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O Mäkelä

Author PubWeight™ 138.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Recent primary toxoplasma infection indicated by a low avidity of specific IgG. J Infect Dis 1989 3.67
2 Separation of normal and immune lymphoid cells by antigen-coated coated columns. Antigen-binding characteristics of membrane antibodies as analyzed by hapten-protein antigens. J Exp Med 1970 3.08
3 Effect of the number of haptens coupled to each erythrocyte on haemolytic plaque formation. Immunology 1969 2.71
4 The role of cell number and source in adoptive immunity. Immunology 1965 2.68
5 The effect of antigen dosage on the response of adoptively transferred cells. Immunology 1965 2.59
6 Inherited immunoglobulin idiotypes of the mouse. Immunol Rev 1977 2.29
7 Comparison of a new tumour marker, CA 19-9, with alpha-fetoprotein and carcinoembryonic antigen in patients with upper gastrointestinal diseases. J Clin Pathol 1984 1.98
8 Evaluation of CA 19-9 as a serum tumour marker in pancreatic cancer. Br J Cancer 1986 1.91
9 Soluble antigen-antibody complexes and platelet aggregation. Acta Pathol Microbiol Scand 1969 1.91
10 Inheritance of antibody specificity. I. Anti-(4-hydroxy-3-nitrophenyl)acetyl of the mouse primary response. J Exp Med 1974 1.82
11 Strain differences in the fine specificity of mouse anti-hapten antibodies. Eur J Immunol 1973 1.69
12 Isolated hapten-binding receptors of sensitized lymphocytes. I. Receptors from nylon wool-enriched mouse T lymphocytes lack serological markers of immunoglobulin constant domains but express heavy chain variable portions. Eur J Immunol 1977 1.61
13 Comparison of CA 19-9 and carcinoembryonic antigen (CEA) levels in the serum of patients with colorectal diseases. Br J Cancer 1984 1.56
14 The diversity and specialization of immunocytes. Prog Allergy 1970 1.54
15 Anti-oxazolone hybridomas and the structure of the oxazolone idiotype. J Immunol 1983 1.52
16 Assay of anti-hapten antibody with the aid of hapten-coupled bacteriophage. Immunology 1966 1.48
17 Isotype concentrations of human antibodies to Haemophilus influenzae type b polysaccharide (Hib) in young adults immunized with the polysaccharide as such or conjugated to a protein (diphtheria toxoid). J Immunol 1987 1.38
18 The four subclasses of IgG can be isolated from mouse serum by using Protein A-Sepharose. Scand J Immunol 1981 1.37
19 Determination of 19S and 7S components in an anti-hapten antibody. Ann Med Exp Biol Fenn 1967 1.34
20 Affinity requirements for antibody assays mapped by monoclonal antibodies. J Immunol 1983 1.33
21 Analogies between lymphocyte receptors and the resulting humoral antibodies. Transplant Rev 1970 1.29
22 A mendelian idiotype is demonstrable in the heteroclitic anti-NP antibodies of the mouse. Eur J Immunol 1978 1.29
23 Single lymph node cells producing heteroclitic bacteriophage antibody. J Immunol 1965 1.28
24 IgG subclasses of pneumococcal antibodies--effect of allotype G2m(n). Scand J Immunol 1989 1.26
25 The percentages of six immunoglobulin isotypes in human antibodies to tetanus toxoid: standardization of isotype-specific second antibodies in solid-phase assay. Eur J Immunol 1984 1.25
26 Cellular heterogeneity in the production of an anti-hapten antibody. J Exp Med 1967 1.22
27 Immunogenic properties of alpha (1----6) dextran, its protein conjugates, and conjugates of its breakdown products in mice. Scand J Immunol 1984 1.17
28 Haptenated bacteriophage in the assay of antibody quantity and affinity: maturation of an immune response. Immunochemistry 1970 1.14
29 Isotype concentrations of human antibodies to group A meningococcal polysaccharide. J Immunol 1986 1.12
30 Effect of the number of primed cells on the production of IgM and IgG antibodies in an adoptive secondary response. Int Arch Allergy Appl Immunol 1968 1.11
31 Human antibody responses to two conjugate vaccines of Haemophilus influenzae type B saccharides and diphtheria toxin. Scand J Immunol 1988 1.11
