PubRank

N B Javitt

Author PubWeight™ 73.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Postprandial serum bile acid for the detection of hepatobiliary disease. JAMA 1973 2.23
2 Effect of sodium taurolithocholate on bile flow and bile acid exeretion. J Clin Invest 1968 1.95
3 Metabolism of cholest-5-ene-3 beta, 26-diol in the rat and hamster. J Biol Chem 1968 1.40
4 Ursodeoxycholic acid therapy: the baby and the bathwater. Hosp Pract (Off Ed) 1992 1.40
5 Bile acid synthesis in man: metabolism of 7 -hydroxycholesterol- 14 C and 26-hydroxycholesterol- 3 H. J Clin Invest 1972 1.33
6 Quantitative estimation os bile salts in serum. Can J Biochem 1970 1.27
7 Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity. Biochemistry 1995 1.18
8 Role of hepatic anion-binding protein in bromsulphthalein conjugation. J Exp Med 1973 1.17
9 Peroxisomal defects in neonatal-onset and X-linked adrenoleukodystrophies. Science 1985 1.15
10 Cholesterol gallstones and the chemical composition of bile in baboons. Ann Surg 1971 1.13
11 Cerebrotendinous xanthomatosis: reduced serum 26-hydroxycholesterol. J Lipid Res 1982 1.10
12 Cholestasis in rats induced by taurolithocholate. Nature 1966 1.09
13 Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin. J Lipid Res 1992 1.07
14 Morphologic changes in hamster liver during intrahepatic cholestasis induced by taurolithocholate. Lab Invest 1966 1.04
15 Cholestatic syndromes in infancy: diagnostic value of serum bile acid pattern and cholestyramine administration. Pediatr Res 1973 1.03
16 Composition of basal and stimulated hepatic bile in baboons, and the formation of cholesterol gallstones. Proc Natl Acad Sci U S A 1971 1.01
17 Immune complexes and IFN-gamma decrease cholesterol 27-hydroxylase in human arterial endothelium and macrophages. J Lipid Res 2001 1.00
18 27-hydroxycholesterol: production rates in normal human subjects. J Lipid Res 1999 0.99
19 Sterol 27-hydroxylase: expression in human arterial endothelium. J Lipid Res 1997 0.97
20 Bile acid synthesis in rat liver peroxisomes: metabolism of 26-hydroxycholesterol to 3 beta-hydroxy-5-cholenoic acid. J Lipid Res 1985 0.97
21 Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1. J Lipid Res 1999 0.96
22 Cholesterol and 27-hydroxycholesterol 7 alpha-hydroxylation: evidence for two different enzymes. J Lipid Res 1993 0.95
23 26-Hydroxycholesterol. Identification and quantitation in human serum. J Biol Chem 1981 0.95
24 Hepatic bile formation. (Second of two parts). N Engl J Med 1976 0.94
25 Bile salt regulation of hepatic excretory function. Gastroenterology 1969 0.93
26 Alpha(1)-fetoprotein in chronic liver disease. N Engl J Med 1974 0.92
27 Bile acid synthesis in man. II. Determination of 7 alpha-hydroxycholesterol, (22R)-22-hydroxycholesterol, and 26-hydroxycholesterol in human meconium. J Lipid Res 1977 0.91
28 Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions. J Biol Chem 1998 0.91
29 Diagnostic value of serum bile acids. Clin Gastroenterol 1977 0.89
30 Subcellular pathology of rat liver in cholestasis and choleresis induced by bile salts. 1. Effects of lithocholic, 3beta-hydroxy-5-cholenoic, cholic, and dehydrocholic acids. Lab Invest 1977 0.88
31 Biliary lipid excretion after hepatic portoenterostomy. Ann Surg 1976 0.86
32 7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis. J Lipid Res 1997 0.86
33 Ethereal and acyl glucuronide formation in the homozygous Gunn rat. Am J Physiol 1966 0.85
34 Serum bile acid patterns in neonatal hepatitis and extrahepatic biliary atresia. J Pediatr 1977 0.84
35 Metabolic pathways of bile acid formation in the rat. Mt Sinai J Med 1970 0.84
36 Parenteral nutrition and neonatal cholestasis. J Pediatr 1979 0.83
