Published in Neuron on February 03, 2005
Economic, neurobiological, and behavioral perspectives on building America's future workforce. Proc Natl Acad Sci U S A (2006) 5.31
cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action. Pharmacol Rev (2010) 3.27
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Local, persistent activation of Rho GTPases during plasticity of single dendritic spines. Nature (2011) 2.42
Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation. J Cell Biol (2009) 2.25
Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct (2007) 1.93
A GluR1-cGKII interaction regulates AMPA receptor trafficking. Neuron (2007) 1.83
Rho is a presynaptic activator of neurotransmitter release at pre-existing synapses in C. elegans. Genes Dev (2006) 1.29
Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent manner. J Cell Biol (2006) 1.24
Extinction: [corrected] does it or doesn't it? The requirement of altered gene activity and new protein synthesis. Biol Psychiatry (2006) 1.14
A mechanism underlying AMPA receptor trafficking during cerebellar long-term potentiation. Proc Natl Acad Sci U S A (2005) 1.11
The role of nitric oxide in pre-synaptic plasticity and homeostasis. Front Cell Neurosci (2013) 1.11
Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction. J Biol Chem (2009) 1.10
Synaptic plasticity and NO-cGMP-PKG signaling regulate pre- and postsynaptic alterations at rat lateral amygdala synapses following fear conditioning. PLoS One (2010) 1.00
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Two sides to long-term potentiation: a view towards reconciliation. Philos Trans R Soc Lond B Biol Sci (2013) 0.93
Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex. PLoS Genet (2011) 0.91
Role of nitric oxide in classical conditioning of siphon withdrawal in Aplysia. J Neurosci (2007) 0.91
Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci (2015) 0.89
Recruitment of resting vesicles into recycling pools supports NMDA receptor-dependent synaptic potentiation in cultured hippocampal neurons. J Physiol (2012) 0.88
Synaptic plasticity and NO-cGMP-PKG signaling coordinately regulate ERK-driven gene expression in the lateral amygdala and in the auditory thalamus following Pavlovian fear conditioning. Learn Mem (2010) 0.87
Presynaptic and postsynaptic Ca(2+) and CamKII contribute to long-term potentiation at synapses between individual CA3 neurons. Proc Natl Acad Sci U S A (2006) 0.87
Nitric oxide synthase mediates the ability of darbepoetin alpha to improve the cognitive performance of STOP null mice. Neuropsychopharmacology (2010) 0.87
Early presynaptic changes during plasticity in cultured hippocampal neurons. EMBO J (2006) 0.87
Rapid and long-lasting increase in sites for synapse assembly during late-phase potentiation in rat hippocampal neurons. PLoS One (2009) 0.87
A novel role for cyclic guanosine 3',5'monophosphate signaling in synaptic plasticity: a selective suppressor of protein kinase A-dependent forms of long-term potentiation. Neuroscience (2006) 0.86
Cellular targets of nitric oxide in the hippocampus. PLoS One (2013) 0.85
Nitric oxide mediates local activity-dependent excitatory synapse development. Proc Natl Acad Sci U S A (2013) 0.83
A role for nitric oxide-driven retrograde signaling in the consolidation of a fear memory. Front Behav Neurosci (2010) 0.83
Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse. PLoS One (2007) 0.83
CNF1 increases brain energy level, counteracts neuroinflammatory markers and rescues cognitive deficits in a murine model of Alzheimer's disease. PLoS One (2013) 0.83
The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activation. Cell Death Differ (2014) 0.83
Age-dependent glutamate induction of synaptic plasticity in cultured hippocampal neurons. Learn Mem (2006) 0.83
A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity. Channels (Austin) (2008) 0.82
CNF1 improves astrocytic ability to support neuronal growth and differentiation in vitro. PLoS One (2012) 0.82
Piccolo Directs Activity Dependent F-Actin Assembly from Presynaptic Active Zones via Daam1. PLoS One (2015) 0.82
cGMP Signaling, Phosphodiesterases and Major Depressive Disorder. Curr Neuropharmacol (2011) 0.81
NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury. Neurobiol Dis (2012) 0.81
Rapid increase in clusters of synaptophysin at onset of homosynaptic potentiation in Aplysia. Proc Natl Acad Sci U S A (2011) 0.81
NADPH-diaphorase histochemical changes in the hippocampus, cerebellum and striatum are correlated with different modalities of exercise and watermaze performances. Exp Brain Res (2006) 0.81
Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. J Neuroimmune Pharmacol (2009) 0.80
Information maintenance in working memory: an integrated presentation of cognitive and neural concepts. Front Syst Neurosci (2015) 0.79