32 Antigenicity of dextran-protein conjugates in mice. Effect of molecular weight of the carbohydrate and comparison of two modes of coupling. J Immunol 1989 1.11
33 Proportions of Ig classes and subclasses in rubella antibodies. Scand J Immunol 1985 1.10
34 Genetics of mouse antibodies. II. Recombination between VH genes and allotype. Eur J Immunol 1975 1.10
35 IgG subclass distributions in anti-hapten and anti-polysaccharide antibodies induced by haptenated polysaccharides. Eur J Immunol 1983 1.10
36 Quantitation of human IgG subclass antibodies to Haemophilus influenzae type b capsular polysaccharide. Results of an international collaborative study using enzyme immunoassay methodology. J Immunol Methods 1992 1.09
37 Lack of heterogeneity in antihapten antibodies of a phylogenetically primitive shark. Nature 1980 1.07
38 Anti-hapten antibodies in normal sera. Eur J Immunol 1971 1.06
39 Selective inhibition of the secondary response of primed cells by incubation with hapten. Immunology 1968 1.06
40 Salmonella antigen 12-2: genetics of form variation. Ann Med Exp Biol Fenn 1966 1.02
41 Inheritance of antibody specificity. IV. Control of related molecular species by one VH gene. Cold Spring Harb Symp Quant Biol 1977 1.00
42 Concentrations of three hapten-binding immunoglobulins in pooled normal human serum. Eur J Immunol 1976 0.99
43 Affinity of IgM and IgG antibodies. Immunochemistry 1970 0.98
44 Establishment of anti-TNP antibody-producing human lymphoid lines by preselection for hapten binding followed by EBV transformation. Scand J Immunol 1979 0.98
45 Antibody responses in arthritic and uncomplicated Yersinia enterocolitica infections. J Clin Immunol 1985 0.98
46 Standard sera in solid-phase immunoassays. Eur J Immunol 1983 0.97
47 Modification of bacteriophage with hapten-epsilon-aminocaproyl-N-hydroxysuccinimide esters; increased sensitivity for immunoassay. Immunochemistry 1975 0.97
48 Immunological cross-reactions within a family of related haptens. Immunochemistry 1972 0.96
49 Extensive allelic sequence variation in the J region of the human immunoglobulin heavy chain gene locus. Eur J Immunol 1995 0.96
50 Isotype distribution and bactericidal activity of antibodies after immunization with Haemophilus influenzae type b vaccines at 18-24 months of age. J Infect Dis 1988 0.96
51 Establishment of specific antibody producing human lines by antigen preselection and Epstein-Barr virus (EBV)-transformation. J Clin Lab Immunol 1979 0.95
52 Isotypes of antibodies induced by plain dextran or a dextran-protein conjugate. Eur J Immunol 1985 0.94
53 Mouse Ig coded by VH families S107 or J606 bind to protein A. J Immunol 1990 0.94
54 Suppression or augmentation of the antihapten response in mice by antibodies of different specificities. J Exp Med 1973 0.94
55 Half-life of the maternal IgG1 allotype in infants. J Clin Immunol 1993 0.92
56 Adjuvant effect of bacterial LPS and/or alum precipitation in responses to polysaccharide and protein antigens. Immunology 1984 0.92
57 Allotype-associated differences in concentrations of human IgG subclasses. J Clin Immunol 1991 0.92
58 Maternal antibodies partly inhibit an active antibody response to routine tetanus toxoid immunization in infants. J Infect Dis 1992 0.91
59 The range and fine specificity of the anti-hapten immune response: phylogenetic studies. J Immunogenet 1982 0.90
60 Specifically cytotoxic human and mouse lymphoid cells induced with antibody or antigen-antibody complexes. J Immunol 1975 0.90
61 Carrier preimmunisation in the anti-hapten response of a marine fish. Nature 1975 0.90
62 Failure to demonstrate public idiotypes on cytolytic cells with specificity for NP-coupled syngeneic cells. Scand J Immunol 1980 0.89
63 The protective capacity of immune sera in experimental mouse salmonellosis is mainly due to IgM antibodies. Immunol Lett 1982 0.89
64 Antibody affinity in mice with the CBA/N defect. J Immunol 1980 0.89
65 Subtypes of human ABO blood groups and subtype-specific antibodies. J Immunol 1969 0.89