37 Cholic acid synthesis from 26-hydroxycholesterol and 3-hydroxy-5-cholestenoic acid in the rabbit. J Biol Chem 1989 0.83
38 Cholesterol metabolism: use of D2O for determination of synthesis rate in cell culture. J Lipid Res 1985 0.83
39 Hepatobiliary diseases associated with serum antimitochondrial antibody (AMA). Am J Med 1973 0.83
40 Hepatotoxicity of bile acids in rabbits: ursodeoxycholic acid is less toxic than chenodeoxycholic acid. Lab Invest 1982 0.82
41 Metabolism of taurolithocholic acid in the hamster. J Biol Chem 1967 0.82
42 Clinical and experimental aspects of sulphobromophthalein and related compounds. Prog Liver Dis 1970 0.82
43 Bile acid excretion in Dubin-Johnson syndrome. Gastroenterology 1978 0.81
44 26-hydroxycholesterol: regulation of hydroxymethylglutaryl-CoA reductase activity in Chinese hamster ovary cell culture. J Lipid Res 1983 0.81
45 Sterol 27-hydroxylase: high levels of activity in vascular endothelium. J Lipid Res 1994 0.81
46 Bile acid synthesis: down-regulation by monohydroxy bile acids. FASEB J 1988 0.81
47 Serum bile acid analysis: a rapid, direct enzymatic method using dual-beam spectrophotofluorimetry. J Lipid Res 1977 0.81
48 Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis. Gastroenterology 1998 0.80
49 Extrahepatic biliary atresia: diagnosis by serum bile acid patterns and response to cholestyramine. Surgery 1973 0.80
50 Oxysterols: 27-hydroxycholesterol and its radiolabeled analog. Steroids 2000 0.80
51 The cholestatic syndrome--1971. Am J Med 1971 0.80
52 Bile acids in human breast cyst fluid: the identification of lithocholic acid. J Clin Endocrinol Metab 1990 0.80
53 Hyperbilirubinemia and cholestasis. Am J Med 1978 0.79
54 Letter: Timing of cholestyramine doses in cholestatic liver disease. N Engl J Med 1974 0.79
55 Porphyrin-heme pathway: regulation by intermediates in bile acid synthesis. Science 1973 0.79
56 "Cheno" therapy for gallstones: where the Cooperative Study now stands. Hosp Pract 1976 0.79
57 Cholesterol metabolism. Effect of 26-thiacholesterol and 26-aminocholesterol, analogues of 26-hydroxycholesterol, on cholesterol synthesis and low-density-lipoprotein-receptor binding. Biochem J 1988 0.79
58 Solvolysis of chenodeoxycholic acid sulfates. Steroids 1981 0.79
59 Cimetidine cholestatic jaundice in children. J Surg Res 1978 0.78
60 Cholest-5-ene-3 beta, 26-diol: synthesis and biomedical use of a deuterated compound. Biomed Mass Spectrom 1982 0.78
61 Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol 1989 0.78
62 Chenodeoxycholic acid synthesis in the hamster: a metabolic pathway via 3 beta, 7 alpha-dihydroxy-5-cholen-24-oic acid. Steroids 1982 0.78
63 Bile acid analysis in biological fluids: a novel approach. J Lipid Res 1997 0.78
64 Bile acid synthesis. Metabolism of 3 beta-hydroxy-5-cholenoic acid in the hamster. J Biol Chem 1981 0.78
65 Effect of nafcillin on hepatic excretory function. Biochem Pharmacol 1983 0.77
66 Ethinyl estradiol: long term effects on bile acid kinetics in the baboon. Trans Assoc Am Physicians 1975 0.77
67 Cholestasis in infancy. Status report and conceptual approach. Gastroenterology 1976 0.77
68 Chenodeoxycholic acid-3-sulfate. Metabolism and excretion in the rat and hamster and effects on hepatic transport systems. Biochem Pharmacol 1983 0.77
69 Intrahepatic cholestasis: a functional approach to pathogenesis. Gastroenterology 1967 0.77
70 Dibromsulphalein (DBSP) estimation of hepatic transport function in man. Eur J Clin Invest 1974 0.77
71 Bile acid synthesis: 7 alpha-hydroxylation of intermediates in the sterol 27-hydroxylase metabolic pathway. J Lipid Res 1996 0.77
72 Editorial: Chronic active hepatitis. Am J Med 1973 0.77