The E. coli CNF1 as a pioneering therapy for the central nervous system diseases. Toxins (Basel) (2014) 0.79
Inhibition of the Rho/Rho kinase pathway prevents lipopolysaccharide-induced hyperalgesia and the release of TNF-α and IL-1β in the mouse spinal cord. Sci Rep (2015) 0.78
Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric oxide production during the ovarian cycle. Endocrinology (2010) 0.78
The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells. Biochim Biophys Acta (2013) 0.78
Is there a role for nitric oxide in methamphetamine-induced dopamine terminal degeneration? Neurotox Res (2013) 0.78
Myosin IXa Binds AMPAR and Regulates Synaptic Structure, LTP, and Cognitive Function. Front Mol Neurosci (2016) 0.78
Nitric oxide-dependent long-term depression but not endocannabinoid-mediated long-term potentiation is crucial for visual recognition memory. J Physiol (2013) 0.78
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures. J Neurochem (2009) 0.77
Enhanced nitric oxide production during lead (Pb²⁺) exposure recovers protein expression but not presynaptic localization of synaptic proteins in developing hippocampal neurons. Brain Res (2011) 0.77
Why is nitric oxide important for our brain? Funct Neurol (2016) 0.76
Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia. BMC Neurosci (2015) 0.76
The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses. Neural Plast (2011) 0.76
Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology. Sci Rep (2016) 0.75
Phosphatidic acid and neurotransmission. Adv Biol Regul (2016) 0.75
Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol (2016) 0.75
Hyperpolarization-activated, cyclic nucleotide-gated cation channels in Aplysia: Contribution to classical conditioning. Proc Natl Acad Sci U S A (2015) 0.75
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc Natl Acad Sci U S A (2006) 5.83
Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala. Neuron (2006) 5.79
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron (2004) 5.35
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron (2004) 4.21
A neuronal isoform of the aplysia CPEB has prion-like properties. Cell (2003) 4.16
Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. Neuron (2006) 4.03
Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron (2004) 3.26
A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia. Cell (2003) 3.15
Increased attention to spatial context increases both place field stability and spatial memory. Neuron (2004) 3.12
Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell (2002) 3.10
Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory. Neuron (2002) 2.87
Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture. Cell (2002) 2.77
A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell (2012) 2.72
Aplysia CPEB can form prion-like multimers in sensory neurons that contribute to long-term facilitation. Cell (2010) 2.65
Neuronal transcriptome of Aplysia: neuronal compartments and circuitry. Cell (2006) 2.61
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res (2002) 2.56
The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. Blood (2012) 2.47
Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses. Neuron (2003) 2.42
Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala. Neuron (2002) 2.34
CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum. Proc Natl Acad Sci U S A (2005) 2.28
The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells. Cell (2003) 2.24
Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell (2002) 2.09
Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage. Cell (2011) 2.05
Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation. Proc Natl Acad Sci U S A (2004) 2.01
Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo. Neuron (2004) 1.98
Molecular mechanism for a gateway drug: epigenetic changes initiated by nicotine prime gene expression by cocaine. Sci Transl Med (2011) 1.97
Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48. Sci Transl Med (2013) 1.97
Grid cells use HCN1 channels for spatial scaling. Cell (2011) 1.97
Paradoxical influence of hippocampal neurogenesis on working memory. Proc Natl Acad Sci U S A (2007) 1.96
Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation. Catheter Cardiovasc Interv (2003) 1.95
The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth. Neuron (2004) 1.94
Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci U S A (2002) 1.88
Presynaptic activation of silent synapses and growth of new synapses contribute to intermediate and long-term facilitation in Aplysia. Neuron (2003) 1.85
A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context. Neuron (2006) 1.83
Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice. Circ Res (2003) 1.82
Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture. Neuron (2005) 1.80