66 Immunoglobulin G subclass antibody responses in influenza A and parainfluenza type 1 virus infections. Clin Exp Immunol 1985 0.89
67 Oligomeric IgA: the major component of the in vitro primary response of mouse spleen fragments. J Exp Med 1973 0.89
68 Functional analogues of the VKOx1 gene in different strains of mice: evolutionary conservation but diversity based on V-J joining. J Immunol 1987 0.88
69 Mouse IgG antibodies have subclass associated affinity differences. Mol Immunol 1983 0.87
70 Several V genes participate in the early phenyloxazolone response in various combinations. Eur J Immunol 1986 0.87
71 'Allelic' forms of immunoglobulin V genes in different strains of mice. EMBO J 1989 0.86
72 Two types of antibody dependent cell-mediated cytotoxicity, arming and sensitization. J Immunol 1976 0.86
73 Fine-specificity of the immune response to oxazolone. I. Contact sensitivity and early antibodies. J Immunol 1981 0.86
74 Affinity and Ig classes of anti-hapten antibodies in carrier-preimmunized rats. Eur J Immunol 1973 0.86
75 Expression of an immunoglobulin VH gene in natural anti-hapten antibodies. Eur J Immunol 1975 0.86
76 Quantitation of immunoglobulin classes and subclasses in anti-Rh (D) antibodies. Vox Sang 1985 0.86
77 T-cell-deficient mice produce more antihapten antibodies against syngeneic than against allogeneic erythrocyte conjugates. J Exp Med 1976 0.85
78 IgA in blood and thoracic duct lymph: concentration and degree of polymerization. Scand J Immunol 1978 0.85
79 A gene of the immunoglobulin H-chain cluster controls the murine antibody response to pneumococcal polysaccharide type 14. Scand J Immunol 1980 0.85
80 Inheritance of antibody specificity. III. A new VH gene controls fine specificity of anti-p-azobenzenearsonate coupled to the carbon atom 5 of hydroxyphenylacetic acid in the mouse. J Exp Med 1976 0.85
81 The alternative binding site for protein A in the Fab fragment of immunoglobulins. Scand J Immunol 1993 0.85
82 Two str1cturally similar haptens each induce a different inherited idiotype. Eur J Immunol 1977 0.84
83 V genes of oxazolone antibodies in 10 strains of mice. Eur J Immunol 1991 0.84
84 Determination of homozygosity or heterozygosity for the G2m(n) allotype by a monoclonal, precipitating antibody. Exp Clin Immunogenet 1989 0.84
85 Effect of carrier preimmunization on the anti-hapten response in the chicken. Scand J Immunol 1974 0.84
86 Proportions of immunoglobulin isotypes in paralytic poliomyelitis and after vaccination. J Clin Immunol 1987 0.84
87 Isotype of protective anti-Salmonella antibodies in experimental mouse salmonellosis. Infect Immun 1984 0.84
88 One allele [G2m(n)] of the human IgG2 locus is more productive than the other. Eur J Immunol 1989 0.83
89 Effect of Gm allotypes on IgG2 antibody responses and IgG2 concentrations in children and adults. Int Immunol 1990 0.83
90 Fine specificity of the immune response to oxazolones III. Antibodies but not contact sensitivity specific for 2-furyloxazolone are controlled by an Igh-V gene in the mouse. Eur J Immunol 1983 0.83
91 Relative immunogenicity in mice of different regions of the human IgG. Scand J Immunol 1983 0.83
92 V genes of the primary antibody response of C57BL/10 mice to the hapten phenyloxazolone. Eur J Immunol 1988 0.82
93 Antibody response in Heterodontus. Mol Cell Biochem 1982 0.82
94 Reactivity of hybridoma antibodies with amniotic and plasma fibronectin. Scand J Immunol 1980 0.81
95 Clinical significance of ossification of the cartilages of the front feet based on nuclear bone scintigraphy, radiography and lameness examinations in 21 Finnhorses. Equine Vet J 2004 0.81
96 Crossing-over frequency in the Igh region of the mouse genome. Ann Immunol (Paris) 1984 0.81
97 Rabbit alpha-fetoprotein: normal levels and breakage tolerance with haptenated homologous alpha-fetoprotein. Eur J Immunol 1975 0.81
98 Spontaneous, augmentable cell-mediated cytotoxicity with limited target cell specificity in human blood. Eur J Immunol 1977 0.81
99 Establishment of specific antibody producing human lines by antigen preselection and EBV-transformation. Curr Top Microbiol Immunol 1978 0.81
