proteins. J Surg Res 1989 0.75
172 Interleukin-1 contributes to increased concentrations of soluble tumor necrosis factor receptor type I in sepsis. J Infect Dis 1995 0.75
173 Local effects of 16, 16-dimethyl prostaglandin E2 on gastric blood flow and acid secretion. Surgery 1981 0.75
174 Effect of prostaglandin E in multiple experimental models. IV. Effect on resistance to endotoxin and tumor necrosis factor shock. J Surg Res 1990 0.75
175 The effect of interleukin-1 alpha and tumor necrosis factor alpha on the secretion of human chorionic gonadotropin by JAR human choriocarcinoma cells. Biochem Biophys Res Commun 1989 0.75
176 Experimental and clinical applications of molecular cell biology in nutrition and metabolism. JPEN J Parenter Enteral Nutr 1992 0.75
177 Peripheral tissue metabolism in man with varied disease states and similar weight loss. J Surg Res 1986 0.75
178 Preservation of functional aerobic capacity with daily submaximal exercise during intravenous feeding in hospitalized normal man. World J Surg 1988 0.75
179 Intravenous refeeding blocks growth hormone (GH)-provoked rises in serum free fatty acids and blunting of somatotroph response to GH-releasing hormone in normal men. J Clin Endocrinol Metab 1989 0.75
180 Exercise-mediated peripheral tissue and whole-body amino acid metabolism during intravenous feeding in normal man. Clin Sci (Lond) 1989 0.75
181 The effects of glucocorticoid therapy on inflammatory responses to coronary artery bypass graft surgery. Arch Surg 2001 0.75
182 Glucose turnover and gluconeogenesis in a patient with somatostatinoma. Surgery 1981 0.75
183 Pretreatment with a 55-kDa tumor necrosis factor receptor-immunoglobulin fusion protein attenuates activation of coagulation, but not of fibrinolysis, during lethal bacteremia in baboons. J Infect Dis 1997 0.75
184 Thermogenic and nitrogen response to submaximal exercise in parenterally repleted normal man. Am J Clin Nutr 1987 0.75
185 Hormonal regulation of protein metabolism. JPEN J Parenter Enteral Nutr 1991 0.75