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins. Neuron (2003) 1.80
Increased size and stability of CA1 and CA3 place fields in HCN1 knockout mice. Neuron (2011) 1.77
Essential role of coiled coils for aggregation and activity of Q/N-rich prions and PolyQ proteins. Cell (2010) 1.76
Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility. Neuron (2008) 1.74
Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance. J Am Coll Cardiol (2003) 1.73
Platelet protein interactions: map, signaling components, and phosphorylation groundstate. Arterioscler Thromb Vasc Biol (2008) 1.71
Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory. Neuron (2003) 1.71
Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia. Neuron (2011) 1.70
stathmin, a gene enriched in the amygdala, controls both learned and innate fear. Cell (2005) 1.69
Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene. Learn Mem (2004) 1.69
Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing. J Neurosci (2007) 1.66
Molecular mechanisms of memory storage in Aplysia. Biol Bull (2006) 1.64
Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus. Proc Natl Acad Sci U S A (2003) 1.61
An unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs. J Neurosci (2003) 1.61
Downregulation of cytoskeletal muscle LIM protein by nitric oxide: impact on cardiac myocyte hypertrophy. Circulation (2003) 1.60
Active Rho kinase (ROK-alpha ) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J Biol Chem (2001) 1.58
Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance. Neuropharmacology (2004) 1.57
Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors. Proc Natl Acad Sci U S A (2004) 1.57
The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. Proc Natl Acad Sci U S A (2004) 1.57
Distinct neural signatures for safety and danger in the amygdala and striatum of the mouse. Neuron (2005) 1.57
M(3) muscarinic receptor expression on suburothelial interstitial cells. BJU Int (2009) 1.55
alpha-Synuclein produces a long-lasting increase in neurotransmitter release. EMBO J (2004) 1.54
Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals. Proc Natl Acad Sci U S A (2008) 1.54
Activity-dependent presynaptic facilitation and hebbian LTP are both required and interact during classical conditioning in Aplysia. Neuron (2003) 1.51
Single L-type Ca(2+) channel regulation by cGMP-dependent protein kinase type I in adult cardiomyocytes from PKG I transgenic mice. Cardiovasc Res (2003) 1.51
Synaptic remodeling, synaptic growth and the storage of long-term memory in Aplysia. Prog Brain Res (2008) 1.50
Thrombin and collagen induce a feedback inhibitory signaling pathway in platelets involving dissociation of the catalytic subunit of protein kinase A from an NFkappaB-IkappaB complex. J Biol Chem (2010) 1.47
An animal model of a behavioral intervention for depression. Neuron (2008) 1.46
Normalization of nomenclature for peptide motifs as ligands of modular protein domains. FEBS Lett (2002) 1.46
Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected]. Circulation (2003) 1.45
Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia. Neuron (2008) 1.44
A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB. Learn Mem (2004) 1.43
Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice. Learn Mem (2004) 1.43
ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay. Thromb Haemost (2008) 1.40
Synapses and memory storage. Cold Spring Harb Perspect Biol (2012) 1.39
Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. Mol Cell Proteomics (2005) 1.38
Attention enhances the retrieval and stability of visuospatial and olfactory representations in the dorsal hippocampus. PLoS Biol (2009) 1.37
cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons. J Neurosci (2007) 1.37
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. Free Radic Biol Med (2005) 1.36
Common molecular mechanisms in explicit and implicit memory. J Neurochem (2006) 1.35
Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes. J Cell Biol (2008) 1.35
Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte. J Biol Chem (2006) 1.33
A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex. Cell (2008) 1.32
Modeling cognitive endophenotypes of schizophrenia in mice. Trends Neurosci (2009) 1.32
Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity. Nat Neurosci (2009) 1.31
Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2004) 1.31
Serotonin-induced regulation of the actin network for learning-related synaptic growth requires Cdc42, N-WASP, and PAK in Aplysia sensory neurons. Neuron (2005) 1.31
EVH1 domains: structure, function and interactions. FEBS Lett (2002) 1.31
Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. J Biol Chem (2004) 1.30
Dscam mediates remodeling of glutamate receptors in Aplysia during de novo and learning-related synapse formation. Neuron (2009) 1.29