100 Induction of aryl hydrocarbon hydroxylase activity and pulmonary carcinoma. Int J Cancer 1979 0.80
101 In vitro transformation of the Lewis blood groups of erythrocytes. Ann Med Exp Biol Fenn 1967 0.80
102 Monoclonal antibodies to carcinoembryonic antigen (CEA): characterization and use in a radioimmunoassay for CEA. Acta Pathol Microbiol Immunol Scand C 1982 0.80
103 Proportions of IgG subclasses in antibodies formed during vaccination with hepatitis B surface antigen. Scand J Immunol 1986 0.80
104 Studies of monoclonal and polyclonal anti-digoxin antibodies for serum digoxin radioimmunoassay. Scand J Clin Lab Invest 1981 0.80
105 Characterization of the early primary antibody response to the 4-hydroxy-3-iodo-5-nitrophenylactate (NIP) and the 2,4-dimitrophenyl (DNP) determinants. Immunology 1968 0.80
106 Correlations between the genetic control of natural and oxazolone-induced antibody production. Eur J Immunol 1978 0.79
107 Combinatorial association of V genes: one VH gene codes for three non-cross-reactive monoclonal antibodies each specific for a different antigen (phoxazolone, NP or gat). Mol Immunol 1988 0.79
108 A hapten-specific Ir gene. J Immunol 1979 0.79
109 Fine-specificity of the immune response to oxazolones. II. Cytolytic T cells. J Immunol 1981 0.79
110 Map position of Igh-Oxa gene within the Igh region of the DBA/2 mouse strain. J Immunol 1982 0.79
111 Lightly haptenated proteins induce IgM-deficient antibody responses. Eur J Immunol 1974 0.79
112 Reading of D genes in variable frames as a source of antibody diversity. Immunol Today 1985 0.79
113 Fine specificity and idiotypes of early antibodies against (4-hydroxy-3-nitrophenyl)acetyl (NP). J Immunol 1980 0.79
114 Timing of different virus neutralizing 19S and 7S antibodies in natural coxsackie infections of newborn babies and adults. Clin Exp Immunol 1968 0.78
115 LPS greatly enhances the antibody response to hapten-polysaccharide conjugates, but not to hapten-protein conjugates. Ann Immunol (Paris) 1983 0.78
116 Gm allotypes influence the production of IgG3 but the effect is age-dependent. Hum Immunol 1991 0.78
117 Low concentrations of Gm allotypic subsets G3 mg and G1 mf in homozygotes and heterozygotes. J Immunol 1993 0.78
118 Preferential production of IgA antibodies by spleen fragments immunized and maintained in vitro. Scand J Immunol 1981 0.78
119 Genetic control of the murine IgM plaque-forming cell response to type III pneumococcal polysaccharide. Scand J Immunol 1984 0.78
120 Fine-specificity of the contact sensitivity to 4-hydroxy-3-nitrophenyl acetyl (NP). J Immunol 1983 0.78
121 Salivary and serum antibodies in patients with Yersinia enterocolitica infection. Microb Pathog 1986 0.78
122 Complement and immunoglobulin levels in the serum and thoracic duct lymph of the rat. Eur J Immunol 1973 0.78
123 Hapten-carrier relationships in immunological unresponsiveness. Eur J Immunol 1971 0.78
124 Proportion of protein A bindable molecules in human IgM and IgA antibodies to seven antigens. Microb Pathog 1993 0.77
125 Quantitative representation of two germ-line V genes in the early antibody response to 2-phenyloxazolone. Eur J Immunol 1986 0.77
126 Assay of anti-oxazolone antibodies with the aid of oxazolone coupled bacteriophage. Immunochemistry 1971 0.77
127 V-region-mediated binding of human Ig by protein A. J Immunol 1993 0.76
128 The same few V genes account for a majority of oxazolone antibodies in most mouse strains. Mol Immunol 1992 0.76
129 Expression of a mouse immunoglobulin V gene in homozygote and heterozygotes. Ann Immunol (Paris) 1976 0.76
130 Expression of a mouse Ig V gene in antibodies of three immunoglobulin classes. Eur J Immunol 1975 0.76
131 Absence of carrier specificity in an adoptive secondary response. Immunology 1971 0.75
132 [The phylogenesis and ontogenesis of lymphatic tissue]. Duodecim 1970 0.75
133 Inherited chi chain polymorphism in mouse antibodies to phenyloxazolone. Eur J Immunol 1979 0.75
