|
1
|
A high-resolution map of human evolutionary constraint using 29 mammals.
|
Nature
|
2011
|
8.67
|
|
2
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Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage.
|
Cell
|
2012
|
4.22
|
|
3
|
The UCSC Archaeal Genome Browser.
|
Nucleic Acids Res
|
2006
|
2.65
|
|
4
|
Reconstructing the microbial diversity and function of pre-agricultural tallgrass prairie soils in the United States.
|
Science
|
2013
|
2.62
|
|
5
|
PhylOTU: a high-throughput procedure quantifies microbial community diversity and resolves novel taxa from metagenomic data.
|
PLoS Comput Biol
|
2011
|
2.54
|
|
6
|
PHAST and RPHAST: phylogenetic analysis with space/time models.
|
Brief Bioinform
|
2010
|
2.36
|
|
7
|
Novel bacterial taxa in the human microbiome.
|
PLoS One
|
2012
|
2.35
|
|
8
|
Multiple testing. Part I. Single-step procedures for control of general type I error rates.
|
Stat Appl Genet Mol Biol
|
2004
|
2.34
|
|
9
|
Hotspots of biased nucleotide substitutions in human genes.
|
PLoS Biol
|
2009
|
1.89
|
|
10
|
The bovine lactation genome: insights into the evolution of mammalian milk.
|
Genome Biol
|
2009
|
1.77
|
|
11
|
Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion.
|
Genome Res
|
2007
|
1.72
|
|
12
|
Chromatin remodelling complex dosage modulates transcription factor function in heart development.
|
Nat Commun
|
2011
|
1.69
|
|
13
|
Chromosomal haplotypes by genetic phasing of human families.
|
Am J Hum Genet
|
2011
|
1.58
|
|
14
|
Augmentation procedures for control of the generalized family-wise error rate and tail probabilities for the proportion of false positives.
|
Stat Appl Genet Mol Biol
|
2004
|
1.55
|
|
15
|
Multiple testing. Part II. Step-down procedures for control of the family-wise error rate.
|
Stat Appl Genet Mol Biol
|
2004
|
1.47
|
|
16
|
Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells.
|
Mol Cell
|
2013
|
1.40
|
|
17
|
Ongoing GC-biased evolution is widespread in the human genome and enriched near recombination hot spots.
|
Genome Biol Evol
|
2011
|
1.36
|
|
18
|
Identifying genetic networks underlying myometrial transition to labor.
|
Genome Biol
|
2005
|
1.28
|
|
19
|
Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients.
|
BMC Genomics
|
2008
|
1.24
|
|
20
|
Gene regulatory networks in lactation: identification of global principles using bioinformatics.
|
BMC Syst Biol
|
2007
|
1.23
|
|
21
|
The phylogenetic diversity of metagenomes.
|
PLoS One
|
2011
|
1.21
|
|
22
|
Novel genes exhibit distinct patterns of function acquisition and network integration.
|
Genome Biol
|
2010
|
1.19
|
|
23
|
Average genome size estimation improves comparative metagenomics and sheds light on the functional ecology of the human microbiome.
|
Genome Biol
|
2015
|
1.13
|
|
24
|
Global marine bacterial diversity peaks at high latitudes in winter.
|
ISME J
|
2013
|
1.10
|
|
25
|
The importance of being cis: evolution of orthologous fish and mammalian enhancer activity.
|
Mol Biol Evol
|
2010
|
1.08
|
|
26
|
Transcriptional map of respiratory versatility in the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.
|
J Bacteriol
|
2008
|
1.06
|
|
27
|
Many human accelerated regions are developmental enhancers.
|
Philos Trans R Soc Lond B Biol Sci
|
2013
|
1.03
|
|
28
|
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.
|
Aging (Albany NY)
|
2011
|
1.01
|
|
29
|
Substitution patterns are GC-biased in divergent sequences across the metazoans.
|
Genome Biol Evol
|
2011
|
0.99
|
|
30
|
Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster.
|
Genome Res
|
2008
|
0.99
|
|
31
|
Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution.
|
PLoS One
|
2011
|
0.99
|
|
32
|
The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome.
|
Mol Biol Evol
|
2011
|
0.98
|
|
33
|
ProteinHistorian: tools for the comparative analysis of eukaryote protein origin.
|
PLoS Comput Biol
|
2012
|
0.97
|
|
34
|
A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes.
|
PLoS Genet
|
2013
|
0.97
|
|
35
|
How old is my gene?
|
Trends Genet
|
2013
|
0.91
|
|
36
|
Sifting through genomes with iterative-sequence clustering produces a large, phylogenetically diverse protein-family resource.
|
BMC Bioinformatics
|
2012
|
0.90
|
|
37
|
GC-biased evolution near human accelerated regions.
|
PLoS Genet
|
2010
|
0.89
|
|
38
|
Noncoding sequences near duplicated genes evolve rapidly.
|
Genome Biol Evol
|
2010
|
0.88
|
|
39
|
Analysis of human accelerated DNA regions using archaic hominin genomes.
|
PLoS One
|
2012
|
0.87
|
|
40
|
Exome capture from saliva produces high quality genomic and metagenomic data.
|
BMC Genomics
|
2014
|
0.86
|
|
41
|
Evaluation of two methods to estimate and monitor bird populations.
|
PLoS One
|
2008
|
0.85
|
|
42
|
Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach.
|
BMC Neurosci
|
2007
|
0.82
|
|
43
|
G-NEST: a gene neighborhood scoring tool to identify co-conserved, co-expressed genes.
|
BMC Bioinformatics
|
2012
|
0.82
|
|
44
|
A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design.
|
Genome Biol
|
2013
|
0.81
|
|
45
|
From genes to milk: genomic organization and epigenetic regulation of the mammary transcriptome.
|
PLoS One
|
2013
|
0.79
|
|
46
|
Beyond classification: gene-family phylogenies from shotgun metagenomic reads enable accurate community analysis.
|
BMC Genomics
|
2013
|
0.77
|
|
47
|
Features that define the best ChIP-seq peak calling algorithms.
|
Brief Bioinform
|
2016
|
0.76
|
|
48
|
Composite interval mapping to identify quantitative trait loci for point-mass mixture phenotypes.
|
Genet Res (Camb)
|
2010
|
0.75
|