73 Reevaluation of the effects of cytochalasins on steroidogenesis: studies on hamster granulosa cells. Endocrinology 1984 0.77
74 Bile acid excretion: the alternate pathway in the hamster. J Clin Invest 1977 0.77
75 Bile acid synthesis. Metabolism of 3 beta-hydroxy-5-cholenoic acid to chenodeoxycholic acid. J Biol Chem 1986 0.77
76 Hepatic bile formation (first of two parts). N Engl J Med 1976 0.77
77 Bile salts and liver disease in childhood. Postgrad Med J 1974 0.75
78 Cholestasis of pregnancy: ursodeoxycholic acid therapy. J Hepatol 1998 0.75
79 Role of hepatic bile composition in gallstone formation in baboons. Ann Surg 1973 0.75
80 Polyethylene glycol 900: useful marker rather than notable exception. Gastroenterology 1992 0.75
81 Studies of lipoprotein-X (LP-X) and bile acids in familial LCAT deficiency. Preliminary report. Acta Med Scand 1973 0.75
82 Cholic acid synthesis from 27-hydroxycholesterol in humans. Gastroenterology 1998 0.75
83 Bile salt synthesis in transplanted human liver. Gastroenterology 1971 0.75
84 Lithotripsy: a medical cholecystotomy. Hosp Pract (Off Ed) 1988 0.75
85 Symposium on bile salts. Foreword. Am J Med 1971 0.75
86 Metabolite regulation of cholesterol synthesis. Hosp Pract (Off Ed) 1985 0.75
87 Prolonged neonatal cholestasis: bile acid pattern and response to cholestyramine. Mt Sinai J Med 1979 0.75
88 Ethinyl estradiol: long term effects on bile acid kinetics in the baboon. Trans Assoc Am Physicians 1975 0.75
89 Lithocholic acid: notes on purification. J Lipid Res 1980 0.75
90 Hyperbilirubinemic and cholestatic syndromes. New concepts aiding recognition and management. Postgrad Med 1979 0.75
91 26-Hydroxycholesterol disulfate: metabolism and excretion in the normal neonate. J Steroid Biochem 1986 0.75
92 Excretion of bromsulphalein and depletion of hepatic glutathione in the rat. Australas Ann Med 1968 0.75
93 The Cheno Cooperative Study: its meaning for gallstone treatment. Hosp Pract (Off Ed) 1982 0.75
94 Cholestatic liver disease and its management. Baillieres Clin Gastroenterol 1989 0.75
95 Cholesterol 26-hydroxylase activity of hamster liver mitochondria: isotope ratio analysis using deuterated 26-hydroxycholesterol. J Lipid Res 1990 0.75
96 Metabolism of 3 beta-hydroxycholest-5-en-26-oic acid in hamsters. Experientia 1990 0.75
97 Quantitative estimation of hemolytic activity in vitro using 51 Cr-tagged erythrocytes. Clin Chim Acta 1971 0.75
98 Bile alcohols in perspective. Hepatology 1984 0.75
99 Clinical aspects of bile acid metabolism. Schweiz Med Wochenschr 1968 0.75
100 Leukopenia associated with mebendazole therapy of hydatid disease. Am J Trop Med Hyg 1980 0.75
101 Formation of a metabolite of dibromosulfophthalein (DBSP) in man. Eur J Clin Pharmacol 1983 0.75
102 Biliary dyskinesia: mechanisms and management. Hosp Pract (Hosp Ed) 1982 0.75
103 Selected topics in gastroenterology: A brief symposium. Prim Care 1976 0.75
104 Cholestatic jaundice. Med Clin North Am 1975 0.75
105 Hepatic heterogeneity: backward perfusion--a forward step. Lab Invest 1987 0.75
106 Cholecystadenoma and the use of cholecystokinin. J Pediatr 1971 0.75
107 Cholestatic liver disease: mechanisms, diagnosis and therapy. Adv Intern Med 1980 0.75
108 Quantitative analysis of unconjugated and conjugated bile acids in duodenal fluid by densitometry after paper electrophoresis. J Lipid Res 1973 0.75
109 Bile acid synthesis in HepG2 cells: effect of cyclosporin. J Lipid Res 1994 0.75
110 Clinical strategy for the hepatitides. Hosp Pract 1978 0.75
111 Trends in neonatal liver and gastrointestinal surgery. Clin Gastroenterol 1977 0.75
112 Rapid synthesis of 26-hydroxycholesterol from mevalonic acid in the Syrian hamster. Biochim Biophys Acta 1984 0.75