134 [Immunotherapy of cancer]. Duodecim 1973 0.75
135 [Immunological tolerance and autoimmunity]. Nord Med 1969 0.75
136 Spontaneous rosette formation with heavily haptenated sheep erythrocytes: a marker for mouse non-T lymphocytes. Scand J Immunol 1975 0.75
137 [Tumor immunology]. Duodecim 1969 0.75
138 Workshop report: how can immunology (except by tissue typing) improve the results of kidney transplantation. Scand J Urol Nephrol 1976 0.75
139 Evolutionary conservation of a gene which controls the VH regions of an anti-hapten antibody (NP). Ann Immunol (Paris) 1979 0.75
140 [Immunologic cancer therapy]. Duodecim 1967 0.75
141 [Immunology and medicine]. Duodecim 1968 0.75
142 [Immunological tolerance and autoimmunity]. Duodecim 1968 0.75
143 An immunoglobulin V gene polymorphism in the rat. Eur J Immunol 1982 0.75
144 Proportions of Ig classes and subclasses in mumps antibodies. Scand J Immunol 1985 0.75
145 [Principles of immune defects]. Duodecim 1985 0.75
146 Immune responses to hapten conjugates in vitro. Q Rev Biophys 1975 0.75
147 Immunoperoxidase staining of carcinoembryonic antigen with monoclonal antibodies in adenocarcinoma of the colon. Histochemistry 1982 0.75
148 Antibody-dependent cell-mediated cytotoxicity in various orders of vertebrates. Scand J Immunol 1977 0.75
149 [Is prolongation of newborn life always justified?]. Duodecim 1971 0.75
150 A specific anamnestic immune response induced by plant mitogens. Int Arch Allergy Appl Immunol 1969 0.75
151 Possible evolution of acquired immunity from self-recognition structures. Scand J Immunol 1976 0.75
152 [Biologically active peptides]. Duodecim 1976 0.75
153 Regular inheritance of Gc groups in 169 families and 184 mother-child combinations. Hum Hered 1969 0.75
154 Expression of VH antibody genes in different background genomes. Scand J Immunol 1978 0.75
155 Purification of pregnancy-specific beta 1-glycoprotein with a monoclonal antibody immunoadsorbent. J Immunol Methods 1983 0.75
156 Effect of insemination volume on uterine contractions and inflammatory response and on elimination of semen in the mare uterus-scintigraphic and ultrasonographic studies. J Vet Med A Physiol Pathol Clin Med 2005 0.75
157 Allotype-associated differences in concentrations of human IgA2. Scand J Immunol 1998 0.75
158 Transport of spermatozoa in the reproductive tracts of mares. J Reprod Fertil Suppl 2000 0.75
159 Antibody responses to hapten in thymectomized mice: extraordinarily pronounced deficiency in IgG1 production. Scand J Immunol 1989 0.75
160 [Immunoglobulins and their genes]. Duodecim 1983 0.75
161 [Cancer immunotherapy]. Duodecim 1976 0.75
162 [Nobel prize in physiology and medicine 1972. The structure of immunoglobulins]. Duodecim 1972 0.75
163 Linkage and recombination of VH gene markers, Np and Nb, in recombinant inbred strains of mice. Immunol Lett 1981 0.75
164 Use of lightly haptenated phage to detect high-affinity antibody. Scand J Immunol 1972 0.75
165 Natural anti-hapten antibodies. Med Biol 1974 0.75
166 [Cell hybridization - a new method for antibody production]. Duodecim 1980 0.75
167 [Regulation of the immune response]. Duodecim 1972 0.75
168 Antibody response by cultured spleen fragments from carrier-primed mice to hapten-protein conjugates. Scand J Immunol 1975 0.75
169 The role of B-cell memory in secondary IgG and IgM responses. Scand J Immunol 1976 0.75
170 Cytotoxic effect of anti-theta and anti-mouse specific B lymphocyte antigen (MBLA) antisera on helper cells and antibody-forming cell precursors in the immune response of mice to the 4-hydroxy-3,5-dinitrophenacetyl (NNP) hapten. Eur J Immunol 1972 0.75
171 ABO-specific autoagglutinins. Vox Sang 1970 0.75
172 Immunological methods based on antigen-coupled bacteriophages. J Immunol Methods 1980 0.75
173 Intrauterine fluid accumulation in oestrous mares. Acta Vet Scand 1997 0.75
174 Genetics of the anti-dextran B512 and the autoanti-idiotypic response: codominant expression in F1 hybrids and dichotomy of response and allotype-linked idiotype. Immunogenetics 1980 0.75